|
Match
|
Document |
Document Title |
|
|
7615235 |
Film-shaped or wafer-shaped pharmaceutical preparation with masked taste
The invention relates to thin film-shaped or wafer-shaped pharmaceutical preparations for oral administration of active substances. The preparations contain at least one matrix-forming polymer...
|
|
|
7592418 |
Biocompatible crosslinked polymers with visualization agents
Biocompatible crosslinked polymers, and methods for their preparation and use, are disclosed in which the biocompatible crosslinked polymers are formed from water soluble precursors having...
|
|
|
7592016 |
Methods for preparing and using implantable substance delivery devices
Method for preparing an implantable device for a sustained delivery of a substance within a body of a human or an animal subject, the method including; dissolving a biocompatible polymer in a...
|
|
|
7585517 |
Transscleral delivery
Diseases associated with the tissues in the posterior segment of the eye can be effectively treated by administering therapeutic agents transsclerally to those tissues. Compositions, devices, and...
|
|
|
7584630 |
Photochromic ocular devices
Described are photochromic ocular devices such as contact lenses and intraocular lenses made of an organic polymeric material and at least one photochromic material capable upon exposure to actinic...
|
|
|
7563455 |
Highly-mineralized osteogenic sponge compositions, and uses thereof
Osteogenic sponge compositions having enhanced osteoinductive properties for use in bone repair are described. The compositions include a quickly resorbable porous carrier, a more slowly resorbed...
|
|
|
7544368 |
Structure for modulating intraocular pressure
Embodiments of the present invention are directed to three-dimensional porous structures for modulating intraocular pressure. The structures can include a mixture of copolymers, for example,...
|
|
|
7510725 |
Process for producing a dura substitute
The invention relates to dura substitutes to be used as prostheses for dural defects in the field of neurosurgery and processes for producing the same. The present invention provides artificial...
|
|
|
7455855 |
Delivering substance and drug delivery system using the same
An object of the present invention is to prepare substances which are excellent in delivery and enable drugs to be retained in a body effectively over a long period and to construct a drug delivery...
|
|
|
7422642 |
Method for preparing chemical adsorption film and solution for preparing chemical adsorption film used in the method
To provide a method which allows the combination of rapid formation of a chemical adsorption film with the preparation of the film which is reduced in the content of impurities and having a dense...
|
|
|
RE40493 |
Porous paclitaxel matrices and methods of manufacture thereof
Paclitaxel is provided in a porous matrix form, which allows the drug to be formulated without Cremophor and administered as a bolus. The paclitaxel matrices preferably are made using a process...
|
|
|
7384649 |
Particulate compositions for pulmonary delivery
This invention concerns an improved particulate composition for delivering a drug to the pulmonary system. Applicants disclose a method of identifying an optimal form of aerodynamically light...
|
|
|
7374775 |
Dura substitute and a process for producing the same
The invention relates to dura substitutes to be used as prostheses for dural defects in the field of neurosurgery and processes for producing the same. The present invention provides artificial...
|
|
|
7335508 |
Porous plasma protein matrices and methods for preparation thereof
The present invention relates to porous freeze-dried plasma protein matrices having an open channel structure and a concentration gradient of plasma proteins crosslinked by the action of thrombin,...
|
|
|
7332566 |
Biocompatible crosslinked polymers with visualization agents
Biocompatible crosslinked polymers, and methods for their preparation and use, are disclosed in which the biocompatible crosslinked polymers are formed from water soluble precursors having...
|
|
|
7208177 |
Resorbable extracellular matrix for reconstruction of cartilage
A resorbable extracellular matrix for reconstruction of cartilage tissue includes a purified collagen II derived from natural cartilage tissue from which non-collagen proteins have been removed....
|
|
|
7160557 |
Matrices formed of polymer and hydrophobic compounds for use in drug delivery
A lipid or other hydrophobic or amphiphilic compound (collectively referred to herein as “hydrophobic compounds”) is integrated into a polymeric matrix for drug delivery to alter drug release...
