|
Match
|
Document |
Document Title |
|
|
7618643 |
Growth factor delivery system for the healing of wounds and the prevention of inflammation and disease
The present invention features hydrogel drug delivery systems and methods of producing and using such systems for the treatment of wounds. The systems are based on a hydrogel into which a low...
|
|
|
7601361 |
Process for providing antimicrobial surfaces
Processes for providing durable antimicrobial surfaces are disclosed that comprise treating a polymer substrate surface with formaldehyde followed by treatment with an antimicrobial peptide....
|
|
|
7584630 |
Photochromic ocular devices
Described are photochromic ocular devices such as contact lenses and intraocular lenses made of an organic polymeric material and at least one photochromic material capable upon exposure to actinic...
|
|
|
7569212 |
Procedure and composition of treatment and/or care of the eye
A procedure for the manufacture of contact lenses for eye treatment, eye protection and eye-care wherein the lenses are impregnated with a suitable composition, a composition for the impregnation...
|
|
|
7556822 |
Biomedical compositions
A method of preparing intraocular lenses in situ is disclosed. The method involves the injection of an unsaturated macromonomer of Formula I:
The macromonomer is then polymerized to give a...
|
|
|
7416737 |
Antimicrobial lenses, processes to prepare them and methods of their use
This invention relates to solutions for packaging ophthalmic devices comprising at least one antimicrobial metal salt which prevent the loss of said antimicrobial metal salt during autoclaving and...
|
|
|
7402562 |
Composition for stabilizing corneal tissue during or after orthokeratology lens wear
An orthokeratological procedure is provided that prevents or retards relaxation of corneal tissue back to the original anterior curvature of the cornea. The procedure comprises applying a...
|
|
|
7368127 |
Biomedical devices with peptide containing coatings
Biomedical devices with stable peptide coatings are provided. The coatings are formed by incorporating at least one latent reactive component into the reactive mixture, forming a medical device...
|
|
|
7351430 |
Shape-retentive hydrogel particle aggregates and their uses
The present invention is related to hydrogel particles and aggregates formed therefrom having characteristics including, without limitation, shape-retentiveness, elasticity, controllable pore sizes...
|
|
|
7348022 |
Biomedical composition
A method of preparing intraocular lenses in situ is disclosed. The method involves the injection of an unsaturated macromonomer of the formula
The macromonomer is then polymerized to give a...
|
|
|
7329415 |
Materials containing multiple layers of vesicles
The present invention provides a composite material, preferably an ophthalmic device, more preferably a contact lens, which comprises a vesicle-containing coating including at least one layer of a...
|
|
|
7326423 |
Copolymerizable azo compounds and articles containing them
Polymerizable light absorbing azo dyes are disclosed useful as monomers in the formation of devices such as, but not limited to ocular lenses. Specifically, intraocular lenses (IOL) are disclosed...
|
|
|
7303278 |
Multifocal contact lens
A contact lens formed from a transparent material having front and rear surfaces, wherein the rear surface has a base curve which is adapted to fit an eye of a wearer of the lens. The front surface...
|
|
|
7282214 |
Biomedical devices with antimicrobial coatings
Biomedical devices with antimicrobial coatings are provided. One or more surfaces of the device are coated with a cationic peptide, cationic proteins, or mixtures thereof to impart antimicrobial...
|
|
|
7249848 |
Wettable hydrogels comprising reactive, hydrophilic, polymeric internal wetting agents
The present invention relates to wettable silicone hydrogels comprising the reaction product of at least one siloxane containing component and at least one reactive, hydrophilic polymeric internal...
|
|
|
7169406 |
Growth factor delivery systems for the healing of wounds and the prevention of inflammation and disease
The present invention features hydrogel drug delivery systems and methods of producing and using such systems for the treatment of wounds. The systems are based on a hydrogel into which a low...
|
|
|
7105352 |
Intelligent polymerized crystalline colloidal array carbohydrate sensors
The present invention is related to glucose sensors that are capable of detecting the concentration or level of glucose in a solution or fluid having either low or high ionic strength. The glucose...
