Matches 201 - 250 out of 470 < 1 2 3 4 5 6 7 8 9 10 >
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6001387 Spin disk encapsulation apparatus and method of use  
An encapsulating apparatus comprising a spinning cup adjustably rotatable about its central axis for forming droplets and projecting them radially outward, and one or more collection basins...
5985328 Micromachined porous membranes with bulk support  
A microfabricated containment capsule has a bulk substrate delimiting a cavity with a boundary, a first portion of which constitutes an inner wall of a solid portion of the bulk substrate. The bulk...
5980927 Method and apparatus for administering analgesics, and method for making same device  
A device and method is disclosed for continuously administering an analgesic to the neuraxis of an organism. The device comprises a polymeric matrix body loaded with the analgesic. The body is...
5980973 Implantable medical device with biocompatible surface and method for its manufacture  
A method of providing biocompatible surface texturing on a metal component of an implantable device and the device so produced. The coating is provided by applying particles of metal falling...
5976780 Encapsulated cell device  
A macroencapsulation device for somatic cells using ultrapurified Na alginate and polysulfone hollow fibers of 30 kDa molecular weight cutoff. Ultrapurified Na alginate material is used which has a...
5972370 Peptide/protein suspending formulations  
The present invention provides improved compositions for improving the chemical and physical stability of peptides and proteins. The invention provides a liquid beneficial agent formulation...
5972366 Drug releasing surgical implant or dressing material  
A surgical implant or external wound dressing which functions as both a hemostat and a device to safely and effectively deliver any of a number of pharmaceuticals to targeted tissue at a controlled...
5972369 Diffusional implantable delivery system  
A sustained release delivery system for delivering a beneficial agent is provided. The system includes a reservoir comprising the beneficial agent and a capillary channel in communication with the...
5968004 Microporous membrane sheet plasma extraction catheter  
An assembly for being implanted in a blood vessel for carrying out in vivo plasma separation incorporates a plasma extraction capsule formed of a microporous polymeric membrane sheet having a pore...
5968096 Method of repairing perforated submucosal tissue graft constructs  
A perforated unitary multi-laminar tissue graft construct and method for preparing such construct is described. The method comprises overlapping strips of submucosa tissue with other strips of...
5964804 Close vascularization implant material  
A device for implantation in a host having a material at an interface between the host and the device, said material having a conformation which results in growth of vascular structures by the host...
5965276 Method of forming a membrane especially a latex or polymer membrane including multiple discrete layers  
Single and multiple layer membranes such as gloves and condoms include one or more deactivating barrier layers and/or indicating layers to indicate to a user membrane breach or the presence of a...
5964261 Implantation assembly  
An implant assembly and methods for loading implant devices which avoids the accidental deposition of transplanted material or other contaminates on the exterior of the device during...
5962005 Transparent cellulose hydrogel and production process thereof  
A transparent cellulose hydrogel having a transmittance of visible light of not less than 70%/mm and a tensile strength of not less than 10 kg/cm 2 , wherein the hydroxyl groups of cellulose...
5945115 Polymeric compositions useful as controlled release implants  
The invention is directed to an improved system for controlled release of biologically active materials and to a liquid composition for its formation. The liquid composition is composed of a...
5938923 Microfabricated filter and capsule using a substrate sandwich  
A microfabricated filter made up of two bonded substrate structures, each consisting of single crystalline silicon can optionally be formed into a capsule. The pores of the filter consist of one or...
5922339 Compositions and methods for biocompatible implants  
Methods and compositions for preventing an immune response in a mammal having an implanted transplant are provided. The compositions comprise non-immunogenic aromatic chains with interspersing...
5916554 Use of pouch for implantation of living cells  
A biocompatable and biostable flexible pouch for use e.g., in implanting cell bodies producing therapeutic agents, featuring, in various aspects, either encapsulated or unencapsulated cell bodies...
5913998 Method of making an implantable containment apparatus for a therapeutical device  
This invention relates generally to an implantable containment apparatus made of selectively permeable material. In particular, the implantable containment apparatus is used to contain a...
5912005 Methods of use of uncoated gel particles  
The invention covers a method of implanting a living donor cell into a host animal without inflammatory response or rejection of the donor cell by the host animal, by obtaining an uncoated particle...
5910315 Allograft tissue material for filling spinal fusion cages or related surgical spaces  
An extrudable allograft bone tissue material for filling surgical sites can be made from mineralized or demineralized cortical, cancellous, or cortical/cancellous bone powder. A method is disclosed...
5908633 Bioartificial hormone releasing device  
A device for the effective release of hormones wherein a matrix containing a hormone producing cellular moiety is encapsulated with a non-immunogenic polymeric material of poly-para-xylyene having...
5902745 Cell encapsulation device  
The present invention is directed to a cell encapsulation device that permits rapid and straightforward cell transfer into the device. The preferred device includes components that allow a user to...
5902577 Insulin-secreting cell lines, methods of production and use  
The invention relates to the field of biology and, in particular, to the field of cellular biology. The invention concerns a novel glucose-sensitive cell line designated β cell line (INS-I)...
5902598 Sustained release drug delivery devices  
A method and device for treating a mammalian organism to obtain a desired local or systemic physiological or pharmacological effect is provided. The method includes administering a sustained...
5900408 Methods of creating a unique chitosan and employing the same to form complexes with drugs, delivery of the same within a patient and a related dosage form  
A method of creating a unique deacetylated, depolymerized chitosan which may be employed to provide a time release chitosan-drug complex. The chitosan is deacetylated at least 60 percent and...
