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8871239 Polymeric materials for medical devices  
The present invention includes biocompatible polymeric coatings, membranes, matrices, and films to be used with implantable medical devices. Medical devices containing such materials applied to a...
8871238 Medical devices and coatings therefore comprising biodegradable polymers with enhanced functionality  
Biodegradable polymers useful for fabricating implantable medical devices and as coatings for medical devices are provided. The biodegradable polymers are biocompatible and can be tuned to provide...
8871267 Protein matrix materials, devices and methods of making and using thereof  
The present invention relates to protein matrix materials and devices and the methods of making and using protein matrix materials and devices. More specifically the present invention relates to...
8870945 Bioabsorbable device having composite structure for accelerating degradation  
A medical device has a structure made of a first biodegradable and/or bioabsorbable material and a second biodegradable and/or bioabsorbable material encapsulating a degradation additive...
8871240 Rapamycin coated expandable devices  
Medical devices may be utilized for local and regional therapeutic agent delivery. These therapeutic agents or compounds may reduce a biological organism's reaction to the introduction of the...
8871511 Method for treatment of cardiovascular disorders  
Methods for treating a cardiovascular disorder comprising concomitant administration of one or more extracellular matrix (ECM) based compositions directly to damaged or diseased cardiovascular...
8874204 Implantable medical devices comprising isolated extracellular matrix  
Implantable devices containing extracellular matrix and methods of using the devices are provided.
8871237 Medical scaffold, methods of fabrication and using thereof  
Articles of manufacturing comprising electrospun elements having continuous or stepwise gradients of porosity, average pore size, weight per volume and/or of agents for promoting cell colonization,...
8871235 Compositions and their use in bone healing  
The present invention is directed to implantable compositions comprising substantially spherical bioactive glass particles.
8865199 Biomatrix composition and methods of biomatrix seeding  
Apparatus and methods are described for generating autologous tissue grafts, the apparatus including a point of care SVF isolation unit that includes a tissue digestion chamber in fluid...
8858978 Heat cured gel and method of making  
A method of curing and corresponding resulting non-polymeric cross-linked gel are provided. The cross-linked gel can be combined with a medical device structure. The cross-linked gel can provide...
8858983 Antioxidants and antimicrobial accessories including antioxidants  
An antimicrobial accessory may include a polymer an antimicrobial mixed in the polymer, and an antioxidant. The antioxidant may include, for example, at least one of citric acid, maltol, kojic...
8858982 Apparatus and methods for preventing or treating failure of hemodialysis vascular access and other vascular grafts  
This invention is a prosthetic device generally placed on the outside surface of the vessel or graft which then elutes antiproliferative drugs or agents from a drug-eluting matrix material. Methods...
8858979 Service induced byproducts for localized drug delivery in orthopaedic implants  
A composite material including ultra-high molecular weight polyethylene in conjunction with a biologically active agent is described. The biologically active agent can be, for example, an...
8858929 Optically sensitive cell network  
A neural network is disclosed. The neural network comprises a plurality of optogenetically modified neural cells being three-dimensionally distributed in a hydrogel medium and being disconnected...
8858980 Synthetic mechanical hemostatic composition, method of making and use thereof  
A biocompatible, polymeric composition is disclosed. The composition comprises a base polymer comprising (i) a prepolymer comprising para-dioxanone (PDO) and trimethylene carbonate (TMC); and (ii)...
8859007 Oxygenated demineralized bone matrix for bone growth  
An improved composition for inducing bone growth is provided that is a mixture of DBM and a perfluorocarbon oxygen carrier. Injection/implantation of a composition of DBM and a perfluorocarbon...
8852623 Implantable polymeric device for sustained release of dopamine agonist  
The present invention provides compositions, methods, and kits for treatment of Parkinson's disease and other conditions for which treatment with a dopamine agonist is therapeutically beneficial....
8852620 Medical devices comprising polymeric drug delivery systems with drug solubility gradients  
Disclosed are drug delivery systems comprising drugs admixed with polymers having drug solubility gradients and methods of making the polymers. Also disclosed are medical devices having coatings...
8852622 Coated implant composed of a biocorrodible magnesium alloy  
One embodiment of the invention relates to a coated implant having a base body composed of a biocorrodible magnesium alloy. The coating of the implant comprises: (i) a base layer, which is applied...
8852624 Biomedical implants comprising surface-modified ceramic particles and biodegradable stereo complex polymers, its use for suppressing inflammation and improvement of mechanical property, and preparation method thereof  
A biomedical implant according to this invention comprises ceramic complex, which includes a surface-modified basic ceramic particles, which are basic ceramic particles modified their surface with...
8852936 Autologous lymph node transfer in combination with VEGF-C or VEGF-D growth factor therapy to treat lymphedema and to improve reconstructive surgery  
Materials and methods are provided to improve survival of lymph nodes and integration of lymph nodes into a lymphatic network, following lymph node transplantation. The treatment or prevention of...
8852580 Method and device for synovial cell-charged collagen membrane or gel  
An implant for repair of a cartilaginous defect in a subject includes a collagen matrix charged with synovial cells. A method preparing an implant for repair of a cartilaginous defect in a subject...
8852621 Multilayer fibrous polymer scaffolds, methods of production and methods of use  
Fibrous polymer scaffolds and methods of manufacture are provided. The scaffolds can be formed of multiple layers and the extent and direction of alignment of each layer can be controlled....
