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7427416 |
Methods of treating conditions using metal-containing materials
Methods of treating conditions using metal-containing materials are disclosed. Exemplary conditions include bacterial conditions, biofilm conditions, microbial conditions, inflammatory conditions,...
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7381419 |
Medical composition kit for treating lesioned abnormal tissue
Optimum compounding composition of a local injection preparation for treating rectal submucous lesioned abnormal tissue with local anesthetic is decided to provide a medical composition kit. In a...
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7341741 |
Pharmaceutical composition for the treatment of inflammatory bowel disease
A polysaccharide selected from xanthan gum and HPMC is used for the treatment or prophylaxis of IBD, especially Crohn's Disease, left-sided ulcerative colitis or pouchitis.
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7341737 |
Medicated tampon
A tampon adapted to deliver a therapeutic agent, the tampon including a tampon body having a distal end; and a dosage form affixed to the distal end of the tampon body, wherein the dosage form...
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7332177 |
Method and formulation for treating resistance to antihypertensives and related conditions
A method for the prevention or treatment of symptoms of hypertension in a patient who is resistant to antihypertensive effects of an antihypertensive compound administered in the absence of...
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7320800 |
Vaginally administrable progesterone-containing tablets and method for preparing same
The present invention provides a method for preparing a tablet for the vaginal administration of progesterone for systemic use. The method comprises first mixing water with micronized progesterone,...
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7255881 |
Metal-containing materials
Metal-containing materials, as well as their preparation and use are disclosed. The metal-containing material can be, for example, an antimicrobial material, an anti-biofilm material, an...
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7226622 |
Chemoablation of tissue using biodegradable, solid salt dosage forms
Novel methods for the chemical ablation of tissue (e.g. prostatic tissue) are described. These methods include the steps of: (a) providing one or more solid salt dosage form comprising 50-100% w/w...
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7214381 |
Composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels
The present invention refers to a pharmaceutical composition suitable for the transdermal or transmucosal administration of one or more active agents, in form of a gel or a solution, comprising as...
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7166605 |
Probucol nitro-derivatives
Probucol derivatives and pharmaceutical compositions containing the same to be employed in treatment or prophylaxis of diseases.
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7135191 |
Urogenital or anorectal transmucosal vaccine delivery system
The invention is directed to a suppository based vaccine delivery system for immunizing against urogenital and anorectally transmitted infectious disease in humans and animals and a method for...
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7135190 |
Mixtures of various triblock polyester polyethylene glycol copolymers having improved gel properties
A water soluble, biodegradable reverse thermal gelation system comprising a mixture of at least two types of tri-block copolymer components is disclosed. The tri-block copolymer components are made...
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7087249 |
Treatment of mucosal membranes
The invention relates to the use of one or more antimicrobial metals preferably selected from silver, gold, platinum, and palladium but most preferably silver, formed with atomic disorder, and...
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7056495 |
Solid dose delivery vehicle and methods of making same
The present invention encompasses a solid dose delivery vehicle for ballistic administration of a bioactive material to subcutaneous and intradermal tissue, the delivery vehicle being sized and...
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7045140 |
Therapeutic delivery of carbon monoxide
Metal carbonyls are used to deliver CO having biological activity, for example vasodilatation and inhibition of transplant rejection. The metal of the carbonyl is typically of groups 7 to 10, e.g....
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7022335 |
Suppository of retaining in lower region of rectum
A suppository of retaining in a lower region of rectum, which contains a suppository base containing:
(A) a fatty acid triglyceride, (B) one or more C 14-18 fatty acid glycerides, and (C) a base...
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7001609 |
Mucosal originated drug delivery systems and animal applications
The present invention is directed to mucosal originated drug delivery systems and methods for using the drug delivery system to treat conditions in animals. Conditions amenable to treatment...
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6986901 |
Gastrointestinal compositions
The invention relates to compositions and methods for treating and/or preventing lower gastrointestinal (GI) disorders in mammalian patients, more particularly for alleviating and/or preventing the...
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6962717 |
Pharmaceutical compositions
A pharmaceutical composition for slow release of active ingredient in the gastrointestinal tract, comprising a plurality of active ingredient-containing particles coated with a material insoluble...
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6949255 |
Inhibitory chemical formulation with preservative system
The present invention provides methods for preventing the transmission of HIV, methods for prophylaxis of HIV transmission and methods for reducing the risk of HIV transmission vaginally or...
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6939563 |
Non-fermented osmotic laxative and method for treating and preventing colorectal cancers
Use of a non-fermented osmotic laxative as an active agent for preparation of a medicinal product for treating and/or preventing colon and/or rectum cancers. A method of treating or preventing...
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6923988 |
Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
The present invention provides solid pharmaceutical compositions for improved delivery of a wide variety of pharmaceutical active ingredients contained therein or separately administered. In one...
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6890547 |
Glycyrrhizin preparations for transmucosal absorption
By blending glycyrrhizin with an ester mixture comprising a C 6-18 fatty acid glycerol ester with a C 6-18 fatty acid macrogol ester, glycyrrhizin can be efficiently absorbed via mucosae, in...
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6861066 |
Method for the delivery of a biologically active agent
A method of manufacturing a stable nanosuspension for delivery of a biologically active agent into the bloodstream of a subject is disclosed. A microfluidizable mixture is initially formed and...
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6861060 |
Personal care formulations
Personal care and hygiene formulations for topical application to mucosal surfaces. These formulations include an amphiphilic lipid carrier in the form of a colloidal composition which can include...
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6841169 |
Stabilizer for pharmacons
The present invention relates to an auxiliary substance for an active substance, such as a pharmacon. The auxiliary substance has a stabilizing action. The auxiliary substance further has a...
