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7619009 Systems and methods for controlling and forming polymer gels  
In preferred embodiments, the present invention provides methods of controllably making a vinyl polymer hydrogel having desired physical properties without chemical cross links or radiation. The...
7615234 Drug delivery technology  
The invention relates to a novel drug delivery technology. More particularly the invention relates to a method of delivering at least one therapeutic compound or a formulation comprising the at...
7604818 Polymers of fluorinated monomers and hydrocarbon monomers  
A polymer of fluorinated monomers and hydrocarbon monomers is provided. It is also provided a polymer blend that contains a polymer formed of fluorinated monomers and hydrocarbon monomers and...
7604817 Method for promoting growth of tissue  
A device and method for tissue engineering is disclosed. More particularly this invention relates to a bioabsorbable device and a method of its use which promotes controlled new tissue in-growth...
7604816 Bio-absorbable collagen-based wound dressing  
A collagen-based bio-absorbable wound dressing which contains a linear polymer biguanide and/or a water-soluble salt thereof. The biguanide is preferably polyhexamethylene biguanide. The...
7604185 Generation of therapeutic microfoam  
Improved therapeutic sclerosing microfoams and methods and devices for making them are provided that have advantage in producing a consistent profile injectable foam with minimal input by the...
7601383 Coating construct containing poly (vinyl alcohol)  
A method of forming a surface layer that includes a hydroxyl polymer on a substrate coating on a medical device is provided.
7601363 Sustained-release drug formulations  
The present invention relates to a formulation for implantation having a novel constitution, which accomplishes controlled releases of active ingredients. The formulation comprises one of...
7597903 Method and composition for producing catheters with antibacterial property  
A medical device and a method for imparting antibacterial properties to the device, made from hydrophobic polymer, particularly to urinary latex catheters comprises treatment of the device by...
7592017 Resorbable thin membranes  
Resorbable lactide polymer thin membranes are disclosed. The thin membranes are constructed of polylactide resorbable polymers, which are engineered to be absorbed into the body relatively slowly...
7592016 Methods for preparing and using implantable substance delivery devices  
Method for preparing an implantable device for a sustained delivery of a substance within a body of a human or an animal subject, the method including; dissolving a biocompatible polymer in a...
7589070 Surface modification for improving biocompatibility  
A therapeutic delivery system efficiently introduces biologically active molecules to mammalian cells without the use of synthetic polymers or biopolymer coatings. Surface modification of a metal...
7585515 Crosslinkable polymeric materials and their applications  
The present invention relates to a novel composition for dental, orthopedic and drug delivery purpose. Specifically, it relates to composition comprising an admixture of a resorbable bone...
7582309 Cohesive demineralized bone compositions  
Demineralized bone matrix fibers and a demineralized bone matrix composition are provided. The demineralized bone matrix fibers have an average fiber length in the range from about 250 μm to about...
7579077 Nanofiber surfaces for use in enhanced surface area applications  
This invention provides novel nanofiber enhanced surface area substrates and structures comprising such substrates, as well as methods and uses for such substrates.
7576255 Silver-containing compositions, devices, and methods for making  
The present invention comprises methods and compositions for making a silver-containing antimicrobial hydrophilic material. More particularly, the present invention comprises methods and...
7575759 Tissue engineering scaffolds  
The present invention relates to methods and compositions for the production of scaffolds, such scaffolds to be used for a variety of purposes, including tissue engineering. More specifically, the...
7572221 Reconstructing non-cartilage structural defects  
A cartilaginous structural member (CSM) for use in penile reconstruction, for the correction of developmental defects, postoperative reconstruction, and for reconstructive preprosthetic surgery....
7569233 Hybrid biologic-synthetic bioabsorbable scaffolds  
A bioprosthetic device is provided for soft tissue attachment, reinforcement, and or reconstruction. The device comprises a naturally occurring extracellular matrix portion and a synthetic portion.
7563824 Clathrate complexes formed by hyaluronic acid derivatives and use thereof as pharmaceuticals  
A clathrate formed by: a hyaluronic acid derivative (a), a hyaluronic acid derivative (b 1 ) different from (a), and being able to form a clathrate with (a) and/or a component (b 2 ) not containing...
7563454 Coatings for implantable medical devices  
Coatings for implantable medical devices comprising non-fouling moieties or polymers chemically bonded to the surface of the device via chelating structures, and methods of fabricating the coatings...
7560492 Polysulfone block copolymers as drug-eluting coating material  
A polymeric composition comprising a polysulfone polymer and an elastomeric polymer for use as a coating composition for coating an implantable device, such as a DES, and methods of making and...
7560120 Vehicles for delivery of biologically active substances  
A formulation containing one or more biologically active substances dissolved, dispersed, emulsified, or suspended within a vehicle of one or more citric acid esters and/or citric acid ethers....
7556821 Apparatus and method for transdermal delivery of parathyroid hormone agents  
An apparatus and method for transdermally delivering a biologically active agent comprising a delivery system having a microprojection member (or system) that includes a plurality of...
7553913 Random and non-random alkylene oxide polymer alloy compositions  
A polymeric material comprised of (i) at least one random copolymer comprised of ethylene oxide and one or more other alkylene oxide(s) and (ii) at least one non-random polymer comprised of one or...
