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6485735 |
Multilayer thermoset polymer matrix and structures made therefrom
A composite thermoset polymer matrix structure having a plurality of homogeneously bonded thermoset polymer layers and a method of forming the same is disclosed. Each of the layers is formed from...
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6482426 |
Compositions for the treatment of male erectile dysfunction
Improved drug compositions and methods useful in the treatment of male erectile dysfunction. An optimized mixture of the drugs phentolamine mesylate, papaverine hydrochloride, and alprostadil in a...
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6479063 |
Therapeutic uses of hormonal manipulation using combinations of various agents to treat atherosclerosis
A method of decreasing atherosclerosis and its complications involving administering to a human or animal various combinations of medications with Finasteride, Bicalutamide, Flutamide and Nilutamide.
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6479072 |
Microfabricated membranes and matrices
The invention relates to microfabricated membranes and matrices that have a highly controlled and complex three-dimensional topography. The new micro fabricated membranes and matrices can be...
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6479232 |
Human xenografts for microbicide testing and anatomical modeling
A method for screening candidate antimicrobial compounds is described that utilizes a human vaginal xenograft engrafted in a non-human host. The method may be performed by using pathogen inoculated...
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6479045 |
Vaginal pH buffering for preventing miscarriage and premature labor, by treating or preventing bacterial vaginosis
The present invention concerns compositions and methods for preventing miscarriage and premature labor, and for treating and preventing Bacterial Vaginosis using a pH-buffering polymer. The present...
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6476071 |
Correcting polymorphic metabolic dysfunction with (−)-hydroxycitric acid
A method whereby in an individual showing evidence of dysregulation of elements of the Polymorphic Metabolic Dysfunction (PMD), which is defined as the dysregulation of the metabolism of insulin,...
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6475506 |
Infusion preparation
Disclosed is an infusion preparation for nutrient supply use. It comprises a sugar, amino acids, electrolytes and a fat emulsion. It has an excellent shelf life without causing precipitation,...
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6476069 |
Compositions for creating embolic agents and uses thereof
A composition useful as an embolic agent that selectively creates an embolic blockage in the lumen of a blood vessel, duct, fistula or other like body passageways by combining a monomer component...
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6475466 |
Methods for treating endoleaks during endovascular repair of abdominal aortic aneurysms
Disclosed are methods for treating endoleaks arising from endovascular repair of abdominal aortic aneurysms. The disclosed methods involve the in situ sealing of endoleaks after placement of an...
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6476079 |
Devices for the delivery of drugs having antiprogestinic properties
A device for the controlled release over a prolonged period of time of a drug having antiprogestinic properties, the device including a core containing the drug, optionally a membrane encasing the...
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6471970 |
Use of pharmaceutical compositions capable of being gelled in periodontology
A method is described for preparing a fluid pharmaceutical composition which allows the controlled release of at least one active substance. The method involves mixing a therapeutically effective...
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6471993 |
Three-dimensional polymer matrices
Matrices that include a macrostructure having a semi-solid network and voids, and a microstructure having voids, in which the microstructure is located within the semi-solid network are disclosed....
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6471978 |
Localized use of nitric oxide-adducts to prevent internal tissue damage
A method for preventing adverse effects associated with the use of a medical device in a patient by introducing into the patient a device of which at least a portion includes a prophylactic or...
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6471979 |
Apparatus and method for delivering compounds to a living organism
A method of treating or preventing vascular disease in a living organism. The method includes delivering an effective amount of a composition including a sex hormone, anti-hormone, sex-hormone...
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6471987 |
Drug releasing elastic band and method
A ligating band according to the present invention comprises an elastomeric layer and an inner drug releasing layer. The inner drug releasing layer includes a therapeutic agent, for example a...
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6468521 |
Stabilized compositions having antibacterial activity
A stabilised composition having antibacterial, antiviral and/or antifungal activity characterised in that it comprises a silver compound and that the compound is in the form of a complex with a...
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6465000 |
Method for penile augmentation with autogenous dermal cell culture
The present invention relates to a penile augmentation method comprising culturing autodermal cells in a laboratory and inserting this into penis by using scaffold. This method has advantage of...
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6465001 |
Treating medical conditions by polymerizing macromers to form polymeric materials
Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions...
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6464998 |
Composition for the in vivo production of therapeutic products
The present invention provides cell compositions for in vivo implantation, and designed for the sustained and controlled delivery of therapeutic substances.
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6464999 |
Bioadhesive medical devices
Disclosed herein are bioadhesive medical devices formed in whole or in part of a cohesive bioadhesive copolymer of a carboxyl functional monomer and a hydrophobic functional monomer.
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6464987 |
Pharmaceutical compositions capable of being gelled
A fluid pharmaceutical composition is described which allows the controlled release of at least one active substance. The composition comprises a therapeutically effective amount of at least one...
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6461629 |
Method of nerve regeneration using biopolymer rods with oriented fibrils
Tissue-equivalent and biopolymer tubes and rods include fibrils which are oriented (aligned) by a magnetic field. These oriented fibrils provide enhanced mechanical and cell guidance properties to...
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6461632 |
Hardenable ceramic hydraulic cement
A method for delivering a therapeutically effective drug via a hardenable ceramic hydraulic cement composition including a first component of at least one sodium or calcium salts of inorganic and...
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6461633 |
Reducing sugar-containing fat emulsion and a method for its sterilization
The invention provides a reducing sugar-containing fat emulsion comprising an oil-in-water fat emulsion available upon emulsification of a fat with an emulsifier wherein a reducing sugar and at...
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6458375 |
Malleable paste with allograft bone reinforcement for filling bone defects
The invention is directed toward a sterile malleable bone composition for application to a bone defect site to promote new bone growth at the site comprising a mixture of demineralized osteogenic...
