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5538738 |
Retard systems for the sustained release of medicinal and/or biological valuable materials from a depot carrier material
The invention relates to the use of free radical-reactive cross-linker components based on olefinically unsaturated esters of lower hydroxycarboxylic acids and/or oligomers thereof for modifying...
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5520921 |
Periodontal packing device
A periodontal packing device is provided comprising a plate having two through holes for a thread. A second set of holes can be provided for packing material. The thread is passed through the two...
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5520924 |
Methods and articles for administering drug to the oral cavity
The present invention features methods and articles of manufacture for delivering drug to the oral cavity. The methods and articles feature drug held in a polyvinyl alcohol matrix. The matrix...
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5518731 |
Nonaqueous fluorinated drug delivery vehicle suspensions
Nonaqueous pharmaceutical compositions for use in aqueous physiological systems are disclosed comprising drug delivery vehicles suspended in nonaqueous perfluorocarbon or fluorinated silicone...
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5518735 |
Meta-substituted phenylalanine derivatives
D,L-, L- and D-phenyl alanine derivatives of formula (I) defined in claim 1 in which R 1 is an amidino-, guanidino-, oxamidino-, aminomethyl- or amino group have been discovered which effectively...
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5518730 |
Biodegradable controlled release flash flow melt-spun delivery system
Biodegradable controlled release delivery systems using melt-spun biodegradable polymers as carriers for bio-effecting agents such as pharmaceutical actives are disclosed. Oral dosage forms as well...
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5516523 |
Transmucosal delivery of macromolecular drugs
A method and system for mucosally administering a macromolecular drug to mucosa of the oral cavity is shown. The system comprises an inner drug/enhancer/polymer layer having one surface adapted to...
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5512290 |
Compositions containing 2-acetyl-1-pyrroline
A powder-form composition of 2-acetyl-1-pyrroline incorporated with a support of maltodextrin and/or cyclodextrin. The composition is prepared by hydrolyzing a 2-(1-alkoxyethenyl)-1-pyrroline with...
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5512293 |
Oral sustained release drug delivery device
This invention pertains to a sustained release delivery device for delivering a beneficial agent into the oral cavity of a patient. More particularly, the invention relates to a device comprising...
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5500228 |
Phase separation-microencapsulated pharmaceuticals compositions useful for alleviating dental disease
Oral compositions for the local administration of a therapeutic agent to a periodontal pocket of a patient for alleviating dental disease comprise a plurality of dry, discrete microparticles each...
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5496559 |
Porous solid formulations containing proteinaceous physiologically active substances
A solid formulation for buccal or oral administration which contains a proteinaceous physiologically active substance as an active ingredient, as well as collagen and a water-soluble additive, said...
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5496558 |
Solid form xerostomia product
A solid dosage form for relieving xerostomia symptoms comprising a lubricating polymer comprising polyethylene oxide and a sialogogue in a pharmaceutically acceptable, substantially non-cariogenic,...
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5492937 |
Gel-forming liquid carrier composition
A carrier composition that is a liquid at or below room temperature forms a high viscosity layer or gel at body temperature, which comprises a water-soluble, nonionic cellulose ether having a cloud...
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5492689 |
Combined virustatic antimediator (COVAM) treatment of common colds
The common cold and related disorders such as influenza, acute sinusitis, acute otitis, and infectious exacerbations of obstructive pulmonary disease, are best treated by providing a combination of...
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5489577 |
Semi-solid pharmaceutical agent and process for producing the same
Disclosed is a semi-solid pharmaceutical agent containing a stabilized proteinaceous bioactive substance prepared by successively mixing an oligosaccharide and an aqueous solution of a...
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5487898 |
Compositions and method for the sublingual or buccal administration therapeutic agents
Pharmaceutical compositions for the sublingual or buccal administration of therapeutic agents which are normally degraded upon oral administration comprise such a therapeutic agent, a solvent,...
