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5648089 |
Extract solution and herbal mixture for treatment of hepatitis
A newly formulated herbal mixture and herbal nasal drops are provided for ethical use and treatment of vital hepatitis diseases. The herbal formulation is in two parts, which may be used separately...
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5645827 |
Muco-adhesive polymers
Compositions comprising cationic polysaccharide polymers and anionic therapeutic agents which can have enhanced substantivity to mucosal surfaces are disclosed. These compositions are well suited,...
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5643582 |
Moisturizer
This invention is a long acting moisturizer particularly suited for moisturizing the epithelia.
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5643603 |
Composition of a bioadhesive sustained delivery carrier for drug administration
A composition of a bioadhesive carrier for a prolonged, sustained and controlled delivery of a drug having a local or systemic action contains pregelatinized or thermally modified, food accepted...
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5639795 |
Liquid polymer composition, and method of use
The invention relates to methods for the treatment of gingivitis, oral plaque and oral or dermatological fungal infections by the administration of a liquid methacrylic acid copolymer composition...
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5637314 |
Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis
A method for treating atopic dermatitis, hayfever, asthma and pruritis that includes topical or systemic application of an effective amount of buspirone or a buspirone derivative or its...
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5637311 |
Zinc(II) complexes and methods related thereto
Zinc(II) complexes and methods relating thereto are disclosed. The zinc(II) complexes comprise a zinc(II) ion complexed by a multi-dentate ligand. Methods of this invention include the use of the...
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5635520 |
Anti-ulcer compositions suitable for rectal administration
The present invention relates to a composition for rectal administration which comprises a benzimidazole compound having antiulcer activity and a salt of C 6 -20 fatty acid, both of which are...
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5633003 |
Use of intratracheally administered hyaluronic acid to ameliorate emphysema
The subject invention is directed to the treatment of respiratory disorders by intratracheal administration of an effective amount of hyaluronic acid. Respiratory disorders include emphysema,...
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5631017 |
Topical application of buspirone for treatment of pathological conditions associated with immune responses
A method for the treatment of a cutaneous, ocular, or mucosal pathological condition which is associated with an immune response in a human or other mammal, that includes topical application of an...
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5629011 |
Composition for nasal administration
A composition for nasal administration of polar metabolites of opioid analgesics comprises a polar metabolite of an opioid analgesic and an absorption promoting agent. Preferred metabolites...
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5620699 |
Method for delivering nonaqueous fluorinated drug delivery vehicle suspensions
Nonaqueous pharmaceutical compositions for use in aqueous physiological systems are disclosed comprising drug delivery vehicles suspended in nonaqueous perfluorocarbon or fluorinated silicone...
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5618550 |
Method for treatment of abnormal conditions of the epithelium of bodily orifices
A stable solution, cream, salve, or spray composition containing activated stabilized chlorine dioxide and phosphates, such as disodium hydrogen phosphate, sodium dihydrogen phosphate, trisodium...
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5618554 |
Inhibition of exoprotein using amine compositions in absorbent article and method thereof
Absorbent articles, such as catamenial tampons, for absorbing body fluids have included an effective amount of a nitrogen containing compound to substantially inhibit the production of exotoxins by...
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5607662 |
Pharmaceutical inhalation compositions
A non-pressurized pharmaceutical inhalation composition includes a therapeutically effective amount of a particulate inhalation medicament. The medicament has a mass median diameter in the range...
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5599554 |
Treatment of nicotine craving and/or smoking withdrawal symptoms
The subject invention encompasses a transdermally or transmucosally administrable composition for the treatment or nicotine craving or smoking withdrawal symptoms comprising nicotine and caffeine...
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5595753 |
Topical formulations and methods for treating hemorrhoidal pain and sphincter and smooth muscle spasm in the gastrointestinal tract
A topical treatment for hemorrhoidal pain and for spasms of the sphincters and muscles located in the gastrointestinal (GI) tract is disclosed. The topical preparation includes the amino acid...
