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9101543 Combinations and modes of administration of therapeutic agents and combination therapy  
The present invention provides combination therapy methods of treating proliferative diseases (such as cancer) comprising a first therapy comprising administering to an individual an effective...
9040061 Topical formulation for administering a compound  
Embodiments of topical formulations for administering compound I or a pharmaceutically acceptable salt or solvate thereof are disclosed. Embodiments of methods for using the topical formulations...
9040060 Hydrolytically degradable alkylene oxide based polymers  
The present invention provides a water soluble, non-peptidic polymer comprising two or more alkylene oxide-based oligomers linked together by hydrolytically degradable linkages such as carbonates....
9039979 Apparatus and method of reacting polymers passing through metal ion chelated resin matrix to produce injectable medical devices  
The present disclosure relates to an apparatus and process for forming medical devices from an injectable composition. The apparatus includes a supply assembly configured to maintain and selective...
9040063 Orally administrable gallium compositions and methods of use  
Provided are pharmaceutical gallium compositions that are particularly useful for oral administration. The pharmaceutical compositions include solid, liquid, and paste formulations, which have...
9040062 Preparation for treatment of spinal cord injury  
The present invention is a solid sustained-release formulation comprising an agent for inhibiting semaphorin 3A as an active ingredient, which comprises an agent for inhibiting semaphorin 3A and...
9034941 Hydrophilic gels from polyurethane-based photoinitiators  
The present invention relates to the use of polymeric photoinitiators based on polyalkyletherurethane backbones in the production of hydrophilic gels, in particular hydrogels. The invention...
9034644 Compositions for repair of defects in osseous tissues, and methods of making the same  
Tissue repair compositions, particularly bone repair compositions, containing demineralized bone fragments and homogenized connective tissues, and methods for making the same. The compositions can...
9034830 Methods and compositions for sustained delivery of drugs  
The present disclosure relates to methods and compositions for the topical sustained delivery of therapeutic agents. Topical application of compositions containing a muscle fasciculating agent...
9034346 Implantable or insertable medical device resistant to microbial growth and biofilm formation  
Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm...
9034359 Composition comprising biodegradable hydrating ceramics for controlled drug delivery  
The present invention relates to a drug carrier composition comprising i) one or more biodegradable hydrating ceramics ii) one or more expandable agents, and iii) sorbed aqueous medium which in...
9034348 Injectable chitosan mixtures forming hydrogels  
A chitosan composition which forms a hydrogel at near physiological pH and 37° C., comprising at least one type of chitosan having a degree of acetylation in the range of from about 30% to about...
9033910 Transdermal drug delivery bracelet  
The invention relates to a bracelet that is suitable for the transdermal delivery of various substances. The invention relates to, for example, a refillable, hollow bracelet that contains the...
9034349 Compositions and methods for treating a damaged cardiovascular element  
In the present invention, the applicants describe methods and compositions of treating damaged cardiovascular elements and cardiovascular conditions including hypotension, atherosclerotic lesions,...
9034347 Drug delivery system and method for the treatment of neuro-degenerative disease  
Embodiments of the present invention are directed to the oral administration of Bryostatins for the treatment of neuro-degenerative disease.
9028846 Beds and bed accessories having an antimicrobial treatment  
A hospital bed is provided that may include a support structure having a plurality of surfaces coated with an antimicrobial treatment, which may include a silane quaternary ammonium salt and...
9028851 Hemostatic materials and devices with galvanic particulates  
The present invention is directed to a hemostatic material comprising a scaffold and a galvanic particulate. The galvanic particulate comprises particles made of at least two dissimilar metals....
9028871 Resorbable ceramics with controlled strength loss rates  
Particular aspects provide bioresorbable and biocompatible compositions for bioengineering, restoring or regenerating tissue or bone, comprising a three-dimensional porous or non-porous scaffold...
9028847 Sodium alginate crosslinked slow-release moxifloxacin microsphere, the preparation method and the use thereof, and target vascular occlusive agent of the microsphere  
A sodium alginate crosslinked slow-released moxifloxacin microsphere, the preparation method of the microsphere, a vascular target embolus containing the microsphere and the use of the microsphere...
