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8969415 Intraocular drug delivery systems  
Biodegradable implants sized and suitable for implantation in an ocular region or site and methods for treating ocular conditions. The implants provide an extended release of an active agent at a...
8962009 Sustained release intraocular implants and related methods  
Biocompatible intraocular implants include a steroid and a polymer associated with each other to facilitate release of the steroid into an eye for a period of time greater than about two months....
8945600 Methods of delivering pharmaceutical agents  
Provided are methods of delivering at least one pharmaceutical agent to the central nervous system (CNS) of a subject, methods of treating a neurological disorder or pain in a subject that include...
8927005 Liquid formulations for treatment of diseases or conditions  
Described herein are liquid formulations which deliver a variety of therapeutic agents, including but not limited to rapamycin, to a subject for an extended period of time; liquid formulations...
8911768 Methods for treating retinopathy with extended therapeutic effect  
Methods for treating and preventing retinopathic conditions by administering an anti-VEGF compound to the vitreous chamber of a patient at risk of, or suffering from, the retinopathy.
8911767 Hypotensive lipid-containing biodegradable intraocular implants and related methods  
Biocompatible intraocular implants include a prostamide component and a biodegradable polymer that is effective in facilitating release of the prostamide component into an eye for an extended...
8906406 Mucoadhesive dispersible pharmaceutical preparation for active-agent dosing in veterinary and human medicine  
The invention relates to a mucoadhesive medicinal preparation for administering active substances in veterinary or humane medicine, containing at least one active substance, which preparation is...
8900622 Hypotensive lipid-containing biodegradable intraocular implants and related methods  
Biocompatible intraocular implants include a prostamide component and a biodegradable polymer that is effective in facilitating release of the prostamide component into an eye for an extended...
8877229 Controlled release microparticles  
Formulations for controlled, sustained release of biologically active agents for the treatment of ocular disorders have been developed. These formulations are based on solid microparticles formed...
8871241 Injectable sustained release delivery devices  
An injectable drug delivery device includes a core containing one or more drugs and one or more polymers. The core may be surrounded by one or more polymer outer layers (referred to herein as...
8852652 Mucosal formulation  
Provided, among other things, is a method of treating or ameliorating an indication of mucosal or adjacent tissue comprising periodically applying to mucosa at or adjacent to disease affected...
8846073 Low temperature processes for making cyclic lipid implants for intraocular use  
Biocompatible implants comprising a cyclic lipid therapeutic agent are made using a low temperature melt extrusion process. The implants are suitable for intraocular use to treat an ocular condition.
8802129 Methods for treating retinopathy with extended therapeutic effect  
Methods for treating and preventing retinopathic conditions by administering a glucocorticoid to the vitreous chamber of a patient at risk of, or suffering from, the retinopathy.
8802128 Steroid-containing sustained release intraocular implants and related methods  
Biocompatible intraocular implant systems are formulated for discontinuous or intermittent release of therapeutic levels of a therapeutic agent (such as a steroid) to minimize development of side...
8790684 Vascular closure device  
A biocompatible material may be configured into any number of implantable medical devices including a vascular closure device. The vascular closure device includes a fibrous structure formed from...
8715713 Solvent cast film sustained release latanoprost implant  
The present invention provides a sustained release latanoprost implant in the form of a thin film comprising latanoprost incorporated in a biodegradable polymer matrix. Preferably, said implant is...
8673338 Methods of delivering pharmaceutical agents  
Provided are methods of delivering at least one pharmaceutical agent to the central nervous system (CNS) of a subject, methods of treating a neurological disorder or pain in a subject that include...
8673341 Intraocular pressure reduction with intracameral bimatoprost implants  
The present invention provides a method of treating an ocular condition in an eye of a patient, comprising the step of placing a biodegradable intraocular implant in an eye of the patient, the...
8668920 Method, device, and system for delivery of therapeutic agents to the eye  
A method, device, and system for easier, consistent, and comfortable delivery of therapeutic agents to the front of the eye.
8652500 Particulate tissue graft with components of differing density and methods of making and using the same  
Disclosed are tissue graft compositions made of particles having different densities, methods of making these compositions, and methods of using these compositions for promoting tissue restoration...
8647659 Intracameral sustained release therapeutic agent implants  
Described herein are intracameral implants including at least one therapeutic agent for treatment of at least one ocular condition. The implants described herein are not anchored to the ocular...
8642067 Methods and compositions for intraocular administration to treat ocular conditions  
Anti-angiogenesis compositions, and methods of using such compositions, useful for injection into the vitreous of human eyes are provided. Such compositions can include TKI component solutions or...
8642068 Bioabsorbable medical device with coating  
A biodegradable, bioabsorbable medical device with a coating for capturing progenitor endothelial cells in vivo and delivering a therapeutic agent at the site of implantation. The coating on the...
8632813 Prostaglandin compositions and methods for the treatment of vasospasm  
Compositions and methods for the treatment of vasospasm are provided comprising applying an amount of a semi-solid vasoactive prostaglandin composition to the affected tissue. Also provided are...
