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5015474 |
Composition for imparting moisture to a substrate
Methods and compositions are provided for alleviating the dryness of a dermal or mucosal membrane substrate. The compositions are formulated from eriodictyon fluid which is a Yerba Santa extract...
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5015631 |
Repairing agent for cells and tissues
A repairing agent for cells and tissues is disclosed, which agent comprises, as an active ingredient, a compound of the general formula: ##STR1## wherein Z represents lithium, potassium, sodium,...
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5013552 |
Modified pollen grains for delivering biologically active substances to plants and animals
Loaded pollen grains are disclosed which are suitable for use as delivery systems for introducing biologically active substances into or on plants and animals. Such pollen grains are suitable to...
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4996056 |
Dental floss and tape
Fluorocarbon polymer powder particles, e.g. particulate PTFE, are included, as a solid lubricant, in the binder applied to dental floss or tape.
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4988512 |
Nasal pharmaceutical compositions
Solid nasal inserts of calcitonin and other peptides have particularly interesting drug absorption profiles.
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4983398 |
Sustained release drug dosage forms containing hydroxypropylmethylcellulose and alkali metal carboxylates
A therapeutically active solid unit dosage form comprising a carrier base material combined with a therapeutically active medicament and shaped and compressed to a solid unit dosage form having a...
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4983395 |
Device for administering an active agent to the skin or mucosa
A transdermal drug delivery device comprising a drug formulation-containing reservoir defined by a backing layer and a drug-permeable membrane layer, a peelable inner liner that underlies the...
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4981694 |
Penicillin preparation for rectal administration
Penicillin preparation for rectal administration containing benzylpenicillin and sodium lauryl sulphate in a hard gelatin capsule.
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4971790 |
Dosage form for lessening irritation of mocusa
A composition of matter comprising a drug, a neutral hydrogel and an ionic hydrogel. The composition can be administered from a delivery system to a biological receptor over time.
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4968633 |
Mucosal allergo-test and relevant device for the determination of specific and total IgE
An allergological test for detecting an allergic condition, said test consisting in contacting the mucous membrane direct with the allergen or the anti-IgE antibody linked to a solid phase, so that...
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4954342 |
Pharmaceutical composition for intrarectal administration of a calcitonin and unit dosage forms prepared therefrom
New compositions containing a calcitonin as the active ingredient are described which are suitable for the intrarectal administration as soft gelatin capsules or microenemas, wherein the active...
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4948588 |
Percutaneous absorption accelerator and preparation containing same
A percutaneous absorption accelerator and a percutaneous absorbent preparation containing the same and, more particularly, a percutaneous absorption accelerator containing either derivatives of...
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4948587 |
Ultrasound enhancement of transbuccal drug delivery
A method using ultrasound for enhancing and controlling transbuccal permeation of a molecule, including drugs, antigens, vitamins, inorganic and organic compounds, and various combinations of these...
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4948580 |
Muco-bioadhesive composition
A bioadhesive composition is provided which may be employed as an oral drug delivery system and includes a freeze-dried polymer mixture formed of the copolymer poly(methyl vinyl ether/maleic...
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4940587 |
Oral pharmaceutical composition through mucosa
An arrangement is provided for the application of an oral pharmaceutical to the mucosa of the oral or nasal cavity, for sustained release there of the drug. The arrangement of the invention...
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4891226 |
Pharmaceutical which can be administered nasally, a process for its preparation, and its use
A pharmaceutical which is for nasal administration and contains a high molecular weight active compound and a gel-forming agent and, where appropriate, auxiliaries is described. High molecular...
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4883660 |
Gel bases for pharmaceutical compositions
Gel bases for pharmaceutical compositions comprise from about 0.5 to about 10.0% by weight ethoxylated (2 to 30 moles of ethoxylation) behenyl alcohol and from about 90 to 99.5% of a glycol solvent...
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4876092 |
Sheet-shaped adhesive preparation applicable to oral cavity
A sheet-shaped adhesive preparation comprising an adhesive layer containing as essential components a carboxyvinyl polymer, a water-insoluble methacrylic copolymer, a polyhydric alcohol and a...
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4867969 |
Hydrogel formulation for administering non-steroidal drugs
A composition of matter comprising a drug, a neutral hydrogel and an ionic hydrogel. The composition can be administered from a delivery system to a biological receptor over time.
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4855142 |
Pharmaceutical plaster
The invention relates to a pharmaceutical plaster that adheres to the mucosa, consisting of two discrete layers that adhere well to one another, which may contain pharmaceutical active ingredients...
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4842862 |
Immunostimulating agents
The Resorcylic Acid Lactone (RAL) derivatives zearalenone, zearalanone, zearalene, zearalane, zearalenol, zearalanol, and dideoxyzearalane are administered to vertebrates to non-specifically...
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4767612 |
Triamcinolone acetonide for the treatment of allergic rhinitis
Disclosed is a method for the treatment of allergic rhinitis that manifests itself as rhinorrhea, nasal itching, sneezing, congestion and postnasal drip. The method comprises the administration...
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4765983 |
Adhesive medical tapes for oral mucosa
Adhesive medical tapes for oral mucosa comprising a support layer composed of an intestine-soluble polymer and a medicament-containing layer composed of a water-soluble polymer containing at least...
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4756710 |
pH-Mediated drug delivery system
A method and device for delivering acidic or basic drugs in a controlled delivery system is described.
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4740365 |
Sustained-release preparation applicable to mucous membrane in oral cavity
A sustained-release preparation applicable to mucous membrane in oral cavity which comprises an active ingredient and a mixture of a polymer component (A) comprising one or more polymers selected...
