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7605138 |
Nucleic acid compositions for stimulating immune responses
The invention provides an immunostimulatory nucleic acid comprising CpG motifs, and methods of use thereof in stimulating immunity.
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7592020 |
Personal care products with visual indicator of vaginitis
There is provided a personal care product having a body side liner, a baffle and an indicator strip with two ends. The indicator has an amine sensitive dye near at least one end. The indicator...
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7521064 |
Non-hormonal vaginal contraceptive
The present invention relates to a non-hormonal, biocompatible, and biodegradable intravaginal device for the delivery of spermiostatic, spermicidal and anti-infectious agents. The present...
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7456207 |
Vaginal pharmaceutical compositions and methods for preparing them
Vaginal pharmaceutical compositions are described. These compositions contain (i) an active pharmaceutical ingredient selected from the group consisting of antimicrobial imidazoles and mixtures...
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7442179 |
Pre-fill applicator
A pre-fill vaginal applicator comprising a tubular barrel having an open end and a dispensing end provided with at least one dispensing opening formed therein. A selectively removable closure, such...
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7427416 |
Methods of treating conditions using metal-containing materials
Methods of treating conditions using metal-containing materials are disclosed. Exemplary conditions include bacterial conditions, biofilm conditions, microbial conditions, inflammatory conditions,...
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7368127 |
Biomedical devices with peptide containing coatings
Biomedical devices with stable peptide coatings are provided. The coatings are formed by incorporating at least one latent reactive component into the reactive mixture, forming a medical device...
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7348023 |
Absorbent articles containing additives
Absorbent articles containing an additive are disclosed. The absorbent articles include an effective amount of an inhibitory compound, such as thiolactomycin or thiomalonate, to substantially...
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7341737 |
Medicated tampon
A tampon adapted to deliver a therapeutic agent, the tampon including a tampon body having a distal end; and a dosage form affixed to the distal end of the tampon body, wherein the dosage form...
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7332177 |
Method and formulation for treating resistance to antihypertensives and related conditions
A method for the prevention or treatment of symptoms of hypertension in a patient who is resistant to antihypertensive effects of an antihypertensive compound administered in the absence of...
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7312067 |
Lactic acid producing bacteria for use as probiotic organisms in the human vagina
The present invention discloses novel isolated strains of lactic acid producing bacteria of the genera Lactobacillus and Pediococcus , and a method for isolation of such bacterial strains,...
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7282214 |
Biomedical devices with antimicrobial coatings
Biomedical devices with antimicrobial coatings are provided. One or more surfaces of the device are coated with a cationic peptide, cationic proteins, or mixtures thereof to impart antimicrobial...
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7271156 |
Immunostimulatory nucleic acids
The invention relates to immunostimulatory nucleic acid compositions and methods of using the compositions. The T-rich nucleic acids contain poly T sequences and/or have greater than 25% T...
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7255881 |
Metal-containing materials
Metal-containing materials, as well as their preparation and use are disclosed. The metal-containing material can be, for example, an antimicrobial material, an anti-biofilm material, an...
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7235263 |
Processes for controlling microbial organic compound production
Processes for preparing products comprising an oxygen-generating additive for reducing the amount of skin irritation and inflamation and odor are disclosed. Specifically, products such as training...
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7195775 |
Protection of the female reproductive system from natural and artificial insults
Described are methods for protecting the female reproductive system against natural and artificial insults by administering to women a composition comprising an agent that antagonizes one or more...
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7138135 |
Bioadhesive, closed-cell foam film, sustained release, delivery devices and methods of making and using same
Bioadhesive, closed-cell foam film, sustained release, delivery devices for administering an active agent or combination of active agents to a subject are provided. Methods for making such delivery...
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7118759 |
Absorbent articles containing additives
Effective amounts of the inhibitory compounds described herein capable of significantly reducing the production of TSST-1 are as follows: (1) compounds of Structure (I): from about 0.0001...
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7109255 |
Bioresorbable hydrogel compositions for implantable prostheses
Crosslinked compositions formed from water-insoluble copolymers are disclosed. These compositions are copolymers having a bioresorbable region, a hydrophilic region and at least two cross-linkable...
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7056495 |
Solid dose delivery vehicle and methods of making same
The present invention encompasses a solid dose delivery vehicle for ballistic administration of a bioactive material to subcutaneous and intradermal tissue, the delivery vehicle being sized and...
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7049346 |
Swollen hydrogel for sphincter augmentation
A physiologically acceptable composition comprises a plurality of physiologically acceptable hydrogel particles which have been swollen in a water solution containing a low molecular weight water...
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7041310 |
Pharmaceutical preparation for the treatment of gynecological diseases
This invention provides to a novel pharmaceutical preparation for the treatment of gynecological diseases. The pharmaceutical preparation according to the invention comprises a therapeutic drug for...
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7018645 |
Mixtures of various triblock polyester polyethylene glycol copolymers having improved gel properties
A water soluble, biodegradable reverse thermal gelation system comprising a mixture of at least two types of tri-block copolymer components is disclosed. The tri-block copolymer components are made...
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7005138 |
Method of systematically delivering SSRIs
Methods and compositions are disclosed for the intravaginal or rectal delivery of selected serotonin reuptake inhibitors (SSRIs) to the systemic circulation. Such methods and compositions are...
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6986901 |
Gastrointestinal compositions
The invention relates to compositions and methods for treating and/or preventing lower gastrointestinal (GI) disorders in mammalian patients, more particularly for alleviating and/or preventing the...
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6982091 |
Vaginal delivery of chemotherapeutic agents and inhibitors of membrane efflux systems for cancer therapy
Devices, methods, and compositions for cancer therapy by administration of chemotherapeutic agents and/or inhibitors of membrane efflux systems to the vagina for topical and systemic tumor targets.