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5484602 |
Methods and compositions for noninvasive dose-to-effect administration of drugs with cardiovascular or renal vascular activities
The present invention is directed to methods and compositions for noninvasively administering drugs in a dose-to-effect manner to produce a cardiovascular or renal vascular activity. A...
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5472713 |
Therapeutic uses of emu oil
Emu oil is therapeutically used in methods for lowering cholesterol, triglycerides and low density lipoproteins and increasing high density lipoproteins; preventing and treating allergies;...
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5472704 |
Pharmaceutical controlled-release composition with bioadhesive properties
A pharmaceutical composition for the controlled release of medicinal drugs, which has the property of adhering to biologic tissues is described. The characteristic features of the composition are a...
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5468500 |
Soursop flavor
A natural tasting soursop flavoring composition prepared by combining methyl butanoate, methyl 2-butenoate, butanoic acid, methyl hexanoate, methyl 2-hexenoate, hexanoic acid and linalool.
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5455041 |
Method for inducing periodontal tissue regeneration
A method for inducing periodontal regeneration including soft tissue, cementum, and bone regeneration, resulting in a type of healing characteristic of the anatomy and architecture of the...
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5447725 |
Methods for aiding periodontal tissue regeneration
Methods for aiding periodontal tissue regeneration with compositions containing bioresorbable polymers, leachable solvents, and bioavailable drug actives. The compositions useful for these methods...
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5447940 |
Absorbable composite materials for use in the treatment of periodontal disease
Absorbable composite materials are described that comprise a collagen matrix reinforced with a layer of a bioabsorbable polymer. A chemotherapeutic agent is dispersed in the composite material. The...
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5437872 |
Pharmaceutical compositions and a device for administering the same
A pharmaceutical tablet or lozenge is described, which comprises a non-absorbable pharmaceutically active agent, in combination with a tablet matrix, arranged for providing controlled and sustained...
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5425948 |
Pharmaceutical compositions for the treatment and prevention of cutaneous and oral mucous membrane inflammations
The invention relates to pharmaceutical compositions for the treatment and prevention of cutaneous and oral mucous membrane inflammations comprising 18β-glycyrrhetic acid, benezophenanthridine...
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5419915 |
Medicament with an analgesic, antipyretic and/or antiphlogistic action and use of 2-ethoxybenzoic acid
The present invention relates to a medicament with an analgesic, antipyretic and/or antiphlogistic action based on a salicylic acid derivative. The prior art has constantly sought alternatives for...
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5418221 |
Composition containing enamel matrix from tooth germs for inducing binding between living mineralized tissue parts
Binding between parts of living mineralized tissue such as between a tooth and the jaw bone is induced with a composition containing mammalian enamel matrix isolated from tooth germs and a carrier...
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5418220 |
Method for treating constipation using dimethicone
The invention disclosed relates to the use of dimethicone as an agent for treating constipation.
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5414005 |
Methods and articles of manufacture for the treatment of nicotine withdrawal and as an aid in smoking cessation
The present application features methods and articles of manufacture for alleviating acute symptoms of nicotine withdrawal and as an aid in smoking cessation. The invention features lobeline held...
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5413792 |
Mucoadhesive polysiloxane paste-like base and preparation
The specification describes and claims a paste-like preparation comprising (A) a paste-like base comprising a polyorganosiloxane and a water-soluble polymeric material which are preferably present...
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5409905 |
Cure for commond cold
Present invention is a non-toxic, flavor stable, pleasant tasting composition releasing Zn 2 + from compositions containing a highly ionizable zinc compound other than zinc gluconate that reduces...
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5409703 |
Dried hydrogel from hydrophilic-hygroscopic polymer
A therapeutic medical device is described that is comprised of a dried hydrogel of a hydrophilic-hygroscopic polymer, such as an unmodified or modified polymeric carbohydrate, in the form of a...
