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8911492 Coating for a medical device having an anti-thrombotic conjugate  
An implantable device having a coating comprising a comb-type anti-thrombotic conjugate to prevent or reduce the formation of thrombosis on the surface of the device. The device includes a frame...
8911761 Composite materials  
This application discloses a composite material comprising one or more silk elements in an acrylic or cross-linked protein matrix. The silk elements are made from the group of silk elements...
8911789 Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom  
Blood-derived plastic articles prepared from compositions including blood and, in some embodiments, at least one crosslinking agent and/or at least one biological response modifier, that can be...
8911762 Polylactic acid/calcium sulfate scaffold  
The invention relates to a method of preparing a composite or porous composite used as a biodegradable scaffold, the composite prepared therefrom and the use of the composite. In particular, the...
8906362 Tissue engineered meniscus scaffolds and methods of use  
Provided herein are methods of producing a meniscus scaffold to remove material and increase the pore size and porosity therein. In some embodiments, methods include seeding the tissue with...
8906394 Hyaluronic acid based copolymers  
Hyaluronic acid (HA) conjugates or crosslinked HAs compositions for coating an implantable device are provided. The implantable device can be used for treating a disorder such as atherosclerosis,...
8906402 System and method for attaching soft tissue to an implant  
One embodiment of the present invention is directed to compositions and methods for enhancing attachment of soft tissues to a metal prosthetic device. In one embodiment a construct is provided...
8906111 Artificial bone material having controlled calcium ion elution  
Disclosed is an artificial bone material having controlled calcium ion elution, which does not induce cytotoxicity or any inflammatory response. It is found that the elution of a calcium ion from...
8906686 Method for preparation of implantable constructs  
Neo-cartilage constructs suitable for implantation into a joint cartilage lesion in situ and a method for repair and restoration of function of injured, traumatized, aged or diseased cartilage. The...
8905032 Occlusion of fallopian tubes in a vertebrate subject  
According to one claim of the invention, a method for occluding a fallopian tube in a vertebrate subject is described, which comprises comprising transcervically delivering a solid blocking...
8906401 Antimicrobial medical devices containing chlorhexidine free base and salt  
The present disclosure invention relates to medical devices treated with a solution comprising one or more solvents and a combination of chlorhexidine free base and a water-soluble chlorhexidine...
8900617 Bio-Remodable Bone Augmentation device and method  
A bio-remodable augmentation device including an implantable member configured for maintaining space in a bone defect. The implantable member is formed from a bio-remodable composite having...
8900640 Expandable, porous apatite/collagen composite, and its production method  
A expandable porous body constituted by a compressed apatite/collagen composite, which expands by water absorption, and a method for producing an expandable, porous apatite/collagen composite,...
8900556 Hardenable thermally responsive compositions  
Thermally responsive compositions that include a thermally responsive viscosity modifier, a polymerizable component, and water are provided. The compositions, which optionally may be hardened, are...
8900620 Drug-impregnated encasement  
A drug-impregnated sleeve for encasing a medical implant is provided. In one embodiment, the sleeve may include a body made of a biologically-compatible material that defines an internal cavity...
8900616 System and method for satellite drug delivery  
The present disclosure is directed to an implantable repository including a housing comprising at least one bioactive agent and at least one attachment member coupled to the housing, the at least...
8895048 Templated islet cells and small islet cell clusters for diabetes treatment  
Substrates and devices for culturing cells are disclosed, along with methods of using the same. The substrates and devices include top surfaces with one or more divots disposed therein. Each divot...
8895506 Protein stabilization formulations  
The present invention is directed to stabilizing Bone Morphogenetic Protein in various lyophilized formulations and compositions. The present invention comprises formulations primarily including...
8895046 Orthopaedic implant for supporting tissue growth and methods of forming the implant and tissue  
Adult autologous stem cells cultured on a porous, three-dimensional tissue scaffold-implant for bone regeneration by the use of a hyaluronan and/or dexamethasone to accelerate bone healing alone or...
8895304 Hemostatic device  
A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce hemostasis at an anatomical site.
8895047 Combined fibrinolytic and antimicrobial catheter and uses thereof  
Implantable catheters are provided which comprise an antimicrobial agent incorporated in a coating or bulk distributed, in combination with a fibrinolytic agent incorporated in a top coating.
8895049 Extended release biodegradable ocular implants  
Biodegradable implants sized and suitable for implantation in an ocular region or site and methods for treating ocular conditions. The implants provide an extended release of an active agent at a...
8889823 Method to make poly(L-lactide) stent with tunable degradation rate  
Methods of making a biodegradable polymeric stent made from poly(L-lactide) and a low concentration of L-lactide monomer is disclosed. The concentration of L-lactide is adjusted to provide a...
8889169 Drug delivery system and method of manufacturing thereof  
Irradiation of a surface of a material with a gas cluster ion beam modifies the wettability of the surface. The wettability may be increased or decreased dependent on the characteristics of the gas...