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6458380 |
Dressing and preparation delivery system
A dressing and method of treating wounds is provided. The dressing can comprise water-soluble or swellable polymers which are capable of forming a viscous aqueous or non-aqueous solution and form a...
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6455034 |
Method for inhibiting the development of body odors
Methods, compositions and products are described which inhibit the development of odor in excreted body fluids by odor-causing cations.
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6455060 |
S(&plus ) desmethylselegiline and its use to treat immune system dysfunction
The present invention provides novel compositions and methods for using the S(+) enantiomer of desmethylselegiline (N-methyl-N-(prop-2-ynyl)-2-aminophenylpropane), for the treatment of...
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6455495 |
Methods and compositions for delivery of therapeutic agents to bone tissue employing conjugates of negatively charged peptide oligomers with therapeutic agents
The invention provides conjugates of negatively charged peptide oligomers with therapeutic agents, moieties capable of recruiting endogenous bone-affecting agents, or imaging agents, useful for...
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6451337 |
Chitosan-based nitric oxide donor compositions
A chitosan-based polymeric nitric oxide donor composition comprising a modified chitosan polymer and a nitric oxide [N 2 O 2 ] dimer, wherein the nitric oxide [N 2 O 2 ] dimer is bonded directly to...
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6451779 |
Composition and method for contraception and treatment of tumors of the mammary glands
A composition with three hormone components is administered to a mammal to cause the suppression or cessation of the menstruation cycle. Alternatively, it can be administered for treatment of...
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6447542 |
Implantable members for receiving therapeutically useful compositions
An implantable prosthesis includes a porous polymeric member having pores present in its wall structure wherein these pores contain a variety of therapeutically useful compositions including,...
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6444222 |
Reinforced matrices
A reinforced matrix membrane containing one or more scaffold-forming proteins suitable for cell growth and for use in chondrocyte cell transplantation, and method of making same. The scaffold is...
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6444224 |
Intra-vaginal device for pigs
Disclosed herein is a porcine intra-vaginal device of a shape and size adapted to be positionable in the vaginal tract across the hymenal ring of a target animal (e.g., a gilt) to extend to both...
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6440452 |
Therapeutic enclosures
Devices and methods for enhancing the healing of wounds, especially chronic wounds (e.g., diabetic wounds), involving the use of keratinocytes are described. Keratinocytes are grown on a...
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6440444 |
Load bearing osteoimplant and method of repairing bone using the same
A load-bearing osteoimplant, method of making the osteoimplant and method for repairing bone using the osteoimplant are provided. The osteoimplant comprises a shaped, compressed composition of bone...
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6440427 |
Tissue treatment composition comprising fibrin or fibrinogen and biodegradable and biocompatible polymer
A tissue treatment composition, especially an adhesive composition comprises (i) fibrin or fibrinogen and (ii) a biodegradable and biocompatible polymer capable of forming a viscous aqueous...
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6436937 |
Use of desoxypeganine in the treatment of Alzheimer's dementia
The invention relates to a device and method for the treatment of Alzheimer's dementia with desoxypeganine and/or a pharmaceutically acceptable acid addition salt of desoxypeganine.
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6436440 |
Use of N-vinyllactam-or-N-vinylamine-containing copolymers as matrix for producing solid pharmaceutical and cosmetic presentations
The use of copolymers comprising a) 50 to 99% by weight of at least one N-vinyllactam or N-vinylamine selected from the group consisting of N-vinylpyrrolidone, N-vinylpiperidone,...
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6432436 |
Partially demineralized cortical bone constructs
The invention is directed toward a sterile bone structure for application to a bone defect site to promote new bone growth at the site comprising a partially demineralized cortical bone structure,...
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6432438 |
Biodegradable vehicle and filler
A biodegradable vehicle and filler (referred to in this invention as biodegradable vehicle), which can be mixed with one or more biologically active substances (BAS), or can be used as a...
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6432435 |
Keratin-based tissue engineering scaffold
Methods for producing thin keratin films, sheets, and bulk materials, and products formed using these methods. One method includes providing hair, reducing the hair such that the disulfide linkages...
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6432434 |
Treatment of and/or prophylaxis against brain and spinal cord injury
The administration of α-lipoic acid (αLA) and dihydrolipoic acid (DHL) both as a preventive measure before exposure to conditions which may cause damage, such as rapid changes in atmospheric...
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6428804 |
Intra-articular preparation for the treatment of arthropathy
This invention relates to an intra-articular preparation for the treatment of arthropathy, which comprises microcapsules of (a) a high-molecular substance, which has biodegradability and...
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6426367 |
Methods for selectively occluding blood supplies to neoplasias
Disclosed are methods of selectively reducing the blood supply to a neoplastic region, such as a tumor region, thereby selectively causing necrosis of the neoplastic tissue without substantial...
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6426084 |
Treatment of sexual dysfunction in certain patient groups
Methods for treating specific patient groups for sexual dysfunction are provided. The methods of the present invention comprise the utilization of pharmaceutical compositions in patients who are...
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6423332 |
Method and composition for deforming soft tissues
The present invention provides a composition and method for augmenting soft tissue, which composition includes a continuous phase that is a solid at temperatures less than about 10° C. or greater...
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6423321 |
Cytokine antagonists for the treatment of sensorineural hearing loss
Specific Cytokine Antagonists, including TNF antagonists and/or Interleukin-1 antagonists, are used as novel therapeutic agents for the treatment of hearing loss, including presbycusis and other...
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6419934 |
TNF modulators for treating neurological disorders associated with viral infection
A method for inhibiting the action of TNF for treating neurological conditions in a human by administering a TNF antagonist for reducing the inflammation of neuronal tissue of said human, or for...
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