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8846069 Coatings for implantable devices comprising polymers of lactic acid and methods for fabricating the same  
Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising polymers of lactic acid.
8846845 Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices  
Absorbable polyurethanes, polyamides and polyester urethanes prepared from at least one compound selected from: or the corresponding diamines or diisocyanates thereof, wherein each X independently...
8846070 Biologically degradable compositions for medical applications  
A medical article is disclosed, comprising a biologically degradable AB block copolymer and a biologically degradable polymer that is capable, at equilibrium and at room temperature, of absorbing...
8846059 Extracellular matrix adjuvant and methods for prevention and/or inhibition of ovarian tumors and ovarian cancer  
Compositions suitable for use as ovarian cancer and/or tumor adjuvants in the preparation of ovarian cancer vaccines, particularly those vaccines useful in the treatment of human ovarian cancer,...
8840933 Method of treating neuronal injury by administering magnesium chloride and PEG  
The invention provides methods and kits for treatment of pain or inflammation. In one embodiment, the kit comprises a biomembrane sealing agent, such as PEG, and a bioactive agent, such as a...
8840913 Malleable multi-component implants and materials therefor  
Described are implantable, malleable medical materials comprising mineral particles, insoluble collagen fibers, and a gel-forming polysaccharide component and/or another added gel-former. The...
8840917 Implantable graft to close a fistula  
An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the...
8840914 Method of manufacturing antimicrobial implants of polyetheretherketone  
Methods of fabricating implantable medical devices, preferably with PEEK, having antimicrobial properties, are disclosed. The antimicrobial effect is produced by incorporating ceramic particles...
8840916 Sustained release polymer  
A polymer and a method for its preparation are provided. The polymer comprises poly(lactide), poly(lactide/glycolide) or poly(lactic acid/glycolic acid) segments bonded by ester linkages to both...
8834772 Antimicrobial methacrylate cements  
Bone cement compositions and methods of making two-part bone cements. The methods comprise transferring premixed powder and a liquid component into a receptacle, and mixing the powder component and...
8834979 Bag for forming an implantable artificial organ  
A pouch for forming an implantable artificial organ, including a closed shell provided in a semi-pervious membrane. The pouch further includes a sheet contained within the shell, the sheet...
8834845 Bioactive bone cement and method for its production  
A bioactive PMMA (polymethylmethacrylate) bone cement contains a powder component and a reactive monomer liquid, wherein the powder component and the reactive monomer liquid when mixed with one...
8835174 Hemostatic device  
A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce hemostasis at an anatomical site.
8834913 Medical implants and methods of making medical implants  
A medical implant device having a substrate with an oxidized surface and a silane derivative coating covalently bonded to the oxidized surface. A bioactive agent is covalently bonded to the silane...
8834912 Medical devices having multiple charged layers  
According to an aspect of the present invention, medical devices are provided, which are adapted for implantation or insertion into a subject and which include at least one multilayer region that...
8828416 Local vascular delivery of topotecan in combination with rapamycin to prevent restenosis following vascular injury  
Medical devices, in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the...
8828417 Bioactive coating for an implantable device or bioprosthesis  
For an implantable device intended for use in the human body an in-vivo colonization with autologous cells is often desired. The devices, especially prosthetic devices like implant tissues, grafts,...
8829072 Biomaterial containing degradation stabilized polymer  
The invention provides a polymer based material comprising a water binding agent present in an amount sufficient to chemically and/or physically absorb and/or adsorb water to prevent degradation of...
8828419 Bioabsorbable device having encapsulated additives for accelerating degradation  
A medical device has a structure made of one biodegradable and/or bioabsorbable material. A degradation additive is encapsulated by another biodegradable and/or bioabsorbable material forming a...
8828358 In situ formation of an artificial blockage to control bleeding by polymer expansion with hydrogen peroxide  
A composition for in situ formation of an artificial blockage to control bleeding includes a suitable amount of a polymer-forming component, a suitable amount of a crosslinking agent, hydrogen...
8828069 Coating construct containing poly(vinyl alcohol)  
A method of forming a surface layer that includes a hydroxyl polymer on a substrate coating on a medical device is provided.
8821906 Biocompatible polymer  
The present disclosure relates to a biocompatible polymer composition for an article comprising a surface intended to contact blood, tissue, skin, epithelial layers, wounds, cells in culture...
8821533 Device for minimally invasive plastic surgery lift procedure  
Described are medical devices configured for use in cosmetic surgery. The medical devices include an elongate body member having a proximal end, a distal end, and a plurality of gaps defined...
8821912 Method of manufacturing antimicrobial implants of polyetheretherketone  
Methods of fabricating implantable medical devices, preferably with PEEK, having antimicrobial properties, are disclosed. The antimicrobial effect is produced by incorporating ceramic particles...
8821913 Controlled releases system containing temozolomide  
The present invention relates to a controlled release system, in particular to a controlled release system containing temozolomide.
8821583 Interpenetrating polymer network hydrogel  
A strain-hardened interpenetrating polymer network (IPN) hydrogel is provided. The interpenetrating polymer network hydrogel is based on two different networks. The first network is a non-silicone...
