|
Match
|
Document |
Document Title |
|
|
8465582 |
Process for producing inorganic interconnected 3D open cell bone substitutes
The present invention relates to a process of using a heat responsive mixture to produce inorganic interconnected 3D open-cell bone substitutes which can be applied in the orthopedic or dental...
|
|
|
8460695 |
Making a soft tissue prosthesis for repairing a defect of an abdominal wall or a pelvic cavity wall
Surgical prostheses and methods of using and making surgical prostheses are disclosed.
|
|
|
8460694 |
Solvent/polymer solutions as suspension vehicles
A nonaqueous, single-phase vehicle that is capable of suspending an active agent. The nonaqueous, single-phase vehicle includes at least one solvent and at least one polymer and is formulated to...
|
|
|
8460646 |
Methods and compositions for treating mammalian nerve tissue injuries
To achieve, an in vivo repair of injured mammalian nerve tissue, an effective amount of a biomembrane fusion agent is administered to the injured nerve tissue. The application of the biomembrane...
|
|
|
8460274 |
Long term drug delivery devices with polyurethane-based polymers and their manufacture
This invention is related to the use of polyurethane-based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods...
|
|
|
8460693 |
Intraluminal device with a coating containing synthetic fish oil and a therapeutic agent
The invention relates to an intraluminal device, in particular an intraluminal prosthesis, shunt, catheter or local drug delivery device. In order to increase the bio-compatibility of this device,...
|
|
|
8460378 |
Biocompatible, biodegradable polyurethane materials with controlled hydrophobic to hydrophilic ratio
The biocompatible, biodegradable materials in the solid and/or liquid form are based on segmented linear polyurethanes and/or segmented crosslinked polyurethanes based on A) one or more...
|
|
|
8455008 |
Processed ECM materials with enhanced component profiles
Described are medical graft materials and devices having improved properties relating to their component profiles.
|
|
|
8455464 |
Dextrin containing compositions for prevention of adhesions
A composition for the treatment of adhesions that are formed as a result of an inflammatory response comprising an aqueous formulation containing the polysaccharide dextrin in an effective amount....
|
|
|
8450455 |
cRGD peptide derivative and its manufacture, and implant having a coating containing a cRGD peptide derivative
Various embodiments of the invention relate to a cRGD peptide derivative and an associated manufacturing method, and to an implant having a coating containing a cRGD peptide derivative. One aspect...
|
|
|
8449901 |
Implantable medical device with beneficial agent concentration gradient
The implantable medical devices are configured to release at least one therapeutic agent from a matrix affixed to the implantable body with a release profile which is programmable to the agent and...
|
|
|
8449903 |
Crosslinked bioabsorbable medical devices
The present invention is directed to bioabsorbable medical devices which are introduced into the body of a subject in a first configuration and deformed in the subject's body to a second...
|
|
|
8449904 |
Bioactive glass scaffolds, and method of making
A glass, glass-ceramic, or ceramic bead is described, with an internal porous scaffold microstructure that is surrounded by an amorphous shield. The shield serves to protect the internal porous...
|
|
|
8449902 |
Methods for producing biomaterials with variable stiffness
This invention relates to the production of biomaterials with variable stiffness by subjecting a gel which varies in at least one dimension to plastic compaction. These biomaterials may be useful,...
|
|
|
8445006 |
Biomolecular coating for implants
Methods and compositions are provided for improving tissue growth and device integration in vivo. Substrates and devices coated with an α2β1 or α5β1 integrin-specific ligand are provided. The sub...
|
|
|
8445008 |
Reduction of infection associated with medical device
Anti-infective articles capable of preventing infection associated with implantation of medical devices include low levels of anti-infective agents, may cover only a fraction of the portion of the...
|
|
|
8440215 |
Absorbable polymer formulations
A co-polyester which includes the reaction product of a polycondensation polyester and epsilon-caprolactone, wherein the polycondensation polyester comprises the reaction product of diglycolic acid...
|
|
|
8440737 |
Composition for injectable cement useful as bone replacement
The invention relates to a composition for injectable cement, comprising a mineral sold phase, a separate liquid phase and, optionally, microparticles of a biocompatible and biodegradable polymer....
|
|
|
8440618 |
Composition for the attachment of implants to collagen or other components of biological tissue
The present invention relates to a novel composition comprising an implant, scaffold or construct bound to a biological or chemical moiety. The bound moiety has the ability to bind to a component...
|
|
|
8435550 |
Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device
A drug-delivery system is provided including at least 100 μg of everolimus and clobetasol, such that the ratio of everolimus to clobetasol is at least 10:1 (w/w) or the amount of everolimus by ...
|
|
|
8435552 |
Collagen/hydroxyapatite composite scaffold, and process for the production thereof
A process for producing a collagen/hydroxyapatite (HA) composite scaffold comprises the steps of forming a homogenous suspension of collagen and HA in an acidic solution, lyophilizing the...
|
|
|
8435551 |
Cancellous construct with support ring for repair of osteochondral defects
The invention is directed toward an osteochondral repair assembly comprising a shaped allograft construct comprising an unbalanced barbell-shaped cylindrical cancellous bone primary member formed...
|
|
|
8435943 |
Protein stabilization formulations
The present invention is directed to stabilizing Bone Morphogenetic Protein in various lyophilized formulations and compositions. The present invention comprises formulations primarily including...
|
|
|
8435553 |
Elastin stabilization of connective tissue
A method and product are provided for the treatment of connective tissue weakened due to destruction of tissue architecture, and in particular due to elastin degradation. The treatment agents...
|
|
|
8435343 |
Bone graft material and uses thereof
Bone graft compositions for repairing bone defects, which are characterized by a chemical composition of cementitious, non-cementitious, highly-resorbable and poorly-resorbable particulate...