5893839 Timed-release localized drug delivery by percutaneous administration  
Devices and methods are disclosed for the percutaneous administration of a composition to a desired in vivo location. The composition comprises a biologically active substance and a...
5893974 Microfabricated capsules for immunological isolation of cell transplants  
The present invention provides a capsule made of a biologically compatible material with sufficient mechanical strength to form a very thin membrane shell having at least a region with...
5891455 Process for producing an implant from cell cultures  
In a process for producing an implant from cell cultures in vitro, tissue cells, particularly cartilage cells, are introduced into a three-dimensional self-supporting structure preformed preferably...
5888988 Covalently linked N,O-carboxymethylchitosan and uses thereof  
Covalent compositions of N,O-carboxymethyl chitosan (NOCC) are disclosed. NOCC can be intra- or intermolecularly linked, either through a direct bond or through a bridging moiety. Also disclosed...
5876452 Biodegradable implant  
Biodegradable, porous, polymeric implant material provides substantially continuous release of bioactive agent during in vivo use. Bioactive agent is initially released in amounts that are less...
5876742 Biological tissue transplant coated with stabilized multilayer alginate coating suitable for transplantation and method of preparation thereof  
A biological tissue transplant coated with a stabilized multilayer alginate coating and a method for preparation of the stabilized multilayer coating. Coating has three primary layers of the...
5874099 Methods for making immunoisolatary implantable vehicles with a biocompatible jacket and a biocompatible matrix core  
A method of forming an implantable and retrievable immunoisolatory vehicles is disclosed, the method comprising the steps of first forming a core comprising a volume of at least 1 μl and at least...
5871767 Methods for treatment or prevention of neurodegenerative conditions using immunoisolatory implantable vehicles with a biocompatible jacket and a biocompatible matrix core  
A method for treatment of a neurodegenerative condition in a patient comprising implanting in the patient at least one immunoisolatory vehicle comprising a corc comprising a volume of at least 1...
5871472 Planting devices for the focal release of neuroinhibitory compounds  
Methods are disclosed for the alleviation of movement disorders via the implantation of static devices which focally release neuroinhibitory compounds to preselected brain areas. Pathological...
5868142 Implantable device  
The invention refers to a solution of the problem to induce alcoholics or other drug abusers to refrain from alcohol or other drug during a longer period of time. Thus it consists of an implantable...
5869077 Methods for treating diabetes by delivering insulin from biocompatible cell-containing devices  
A method for treating diabetes in a patient comprising subcutaneously implanting in the patient at least one immunoisolatory vehicle comprising a core comprising a volume of at least 1 μl and at...
5861168 Intramural delivery of nitric oxide enhancer for inhibiting lesion formation after vascular injury  
Vessels suffering vascular injury from angioplasty are treated with L-arginine intramurally. The incidents associated with restenosis are substantially reduced providing for a reduced incidence of...
5855904 Biodegradable sustained release preparation for treating periodontitis  
The present invention relates to a biodegradable sustained release preparation for treating periodontitis, especially containing polysaccharide. The core of the preparation according to the present...
5856367 Biocompatible porous matrix of bioabsorbable material  
A process for forming biocompatible porous matrices of bioabsorbable materials comprising: a) providing a bioabsorbable polymer; b) dissolving the bioabsorbable polymer in a volumetric...
5855616 Bioartificial pancreas  
An implantable bioartificial pancreas device having an islet chamber containing glucose responsive and insulin-secreting islets of Langerhans or similar hormone secreting cells, one or more...
5853745 Medical implant having a durable, resilient and effective antimicrobial coating  
A medical implant, such as an orthopedic implant, having a first antimicrobial coating layer and a second protective layer, and a method for coating such an implant is provided. The medical implant...
5851547 Controlled release drug formulation of open end cylindrical rod form  
A drug formulation for producing sustained therapeutic efficacy, which releases at least one water-soluble drug over a prolonged period of time at a substantially constant rate wherein said drug...
5843781 Implantable prosthetic vascular device having an adherent cell monolayer produced under shear stress  
A device having a surface coated with a firmly adherent cell monolayer is produced by culturing adherent cells in the presence of the surface in vitro under conditions of continuous shear stress of...
5840325 Osteogenic devices  
Disclosed are osteogenic devices comprising a matrix containing substantially pure mammalian osteogenic protein and methods of inducing endochondral bone growth in mammals. A partial amino acid...
5836935 Implantable refillable controlled release device to deliver drugs directly to an internal portion of the body  
An implantable, refillable, rate-controlled drug delivery device, with a hollow reservoir, and a drug delivery tube communicating with the hollow reservoir. The drug delivery tube includes at least...
5837234 Bioartificial organ containing cells encapsulated in a permselective polyether suflfone membrane  
A bioartificial organ for implanting to provide a therapeutic effect is prepared containing a core of living cells encapsulated in a foam-like membrane having three regions: a dense, fine-pored,...
5834001 Methods for making immunoisolatory implantable vehicles with a biocompatiable jacket and a biocompatible matrix core  
A method of forming an implantable and retrievable immunoisolatory vehicle is disclosed, the method comprising the steps of first forming a jacket of biocompatible thermoplastic or hydrogel, and...
5834005 Bioartificial devices and cellular matrices therefor  
A device for the effective release of cellular moieties, including hormones, wherein a matrix containing a hormone producing cellular moiety is encapsulated with a non-immunogenic polymeric...
5827707 Method for manufacturing minimal volume capsules containing biological materials  
The present invention provides methods and a device for producing minimal volume capsules containing viable cells or cellular aggregates. The methods and device use a two-phase aqueous emulsion...
Matches 201 - 250 out of 470 < 1 2 3 4 5 6 7 8 9 10 >