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7618647 |
Using bucky paper as a therapeutic aid in medical applications
Methods, systems, and uses of bucky paper are provided in the present invention. These embodiments include covering medical implants with single or multiple layers of bucky paper, treating bucky...
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7618646 |
Matrix, cell implant and method for their production and use
The invention relates to porous matrices based on a biologically compatible polymer or polymer mixture, to a cell implantation that is established on said matrices and to additional cell...
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7592016 |
Methods for preparing and using implantable substance delivery devices
Method for preparing an implantable device for a sustained delivery of a substance within a body of a human or an animal subject, the method including; dissolving a biocompatible polymer in a...
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7585516 |
Coatings for drug delivery devices
A polymer coating for medical devices based on a polyolefin derivative. A variety of polymers are described to make coatings for medical devices, particularly, for drug delivery stents. The...
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7585320 |
Energetically-controlled delivery of biologically active material from an implanted medical device
A medical device and system capable of providing on-demand delivery of biologically active material to a body lumen patient, and a method of making such medical device. A first coating layer...
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7556822 |
Biomedical compositions
A method of preparing intraocular lenses in situ is disclosed. The method involves the injection of an unsaturated macromonomer of Formula I:
The macromonomer is then polymerized to give a...
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7531670 |
Methods for treating cognitive/attention deficit disorders using tetrahydroindolone analogues and derivatives
Methods for treating cognitive/attention deficit disorders in general using tetrahydroindolone derivatives and analogues, particularly tetrahydroindolone derivatives or analogues in which the...
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7510725 |
Process for producing a dura substitute
The invention relates to dura substitutes to be used as prostheses for dural defects in the field of neurosurgery and processes for producing the same. The present invention provides artificial...
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7498042 |
Stent for blood vessel and material for stent for blood vessel
A luminal stent, implanted and implanted and left in the blood vessel, is disclosed. By permitting a stent ( 1 ), formed of a biodegradable polymer material ( 2 ), to be swollen, and by...
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7494802 |
Amniotic membrane covering for a tissue surface and devices facilitating fastening of membranes
The present invention relates to a biopolymer covering for a tissue surface including, for example, a dressing, a bandage, a drape such as a bandage contact lens, a composition or covering to...
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7473431 |
Injectable methadone, methadone and naltrexone, or buprenorphine and naltrexone microparticle compositions and their use in reducing consumption of abused substances
An injectable slow-release methadone, partial opioid agonist or opioid antagonist formulation is provided comprising methadone, a partial opioid agonist or opioid antagonist in a poly(D,L-lactide)...
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7470469 |
Medical device having surface modification with superoxide dismutase mimic
A medical device comprising a substrate having a plasma polymerized functionality bonded to at least a portion of the substrate. A superoxide dismutase mimic agent having a complimentary functional...
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7452720 |
Apparatus for preparing a biocompatible matrix
An apparatus and method of using the apparatus to prepare a biocompatible biodegradable matrix capable of supporting cells to form an implantable or engraftable surgical device. A matrix-forming...
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7442384 |
Bioresorbable hydrogel compositions for implantable prostheses
Crosslinked compositions formed from water-insoluble copolymers are disclosed. These compositions are copolymers having a bioresorbable region, a hydrophilic region and at least two cross-linkable...
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7422849 |
Method for determining expression of a PI3 kinase gene
This invention relates to new polypeptides which exhibit kinase activity or, more specifically, which show phosphoinositide (PI) 3-kinase activity. Such polypeptides are involved in pathways...
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7374775 |
Dura substitute and a process for producing the same
The invention relates to dura substitutes to be used as prostheses for dural defects in the field of neurosurgery and processes for producing the same. The present invention provides artificial...
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7364748 |
Controlled morphologies in polymer drug for release of drugs from polymer films
The present invention includes a drug release system. The drug release system comprises a bulk polymer phase and a polymeric drug-enriched phase within the bulk polymer phase. At least one drug is...
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7364592 |
Biointerface membrane with macro-and micro-architecture
Disclosed herein are biointerface membranes including a macro-architecture and a micro-architecture co-continuous with and bonded to and/or located within at least a portion of the...
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7323425 |
Crosslinking of hyaluronan solutions and nanofiberous membranes made therefrom
A method for producing a non-chemically crosslinked hyaluronan is provided which involves contacting a sample of hyaluronan with an acidic solvent/water mixture for a period of time and at a...
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7303758 |
Local vascular delivery of mycophenolic acid in combination with rapamycin to prevent restenosis following vascular injury
Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to...
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7300662 |
Drug/drug delivery systems for the prevention and treatment of vascular disease
A drug and drug delivery system may be utilized in the treatment of vascular disease. A local delivery system is coated with rapamycin or other suitable drug, agent or compound and delivered...
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7288084 |
Drug-loaded medical device
A medical device is designed to be placed in a patient's body and release one or more therapeutic agents therefrom. The medical device includes an elongated member defining a passage for passing...
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7252838 |
Drug releasing elastic band and method
A ligating band according to the present invention comprises an elastomeric layer and an inner drug releasing layer. The inner drug releasing layer includes a therapeutic agent, for example a...
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7226978 |
Techniques to improve polyurethane membranes for implantable glucose sensors
The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the...
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7176256 |
Biocompatible crosslinked composition
Crosslinked polymer compositions comprise a first synthetic polymer containing multiple nucleophilic groups covalently bound to a second synthetic polymer containing multiple electrophilic groups....