|
|
|
8431665 |
Zwitterionic terpolymers, method of making and use on medical devices
Biocompatible terpolymers are manufactured to include a zwitterionic monomer, an alkoxy acrylate monomer, and a hydrophobic monomer.
|
|
|
8431147 |
Malleable implants containing demineralized bone matrix
Described are malleable medical compositions such as pastes or putties that include solids combined with a liquid carrier. The solids include particulate collagen and particulate demineralized bone...
|
|
|
8431146 |
Scaffold comprising co-precipitated Collgen and glycosaminoglycan for inhibiting adhesion of body tissue layers
A device for inhibiting adhesion of apposing human body tissue layers includes a scaffold having a designated mean pore size, relative density, and degradation half-life. The scaffold may be...
|
|
|
8426486 |
Highly crystalline cross-linked oxidation-resistant polyethylene
The present invention relates to methods for making highly crystalline cross-linked polymeric material, for example, highly crystalline cross-linked ultra-high molecular weight polyethylene...
|
|
|
8425927 |
Compositions and methods for coating medical implants
Medical implants are provided which release an anthracycline, fluoropyrimidine, folic acid antagonist, podophylotoxin, camptothecin, hydroxyurea, and/or platinum complex, thereby inhibiting or...
|
|
|
8425815 |
Highly crystalline polyethylene
The present invention relates to methods for making highly crystalline polymeric material, for example, highly crystalline cross-linked and not cross-linked ultra-high molecular weight polyethylene...
|
|
|
8425926 |
Antimicrobial medical devices
The present invention provides methods for making an antimicrobial medical device, preferably an antimicrobial ophthalmic device, more preferably an antimicrobial extended-wear contact lens, which...
|
|
|
8420000 |
Highly crystalline polyethylene
The present invention relates to methods for making highly crystalline polymeric material, for example, highly crystalline cross-linked and not cross-linked ultra-high molecular weight polyethylene...
|
|
|
8420111 |
Method and kit for reducing the symptoms of peripheral vascular disease
A method for reducing the symptoms of peripheral vascular disease and for improving peripheral circulation wherein a progestin is administered to a subject in need thereof.
|
|
|
8419803 |
Calcium phosphate cements and methods for using the same
Methods and compositions for producing flowable compositions, e.g. pastes, that set into calcium phosphate products are provided. In the subject methods, dry reactants that include a calcium source...
|
|
|
8420077 |
Silk fibroin hydrogels and uses thereof
The present specification provides for methods for purifying fibroins, purified fibroins, methods of conjugating biological and synthetic molecules to fibroins, fibroins conjugated to such...
|
|
|
8420110 |
Drug coated expandable devices
Medical devices may be utilized for local and regional therapeutic agent delivery. These therapeutic agents or compounds may reduce a biological organism's reaction to the introduction of the...
|
|
|
8414909 |
Drug releasing coatings for medical devices
The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a...
|
|
|
8414907 |
Coatings on medical implants to guide soft tissue healing
Embodiments include coatings or surface treatments for medical instruments, devices, and/or implants that promote soft tissue healing. More particularly, embodiments relate to treating portions of...
|
|
|
8414908 |
Compositions comprising nanostructures for cell, tissue and artificial organ growth, and methods for making and using same
The invention provides articles of manufacture comprising biocompatible nanostructures comprising nanotubes and nanopores for, e.g., organ, tissue and/or cell growth, e.g., for bone, kidney or...
|
|
|
8414526 |
Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids
The invention relates to a coated medical device for rapid delivery of a therapeutic agent to a tissue in seconds to minutes. The medical device has a layer overlying the exterior surface of the...
|
|
|
8414910 |
Drug releasing coatings for medical devices
The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a...
|
|
|
8414873 |
Blood vessel stent of amidoglucosan polysaccharide loaded with CD133 antibody and its preparation method
A blood vessel metal stent coating of amidoglucosan polysaccharide loaded with antibody comprises carrier material composed of chitosan and inartificial degradable acidic amidoglucosan...
|
|
|
8415406 |
Setting time indicator for acrylic bone cement
A bone cement has a liquid acrylic monomer component, a powdered acrylic polymer component and yellowish beta-carotene (Pro-vitamin A) mixed into one of the liquid or powdered component and FDC...
|
|
|
8414929 |
Medical substitute membrane, use thereof, and method for repair of membrane tissue in living body
The dried amniotic membrane is produced by drying a fresh amniotic membrane, which envelopes an embryo of an animal including human, and can be used as a substitute membrane for a membrane tissue...
|
|
|
8414932 |
Active bromine containing biocidal compositions and their preparation
Described are highly concentrated liquid biocidal solutions formed in water from (a) specified bromine sources (e.g., BrCl or mixtures of BrCl and Br2) and (b) alkali metal salt of sulfamic acid...
|
|
|
8409227 |
Neural implant
The invention relates to a biocompatible neural implant for bridging interruptions or defects in nerves resulting from injuries sustained in an accident or following surgery. Inventive neural...
|
|
|
8409600 |
Methods for prevention and/or treatment of capsular contracture
Methods for prevention or treatment of capsular contracture following surgical implants and other fibrosis related conditions comprising applying a topical composition comprising a pharmaceutically...
|
|
|
8409602 |
Sealants for fetal membrane repair
The present invention provides a method for preventing or repairing damage to a fetal membrane. In one embodiment, the method comprises contacting a fetal membrane with a composition comprising a...
|
|
|
8409603 |
Compositions and methods for tissue engineering, tissue regeneration and wound healing
In accordance with certain embodiments of the present disclosure, a kit is described. The kit includes primed living cells joined to and at least partially within a three-dimensional hydrogel...
|