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7521064 |
Non-hormonal vaginal contraceptive
The present invention relates to a non-hormonal, biocompatible, and biodegradable intravaginal device for the delivery of spermiostatic, spermicidal and anti-infectious agents. The present...
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7438836 |
Dispersion and coating preparation containing nanoscale zinc oxide
The present invention provides a dispersion, which contains nano-sized zinc oxide particles, a coating preparation containing the dispersion, a process for the production of the dispersion, and a...
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7262164 |
Polymeric thiol-linked prodrugs employing benzyl elimination systems
Thiol-linked polymeric prodrugs, methods of making and using the same are disclosed. The use of a sulfhydryl bond in combination with a benzyl elimination system results in the formation of...
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7041310 |
Pharmaceutical preparation for the treatment of gynecological diseases
This invention provides to a novel pharmaceutical preparation for the treatment of gynecological diseases. The pharmaceutical preparation according to the invention comprises a therapeutic drug for...
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7005138 |
Method of systematically delivering SSRIs
Methods and compositions are disclosed for the intravaginal or rectal delivery of selected serotonin reuptake inhibitors (SSRIs) to the systemic circulation. Such methods and compositions are...
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6951654 |
Intravaginal drug delivery devices for the administration of an antimicrobial agent
An intravaginal antimicrobial drug delivery device is disclosed having an antimicrobial agent dispersed throughout a biocompatible elastomeric system. Also disclosed is a method of making the...
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6899890 |
Bioadhesive drug delivery system
The present invention relates to a novel essentially pH neutral vaginal drug delivery system suitable for modified delivery of a therapeutically active material in the vaginal cavity. The vaginal...
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6646144 |
Dimethicone copolyol cranberriate as a delivery system for natural antioxidants
The present invention relates to cranberry seed oil derivatives derived by the reaction of dimethicone copolyol and cold pressed cranberry seed oil. The choice of cold pressed cranberry seed oil as...
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6596297 |
Biodegradable microbicidal vaginal barrier device
An intravaginal bio-erodible microbicidal barrier device. The device comprises (a) at least one micronized compound selected from the group consisting of cellulose acetate phthalate and...
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6592894 |
Hydrogel-isolated cochleate formulations, process of preparation and their use for the delivery of biologically relevant molecules
A process for producing a small-sized, lipid-based cochleate. Cochleates are derived from liposomes which are suspended in an aqueous two-phase polymer solution, enabling the differential...
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6544546 |
Ring-shaped devices
A ring-shaped device for controlled release of hormonal compounds comprising a first compartment having a non-medicated core of ethylene-vinyl-acetate copolymer encircled by a steroid hormone...
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6537566 |
Compositions and methods for the non-invasive treatment of uterine fibroid cells
The proliferation of uterine fibroid leiomyoma cells is inhibited by certain Fibroid Cell Growth Inhibitor (FGI) agents. The pharmacological doses of these FGI agents in the milieu of uterine...
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6455034 |
Method for inhibiting the development of body odors
Methods, compositions and products are described which inhibit the development of odor in excreted body fluids by odor-causing cations.
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6436428 |
Device and method for treating urinary incontinence in females
Provided herein is a novel and useful device and method for locally delivering and controllably releasing oxybutynin in the cervical region of a female. A device of the invention comprises a ring...
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6420336 |
Methods of using cyanovirins topically to inhibit viral infection
The present invention provides antiviral proteins, peptides and conjugates, as well as methods of obtaining these agents. The antiviral proteins, peptides and conjugates of the present invention...
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6416780 |
Intravaginal drug delivery devices for the administration of testosterone and testosterone precursors
This invention relates to an intravaginal shell or core drug delivery device suitable for administration to female humans or animals comprises testosterone or a testosterone precursor in a polymer...
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6416779 |
Device and method for intravaginal or transvaginal treatment of fungal, bacterial, viral or parasitic infections
Devices, methods, and compositions for treating vaginal fungal, bacterial, viral and parasitic infections by intravaginal or transvaginal administration of therapeutic and/or palliative antifungal,...
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6361780 |
Microporous drug delivery system
A drug delivery device is described comprising a porous biocompatible solid having at least one therapeutic drug within its pores, the therapeutic drug being removable from the pores by immersion...
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6294188 |
Methods involving changing the constitutive and stimulated secretions of the local reproductive system of women
The first aspect of the invention relates to a method of inducing changes in the cervical mucus of a person to achieve a contraceptive effect, and wherein the method involves administering to the...
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6264973 |
Apparatus and method for anesthetizing the cervical region of a female
A novel and useful apparatus for delivering an anesthetic locally to the cervical region of a female is provided, wherein the apparatus comprises a ring having a surface and at least one depression...
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6197327 |
Device and method for treatment of dysmenorrhea
Methods, devices, and compositions for treatment of dysmenorrhea comprise an intravaginal drug delivery system containing an appropriate pharmaceutical agent incorporated into a pharmaceutically...
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6165493 |
"Methods and compositions for decreasing the frequency of HIV, herpesvirus and sexually transmitted bacterial infections"
A method for decreasing the frequency of transmission of human immunodeficiency virus or herpesviruses or for preventing the transmission of or treating a sexually transmitted bacterial infection...
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6126958 |
Intravaginal rings with insertable drug-containing core
Disclosed is a vaginal ring intended for the release of at least one drug over a prolonged time period. The vaginal ring contains a ring body made of a first polymeric material having at least one...
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6103256 |
Intravaginal drug delivery device
An intravaginal drug delivery device comprising at least one active agent dispersed in a polymer matrix, wherein the concentration of active agent at the outer surface of the device at the time of...