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4609374 |
Osmotic device comprising means for governing initial time of agent release therefrom
An osmotic dispensing device is disclosed for delivering a medicine to a biological environment of use. The device comprises a semipermeable wall surrounding a compartment with an osmotic...
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4573996 |
Device for the administration of an active agent to the skin or mucosa
A device is disclosed for administration of an active agent to a host, e.g., for transdermal administration. The device includes an impermeable adhesive layer which surrounds the permeable adhesive...
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4559054 |
Rate-controlled drug release system
A drug release device employing a block copolymer of poly(ether-urethane)/poly(dimethyl siloxane) is useful for dispensing lipophilic drugs at a high controlled rate for prolonged periods of time....
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4457756 |
Nose bleed clip
A device for treatment of nose bleed, the invention in a preferred embodiment takes the form of a bifurcated clip having opposed legs connected by a bight portion to gently urge the distal ends of...
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4449983 |
Simultaneous delivery of two drugs from unit delivery device
An osmotic device is disclosed for delivering two beneficial drugs to an environment of use. The device comprises a wall surrounding a lumen divided into a first compartment containing a drug that...
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4394390 |
Nasal dosage forms of propranol
The invention relates to a novel method of administering propranolol, a known β-adrenergic blocking agent widely used in the treatment of angina pectoris, arrhythmias, hypertension and other...
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4369783 |
Device for the prophylactic or therapeutic treatment of cattle
Nose-clip for the prophylactic or therapeutic treatment of cattle, which comprises a bow whose ends are suitable for receiving active ingredients in the form of depot bodies, the receiving ends...
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4331651 |
Depot body on the basis of silicone rubber and process for the preparation thereof
Depot body on the basis of silicone rubber for the protracting release of active ingredients which contains from 2 to 50 weight %, relative to silicone rubber, of a release-promoting substance or a...
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4325967 |
Cyclopentane derivatives
Cyclopentane derivatives of the formula: ##STR1## wherein R 1 represents hydrogen or a carboxylic acyl group, and either (i) R 2 represents a group of the formula: --CR 3 R 4 R 5 ...
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4322323 |
Erodible device comprising surfactant for modifying the rate of erosion of the device
An erodible device is disclosed for delivering an agent to an environment of use. The device comprises (1) a structure sized and adapted for placement in an environment of use, the structure...
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4320759 |
Dispenser with diffuser
A system is disclosed for delivering a beneficial agent at a substantially constant rate over time. The system comprises (1) a wall formed of a microporous polymer, or (2) a wall formed in part of...
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4309996 |
System with microporous releasing diffusor
A system is disclosed for delivering a beneficial agent at a substantially constant rate over time. The system comprises (1) a wall formed of a microporous polymer, or (2) a wall formed in part of...
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4292299 |
Slow-releasing medical preparation to be administered by adhering to a wet mucous surface
PCT No. PCT/JP79/00284 Sec. 371 Date Nov. 6, 1979 Sec. 102(e) Date July 7, 1980 PCT Filed July 7, 1980 PCT Pub. No. WO80/00916 PCT Pub. Date May 15, 1980 A medical preparation composed of an...
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4235236 |
Device for dispensing drug by combined diffusional and osmotic operations
A device is disclosed for delivering an agent to an environment of use at a substantially constant rate over time. The device comprises a wall formed of a microporous material surrounding a...
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4203439 |
Osmotic system with volume amplifier for increasing amount of agent delivered therefrom
An osmotic system for delivering a beneficial agent is disclosed. The system comprises a wall surrounding a compartment and has a passageway through the wall for delivering agent from the...
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4160452 |
Osmotic system having laminated wall comprising semipermeable lamina and microporous lamina
An osmotic therapeutic system for delivering a beneficial drug is disclosed. The system comprises a drug delivery module which module comprises a rate controlling laminated wall surrounding a...
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3996934 |
Medical bandage
A bandage for continuously administering controlled quantities of systemically active drugs through the skin or mucosa is disclosed. This bandage has a backing member which defines one of its face...
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3993072 |
Microporous drug delivery device
A drug delivery device for administering a drug at a controlled rate for a prolonged period of time to produce a local or systemic physiological or pharmacological effect is comprised of a wall...
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3865108 |
EXPANDABLE DRUG DELIVERY DEVICE
A drug delivery device having a drug containing zone associated with and partially defined by a material which swells on contact with body fluids. When swelling occurs, the pressure on the drug...
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3797494 |
BANDAGE FOR THE ADMINISTRATION OF DRUG BY CONTROLLED METERING THROUGH MICROPOROUS MATERIALS
A bandage for use in the continuous administration of drugs to the skin or mucosa, comprising a backing member defining one exterior surface, a surface of pressure-sensitive adhesive defining a...
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3742951 |
BANDAGE FOR CONTROLLED RELEASE OF VASODILATORS
Medical bandage for use in the continuous administration to circulation of controlled quantities of systemically active coronary vasodilators over a prolonged period of time by absorption through...
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3731683 |
BANDAGE FOR THE CONTROLLED METERING OF TOPICAL DRUGS TO THE SKIN
Bandage for the topical administration of controlled therapeutically effective quantities of topically active drugs has a backing member, a pressure-sensitive adhesive, and a reservoir layer...
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3551556 |
CARRIERS FOR BIOLOGICALLY ACTIVE SUBSTANCES
Drugs are released gradually to a living organism after oral ingestion, through a layer of non-ionogenic, neutral hydrogel of a polymer of ethylene glycol methacrylate or similar monomer...
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3518340 |
METHOD OF FORMING SILICONE RUBBER DRUG CARRIERS
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2975099 |
Polyethylene glycol suppository bases
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