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7176221 |
Low dose pharmaceutical composition having uniform drug distribution and potency
A method for manufacturing a pharmaceutical composition having uniform drug distribution and potency is described which utilizes silicon dioxide to reduce the loss of active ingredient during the...
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7173102 |
Facially amphiphilic polymers as anti-infective agents
Facially amphiphilic polymers and articles made therefrom having biocidal surfaces are disclosed. The polymers can inhibit the growth of microorganisms in contact with the surface or in areas...
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7172765 |
Biodegradable and/or bioabsorbable fibrous articles and methods for using the articles for medical applications
Biodegradable and/or bioabsorable fibrous articles and methods for using the articles in medical applications are disclosed. The biodegradable and/or bioabsorable fibrous articles, which are formed...
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7166605 |
Probucol nitro-derivatives
Probucol derivatives and pharmaceutical compositions containing the same to be employed in treatment or prophylaxis of diseases.
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7166299 |
Preparation of aqueous clear solution dosage forms with bile acids
Compositions for pharmaceutical and other uses comprising clear aqueous solutions of bile acids which do not form any detectable precipitates over selected ranges of pH values of the aqueous...
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7163688 |
Osmotic implant with membrane and membrane retention means
An osmotic delivery system for controlled delivery of a beneficial agent includes an implantable capsule containing a beneficial agent and an osmotic engine that swells on contact with water,...
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7163674 |
Personal care compositions comprising a dicarboxy functionalized polyorganosiloxane
Disclosed are personal care or cosmetic compositions comprising a dicarboxy functionalized polyorganosiloxane and methods for the cleaning or the treatment of hair or skin and for enhancing...
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7160921 |
Reduction of hair growth
Mammalian hair growth can be reduced by topical application of an inhibitor of fatty acid metabolism.
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7160551 |
Injectable system for controlled drug delivery
An injectable composition for delivery of a bioactive agent contains a biocompatible solvent, a hydrophobic polymer, and an amphiphilic block copolymer. The hydrophobic polymer may be a...
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7156049 |
Release mechanism to interact with biota, in particular fauna that may outgrow available habitat
A device for interacting with biota either on a pre-specified schedule or via actuation by remote signal. Preferably, the biota are fauna and more particularly fish. In selected embodiments, it...
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7117870 |
Lacrimal insert having reservoir with controlled release of medication and method of manufacturing the same
A lacrimal insert includes a body defining a reservoir, and a head provided at an end of the body and closing the reservoir. The body is made from a material impermeable to the medication while the...
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7112417 |
Foam composite for the repair or regeneration of tissue
The present patent describes a biocompatible composite made of a first fibrous layer attached to a three-dimensional inter-connected open cell porous foams that have a gradient in composition...
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7112335 |
Minimally compliant, volume-efficient piston for osmotic drug delivery systems
An osmotic pump having a minimally compliant, volume-efficient piston positioned within a capsule is provided. The capsule has an interior surface, a beneficial agent, and an osmotic agent. The...
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7109255 |
Bioresorbable hydrogel compositions for implantable prostheses
Crosslinked compositions formed from water-insoluble copolymers are disclosed. These compositions are copolymers having a bioresorbable region, a hydrophilic region and at least two cross-linkable...
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7108862 |
Bone growth compositions and methods
The present invention provides an improved technique for spinal fusion involving the administration of an HMG-CoA reductase inhibitor to a fusion. The HMG-CoA reductase inhibitor is preferably...
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7105175 |
Implantable or insertable medical devices for controlled delivery of a therapeutic agent
The present invention is directed to novel implantable or insertable medical devices that provide controlled release of a therapeutic agent. According to an embodiment of the present invention, a...
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7101394 |
Energetically-controlled delivery of biologically active material from an implanted medical device
A medical device and system capable of providing on-demand delivery of biologically active material to a body lumen patient, and a method of making such medical device. A first coating layer...
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7097855 |
Transdermal thermal polymerization
An invention for polymerizing or crosslinking a prepolymer using a water soluble, thermal polymerization initiator is disclosed. The prepolymer mixed with the initiator is injected or placed into...
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7094419 |
Method of obtaining immune cells from an animal
The present invention is directed to an implantable immune modulation device that is useful for modulating an immune response in mammals, comprising a plurality of fibers, within a porous shell....
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7094230 |
Systems and methods for delivering drugs to selected locations within the body
An implantable reservoir device ( 400 ) including an enclosed membrane ( 408 ) on an expandable frame ( 402 ) that defines a reservoir ( 410 ) and includes a porous region ( 418 ). The reservoir...
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7074430 |
Controlled release tramadol tramadol formulation
A controlled release preparation for oral administration contains tramadol, or a pharmaceutically acceptable salt thereof, as active ingredient.
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7074425 |
Hemostatic compositions and methods
The present invention provides methods and compositions involving resorbable hemostatic agents that have the essential absence of microfibrillar collagen. Resorbable hemostatic agents of the...
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7070809 |
Hydrogel biomedical articles
Hydrogel biomedical articles formed from macromers having a polymeric backbone comprising 1,2-diol and/or 1,3-diol units, such as polyvinyl alcohol, and pendant chains bearing crosslinkable groups...
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7060288 |
Biomedical devices
The present invention is concerned with biomedical device comprising
(a) a biocompatible organic or inorganic bulk material and (b) a coating comprising polymerizable carbon-carbon double...
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7056726 |
membrane for encapsulation chamber of cells producing at least a biologically active substance and bioartificial organ comprising same
The invention concerns a semipermeable chamber for encapsulation of cells producing at least a biological substance of interest, characterised in that it consists of a porous polycarbonate...
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