|
|
|
7060288 |
Biomedical devices
The present invention is concerned with biomedical device comprising
(a) a biocompatible organic or inorganic bulk material and (b) a coating comprising polymerizable carbon-carbon double...
|
|
|
6982090 |
More easily visualized punctum plug configurations
An improved punctum plug is more easily visualized when positioned within a punctual canal of a recipient. The body of the plug features an outwardly exposed surface when properly positioned, and a...
|
|
|
6902548 |
Use of Streptomyces hyalurolyticus enzyme in ophthalmic treatments
A highly specific and easily purified form of hyaluronidase is described for use in ophthalmic treatments. The enzyme, from Streptomyces hyalurolyticus is specific for hyaluronidase and carries...
|
|
|
6900188 |
System for treating wounds and method for producing this system
The wound-treatment system is natural and is adapted to change state in a reversible manner by passing from the gel state to the solution state and vice-versa, and has polysaccharide macromolecules...
|
|
|
6787131 |
Method for enhancing integrity of epithelium using retinoic acid
A method for improving the integrity of the corneal epithelium by introducing into the eye an effective amount of a ophthalmically compatible retinoid sufficient to enhance the integrity of the...
|
|
|
6767934 |
Macromolecular compounds
Macromolecular photocrosslinkers have polymeric backbones of substituted siloxane groups carrying photoactive groups. When exposed to light of wavelength above 305 nm, the photocrosslinkers are...
|
|
|
6726918 |
Methods for treating inflammation-mediated conditions of the eye
Methods for treating inflammation-mediated conditions of the eye are described, comprising: implanting into the vitreous of the eye of an individual a bioerodible implant comprising a steroidal...
|
|
|
6610318 |
Sterile ophthalmological gel preparation applicable in drops and process for producing it
The invention relates to a sterile ophthalmic drop preparation, especially a gel preparation, which comprises a two-phase carrier liquid or gel basis comprising a liquid aqueous and a liquid...
|
|
|
6592814 |
Biomedical devices with antimicrobial coatings
Contact lenses with antimicrobial coatings are provided. One or more surfaces of the lenses are coated with lactoferrin to impart antimicrobial properties to the surface.
|
|
|
6589550 |
Methods of producing intraocular lenses and materials suitable for their production
A method for producing an intraocular lens, comprising the steps of injecting a high-refractive index, low viscosity composition of crosslinkable units into an enclosure and initiating...
|
|
|
6555582 |
Eye treatments using synthetic thyroid hormone compositions
The present invention involves the discovery that synthetic thyroid hormones can be used as compositions to reduce intraocular pressure in vivo. Methods of screening synthetic thyroid hormones for...
|
|
|
6537545 |
Use of corneal hardening agents in enzymeorthokeratology
An Enzyme Orthokeratology method is provided for correcting refractive errors in the eye of a subject mammal. Accelerating reshaping of the cornea is accomplished by administering a corneal...
|
|
|
6410045 |
Drug delivery system for antiglaucomatous medication
A drug delivery system for antiglaucomatous medications utilizing a polymeric hydrogel which can absorb an ophthalmic medication which can then be transferred into the ocular fluid of the eye.
|
|
|
6368615 |
Contact lens having a pharmaceutical agent releasably disposed therein
A contact lens having a pharmaceutical agent releasably disposed therein. The lens itself comprises a polymer of an unsaturated carboxylic acid ester of salicylic acid, the unsaturated carboxylic...
|
|
|
6346560 |
Method for selecting contact lens materials to minimize corneal staining
The invention provides a method for selecting contact lenses to reduce corneal staining. The method selects contact lens materials based upon the ratio of the water diffusion coefficient to the ion...
|
|
|
6316669 |
Bis-amido polybiguanides and the use thereof to disinfect contact lenses and preserve pharmaceutical compositions
Bis-amido polybiguanides and their use as antimicrobial agents in pharmaceutical compositions are disclosed. A method of synthesis of bis-amido polybiguanides is also disclosed. The bis-amido...