8889211 Coating process for drug delivery balloons using heat-induced rewrap memory  
A method of producing a drug coated balloon that comprises the steps of: subjecting a balloon catheter with a folded and wrapped balloon thereon to a pre-annealing step to induce a fold/wrap memory...
8889178 Bioactive porous bone graft compositions in synthetic containment  
Bioactive porous bone graft implants in various forms suitable for use in bone tissue regeneration and/or repair, as well as methods of use are provided. The implants are formed of bioactive glass...
8889168 Stem cell capture and immobilization coatings for medical devices and implants  
Constructs and methods for immobilizing stem and other precursor cells, as well as other bioactive materials of therapeutic value on the surfaces of medical devices, such as bone, cartilage, spinal...
8888840 Drug eluting medical implant  
Disclosed are self-expanding medical implants for placement within a lumen of a patient. The implants comprise a woven or non-woven structure having a substantially tubular configuration, and are...
8889170 Implantable device having a coating with a triblock copolymer  
The present invention provides an implantable device having a coating including a slow dissolving polymer or material and the methods of making and using the same.
8883182 Method and material for enhanced tissue-biomaterial integration  
The present invention provides a composition and method for the covalent binding of a hydrogel to an extracellular matrix (ECM). Therapeutic applications include tissue repair and delivery of drugs...
8883175 Block copolymers of acrylates and methacrylates with fluoroalkenes  
A block copolymer comprising a fluorinated block and a non-fluorinated block and method of making the block copolymer are provided. Also provided herein are a coating on an implantable device...
8883184 Methods and compositions for regenerating connective tissue  
Connective tissue regenerative compositions and methods of repairing and regenerating connective tissue using such compositions are provided. The compositions generally comprise a bioactive...
8883186 Coatings for drug delivery devices  
A polymer coating for medical devices based on a polyolefin derivative. A variety of polymers are described to make coatings for medical devices, particularly, for drug delivery stents. The...
8883183 Medical devices incorporating collagen inhibitors  
Provided herein are implantable or insertable biomedical devices comprising a substrate and a collagen inhibitor on or in said substrate, and methods of treatment using the same. In some...
8883195 Bioactive porous bone graft implants  
Bioactive porous bone graft implants in various forms suitable for bone tissue regeneration and/or repair, as well as methods of use, are provided. The implants are formed of bioactive glass and...
8883185 Hydrogel implants with varying degrees of crosslinking  
The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors...
8877508 Devices and systems that deliver nitric oxide  
The present disclosure relates to dressings, such as patches and bandages, and other devices and systems that deliver nitric oxide.
8877233 Porous sponge matrix medical devices and methods  
Described are hemostasis devices useful for implantation in biopsy tracts, which device comprise highly compact, dried hemostatic sponge elements. Preferred devices also include compacted sponge...
8877225 Controlled release copolymer formulation with improved release kinetics  
The present invention provides a constant release copolymer composition adapted for use in a controlled release formulation for a bioactive agent, such as a formulation adapted for implantation...
8876860 Vascular closure device  
The present invention provides a porous structure that works very effectively to seal a puncture site with optimum porosity, absorbent capacity and perfect anatomical fit. The plug density and...
8877224 Compositions for preventing cardiac arrhythmia  
Disclosed herein are compositions and methods for treating or preventing a cardiac arrhythmia in a subject.
8877170 Medical device with inflammatory response-reducing coating  
The present disclosure relates to implantable medical devices having a non-bioabsorbable substrate and an amphiphilic coating covalently bonded to the substrate for reducing the inflammatory...
8877223 Degradable hydrophilic block copolymers with improved biocompatibility for soft tissue regeneration  
The present application discloses biodegradable polymers, to porous and other materials comprising such polymers, and to various medical uses of such materials, including use as a scaffold for...
8871239 Polymeric materials for medical devices  
The present invention includes biocompatible polymeric coatings, membranes, matrices, and films to be used with implantable medical devices. Medical devices containing such materials applied to a...
8871238 Medical devices and coatings therefore comprising biodegradable polymers with enhanced functionality  
Biodegradable polymers useful for fabricating implantable medical devices and as coatings for medical devices are provided. The biodegradable polymers are biocompatible and can be tuned to provide...
8871267 Protein matrix materials, devices and methods of making and using thereof  
The present invention relates to protein matrix materials and devices and the methods of making and using protein matrix materials and devices. More specifically the present invention relates to...
8870945 Bioabsorbable device having composite structure for accelerating degradation  
A medical device has a structure made of a first biodegradable and/or bioabsorbable material and a second biodegradable and/or bioabsorbable material encapsulating a degradation additive...
8871240 Rapamycin coated expandable devices  
Medical devices may be utilized for local and regional therapeutic agent delivery. These therapeutic agents or compounds may reduce a biological organism's reaction to the introduction of the...
8871511 Method for treatment of cardiovascular disorders  
Methods for treating a cardiovascular disorder comprising concomitant administration of one or more extracellular matrix (ECM) based compositions directly to damaged or diseased cardiovascular...
8874204 Implantable medical devices comprising isolated extracellular matrix  
Implantable devices containing extracellular matrix and methods of using the devices are provided.