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5591441 |
Composition for nonspecific cellular immune stimulation
A non-specific host immune cell augmentation composition for enhanced microorganism killing utilizes any phagocytosable, biocompatible particle to prime macrophages for enhanced oxidative response...
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5585108 |
Formulations of oral gastrointestinal therapeutic agents in combination with pharmaceutically acceptable clays
Nanoparticulate crystalline therapeutic substances formulated with stabilizers and pharmaceutically acceptable clays to enhance contact between the crystalline therapeutic substances and the...
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5578315 |
Mucosal adhesive device for long-acting delivery of pharmaceutical combinations in oral cavity
Mucosal adhesive devices are provided for use in the oral cavity for therapy against infections. The devices are dosage units which comprise a combination of antimicrobial agents such as antifungal...
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5578310 |
Topical bioadhesive ointment compositions and their use in wound healing
A topical bioadhesive ointment composition comprising an aqueous mineral oil emulsion which is readily spread able and film-forming, and, upon application to moist skin or a mucosal surface, forms...
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5573776 |
Oral osmotic device with hydrogel driving member
An osmotic device (10) for delivering an ergot alkaloid into the mouth of a human patient is disclosed. The device (10) has a size and shape adapting it to be comfortably retained in the mouth for...
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5571524 |
Agent for curing ischemic myocardial disease
An agent for curing ischemic myocardial disease which contains an effective amount of diadenosine 5',5'"-p 1 ,p 4 -tetraphosphate (Ap4A) of formula (I): ##STR1## or a pharmaceutically-acceptable...
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5571526 |
Composite metal hydroxide and its use
A composite metal hydroxide which is a solid solution of the formula (1), Mg 1 -x M 2 + x (OH) 2 (1) wherein M 2 + is at least one divalent metal ion selected from the...
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5562908 |
Treatment of sinus headache
The present invention contemplates nasal compositions effective for relieving mammalian sinus headache associated with inflamed or congested turbinates, or both, accompanied by localized pain...
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5554378 |
Pharmaceutical composition and its mucosal use
A pharmaceutical composition containing a physiologically active peptide or protein which is poorly absorbable through the gastrointestinal tract and heat-labile enterotoxin B subunit brings an...
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5554388 |
Systemic drug delivery compositions comprising a polycationi substance
A composition for administration to the mucosa comprises a pharmacologically active compound and a polycationic substance. The polycationic substance is preferably DEAE-dextran or chitosan and the...
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5540931 |
Methods for inducing site-specific immunosuppression and compositions of site specific immunosuppressants
The present invention provides methods and formulations for site-specific immune suppression of immune/inflammatory responses with localized or topical application of immunosuppressants including...
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5540930 |
Suspension of loteprednol etabonate for ear, eye, or nose treatment
The invention provides novel compositions of matter containing water-insoluble steroid drugs suitable for therapeutic use. The invention provides stable aqueous suspensions of water-insoluble...
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5538738 |
Retard systems for the sustained release of medicinal and/or biological valuable materials from a depot carrier material
The invention relates to the use of free radical-reactive cross-linker components based on olefinically unsaturated esters of lower hydroxycarboxylic acids and/or oligomers thereof for modifying...
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5536506 |
Use of piperine to increase the bioavailability of nutritional compounds
A new composition and method for the improvement of gastrointestinal absorption and systemic utilization of nutrients and nutritional supplements, wherein the composition comprises an extract from...
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5534496 |
Methods and compositions to enhance epithelial drug transport
Methods and compositions provided for enhancing the transport of drugs (including peptides, oligonucleotides, proteins and conventional drugs) across epithelial cells at mucosal sites. The methods...
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5518731 |
Nonaqueous fluorinated drug delivery vehicle suspensions
Nonaqueous pharmaceutical compositions for use in aqueous physiological systems are disclosed comprising drug delivery vehicles suspended in nonaqueous perfluorocarbon or fluorinated silicone...
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5518730 |
Biodegradable controlled release flash flow melt-spun delivery system
Biodegradable controlled release delivery systems using melt-spun biodegradable polymers as carriers for bio-effecting agents such as pharmaceutical actives are disclosed. Oral dosage forms as well...