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5395615 |
Free amine benzophenanthridine alkaloid compositions
A pharmaceutical composition of a free amine benzophenanthridine alkaloid and a pharmaceutically acceptable carrier is disclosed. The composition is an antibacterial and antifungal agent.
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5376386 |
Aerosol carriers
Pharmaceutical excipients useful in dry powder inhalents comprise particles having a rugosity (measured by air permeametry) of less than 1.75. The use of these carriers increases the amount of drug...
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5370864 |
Breath protection microcapsules
The present invention relates to oral compositions in the form of microcapsules which reduce oral bacteria and provide long lasting breath protection.
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5368859 |
Biodegradable system for regenerating the periodontium
Methods are described for assisting the restoration of periodontal tissue in a periodontal pocket and for retarding migration of epithelial cells along the root surface of a tooth. The methods...
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5364634 |
Controlled-release PH sensitive capsule and adhesive system and method
A capsule and method for delivery for an active ingredient in the oral cavity that has a pH sensitive encapsulant shell and is associated with an adhesive. The pH sensitive shell dissolves at a pH...
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5362495 |
Insert material for widening the gingival sulcus
The present invention has for its object an insert material used for widening the gingival sulcus, substantially without bleeding or oozing, particularly in order to make a cast for a dental...
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5362498 |
Process for preparing a bioadhesive pharmaceutical dosage form and pharmaceutical dosage form thus p
The present invention relates to a process for preparing a bioadhesive sustained-release pharmaceutical dosage form, characterized in that: a) at least a part of the active principles is mixed...
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5352448 |
Oral administration of antigens
An oral vaccine formulation is provided for stimulation of an immune response in gut-associated lymphoid tissues. The formulation comprises an enzymatically degradable antigen in a hydrogel matrix....
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5346061 |
Biostable treatment delivery system
A treatment delivery system which uses a flexible plastic outer container and a smaller, readily burstable, thin film plastic inner container fixedly positioned in the outer container. The inner...
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5330762 |
Tandospiaine antidepressive therapy
A dosage form is provided for administering a drug of the formula ##STR1## to a patient to produce an anxiolytic benefit in the patient.
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5328691 |
Fatty acid compositions
A natural or synthetic glycerol oil which comprises at least 20% by weight, preferably at least 25% of di-linoleoyl-mono-gamma-linolenyl-glycerol (DLMG), is used to supplement foods, nutritional...
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5324523 |
Controlled release pharmaceutical preparation and process for preparing same
Controlled release pharmaceutical preparations are prepared by homogenizing an organic or inorganic pharmaceutical active substance such as an opium alkaloid or its salts, an opium antagonist or...
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5324520 |
Intragingival delivery systems for treatment of periodontal disease
A polymeric controlled delivery system is provided for use in treating periodontal disease. The delivery system in a variety of forms is placed directly in the infected gingival tissue where the...
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5298256 |
Desmopressin buccal patch composition
A buccal patch is provided comprised of desmopressin and a matrix of a configuration and size as to fit into the buccal cavity and adhere to the oral mucosa so as to dispense desmopressin through...
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5296228 |
Compositions for controlled delivery of pharmaceutical compounds
Sustained release pharmaceutical compound delivery compositions and methods for their production are disclosed wherein ion exchange resin particles are loaded with releasably bound pharmaceutical...
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5292513 |
Method for nonspecific cellular immune stimulation
A non-specific host defense cell augmentation technique for enhanced microorganism killing utilizes any phagocytosable, biocompatible particle to prime macrophages for enhanced oxidative response...
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5290559 |
Device and method for treatment of infections
A packing material for the treatment of infections, particularly of the teeth and gums. A biocompatible, polymeric carrier material, typically calcium alginate, has dispersed therein an antibiotic...
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5288498 |
Compositions of oral nondissolvable matrixes for transmucosal administration of medicaments
Compositions and methods of manufacture for producing a medicament composition capable of absorption through the mucosal tissues of the mouth, pharynx, and esophagus. The present invention relates...
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