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5110605 |
Calcium polycarbophil-alginate controlled release composition and method
A polymeric complex composition comprising a reaction complex formed by the interaction of a polycarbophil component with alginic acid or a salt thereof, said interaction being performed in the...
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5093127 |
Preparation of FR115224 substrate for parenteral administration
A cyclic peptide designated FR115224, administered parenterally in a cyclodextrin carrier, which exhibits antiallergic activity.
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5080902 |
Article and a prophylactic composition containing a microbicide
A prophylactic agent for controlling venereal diseases. As an active microbicidal component, the agent has an ammonium compound having hydrolyzable ester group.
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5069906 |
Intra-vaginal device and method
The invention disclosed provides an intra-vaginal device prepared using ingredients which slowly release in the vagina over a significant period of time. The present intra-vaginal device also...
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5061738 |
Blood compatible, lubricious article and composition and method therefor
A leach resistant composition includes a quaternary ammonium complex of heparin and a silicone. A method for applying a coating of the composition to a surface of a medical article is within the...
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5061487 |
Antimicrobial superabsorbent compositions and methods
An antimicrobial superabsorbent composition of a cross-linked hydrophilic sodium salt form of a partially neutralized acrylic acid-based polymer gel having covalently bonded thereto a silane. The...
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5035884 |
Methylene pyrrolidone copolymers for contact lens and pharmaceutical preparations
A new series of copolymers which are useful as coatings for solid dosage forms, for transdermal devices, for wound dressing materials, and for contact lenses. Also disclosed are methods for...
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5015474 |
Composition for imparting moisture to a substrate
Methods and compositions are provided for alleviating the dryness of a dermal or mucosal membrane substrate. The compositions are formulated from eriodictyon fluid which is a Yerba Santa extract...
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5015666 |
Triarylcyclopropanes as antiestrogens and antitumor agents
Triarylcyclopropane derivatives in which one or more of the aryl groups includes a hydroxy as a substituted or unsubstituted or alkoxy or side chain substituent. The compounds are useful as...
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5004694 |
Complement-dependent cytolytic anti-Trichomonas vaginalis monoclonal antibodies
Novel monoclonal antibodies specific to Trichomonas vaginalis, having complement--fixing ability and lysing Trichomonas vaginalis in the presence of complement are disclosed and may be used in...
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4997653 |
Method for treating endometriosis with topical preparations containing danazol
A topical preparation of danazol comprising a matrix base, danazol retained therein, and optionally a release-promoting agent is provided. The topical preparation is more effective than oral...
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4983393 |
Intra-vaginal device and method for sustained drug release
The invention disclosed provides an intra-vaginal device prepared using ingredients which slowly release in the vagina over a significant period of time. The present intra-vaginal device also...
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4981686 |
Personal lubricant
A personal lubricant which is not contraceptive, does not impede sperm motility and may contain healing ingredients.
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4961931 |
Method for the management of hyperplasia
The invention is for a vaginal dispenser comprising a wall surrounding an internal lumen and having a pair of ends with one end placed inside the other end to form a closed dispenser. A vaginally...
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4959216 |
Contraceptive methods and delivery systems thereof
A contraceptive method for living animals (including human beings) can utilize a polyurethane or polyvinylacetate (PVA) disc as an inert carrier for contraceptive preparations, the disc being...
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4879315 |
Cyclopropyl analogs as anti-estrogenic, anti-tumor and female fertility agents
Anti-estrogenic cyclopropyl analogs such as 1,1-dichlorocis-2,3-diphenylcyclopropane, when administered to a subject function as anti-tumor agents to prevent the development of estrogen-dependent...
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4874612 |
Multi-component long-acting medicament formulation for implantation
Multi-component implants which contain at least two shaped pieces containing active compound, wherein these shaped pieces contain biologically degradable copolymers of lactic acid and glycolic acid...
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4873087 |
Suppository preparation having excellent absorption property
A preparation containing an absorption promoter selected from N-acyl amino acid derivatives or N-acyl peptide derivatives represented by the formula: R-CO-A (R is an aliphatic hydrocarbon group, an...
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4837111 |
Dosage form for dispensing drug for human therapy
An osmotic dosage system is disclosed for delivering the therapeutically beneficial drug doxazosin to an environment of use over time.
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4822616 |
Vaginal ring
A vaginal ring comprises a supporting ring 1 free of active agent. A layer 2, which contains an active agent such as a steroid, is applied on its outer rim, optionally in a continuous groove...
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4816257 |
Method for producing an in vivo environment suitable for human embryo transfer
A method for producing, in a functionally agonadal human female body, an environment suitable for the implantation, nutrition, and development of an embryo, comprising the placement of at least one...
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4801444 |
Medicinal preparation for individual prevention of venereal diseases and treatment of urogenital trichomoniasis
A medicinal preparation for individual prevention of venereal diseases and treatment of urogenital trichomoniasis comprises an efficient quantity of an active principle which is essentially a...
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4788060 |
Multiple electrolyte douche and wipe composition
A disposable feminine hygiene kit and system that includes a douche composition for internal cleansing of the vagina, and a wipe solution for external cleansing of the vulva. The douche formulation...
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4786500 |
Programmable agent delivery system
This invention pertains to a programmable delivery system.