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5516523 |
Transmucosal delivery of macromolecular drugs
A method and system for mucosally administering a macromolecular drug to mucosa of the oral cavity is shown. The system comprises an inner drug/enhancer/polymer layer having one surface adapted to...
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5514673 |
Pharmaceutical composition containing lipophilic drugs
A pharmaceutical composition having a form suitable for transmucosal administration containing progesterone and/or 17-β-estradiol as an active ingredient.
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5512290 |
Compositions containing 2-acetyl-1-pyrroline
A powder-form composition of 2-acetyl-1-pyrroline incorporated with a support of maltodextrin and/or cyclodextrin. The composition is prepared by hydrolyzing a 2-(1-alkoxyethenyl)-1-pyrroline with...
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5492937 |
Gel-forming liquid carrier composition
A carrier composition that is a liquid at or below room temperature forms a high viscosity layer or gel at body temperature, which comprises a water-soluble, nonionic cellulose ether having a cloud...
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5492689 |
Combined virustatic antimediator (COVAM) treatment of common colds
The common cold and related disorders such as influenza, acute sinusitis, acute otitis, and infectious exacerbations of obstructive pulmonary disease, are best treated by providing a combination of...
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5489435 |
Composition for treatment of abnormal conditions of the epithelium of bodily orifices
A stable solution, cream, salve, or spray composition containing activated stabilized chlorine dioxide and phosphates, such as disodium hydrogen phosphate, sodium dihydrogen phosphate, trisodium...
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5489577 |
Semi-solid pharmaceutical agent and process for producing the same
Disclosed is a semi-solid pharmaceutical agent containing a stabilized proteinaceous bioactive substance prepared by successively mixing an oligosaccharide and an aqueous solution of a...
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5487898 |
Compositions and method for the sublingual or buccal administration therapeutic agents
Pharmaceutical compositions for the sublingual or buccal administration of therapeutic agents which are normally degraded upon oral administration comprise such a therapeutic agent, a solvent,...
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5484602 |
Methods and compositions for noninvasive dose-to-effect administration of drugs with cardiovascular or renal vascular activities
The present invention is directed to methods and compositions for noninvasively administering drugs in a dose-to-effect manner to produce a cardiovascular or renal vascular activity. A...
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5472713 |
Therapeutic uses of emu oil
Emu oil is therapeutically used in methods for lowering cholesterol, triglycerides and low density lipoproteins and increasing high density lipoproteins; preventing and treating allergies;...
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5466464 |
Intrabuccally disintegrating preparation and production thereof
A solid preparation soluble in the buccal cavity, which is composed of a sugar comprising lactose and/or mannitol and 0.1-1.2 w/w%, based on the sugar, of agar and an active ingredient and has a...
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5447725 |
Methods for aiding periodontal tissue regeneration
Methods for aiding periodontal tissue regeneration with compositions containing bioresorbable polymers, leachable solvents, and bioavailable drug actives. The compositions useful for these methods...
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5436009 |
Sustained release suppositories and a process for preparation
A sustained release suppository comprising in a usual suppository base a) a water-soluble therapeutically active substance, the average particle size of which is smaller than 20 μm, b) a...
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5433958 |
Pharmaceutical dosage unit for rectal administration
A pharmaceutical dosage unit defined by a sheath composed of a bioadhesive material which surrounds one or more capsules and one or more nonliquid supports containing the active pharmaceutical...
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5427797 |
Systemic effects of nitric oxide inhalation
Nitric oxide or nitric oxide releasing or delivering compounds administered by the inhalation route to humans and animals in need thereof have a systemic and pulmonary effect of preventing or...
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5425948 |
Pharmaceutical compositions for the treatment and prevention of cutaneous and oral mucous membrane inflammations
The invention relates to pharmaceutical compositions for the treatment and prevention of cutaneous and oral mucous membrane inflammations comprising 18β-glycyrrhetic acid, benezophenanthridine...
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