|
|
|
7135190 |
Mixtures of various triblock polyester polyethylene glycol copolymers having improved gel properties
A water soluble, biodegradable reverse thermal gelation system comprising a mixture of at least two types of tri-block copolymer components is disclosed. The tri-block copolymer components are made...
|
|
|
7115551 |
Cleansing articles for skin or hair
The present invention relates to disposable, personal cleansing articles useful for cleansing the skin or hair. These articles are used by the consumer by wetting the dry article with water and...
|
|
|
7112417 |
Foam composite for the repair or regeneration of tissue
The present patent describes a biocompatible composite made of a first fibrous layer attached to a three-dimensional inter-connected open cell porous foams that have a gradient in composition...
|
|
|
7097855 |
Transdermal thermal polymerization
An invention for polymerizing or crosslinking a prepolymer using a water soluble, thermal polymerization initiator is disclosed. The prepolymer mixed with the initiator is injected or placed into...
|
|
|
7087237 |
Ocular solutions
Containing at least one macrolide antibiotic and/or mycophenolic acid provide anti-inflammatory, anti-cell proliferation, anti-cell migration, anti-angiogenesis, antimicrobial, and antifungal...
|
|
|
7087222 |
Method for enhancing integrity of epithelium using retinoic acid
A method for improving the integrity of the corneal epithelium by introducing into the eye an effective amount of a ophthalmically compatible retinoid sufficient to enhance the integrity of the...
|
|
|
7083803 |
Ocular solutions
Ocular solutions containing at least one macrolide antibiotic and/or mycophenolic acid provide anti-inflammatory, anti-cell proliferation, anti-cell migration, anti-angiogenesis, antimicrobial and...
|
|
|
7074412 |
Pharmaceutical composition
The present invention relates to pharmaceutical compositions containing a synergistic amount of at least one bone morphogenetic protein (BMP) and a synergistic amount of at least one pyrrolidone...
|
|
|
7037517 |
Polymer micelle as monolayer or layer-laminated surface
The present invention is directed to a coated biomedical device said micelle having a hydrophilic outer shell and a hydrophobic inner core, or a hydrophobic outer shell and a hydrophilic inner core...
|
|
|
7033605 |
Methods for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor
Methods for reducing or preventing transplant rejection in the eye of an individual are described, comprising: a) performing an ocular transplant procedure; and b) implanting in the eye a...
|
|
|
7033598 |
Methods and apparatus for enhanced and controlled delivery of a biologically active agent into the central nervous system of a mammal
Disclosed are invasive and non-invasive central nervous system (CNS) drug delivery methods and devices for use in these methods that essentially circumvent the blood-brain barrier. More...
|
|
|
7018645 |
Mixtures of various triblock polyester polyethylene glycol copolymers having improved gel properties
A water soluble, biodegradable reverse thermal gelation system comprising a mixture of at least two types of tri-block copolymer components is disclosed. The tri-block copolymer components are made...
|
|
|
7009034 |
Biocompatible crosslinked polymers
Biocompatible crosslinked polymers, and methods for their preparation and use, are disclosed in which the biocompatible crosslinked polymers are formed from water soluble precursors having...
|
|
|
6993406 |
Method for making a bio-compatible scaffold
A method for forming a three-dimensional, biocompatible, porous scaffold structure using a solid freeform fabrication technique (referred to herein as robocasting) that can be used as a medical...
|
|
|
6982090 |
More easily visualized punctum plug configurations
An improved punctum plug is more easily visualized when positioned within a punctual canal of a recipient. The body of the plug features an outwardly exposed surface when properly positioned, and a...
|
|
|
6969514 |
Method for treating elevated intraocular pressure, including glaucoma
Hyaluronic acid, a polymer found in the trabecular meshwork of the eye, has a polymeric structure that is broken down by the enzyme hyaluronidase. A method is provided for reducing elevated...