|
|
|
6312706 |
Prepolymers useful in biomedical devices
A novel polyurethane based prepolymer useful in biomedical devices which provides high oxygen permeability and superior physical properties.
|
|
|
6296867 |
Therapeutic contact lens comprising living cells within a matrix
A theraputic lens for removable placement onto a surface of a cornea of an eye, and methods for making and using the same. The lens has a first surface adapted for exposure to light and a second...
|
|
|
6228355 |
System for the control of enteropathogenic bacteria in the crops of poultry
The invention provides a method and compositions for controlling food borne enteric bacterial pathogens in poultry populations. The incidence of the colonization of poultry by enteropathogenic...
|
|
|
6217896 |
Conjunctival inserts for topical delivery of medication or lubrication
The present invention provides an improved conjunctival insert for topical delivery of medication or lubrication into the conjunctival spaces and upon the ocular surface of human eye. Specifically,...
|
|
|
6132735 |
Enzyme-orthokeratology
A method and apparatus for correcting refractive errors of the eye are disclosed. Accelerated reshaping of the corneal tissue is accomplished by administering one or more enzymes and/or other...
|
|
|
6106889 |
Method of selective coating of articles
Articles such as medical devices are selectively coated with a lubricious coating. A temporary coating, formed from an aqueous solution of a water-soluble polymer of low to moderate molecular...
|
|
|
6099852 |
Wettable silicone-based lenses
This invention provide silicone-based, biomedical devices that exhibit improved wettability as well as biocompatability through the use of functional silane agents. More specifically, the invention...
|
|
|
6077714 |
Method for the preparation of free radical pharmaceuticals diagnostics and devices using selenium conjugates
The invention provides a method for making a selenium-carrier conjugate by covalently attaching (i) an organic selenium compound selected from the group consisting of RSeH, RSeR, RSeR', RSeSeR and...
|
|
|
6022553 |
Method of making a blood-compatible antimicrobial surface
A method for making antimicrobial, blood-compatible surfaces is provided, articles having surfaces made by this method, and the use of these articles in fields where controlling the spread of...
|
|
|
6015213 |
Ring for a hard contact lens and hard contact lens composite employing such a ring
A ring for a hard contact lens, which can be detachably attached to the peripheral edge of a hard contact lens and which has a groove of a shape corresponding to the peripheral edge of the hard...
|
|
|
6011082 |
Process for the modification of elastomers with surface interpreting polymer networks and elastomers formed therefrom
A process for forming a surface modification on a polymer substrate and polymer substrates having such surface modifications. The process comprises the steps of absorbing a swelling monomer into...
|
|
|
5965088 |
Method for providing rapid disinfection of contact lenses
The present invention is directed to method of disinfecting a contact lens with an ophthalmically safe disinfecting aqueous solution comprising about 2.0 to about 8.0 ppm of a bis(biguanide) having...
|
|
|
5942558 |
Hydrogel lens pre-coated with lipid layer
A storage solution for a hydrogel contact lens comprising a material having polar groups at one end and non-polar groups at the other end. The storage solution desirably further contains an oil....
|
|
|
5900246 |
Drug incorporating and releasing polymeric coating for bioprosthesis
In accordance with the present invention, there are provided prosthetic articles having polyurethane coatings with biologically active compounds incorporated within the interstices of the polymer....
|
|
|
5885566 |
Surface modified surgical instruments, medical devices, implants, contact lenses and the like
Improved medical devices and instruments prepared by an improved method of producing hydrophilic, gamma-irradiation induced polymerized and chemically grafted coatings on plastic surfaces of...
|
|
|
5854303 |
Polymer, article and method for inhibiting the growth of ocular pathogens in eye care products
A polymeric material incorporating a polyvalent cation chelating agent in an amount effective to inhibit the growth of an ocular pathogen, particularly a protozoan, can be used to produce eye care...
|
|
|
5847023 |
Thermal irreversible gel corneal contact lens formed in situ
Balanced pH, thermo-irreversible gels comprising a polyoxyalkylene compound and an ionic polysaccharide are ideal materials for the formation of a protective contact lens over the cornea of the eye...
|