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7615539 Nucleic acid-lipophilic conjugates  
The invention relates to a nucleic acid-lipophilic conjugates and methods for modulating an immune response using the conjugates. The lipophilic moiety associated with an immunostimulatory nucleic...
7615235 Film-shaped or wafer-shaped pharmaceutical preparation with masked taste  
The invention relates to thin film-shaped or wafer-shaped pharmaceutical preparations for oral administration of active substances. The preparations contain at least one matrix-forming polymer...
7601337 Delivery of antipsychotics through an inhalation route  
The present invention relates to the delivery of antipsychotics through an inhalation route. Specifically, it relates to aerosols containing antipsychotics that are used in inhalation therapy. In a...
7596836 Nose and throat anti-influenza solution and method of use  
A nose and throat anti-influenza solution is described that decreases the likelihood influenza infection and its spread. The solution's components are readily available and have been used to treat...
7591999 Powdery preparation for nasal administration  
According to the present invention, a powdery preparation for nasal administration comprising a physiologically active substance, a non-water-absorbing and hardly water-soluble powder(s) and one or...
7585519 Esters of L-carnitine or alkanoyl L-carnitines useful as cationic lipids for the intracellular delivery of pharmacologically active compounds  
Esters of L-carnitine and alkanoyl L-carnitines are described which can be used as cationic lipids for the intracellular delivery of pharmacologically active compounds. New esters of L-carnitine...
7585493 Thin-film drug delivery article and method of use  
An article for use in an aerosol device, for producing an aerosol of a drug composition is disclosed. The article includes a heat-conductive substrate having a surface with a selected surface area,...
7582284 Particulate materials  
The present invention relates to active substances in particulate form, to methods for preparing them, to formulations containing them and to uses of such substances and formulations. A preferred...
7563464 Treatment of mucosal membranes utilizing phytoestrogen  
A composition and method for direct application to mucosal membranes, which combines naturally occurring phytoestrogens, such as plant extracts and soy isoflavones, with other active and inactive...
7553913 Random and non-random alkylene oxide polymer alloy compositions  
A polymeric material comprised of (i) at least one random copolymer comprised of ethylene oxide and one or more other alkylene oxide(s) and (ii) at least one non-random polymer comprised of one or...
RE40812 Nasal calcitonin formulation  
A liquid pharmaceutical composition is disclosed comprising calcitonin or an acid addition salt thereof and citric acid or salt thereof in a concentration from about to about 50 mM, said...
7524828 Immunostimulatory nucleic acid molecules  
Nucleic acid sequences containing unmethylated CpG dinucleotides that modulate an immune response including stimulating a Th1 pattern of immune activation, cytokine production, NK lytic activity,...
7524484 Delivery of diphenhydramine through an inhalation route  
The present invention relates to the delivery of diphenhydramine through an inhalation route. In a composition aspect of the present invention, a composition of a diphenhydramine condensation...
7510702 Delivery of nonsteroidal antiinflammatory drugs through an inhalation route  
The present invention relates to the delivery of nonsteroidal antiinflammatory drugs (NSAIDs) through an inhalation route. Specifically, it relates to aerosols containing NSAIDs that are used in...
7507398 Delivery of physiologically active compounds through an inhalation route  
The present invention relates to the delivery of physiologically active compounds through an inhalation route. Specifically, it relates to aerosols containing physiologically active compounds that...
7498019 Delivery of compounds for the treatment of headache through an inhalation route  
The present invention relates to the delivery of migraine headache drugs through an inhalation route. Specifically, it relates to aerosols containing migraine headache drugs that are used in...
7491047 Delivery of antihistamines through an inhalation route  
The present invention relates to the delivery of antihistamines through an inhalation route. Specifically, it relates to aerosols containing antihistamines that are used in inhalation therapy. In a...
7488469 Delivery of caffeine through an inhalation route  
The present invention relates to the delivery of caffeine through an inhalation route. Specifically, it relates to aerosols containing caffeine that are used in inhalation therapy. In a composition...
7482378 Physiological cooling compositions  
The present invention provides, in one aspect, a physiological cooling composition comprising at least one cyclohexane carboxamide, at least one acyclic carboxamide, and at least one stereoisomer...
7481995 Aerosol composition  
An aerosol composition comprising a propellant and a first particulate material comprising particles having a median aerodynamic diameter with the range 0.05 to 11 μm, such as a medicament...
7476689 Therapeutic compositions for intranasal administration which include KETOROLAC  
An analgesic/anti-inflammatory pharmaceutical dosage form which comprises an effective amount of an active ingredient selected from the group consisting of racemic...
7476659 Liquid composition for bulging mucous membrane for use in endoscopic surgery comprising a chitosan derivative containing carbohydrate chains  
The present invention provides a liquid composition to make the mucous membrane bulge during endoscopic surgery characterized in that it comprises a chitosan derivative containing carbohydrate...
7470422 Method for the production of propellant gas-free aerosols from aqueous medicament preparations  
The present invention relates to pharmaceutical preparations in the form of aqueous solutions for the production of propellant-free aerosols.
7470421 Delivery of diazepam through an inhalation route  
The present invention relates to the delivery of compounds for the treatment of anxiety disorders and symptoms of such disorders through an inhalation route. Specifically, it relates to aerosols...
7468179 Delivery of opioids through an inhalation route  
The present invention relates to the delivery of opioids through an inhalation route. Specifically, it relates to aerosols containing opioids that are used in inhalation therapy. In a method aspect...