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6074660 |
Absorbable polyoxaesters containing amines and/ or amido groups
The present invention describes a polyoxaester copolymers containing amines and/or amido groups and blends thereof with other polymers that may be used to produce surgical devices such as sutures,...
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6068851 |
Formulation for use in the prevention of pathogen induced diseases including HIV and HSV
This invention relates to formulations comprising film-forming components capable of forming per se a physical barrier to pathogens. Thermoreversible gels such as poloxamers are particularly...
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5994151 |
Selenium carrier conjugates
The invention provides a method for making a selenium-carrier conjugate by covalently attaching (i) an organic selenium compound selected from the group consisting of RSeH, RSeR, RSeR', RSeSeR and...
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5989581 |
Drug delivery system for two or more active substances
The present invention is dealing with a drug delivery system, preferably in a ring-shaped form suitable for vaginal administration, for the simultaneous release of a progestogenic steroid compound...
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5985313 |
Method for decreasing the frequency of transmission of viral infections using cellulose acetate phthalate or hydroxypropyl methylcellulose phthalate excipients
A method for decreasing the frequency of transmission of human immunodeficiency virus or herpesviruses by administering to a human an anti-human immunodeficiency virus amount or an anti-herpesvirus...
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5965276 |
Method of forming a membrane especially a latex or polymer membrane including multiple discrete layers
Single and multiple layer membranes such as gloves and condoms include one or more deactivating barrier layers and/or indicating layers to indicate to a user membrane breach or the presence of a...
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5912006 |
Compositions and methods for alleviating discomforting menstrual pain
There is disclosed a composition and method for reducing or alleviating the discomforting symptoms associate with menstruation, particularly menstrual pain. The composition is administered by...
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5869081 |
Progesterone vaginal ring for treatment of infertility
The present invention relates to a method of administering progesterone to a normogonadal or a functionally agonadal human female undergoing an assisted reproduction technique. The invention...
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5844017 |
Prepolymers of absorbable polyoxaesters containing amines and/or amido groups
The present invention describes a prepolymer of aliphatic polyoxaesters containing amines and/or amido groups having polymerizable end groups that may be used to produce surgical devices such as...
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5788977 |
Method of making controlled release devices
A process is disclosed for making devices which release active material, e.g. a drug, at a controlled rate, which device comprises a closed container and the active material. The device is made by...
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5700583 |
Hydrogels of absorbable polyoxaesters containing amines or amido groups
The present invention describes a crosslinked aliphatic polyoxaesters containing amines and/or amido groups and blends thereof with other polymers that may be used to produce surgical devices such...
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5595751 |
Absorbable polyoxaesters containing amines and/or amido groups
The present invention describes a new aliphatic polyoxaesters that is bioabsorbable and may be used to produce surgical devices such as sutures, sutures with attached needles, molded devices, and...
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5558877 |
Method and device for treatment of cancer
A medical device for insertion into a vaginal cavity comprising an elastomeric ring containing a compound selected from the group consisting of a compound of the formula ##STR1## wherein R 1 is...
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5545401 |
Antiviral, spermicidal vaginal gel and foam containing low molecular weight povidone-iodine
A virucidal, spermicidal vaginal gel consisting essentially of povidone iodine having a povidone to iodine ratio of about 15:1 or higher containing from about one percent to about twenty percent...
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5543150 |
Method of progesterone delivery and affect thereof
The present invention teaches that relatively low levels of serum progesterone, 1 to 6 ng/ml, may be used to prevent endometrial cancer. The vaginal delivery of progesterone using a cross-linked...
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5529782 |
Dissolvable device for contraception or delivery of medication
A dissolvable element containing an agent material is used for local administration of the agent material in an internal body area. The dissolvable element is made of dissolvable polymer material...
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5340585 |
Method and formulations for use in treating benign gynecological disorders
Compositions and methods which are effective to treat benign gynecological disorders for extended periods of time in women in who the risk of endometrial stimulation is minimized or absent are...
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5340584 |
Methods and formulations for use in inhibiting conception and in treating benign gynecological disorders
Compositions and methods which are effective to inhibit conception and to treat benign gynecological disorders for extended periods of time are described, wherein an effective amount of a...
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5211952 |
Contraceptive methods and formulations for use therein
Contraceptive devices which are effective for extended periods of time are described, in the form of means for releasing an effective amount of a gonadotropin hormone releasing hormone composition...
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5188835 |
Intravaginal devices
The invention concerns an intravaginal device comprising a combination of 17β-estradiol and a supporting matrix for treating hypoestrogenic women. The device releases continously 17β-estradiol at...
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5176907 |
Biocompatible and biodegradable poly (phosphoester-urethanes)
Biocompatible and biodegradable poly(phosphoester-urethanes), compositions comprising the poly(phosphoester-urethanes), and methods of use as a drug delivery device and an implant.
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5116619 |
Vaginal progesterone tablet
A vaginal progesterone suppository is provided in the form of a tablet which delivers biologically effective amounts of progesterone for at least about 48 hours, and blood amounts above basal...
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5080902 |
Article and a prophylactic composition containing a microbicide
A prophylactic agent for controlling venereal diseases. As an active microbicidal component, the agent has an ammonium compound having hydrolyzable ester group.
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5069906 |
Intra-vaginal device and method
The invention disclosed provides an intra-vaginal device prepared using ingredients which slowly release in the vagina over a significant period of time. The present intra-vaginal device also...
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5023082 |
Sustained-release pharmaceutical compositions
The present invention pertains to biodegradable sustained-release composins capable of achieving the sustained release of a pharmaceutical or other agent. The compositions can be formed into...
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4997653 |
Method for treating endometriosis with topical preparations containing danazol
A topical preparation of danazol comprising a matrix base, danazol retained therein, and optionally a release-promoting agent is provided. The topical preparation is more effective than oral...
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