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6709670 |
Aminoethanesulfonic acid-containing preparations
Preparations to be applied to the oral or nasal cavity which contain aminoethanesulfonic acid and a mucosal stimulant. When these preparations are applied to the oral or nasal cavity,...
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6709669 |
Fast-dispersing dosage forms containing fish gelatin
The invention disclosed herein relates to a pharmaceutical composition comprising a carrier and an active ingredient, wherein the carrier is fish gelatin and the composition is a fast-dispersing...
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6709672 |
Pharmaceutical or food composition for treating pathologies associated with graft rejection or an allergic or autoimmune reaction
The present invention is related to a process for obtaining a composition comprising peptides bound to one or more heat shock protein(s) and for possibly recovering from said composition the bound...
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6703361 |
Method of treating or preventing Type 1 diabetes by oral administration of insulin
Disclosed herein are methods for treating or preventing a disease in mammals having the characteristics of Type 1 diabetes comprising administering insulin or disease suppressive fragments of...
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6699495 |
Methods for treating multiple sclerosis employing desmethylselegiline
Methods and pharmaceutical compositions for using desmethylselegiline. In particular, the present invention provides novel compositions and methods for using desmethylselegiline for...
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6699480 |
Vaccine compositions
The invention provides the use of Hepatitis A virus capsid, or a mucosally immunogenic fragment or epitope thereof, for the manufacture of a mucosal vaccine composition for administration to a...
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6699494 |
Pharmaceutical composition and method for treating premature labor
The present invention teaches a composition comprising a β-adrenergic agonist in a bioadhesive carrier. Preferably, the composition comprises terbutaline in polycarbophil. The present invention...
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6696076 |
Immune response modifier compounds for treatment of TH2 mediated and related diseases
Immune response modifier compounds—imidazoquinoline amines, imidazopyridine amines, 6,7-fused cycloalkylimidazopyridine amines, and 1,2-bridged imidazoquinoline amines—are useful for the...
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6696041 |
Treatment of colds, flu like infections and other general nasal based infections with a solution containing iodine and other broad spectrum microbicides and a method for its use
The invention relates generally to a method which utilizes iodine as a broad spectrum microbicide wherein the active agent may be applied in nasal passages in the manner of a decongestant type nose...
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6685951 |
Administration of dihydroergotamine as a sublingual spray or aerosol for the treatment of migraine
The present invention is an improvement in the treatment of migraine headaches. By administering dihydroergotamine as a sublingual spray or aerosol, major limitations of past treatments are...
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6682757 |
Titratable dosage transdermal delivery system
The present invention relates to a titratable dosage transdermal delivery system for systemic delivery of a therapeutic agent or drug. The system comprises a plurality of patch units that are...
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6676959 |
Nicotine-containing pharmaceutical compositions giving a rapid transmucosal absorption
Formulations of nicotine for use in nicotine replacement therapy. The formulations are intended for application in the oral cavity where upon the uptake of nicotine mainly takes place through the...
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6676958 |
Adjuvant composition for mucosal and injection delivered vaccines
An adjuvant for vaccines comprising lecithin and a polymer, whereby the polymer is preferably polyacrylic acid.
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6677346 |
Methods comprising intranasal morphine
The present invention relates to a pharmaceutical formulation for intranasal administration comprising morphine or pharmaceutically acceptable salt thereof at a pH from about 3.0 to about 7.0. Such...
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6663873 |
Antigenic preparation for treatment or prevention of helicobacter infection
An antigenic preparation for use in the treatment or prevention of Helicobacter infection in a mammalian host, comprises the lipopolysaccharide (LPS) of Helicobacter bacteria, particularly the LPS...
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6663883 |
Matrix adhering to nasal mucosa
This invention provides a matrix adhering to the nasal mucosa which allows improved transfer into the brain of a drug exerting its effect in the brain and is capable of continuously supplying the...