7550444 Composition and method for preparing biocompatible surfaces  
The invention provides methods and compositions for providing biocompatible surfaces to medical articles. In particular the invention provides biocompatible coatings with heparin activity. In some...
7550152 Tissue graft scaffold made from cholecyst-derived extracellular matrix  
Bioengineered tissue graft scaffolds and method for producing such scaffolds are provided. The scaffolds are useful to replace or repair damaged mammalian tissues and organs.
7547471 Material for implantation  
The present invention relates to a material for implantation, which is characterised in that the surface of the material partially comprises at least one area of an inorganic, catalytical substance...
7547447 Bioartificial lacrimal gland  
The present invention provides a bioartificial lacrimal gland which contains at least one unit that includes (a) a permeable housing having an interior and an exterior; (b) an outlet connecting the...
7547446 Dry hemostatic compositions and methods for their preparation  
Dry cross-linked gelatin compositions are prepared that rapidly re-hydrate to produce gelatin hydrogels suitable as hemostatic sealants. Gelatin is cross-linked in the presence of certain...
7547445 Crosslinkable macromers  
A crosslinkable macromer system and related methods of preparing the system and using the system in the form of a crosslinked matrix between a tissue site and an implant article such as a tissue...
7541047 Method for production of shaped body for treating wounds in milk producing animals  
Water-dispersible or water-soluble polymers, particularly those of the family of compounds comprising the poloxamers or the polyesters or amphiphilic agents (emulsifiers), and also lipophilic...
7541025 Treatment of malignant tumor  
The invention provides a technology which utilizes donor lymphocyte infusion and by which malignant tumor can be treated without causing such an adverse effect as graft versus host disease. Thus, a...
7537780 Method for preparing and implanting a cartilage construct to treat cartilage lesions  
Neo-cartilage constructs for growth and surface coating for the de novo formation of a superficial cartilage layer. A method for generation of the neo-cartilage and the neo-cartilage construct. A...
7537779 Antimicrobial medical devices  
The present invention provides for antimicrobial medical articles prepared by a method comprising treating a surface of the medical article with a solution consisting essentially of one or more...
7534854 Apparatus and method for oxidation and stabilization of polymeric materials  
An apparatus for treating polymeric materials comprises a treatment chamber adapted to maintain a selected atmosphere; a means for supporting the polymeric material within the chamber; and, a...
7534609 Method of expanding undifferentiated hemopoietic stem cells  
A method of expanding undifferentiated hemopoietic stem cells to increase the number of the hemopoietic stem cells is provided. The method comprising: (a) obtaining the undifferentiated hemopoietic...
7531505 Compositions and methods for promoting attachment of cells of endothelial cell lineage to medical devices  
The present invention provides compositions and methods for an improved coating for medical devices. Provided is a biofunctional coating composition comprising at least one binding domain that has...
7531190 Porous ceramic structure containing biologics  
A ceramic scaffold operable to support a defect in bone and a surrounding healthy tissue comprising a ceramic body having a plurality of pores, the pores having a bioactive material incorporated...
7527804 Method for improvement of soft tissue attachment and implants making use of said method  
A method for improving soft tissue attachment which includes the steps of coating a surface of a material, to which surface soft tissue is to be attached, with a coating rich in TiO 2 and/or SiO 2...
7517539 Method of preparing a poorly crystalline calcium phosphate and methods of its use  
The present invention provides a novel process for producing a calcium phosphate cement or filler which hardens in a temperature dependent fashion in association with an endothermic reaction. In...
7514398 Growth factor complex  
An isolated protein complex is provided which includes a growth factor, growth factor binding protein and vitronectin. Preferably, the isolated protein complex includes an insulin-like growth...
7514249 Biomimetic organic/inorganic composites  
The subject invention concerns a composite comprising an organic fluid-swellable, fibrous matrix, such as collagen, and a mineral phase, such as calcium carbonate or phosphate mineral phase, for...
7514248 Process for making organic/inorganic composites  
The subject invention concerns a composite comprising an organic fluid-swellable matrix, such as collagen, and mineral phase, such as calcium carbonate or phosphate mineral phase, for use as a...
7510724 Medical apparatus  
The invention relates to a medical apparatus having a special coating on its surface, notably its surface facing the surroundings. The coating has germ and/or dirt-repellant and/or bactericidal...
7501018 Chemically bonded biomaterial with tailored properties  
A chemically bonded biomaterial element composed of an inorganic cement, exhibiting minimal dimensional changes upon hardening and long-time use, improved mechanical properties and improved...
7498042 Stent for blood vessel and material for stent for blood vessel  
A luminal stent, implanted and implanted and left in the blood vessel, is disclosed. By permitting a stent ( 1 ), formed of a biodegradable polymer material ( 2 ), to be swollen, and by...
7494665 Polymers containing siloxane monomers  
A polymer of siloxanes as flexibility monomers and strength monomers is provided. It is also provided a polymer blend that contains a polymer formed of siloxane monomers and strength monomers and...
7494664 Composite biomaterials  
This invention provides novel composite biomaterials having excellent bioadaptability and bone inductivity and a process for producing the same. The composite biomaterials comprise hydroxyapatite,...
7494482 Methods and apparatus for application of micro-mechanical forces to tissues  
Methods and devices for transmitting micromechanical forces locally to induce surface convolutions into tissues on the millimeter to micron scale for promoting wound healing are presented. These...