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6951654 |
Intravaginal drug delivery devices for the administration of an antimicrobial agent
An intravaginal antimicrobial drug delivery device is disclosed having an antimicrobial agent dispersed throughout a biocompatible elastomeric system. Also disclosed is a method of making the...
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6949255 |
Inhibitory chemical formulation with preservative system
The present invention provides methods for preventing the transmission of HIV, methods for prophylaxis of HIV transmission and methods for reducing the risk of HIV transmission vaginally or...
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6939558 |
Intravaginal devices containing progesterone for estrus synchronization and related proceses
Embodiments of the present invention generally relate to devices and processes related to estrus synchronization. Particular embodiments of devices and processes of the present invention slowly...
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6923990 |
Stabilized silver-ion amine complex compositions and methods
The present invention relates to new silver-ion super-complex compositions. More particularly, the present invention describes silver-ion super-complex compositions comprising a silver-thiosulfate...
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6923988 |
Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
The present invention provides solid pharmaceutical compositions for improved delivery of a wide variety of pharmaceutical active ingredients contained therein or separately administered. In one...
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6916485 |
Prolonged release bioadhesive therapeutic systems
The present invention concerns a prolonged release bioadhesive mucosal therapeutic system containing at least one active principle, with an active dissolution test of more than 70% over 8 hours and...
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6905701 |
Formulations for transmucosal vaginal delivery of bisphosphonates
Devices, methods, and improved formulation for transmucosal vaginal delivery of bisphosphonates. A targeted site delivery of bisphosphonates to the systemic circulation using a vaginal device...
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6899890 |
Bioadhesive drug delivery system
The present invention relates to a novel essentially pH neutral vaginal drug delivery system suitable for modified delivery of a therapeutically active material in the vaginal cavity. The vaginal...
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6899874 |
Method for the treatment of bacterial vaginal infections
A composition for treatment of bacterial infections of the eye is disclosed which comprises a lytic enzyme composition specific for the infecting bacteria, and a carrier for delivering said lytic...
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6890547 |
Glycyrrhizin preparations for transmucosal absorption
By blending glycyrrhizin with an ester mixture comprising a C 6-18 fatty acid glycerol ester with a C 6-18 fatty acid macrogol ester, glycyrrhizin can be efficiently absorbed via mucosae, in...
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6887496 |
Products for controlling microbial organic compound production
Products comprising an oxygen-generating additive for reducing the amount of skin irritation and inflamation and odor are disclosed. Specifically, products such as training pants and diapers are...
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6881403 |
Tampon for the treatment of Streptococcus Group B infections of the vagina
A tampon for treatment of Streptococcus Group B infections of the vagina is disclosed which comprises a lytic enzyme composition specific for the infecting bacteria, and a carrier for delivering...
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6878369 |
Methods for treating urinary incontinence in mammals
Disclosed are methods for treating urinary incontinence in a mammal wherein a composition comprising a biocompatible polymer, a biocompatible solvent, and a contrast agent is delivered to the...
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6861060 |
Personal care formulations
Personal care and hygiene formulations for topical application to mucosal surfaces. These formulations include an amphiphilic lipid carrier in the form of a colloidal composition which can include...
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6858219 |
Methods for sterilizing male mammals
Disclosed are compositions suitable for use in embolizing blood vessels which compositions comprise a polymer, a biocompatible solvent and a contrast agent. The polymer is selected from the group...
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6835388 |
Medicament against dysmenorrhoea and premenstrual syndrome
A local anesthetic is used for the manufacture of a medicament for use against dysmenorrhoea and premenstrual syndrome and for increasing fertility. A pharmaceutical composition may also be used...
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6818672 |
Treating endometriosis or infertility, or improving fertility
The present invention concerns compositions and methods for using a β-adrenergic agonist for treating endometriosis, for treating infertility, and for improving fertility. The present invention...
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6761885 |
Strain of Lactobacillus plantarum and uses thereof
A novel strain of Lactobacillus plantarum , referred to as LB931, has now been isolated. The strain has been deposited at Deutsche Sammlung von Mikroorganismen, Braunschweig, DE. It has been...
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6756051 |
Bioadhesive, closed-cell foam film, sustained release, delivery devices and methods of making and using same
Bioadhesive, closed-cell foam film, sustained release, delivery devices for administering an active agent or combination of active agents to a subject are provided. Methods for making such delivery...
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6737068 |
Wipe formulation
The present invention relates to a liquid formulation for a feminine wipe. The preferred formulation has an anti-irritant agent, a pH adjuster namely citric acid, and at least one preservative.
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6706276 |
Compositions and methods for trapping and inactivating pathogenic microbes and spermatozoa
Antimicrobial and contraceptive compositions and methods which prevent and/or reduce the risk of transmission of sexually transmitted diseases through sexual activity as well as prevent and/or...
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6699494 |
Pharmaceutical composition and method for treating premature labor
The present invention teaches a composition comprising a β-adrenergic agonist in a bioadhesive carrier. Preferably, the composition comprises terbutaline in polycarbophil. The present invention...
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6696071 |
Pre-coital and post-coital rinse with anti-viral and skin-protective zinc salts
An aqueous douche or enema is disclosed, containing a water-soluble zinc salt at an anti-viral concentration, designed for use shortly before and/or shortly after intercourse. Unlike a lubricant...
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6689387 |
Phytochemicals for treatment of mastalgia and endometriosis
New compositions are disclosed that comprise the phytochemical Diindolylmethane (DIM), as well as its precursor, Indole-3-carbinol (I3C), and cogener, 2-(Indol-3-ylmethyl)-3,3′diindolylmethane...
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