|
|
|
RE38827 |
Adhesive sealant composition
This invention is related to an adhesive composition which may be used to bond or seal tissue in vivo. The adhesive composition is readily formed from a two component mixture which includes a first...
|
|
|
6921541 |
Formulations and methods for providing prolonged local anesthesia
A formulation and methods for inducing sustained regional local anesthesia in a patient comprising a substrate comprising a local anesthetic and an effective amount of a biocompatible,...
|
|
|
6913767 |
Compositions for microencapsulation of antigens for use as vaccines
Methods and compositions are provided for the encapsulation of antigens in PLGA microspheres for use as vaccines. Such microspheres can also contain adjuvants. Mixtures of microspheres are provided...
|
|
|
6884518 |
Material suitable for an individual's tissue reconstruction
A material suitable for the reconstruction of an individual's tissue, particularly supportive tissue such as bone tissue, insertable into the tissue. The material is characterized by being composed...
|
|
|
6872404 |
Ophthalmologic uses of protein C
The present invention provides a method of reducing intraocular fibrin comprising the administration of a pharmacologically effective dose of Protein C to an individual having elevated levels of...
|
|
|
6808719 |
Drug delivery device
Drug delivery devices, and methods of delivering pharmaceutically active agents to a target tissue within a body using such devices, are disclosed. One drug delivery device includes a body having...
|
|
|
6761908 |
Collagen preparation for the controlled release of active substances
A collagen preparation for the controlled release of active substances is characterized in that it has mixtures of acid-insoluble collagens with different molecular weight distributions.
|
|
|
6748653 |
Method of making a temporary medical lead having biodegradable electrode mounting pad loaded with therapeutic drug
A method of making a temporary medical electrical lead for pacing or defibrillating a heart of a patient. The method comprises providing at least one electrical conductor having proximal and distal...
|
|
|
6726918 |
Methods for treating inflammation-mediated conditions of the eye
Methods for treating inflammation-mediated conditions of the eye are described, comprising: implanting into the vitreous of the eye of an individual a bioerodible implant comprising a steroidal...
|
|
|
6726664 |
Flow control device, introducer and method of implanting
An implant having a tube for permitting fluid flow has an outer flange at the outlet end and a retention projection near the inlet end. A delivery device for implanting the implant has a central...
|
|
|
6713081 |
Ocular therapeutic agent delivery devices and methods for making and using such devices
Ocular implant devices for the delivery of a therapeutic agent to an eye in a controlled and sustained manner. Dual mode and single mode drug delivery devices are illustrated and described....
|
|
|
6699493 |
Method for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor
Methods for reducing or preventing transplant rejection in the eye of an individual are described, comprising: a) performing an ocular transplant procedure; and b) implanting in the eye a...
|
|
|
6692759 |
Methods for preparing and using implantable substance delivery devices
Method for preparing an implantable device for a sustained delivery of a substance within a body of a human or an animal subject, the method including; dissolving a biocompatible polymer in a...
|
|
|
6656491 |
Active substance plasters
Active substance plasters consisting of a backing material and an at least partially applied adhesive composition, characterized in that a component comprising one or more active substances is...
|
|
|
6656490 |
Opthalmologic uses of protein C
The present invention provides a method of reducing intraocular fibrin comprising the administration of a pharmacologically effective dose of Protein C to an individual having elevated levels of...
|
|
|
6645978 |
Lipoxin A4 and its analogs for the treatment of dry eye
Ophthalmic compositions containing Lipoxin A 4 and its analogs and methods of their use for treating dry eve are disclosed.
|
|
|
6613735 |
Composition for polypeptide transfer to cells
The present invention is directed to a composition for gene transfer which composition contains a quaternary ammonium salt represented by formula (1): (wherein each of R 1 , R 2 , R 3 , R 4 ,...
|