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6652885 |
Purification and stabilization of peptide and protein pharmaceutical agents
Methods are provided for purifying peptides and proteins by incorporating the peptide or protein into a diketopiperazine or competitive complexing agent to facilitate removal one or more...
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6649145 |
Compositions and method of tissue superoxygenation
Disclosed are methods and compositions for increasing tissue oxygen levels by administration of superoxygenated compositions of tissue surfaces. The methods are applicable to treatment of a wide...
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6649183 |
Methods for treating apnea and apnea disorders using optically pure R(&plus ) ondansetron
Methods for the treatment, management, or prevention of apnea and apnea disorders, or symptoms thereof, using a therapeutically effective amount of substantially optically pure R(+) ondansetron, or...
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6641799 |
Nasal spray for decongesting nasal passages
A therapeutic composition for use as a nasal spray the aids in decongesting of the nasal passages by osmotic effect, thinning of mucus and stimulation of ciliary function. Preferred embodiments of...
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6641801 |
Gargle method to reduce the duration of common cold symptoms
The common cold is caused by a virus. Antiviral compounds that kill viruses would then be most likely to serve as a remedy for the common cold. This invention seeks to offer a unique use of an...
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6642275 |
Formulation for respiratory tract administration
A dosage form for intranasal and/or inhalation administration of an analgesic having low opioid receptor binding activity to a warm blooded animal, that includes a pharmaceutically effective amount...
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6638521 |
Oral liquid mucoadhesive compositions
The present invention relates to a per oral, oral, or intranasal pharmaceutical mucoretentive, aqueous liquid composition comprising from about 2% to about 50%, by weight of the composition, of...
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6635272 |
Wound dressing and drug delivery system
A dressing and method of treating wounds is provided. The dressing can comprise water-soluble or swellable polymers capable of forming viscous aqueous or non-aqueous solution and form a gel, and...
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6635263 |
Beauty method
The present invention relates to a beauty method in which a sound skin condition can be maintained or created and/or deep relaxation can be appreciated, wherein a comfort-stimulating means capable...
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6632447 |
Method for chemoprevention of prostate cancer
This invention relates to the chemoprevention of prostate cancer and, more particularly, to a method of suppressing or inhibiting latent prostate cancer comprising administering to a mammalian...
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6632440 |
Methods and compounds for the treatment of mucus hypersecretion
A method of treating mucus hypersecretion, the causative factor in chronic obstructive pulmonary disease (COPD), asthma and other clinical conditions involving COPD, comprises administering a...
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6632419 |
Increasing libido in humans via acute testosterone administration
The libido of adult human female patients is increased by the bolus delivery of a testosterone which is preferably dihydrotestosterone. The formulation is preferably aerosolized and inhaled into a...
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6630169 |
Particulate delivery systems and methods of use
Compositions and methods are provided for the administration of particulates comprising at least one bioactive agent which, in selected embodiments, may comprise and immunoactive agent. In this...
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6627211 |
Transnasal anticonvulsive compositions and modulated process
A method of vehicle modulated administration of an anticonvulsive agent to the nasal mucous membranes of humans and animals is disclosed. The vehicle system is an aqueous pharmaceutical carrier...
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6623760 |
Method of preparing particles for agglomeration
Methods of preparing particulates for agglomeration, having a specified particle size distribution and desired convertible amorphous content, are described. The method involves a plurality of...
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6623732 |
Pharmaceutical formulation for nasal administration
This invention discloses a pharmaceutical formulation for nasal administration which contains a pharmaceutically active polypeptide and a method producing the pharmaceutical formulation. The...
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6616944 |
Self-assembling colloidal carriers for protein delivery
The invention is directed to self-assembling, polymer-based delivery systems for proteins. The delivery systems comprises an active agent and a polyol ester of the invention, having a linear polyol...
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6613344 |
Methods utilizing stinging cells/capsules
A composition of matter including a therapeutic or a cosmetic agent and at least one stinging capsule and methods of use are described.