7465436 Delivery of compounds for the treatment of Parkinson's through an inhalation route  
The present invention relates to the delivery of antiparkinsons drugs through an inhalation route. In a method aspect of the present invention, an antiparkinsons drug is administered to a patient...
7465435 Delivery of beta-blockers through an inhalation route  
The present invention relates to aerosols containing of atenolol, pindolol, esmolol, propranolol, or metoprolol that are used in inhalation therapy. In a method aspect of the present invention, of...
7452524 Method for improvement of tolerance for therapeutically effective agents delivered by inhalation  
A method for improvement of tolerance for therapeutically effective agents delivered by inhalation comprising a pretreatment of a patient with a nebulized lidocaine or a lidocaine-like compound...
7452523 Targeted delivery of lidocaine and other local anesthetics and a method for treatment of cough and tussive attacks  
An anti-tussive nebulized solution for targeted delivery of lidocaine into conducting and central airways. A method for treatment of cough and tussive attacks or episodes using said lidocaine...
7449174 Delivery of analgesics through an inhalation route  
The present invention relates to the delivery of analgesics through an inhalation route. Specifically, it relates to aerosols containing acetaminophen, orphenadrine or tramadol that are used in...
7449172 Delivery of antiemetics through an inhalation route  
The present invention relates to the delivery of antiemetics through an inhalation route. Specifically, it relates to aerosols containing antiemetics that are used in inhalation therapy. In a...
7445768 Delivery of sedative-hypnotics through an inhalation route  
The present invention relates to the delivery of sedative-hypnotics through an inhalation route. Specifically, it relates to aerosols containing sedative-hypnotics that are used in inhalation...
7442368 Delivery of stimulants through an inhalation route  
The present invention relates to the delivery of stimulants through an inhalation route. Specifically, it relates to aerosols containing stimulants that are used in inhalation therapy. In a method...
7439269 Composition and method for moisturizing nasal tissue  
An improved composition and method for moisturizing a nasal membrane are disclosed. The composition includes a viscous carrier and one or more moisturizing agents disposed with the carrier. The...
7419497 Methods for treating ethmoid disease  
Devices, systems and methods for stenting, spacing, draining, ventilating and/or delivering drugs and other therapeutic or diagnostic substances to desired locations within the bodies of human or...
7399528 Powder particles with smooth surface for use in inhalation therapy  
Carrier particles, for use in the preparation of powdery mixtures for administration by inhalation, and having a median diameter of greater than 90 microns and a surface rugosity expressed as the...
7393544 Dispersion for pulmonary delivery of a bioactive agent  
Stabilized dispersions are provided for the delivery of a bioactive agent. The dispersions preferably comprise a plurality of perforated microstructures dispersed in a suspension medium that...
7393543 Vaginally administratable progesterone-containing tablets and method for preparing same  
The present invention provides a method for preparing a tablet for the vaginal administration of progesterone for systemic use. The method comprises first mixing water with micronized progesterone,...
7384914 Night-time oral insulin therapy  
A method for protection of a mammal that has impaired glucose tolerance or early stage diabetes mellitus from developing overt or insulin dependent diabetes comprises administering an orally...
7381419 Medical composition kit for treating lesioned abnormal tissue  
Optimum compounding composition of a local injection preparation for treating rectal submucous lesioned abnormal tissue with local anesthetic is decided to provide a medical composition kit. In a...
7381402 Stable pharmaceutical solution formulations for pressurized metered dose inhalers  
Aerosol solution formulations for use in an aerosol inhaler which comprise 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-m ethylethyl]amino]-ethyl]-2(1H)-quinolinone or a salt thereof,...
7378082 Method for treating allergic rhinitis without adverse effects  
The present invention is directed to a method for treating allergic rhinitis without causing an adverse effect of bitter taste. The method comprises administering to a patient an aqueous...
7368104 Treatment of respiratory diseases  
A pharmaceutical composition for pulmonary delivery comprises glycopyrrolate in a controlled release formulation, wherein, on administration, the glycopyrrolate exerts its pharmacological effect...
7338665 Methods compositions and devices utilizing stinging cells/capsules for delivering a therapeutic or a cosmetic agent into a tissue  
A delivery device including at least one stinging capsule and methods of use are described.
7332230 Multilayer preparation in film form, consisting of hydrophilic polymers, for the rapid release of active ingredients  
A multilayer preparation in the form of films of hydrophilic polymers for rapid release of substances present in the film layers into liquid surroundings is characterized in that adjacent layers...
RE40045 Medicaments  
Pharmaceutical compositions comprising effective amounts of salmeterol (and a physiologically acceptable salt thereof) and fluctuations propionate as a combined preparation for simultaneous,...
7320800 Vaginally administrable progesterone-containing tablets and method for preparing same  
The present invention provides a method for preparing a tablet for the vaginal administration of progesterone for systemic use. The method comprises first mixing water with micronized progesterone,...
7306812 Dissolvable backing layer for use with a transmucosal delivery device  
A dissolvable backing layer for use with transmucosal drug delivery devices includes a dissolvable hydrophilic region and a non-hydrophilic region that inhibits or slows migration of water, drugs,...
7306787 Engineered particles and methods of use  
Engineered particles are provided may be used for the delivery of a bioactive agent to the respiratory tract of a patient. The particles may be used in the form of dry powders or in the form of...
7294345 Otorhinological delivery device  
The invention relates to an otorhinological delivery device comprising at least one pharmaceutically active agent. According to the invention the device comprises a core comprising said at least...