8821911 Coating and coating method  
The present invention discloses a coating for a medical implant, wherein at least a part of said coating contains an osseointegration agent and the same and/or a different part of the coating...
8815275 Coatings for medical devices comprising a therapeutic agent and a metallic material  
The invention relates generally to an implantable medical device for delivering a therapeutic agent to the body tissue of a patient, and a method for making such a medical device. In particular,...
8815276 Three-dimensional nanostructured hybrid scaffold and manufacture thereof  
A method of making a three-dimensional biocompatible scaffold capable of supporting cell activities such as growth and differentiation, the method includes providing a supporting grid that forms an...
8815973 Cement products and methods of making and using the same  
Disclosed are cement products, methods of forming cement using the cement product, and methods of using the cement product in orthopedic and dental applications. Generally, the disclosed cement...
8813753 Implantable obstructive sleep apnea sensor  
Systems and methods for detecting an obstructive sleep apnea event are disclosed herein. The systems and methods may use an electrical output generating ionic polymer metal composite sensor...
8815274 Poly(ester amides) for the control of agent-release from polymeric compositions  
The present invention generally encompasses a medical article, such as a medical device or coating comprising an agent or combination of agents, wherein the agent is distributed throughout a...
8815277 In situ forming hydrogel and biomedical use thereof  
Disclosed are in situ-forming injectable hydrogel and medical uses thereof. In the in situ-forming injectable hydrogel two or more homogeneous or heterogeneous polymers are bonded to each other by...
8808723 Polymers containing poly(ester amides) and agents for use with medical articles and methods of fabricating the same  
Polymers containing poly(ester amides) and agents for use with medical articles and methods of fabricating the same are disclosed. The medical article generally comprises an implantable substrate...
8808727 Posterior segment drug delivery  
A therapeutic device to release a therapeutic agent comprises a porous structure coupled to a container comprising a reservoir. The reservoir comprises a volume sized to release therapeutic amounts...
8808725 Solid forms for tissue repair  
This invention provides coral-based scaffolds for cartilage repair, and instruments for insertion and utilization of same within a site of cartilage repair.
8808357 Radiopaque iodinated and iodide-containing crystalline absorbable aliphatic polymeric materials and applications thereof  
Radiopaque, iodinated, absorbable polyesters, polyester urethanes, and polyether-ester-urethanes with and without inorganic iodide micro-/nanoparticles dispersed or solubilized therein, and...
8808724 Antimicrobial coatings with preferred microstructure for medical devices  
A medical device having an antimicrobial coating. The device has a first coating layer having an antimicrobial agent over at least part of the outer surfaces of the device. The first coating has an...
8802184 Medical devices containing biobeneficial particles  
A method of modifying a medical device such as a stent with nano-constructs is disclosed. The method comprises applying a first fluid to the stent; immersing the stent being wet from the first...
8802122 Multi-phased, biodegradable and osteointegrative composite scaffold for biological fixation of musculoskeletal soft tissue of bone  
Methods and apparatuses are provided for musculoskeletal tissue engineering. For example, a scaffold apparatus is provided which comprises microspheres of selected sizes and/or composition. The...
8801694 Intravesical drug delivery device  
Implant devices for intravesical administration and local drug delivery. The device has a body which includes a hollow tube formed of a biocompatible material; at least one reservoir in the tube...
8802123 Endosseous implant  
Endosseous implant to be applied to a human or animal bone, wherein the surface of the implant is made from titanium or a titanium alloy, said implant having a smooth or rough surface texture,...
8802113 Extracellular matrix cancer vaccine adjuvant  
Compositions suitable for use as adjuvants in the preparation of vaccines, particularly those vaccines useful in the treatment of cancer, are provided. Methods for inhibiting tumor growth in an...
8795705 Dermatologic compositions comprising pyrrolidone-5-carboxylic acid and at least one entity chosen from citrulline, arginine and asparagine, and uses thereof in the treatment of atopic dermatitis  
Combination comprising pyrrolidone-5-carboxylic acid and at least one compound from citrulline, arginine and asparagine, and use thereof in the treatment of atopic dermatitis The present invention...
8795712 Posterior segment drug delivery  
A therapeutic device to release a therapeutic agent comprises a porous structure coupled to a container comprising a reservoir. The reservoir comprises a volume sized to release therapeutic amounts...
8795706 Methods of treating ocular diseases using derivatives of lipoic acid  
Methods of treating ocular diseases using dithiol compounds, their derivatives, and pharmaceutically acceptable salts thereof are disclosed. In particular, methods using dithiol compounds that...
8795703 Stand-alone film and methods for making the same  
A stand-alone film is derived at least in part from fatty acids. The stand-alone film can have anti-adhesive, anti-inflammatory, non-inflammatory, and wound healing properties, and can additionally...
8795707 Compliant composites for application of drug-eluting coatings to tissue surfaces  
A compliant composite for delivering a bioactive agent including a scaffolding material and a polymer coating that together can be attached to compliant tissue surfaces is disclosed, along with...
8795728 Compositions for regenerating defective or absent myocardium  
Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an...
8795708 Treating defective dura with synthetic artificial dura substitute  
Disclosed are an artificial dura mater and manufacturing method thereof. The artificial dura mater includes electrospun layers prepared by electrostatic spinning, at least one of which is a...