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4722937 |
Antitoxin vaginal products and catamenials
A method of prophylactics with respect to detoxification of Staphylococcus aureus and other toxins by ascorbic acid, salts and esters, topically applied by means of carriers which are otherwise...
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4722936 |
Deodorization vaginal products and catamenials
A method of prophylactics with respect to deodorization by ascorbic acid, salts and esters, topically applied by means of carriers which are otherwise regularly employed in the vaginal area, such...
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4693705 |
Vaginal contraceptive system
The invention features an innovative vaginal sponge contraceptive device that has active spermicide. The active spermicide allows the device to be used instantly upon removal from its sealed...
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4692143 |
Unit package containing ready-to-use vaginal contraceptive
A premoistened ready-for-use vaginal contraceptive device and method of use thereof are described wherein a porous polyurethane sponge is provided which is impregnated with a bacteria-free sterile...
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4678463 |
Devices for insertion into a body cavity of an animal and/or applicators therefor
A device for insertion into a body cavity of an animal and for producing a controlled rate of release of chemicals into the body of the animal, has a spine with a body and legs hinged to the body,...
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4649042 |
Rumen delivery device
An improved device for delivery of a medicament to the digestive tract of a ruminant animal comprises a polymeric medicated core retained in a dense tube by a relatively thick layer of an elastic...
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4553972 |
Disposable intravaginal contraceptive devices releasing 1-substituted imidazoles
Devices, of suitable form and size for insertion into the vagina of a female mammal, composed of a polymeric material which has, incorporated in it, a 1-substituted imidazole spermicide and a...
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4551148 |
Vaginal delivery systems and their methods of preparation and use
Systems and their methods of preparation and use that release an active agent in a controlled manner for an extended period in a vaginal cavity environment. The systems are capable of delivering...
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4526578 |
Vaginal diaphragm
A vaginal diaphragm is disclosed comprising an annular reservoir housing a beneficial agent, and in a preferred embodiment the diaphragm film embraces a means for containing and releasing a...
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4493699 |
Contraceptive methods
Long chain alkyl and alkenyl sulfonates, sulfates and sulfoalkyl alkanoate salts, administered intravaginally for contraception.
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4475916 |
Osmotic drug delivery system
An osmotic drug (or other beneficial substance) delivery system comprises a compartment with one or more chambers in series formed by an external shell and chamber-dividing walls of a microporous...
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4462989 |
Method and agents for arresting infection
A method and associated agents for the arrest of infections resulting from organism growth in contact with an iron-containing body fluid, comprising administering an agent capable of immobilizing...
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4452775 |
Cholesterol matrix delivery system for sustained release of macromolecules
Delivery systems for releasing macromolecular active agents to a body site at a controlled rate for a prolonged period of time, comprising a cholesteric matrix permeable to passage of the...
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4449980 |
Methods of making intra-vaginal devices and/or intra-vaginal devices
An intra-vaginal device for supplying minerals, hormones or medicoments to an animal is formed as an injection moulded polymeric body having a skin in which adjacent at least part of the surface...
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4449983 |
Simultaneous delivery of two drugs from unit delivery device
An osmotic device is disclosed for delivering two beneficial drugs to an environment of use. The device comprises a wall surrounding a lumen divided into a first compartment containing a drug that...
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4402693 |
Medicated device holder
A medicated device comprises a substantially cylindrical, hollow body member having radially outwardly extending annular ridges at each end, a lengthwise slot, and inwardly extending flanges along...
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4391797 |
Systems for the controlled release of macromolecules
Delivery systems manufactured in the form of polymeric compositions for the controlled delivery of macromolecules to environments of use are disclosed. The systems are characterized as two-phase...
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4381772 |
Bioerodible diaphragm
An improved contraceptive diaphragm is provided which has a bioerodible matrix that disintegrates in the vaginal fluids within a predetermined period of time. The matrix is made from a water...
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4369172 |
Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
A carrier base material combined with a therapeutically active medicament and shaped and compressed to a solid unit dosage form having a regular and prolonged release pattern upon administration,...
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4326525 |
Osmotic device that improves delivery properties of agent in situ
An osmotic device is disclosed that provides a means for improving the delivery properties of a beneficial agent in situ.
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4326510 |
Barrier contraceptive torus
A barrier contraceptive device and a method for preventing conception utilizing the device. The device comprises a torus of biocompatible material sized to fit in a vagina, structure--such as...
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4320759 |
Dispenser with diffuser
A system is disclosed for delivering a beneficial agent at a substantially constant rate over time. The system comprises (1) a wall formed of a microporous polymer, or (2) a wall formed in part of...
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4312347 |
Positive pressure drug releasing device
A positive pressure long-term drug delivery device particularly useful for the intravaginal or intrauterine release of a drug capable of passing through a diffusion membrane and being absorbed by...
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4309996 |
System with microporous releasing diffusor
A system is disclosed for delivering a beneficial agent at a substantially constant rate over time. The system comprises (1) a wall formed of a microporous polymer, or (2) a wall formed in part of...
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4304226 |
Vaginal contraceptive
Improved reinforced devices, which can be retained in the vagina during intercourse, deliver spermicidal surfactants and provide contraceptive benefits. Lobed devices provide channels through which...
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4274410 |
Intravaginal contraceptive and drug release device and method for making and using same
A contraceptive device and method of contraception as well as a method of making the contraceptive device are described. Native collagen form of fibrillar protein is comminuted and homogenized in...
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