8852558 In situ formation of an artificial blockage to control bleeding by polymer expansion with hydrogen peroxide and platinum catalyst  
A composition for in situ formation and/or expansion of a polymer-based hemostatic agent to control bleeding includes a suitable amount of a polymer or polymer-forming component, hydrogen peroxide...
8846069 Coatings for implantable devices comprising polymers of lactic acid and methods for fabricating the same  
Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising polymers of lactic acid.
8846845 Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices  
Absorbable polyurethanes, polyamides and polyester urethanes prepared from at least one compound selected from: or the corresponding diamines or diisocyanates thereof, wherein each X independently...
8846070 Biologically degradable compositions for medical applications  
A medical article is disclosed, comprising a biologically degradable AB block copolymer and a biologically degradable polymer that is capable, at equilibrium and at room temperature, of absorbing...
8846059 Extracellular matrix adjuvant and methods for prevention and/or inhibition of ovarian tumors and ovarian cancer  
Compositions suitable for use as ovarian cancer and/or tumor adjuvants in the preparation of ovarian cancer vaccines, particularly those vaccines useful in the treatment of human ovarian cancer,...
8840933 Method of treating neuronal injury by administering magnesium chloride and PEG  
The invention provides methods and kits for treatment of pain or inflammation. In one embodiment, the kit comprises a biomembrane sealing agent, such as PEG, and a bioactive agent, such as a...
8840913 Malleable multi-component implants and materials therefor  
Described are implantable, malleable medical materials comprising mineral particles, insoluble collagen fibers, and a gel-forming polysaccharide component and/or another added gel-former. The...
8840917 Implantable graft to close a fistula  
An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the...
8840914 Method of manufacturing antimicrobial implants of polyetheretherketone  
Methods of fabricating implantable medical devices, preferably with PEEK, having antimicrobial properties, are disclosed. The antimicrobial effect is produced by incorporating ceramic particles...
8840916 Sustained release polymer  
A polymer and a method for its preparation are provided. The polymer comprises poly(lactide), poly(lactide/glycolide) or poly(lactic acid/glycolic acid) segments bonded by ester linkages to both...
8834772 Antimicrobial methacrylate cements  
Bone cement compositions and methods of making two-part bone cements. The methods comprise transferring premixed powder and a liquid component into a receptacle, and mixing the powder component and...
8834979 Bag for forming an implantable artificial organ  
A pouch for forming an implantable artificial organ, including a closed shell provided in a semi-pervious membrane. The pouch further includes a sheet contained within the shell, the sheet...
8834845 Bioactive bone cement and method for its production  
A bioactive PMMA (polymethylmethacrylate) bone cement contains a powder component and a reactive monomer liquid, wherein the powder component and the reactive monomer liquid when mixed with one...
8835174 Hemostatic device  
A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce hemostasis at an anatomical site.
8834913 Medical implants and methods of making medical implants  
A medical implant device having a substrate with an oxidized surface and a silane derivative coating covalently bonded to the oxidized surface. A bioactive agent is covalently bonded to the silane...
8834912 Medical devices having multiple charged layers  
According to an aspect of the present invention, medical devices are provided, which are adapted for implantation or insertion into a subject and which include at least one multilayer region that...
8828416 Local vascular delivery of topotecan in combination with rapamycin to prevent restenosis following vascular injury  
Medical devices, in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the...
8828417 Bioactive coating for an implantable device or bioprosthesis  
For an implantable device intended for use in the human body an in-vivo colonization with autologous cells is often desired. The devices, especially prosthetic devices like implant tissues, grafts,...
8829072 Biomaterial containing degradation stabilized polymer  
The invention provides a polymer based material comprising a water binding agent present in an amount sufficient to chemically and/or physically absorb and/or adsorb water to prevent degradation of...
8828419 Bioabsorbable device having encapsulated additives for accelerating degradation  
A medical device has a structure made of one biodegradable and/or bioabsorbable material. A degradation additive is encapsulated by another biodegradable and/or bioabsorbable material forming a...
8828358 In situ formation of an artificial blockage to control bleeding by polymer expansion with hydrogen peroxide  
A composition for in situ formation of an artificial blockage to control bleeding includes a suitable amount of a polymer-forming component, a suitable amount of a crosslinking agent, hydrogen...
8828069 Coating construct containing poly(vinyl alcohol)  
A method of forming a surface layer that includes a hydroxyl polymer on a substrate coating on a medical device is provided.
8821906 Biocompatible polymer  
The present disclosure relates to a biocompatible polymer composition for an article comprising a surface intended to contact blood, tissue, skin, epithelial layers, wounds, cells in culture...
8821533 Device for minimally invasive plastic surgery lift procedure  
Described are medical devices configured for use in cosmetic surgery. The medical devices include an elongate body member having a proximal end, a distal end, and a plurality of gaps defined...
8821912 Method of manufacturing antimicrobial implants of polyetheretherketone  
Methods of fabricating implantable medical devices, preferably with PEEK, having antimicrobial properties, are disclosed. The antimicrobial effect is produced by incorporating ceramic particles...
8821913 Controlled releases system containing temozolomide  
The present invention relates to a controlled release system, in particular to a controlled release system containing temozolomide.