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6613358 |
Sustained-release composition including amorphous polymer
Provided is a sustained release composition for sustained release of a pharmaceutical substance. The composition includes a biocompatible polymer that is highly amorphous and a pharmaceutical...
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6613345 |
Conjugates of sodium channel blockers and methods of using the same
Compounds of the general formula P 1 -L-P 2 ; wherein “P 1 ” is a pyrazinoylguanidine sodium channel blocker, “L” is a linking group, and “P 2 ” is either (i) a pyrazinoylguanidine...
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6610324 |
Flupirtine in the treatment of fibromyalgia and related conditions
The present invention is directed to a method for treating the symptoms associated with fibromyalgia and related conditions by administering flupirtine.
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6610310 |
Polyanionic polymers as adjuvants for mucosal immunization
Mucosal adjuvants for vaccines contain water-soluble polyanionic polymers which have anionic constitutional units obtained from acids such as acrylic acid, methacrylic acid, maleic acid, fumaric...
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6607742 |
Suppository composition which is a spray-dried suspension of an acid-labile proton pump inhibitor in a solvent solution of a sterol and polymer
Acid-labile active compounds are prepared in suppository form, particularly for rectal administration.
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6608073 |
Intranasal codeine for the rapid suppression of cough and rapid relief of pain
This invention provides a method of rapidly and reliably delivering codeine, alone or in combination with other compounds, to the systemic circulation by administration via the nasal route to...
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6602519 |
Oxidized thymosin β4
The present invention relates to the use of oxidized thymosin β4 in therapy, more particularly in the treatment of diseases or conditions associated with an inflammatory response of septic shock.
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6596297 |
Biodegradable microbicidal vaginal barrier device
An intravaginal bio-erodible microbicidal barrier device. The device comprises (a) at least one micronized compound selected from the group consisting of cellulose acetate phthalate and...
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6596740 |
Nicotine mucosal spray
A composition for administration to the nasal mucosa of a subject comprises a solution of nicotine or a pharmaceutically acceptable salt thereof in a pharmaceutically acceptable solvent. The...
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6596295 |
Aqueous solution for treating degenerative or autoimmune diseases and/or as an immunomodulatory agent
The invention concerns an aqueous solution capable of being injected by perinodular delivery or inhaled for use in the treatment of degenerative or autoimmune diseases or as immunomodulatory agent....
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6592887 |
Water soluble film for oral administration with instant wettability
A composition containing therapeutic agents and/or breath freshening agents for use in the oral cavity is disclosed. The carrier comprises water-soluble polymers in combination with certain...
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6592860 |
Composition and applicator for topical substance delivery
A polymerized hydrogel composition and applicator for hydrating or dehydrating a surface, particularly a dermatological surface, to which it is applied and a method for forming the composition. The...
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6592899 |
PLA/PLGA oligomers combined with block copolymers for enhancing solubility of a drug in water
Polymeric compositions having improved capability of solubilizing a drug in a hydrophilic environment to form a solution, comprising: a biodegradable polyester oligomer; and biodegradable AB-type,...
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6592894 |
Hydrogel-isolated cochleate formulations, process of preparation and their use for the delivery of biologically relevant molecules
A process for producing a small-sized, lipid-based cochleate. Cochleates are derived from liposomes which are suspended in an aqueous two-phase polymer solution, enabling the differential...
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6592903 |
Nanoparticulate dispersions comprising a synergistic combination of a polymeric surface stabilizer and dioctyl sodium sulfosuccinate
Disclosed are solid dose nanoparticulate compositions comprising a poorly soluble active agent, at least one polymeric surface stabilizer, and dioctyl sodium sulfosuccinate (DOSS). The solid dose...
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6589560 |
Stable glassy state powder formulations
A powdered, dispersible composition having stable dispersibility over time is provided. The composition exhibits a characteristic glass transition temperature (T g ) and a recommended storage...
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