8603511 Fragmented polymeric compositions and methods for their use  
Cross-linked hydrogels comprise a variety of biologic and non-biologic polymers, such as proteins, polysaccharides, and synthetic polymers. Such hydrogels preferably have no free aqueous phase and...
8580292 Sustained release intraocular implants and methods for treating ocular vasculopathies  
Biocompatible intraocular implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2...
8529927 Alpha-2 agonist polymeric drug delivery systems  
Biocompatible intraocular implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2...
8529938 Combinations of viscoelastics for use during surgery  
An improved viscoelastic composition useful in the performance of ophthalmic surgical procedures and especially cataract procedures is disclosed. The embodiments of the composition comprise...
8512736 Coatings including natural biodegradable polysaccharides and uses thereof  
Biodegradable coatings and articles that include natural biodegradable polysaccharides are described. The coatings and articles are formed from a plurality of natural biodegradable polysaccharides...
8512738 Biodegradable intravitreal tyrosine kinase implants  
Biocompatible intraocular implants include a tyrosine kinase inhibitor and a biodegradable polymer that is effective to facilitate release of the tyrosine kinase inhibitor into the vitreous of an...
8506986 Sustained release intraocular implants and methods for treating ocular vasculopathies  
Biocompatible intraocular implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2...
8506987 Ocular implant made by a double extrusion process  
The invention provides biodegradable implants sized for implantation in an ocular region and methods for treating medical conditions of the eye. The implants are formed from a mixture of...
8501290 Implantable medical devices fabricated from polyurethanes with biodegradable hard and soft blocks and blends thereof  
Medical devices, such as stents, fabricated at least in part from a polymer composite including a biodegradable elastomeric phase dispersed within a biodegradable polymeric matrix are disclosed....
8481069 Tyrosine kinase microspheres  
Biocompatible intraocular microspheres include a tyrosine kinase inhibitor and a biodegradable polymer that is effective to facilitate release of the tyrosine kinase inhibitor into the vitreous of...
8469934 Pulsatile peri-corneal drug delivery device  
The present invention is directed to a pulsatile ophthalmic peri-corneal drug delivery device. The device includes an annular body and a mechanism for releasing multiple separate and distinct...
8465759 Process for the preparation of a hot-melt extruded laminate  
A process for the preparation of a bioadhesive laminate comprising a hot-melt extruded reservoir layer and a hot-melt extruded backing layer is provided. The reservoir layer comprises a...
8454691 Surgical correction of ptosis by polymeric artificial muscles  
A surgical procedure is described for the restoration of eyelid function in individuals suffering from ptosis or upper eyelid droop syndrome that makes a patient unable to voluntarily fully raise...
8440216 Sustained release intraocular implants and related methods  
Biocompatible intraocular implants include a steroid and a polymer associated with each other to facilitate release of the steroid into an eye for a period of time greater than about two months....
8435565 Bioresorbable polymer matrices and methods of making and using the same  
A bioerodible composition for delivery of a bioactive agent is the reaction product of a reaction mixture which includes an oxidized dextran solution, and a mixture of solids containing a...
8425929 Sustained release intraocular implants and methods for preventing retinal dysfunction  
Biocompatible intraocular implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2...
8409607 Sustained release intraocular implants containing tyrosine kinase inhibitors and related methods  
Biocompatible intraocular implants include a tyrosine kinase inhibitor and a biodegradable polymer that is effective to facilitate release of the tyrosine kinase inhibitor into an eye for an...
8377464 Polymerizable surfactants and their use as device forming comonomers  
This invention describes the use of polymerizable surfactants as comonomers in forming ophthalmic devices such as contact lenses, intraocular lenses, corneal implants, etc.
8367097 Liquid formulations for treatment of diseases or conditions  
Diseases and conditions associated with tissues of the body, including but not limited to tissues in the eye, can be effectively treated, prevented, inhibited, onset delayed, or regression caused...
8361139 Medical devices having metal coatings for controlled drug release  
Medical devices having a plurality of nanoparticles disposed over a surface of the medical device. The nanoparticles have a core comprising a therapeutic agent and a shell surrounding the core,...
8328774 Vision corrective jig and cooling fluid injection tool for the jig  
A jig and a cooling fluid injection tool are provided for use in the correction of corneal shape of an eyeball. Correction of the eyeball takes place while the cornea is warmed. The jig includes a...
8329203 Drug-containing implants and methods of use thereof  
The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides...
8309116 Personal care and cosmetics compositions comprising biologically-based mono and di esters  
Personal care compositions comprising esters of 1,3-propanediol and acceptable carriers are provided. The esters can have at least 3% biobased carbon, and the compositions can further comprise...
8298570 Sustained release intraocular implants and related methods  
Biocompatible intraocular implants include a steroid and a polymer associated with each other to facilitate release of the steroid into an eye for a period of time greater than about two months....
8293210 Sustained release intraocular implants and methods for preventing retinal dysfunction  
Biocompatible intraocular implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2...
8277828 Delivery system for bone growth promoting material  
A delivery system that includes a bone growth promoting material encapsulated within a water absorptive gelatinizable covering is used to promote bone growth in order to repair a bone defect...
Matches 1 - 50 out of 292 1 2 3 4 5 6 >