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6800663 |
Crosslinked hydrogel copolymers
The present invention relates to crosslinked polymers, synthesized through ring-opening polymerization of ethylenically unsaturated epoxides, in combination with α-hydroxy acids using a...
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6761903 |
Clear oil-containing pharmaceutical compositions containing a therapeutic agent
The present invention relates to pharmaceutical compositions and methods for improved solubilization of triglycerides and improved delivery of therapeutic agents. Compositions of the present...
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6749856 |
Mucosal cytotoxic T lymphocyte responses
The invention provides methods for induction of an antigen-specific, mucosal cytotoxic T lymphocyte response useful in preventing and treating infections with pathogens that gain entry via a...
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6740333 |
Suppository and composition comprising at least one polyethylene glycol
There is provided a suppository comprising at least one biocompatible polymer, wherein the biocompatible polymer is essentially non-biodegradable, and wherein the suppository essentially does not...
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6699495 |
Methods for treating multiple sclerosis employing desmethylselegiline
Methods and pharmaceutical compositions for using desmethylselegiline. In particular, the present invention provides novel compositions and methods for using desmethylselegiline for...
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6696071 |
Pre-coital and post-coital rinse with anti-viral and skin-protective zinc salts
An aqueous douche or enema is disclosed, containing a water-soluble zinc salt at an anti-viral concentration, designed for use shortly before and/or shortly after intercourse. Unlike a lubricant...
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6667058 |
Oral forms of administration containing solid flupirtine with controlled release of active substance
Pharmaceutical dosage units containing flupirtine or a pharmaceutically acceptable salt of flupirtine with controlled release of active substance using a delayed-action or controlled-release...
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6652884 |
Method for the treatment of solid tumors by albumin microparticles incorporating paclitaxel
The invention concerns a method for the treatment of tumors sensitive to Paclitaxel, by intra-arterial injections of dispersions of microparticles of albumin incorporating Paclitaxel in...
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6638498 |
Molecularly imprinted polymers for the treatment and diagnosis of medical conditions
Improved molecularly imprinted polymers (MIPs) with both higher and more specific binding capacity for particular bile acids and/or salts, including the synthesis of such MIPs, the compounds...
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6607742 |
Suppository composition which is a spray-dried suspension of an acid-labile proton pump inhibitor in a solvent solution of a sterol and polymer
Acid-labile active compounds are prepared in suppository form, particularly for rectal administration.
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6602519 |
Oxidized thymosin β4
The present invention relates to the use of oxidized thymosin β4 in therapy, more particularly in the treatment of diseases or conditions associated with an inflammatory response of septic shock.
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6596297 |
Biodegradable microbicidal vaginal barrier device
An intravaginal bio-erodible microbicidal barrier device. The device comprises (a) at least one micronized compound selected from the group consisting of cellulose acetate phthalate and...
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6592894 |
Hydrogel-isolated cochleate formulations, process of preparation and their use for the delivery of biologically relevant molecules
A process for producing a small-sized, lipid-based cochleate. Cochleates are derived from liposomes which are suspended in an aqueous two-phase polymer solution, enabling the differential...
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6585996 |
Lipid-soluble thiamine derivatives in the treatment of autism
The present invention is directed to a method for the treatment of autism comprising administering to a person in need of such treatment a therapeutically effective amount of a lipid-soluble...
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6576250 |
Pharmaceutical compositions for rectal and vaginal administration
The pharmaceutical compositions of the present invention comprise rectally and vaginally administerable dosage forms that contain effervescent agents as penetration enhancers for drugs....
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6569463 |
Solid carriers for improved delivery of hydrophobic active ingredients in pharmaceutical compositions
The present invention provides solid pharmaceutical compositions for improved delivery of a wide variety of pharmaceutical active ingredients contained therein or separately administered. In one...
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6565889 |
Bilayer structure which encapsulates multiple containment units and uses thereof
The present invention provides compositions and methods of preparing a bilayer structure for encapsulating multiple containment units. These containment units can contain therapeutic, diagnostic...
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6544550 |
Medicaments for gastrointestinal disorders
The invention relates to the co-administration in human or veterinary medicine of 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)me
thyl]-4H-carbazol-4-one or a physiologically...
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6528082 |
Methods and pharmaceutical compositions employing desmethylselegiline to treat neoplastic diseases or conditions
The application is directed to the treatment of neoplastic diseases or conditions by administering R(−) desmethylselegiline, S(+) desmethylselegiline, or a combination of the two. Neoplastic...
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6500461 |
Particulate formulations
This invention provides vehicles capable of delivering high concentrations of poorly hydrophilic/poorly lipophilic compounds to animals, by combining compounds having biocompatible hydrophobic...
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6491942 |
Suppositories
The present invention provides a suppository comprising a hydrophobic hydroxypropyl methylcellulose. The present invention is useful as a suppository base which has little interaction with a drug...
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6488954 |
Liquid suppository composition of diclofenac sodium
The present invention relates to a liquid suppository composition comprising diclofenac sodium, poloxamer and at least one polymer select from the group consisting of polyethylene oxide and...
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6479045 |
Vaginal pH buffering for preventing miscarriage and premature labor, by treating or preventing bacterial vaginosis
The present invention concerns compositions and methods for preventing miscarriage and premature labor, and for treating and preventing Bacterial Vaginosis using a pH-buffering polymer. The present...
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6476059 |
Use of polycyclic 2-aminothiazole systems for the treatment of obesity
The invention relates to the use of polycyclic 2-aminothiazole systems and their physiologically tolerated salts and physiologically functional derivatives for the treatment of obesity. The...
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