9029355 Solid ganaxolone compositions and methods for the making and use thereof  
In certain embodiments, the invention is directed to composition comprising stable particles comprising ganaxolone, wherein the volume weighted median diameter (D50) of the particles is from about...
9023369 Freeze-dried composition of active substances  
The invention relates to freeze-dried molded articles, containing ≧50% by wt. of one or more active substances, and ≦15% by wt. of one or more scaffold-forming agents, with proteins being...
9023370 Conjugates comprising nanoparticles coated with platinum containing compounds  
The present invention relates to conjugates of formula (I) having colloidal stability in a medium, wherein NP is a gold, silver or platinum nanoparticle; L is a linker selected from the group...
9023391 Stable benzimidazole formulation  
A stable composition with a benzimidazole derivative, such as Omeprazole, which does not contain a separating layer between the active compound and an enteric coating layer. Instead, the enteric...
9023371 Drug releasing coatings for medical devices  
Medical device are provided for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic...
9023388 Formulation of silibinin with high efficacy and prolonged action and the preparation method thereof  
A high-efficacy, long-acting formulation of silibinin, comprising silibinin solid dispersion, silibinin-loaded silica nanoparticles, slow-release matrix material and release enhancer, wherein the...
9023368 Colonic drug delivery formulation  
A delayed release coating comprising a mixture of a first material selected from starch; amylose; amylopectin; chitosan; chondroitin sulfate; cyclodextrin; dextran; pullulan; carrageenan;...
9017702 Stable aqueous formulations comprising poorly water soluble active ingredients  
A formulation includes one or more active ingredients of poor water solubility for medical or non-medical use in the rearing of animals. The formulation is suitable for administration to the...
9016221 Surface topographies for non-toxic bioadhesion control  
Disclosed herein is an article that includes a first plurality of spaced features. The spaced features are arranged in a plurality of groupings; the groupings of features include repeat units; the...
9017728 Stable corticosteroid nanoparticulate formulations and methods for the making and use thereof  
Disclosed are stable corticosteroid nanoparticulate formulations, methods of making and therapeutic uses thereof.
9017703 Method of using fibrous tissue sealant  
Disclosed herein is a fibrous tissue sealant in the form of an anhydrous fibrous sheet comprising a first component which is a fibrous polymer containing electrophilic or nucleophilic groups and a...
9017701 Organogel compositions comprising alkylated benzimidazolones  
Disclosed is a composition comprising an organogel which comprises: (a) an alkylated benzimidazolone compound; and (b) an organic liquid.
9011933 Therapeutic methods and pharmaceutical compositions for treating warts with tellurium compounds  
A novel method for treating skin and mucosal membrane ailments caused by human papilloma viruses, which utilizes tellurium-containing compounds, is disclosed. Also disclosed are pharmaceutical...
9011881 Pharmaceutical composition for treating urinary system disorders  
A pharmaceutical composition for treating urinary system disorders includes a carbon material carried by a water-containing carrier and having a carbon content over 60 percentage by weight (wt %),...
9011309 Devices for thermally induced transformations controlled by irradiation of functionalized fullerenes  
An electromagnetic radiation activated device comprises a property changing material and at least one functionalized fullerene that upon irradiation of the functionalized fullerenes with...
9011882 Dimethylarginine dimethylaminohydrolase inhibitors and methods of use thereof  
The present disclosure provides DDAH modulators. Thus, the present disclosure provides a method of treating a patient suffering from a disorder characterized by excessive NO production and/or...
9012399 Controlled release of growth factors and signaling molecules for promoting angiogenesis  
The present invention comprises compositions, methods, and devices for delivering angiogenic factors and signaling molecules to a target tissue, and controlling the release of these factors and...
9011883 Reducing post-operative adhesion formation with intraperitoneal glutamine  
Intraperitoneal administration of glutamine to reduce adhesions in the peritoneum of a patient.
9011884 Embolic devices  
Described herein are apparatus, compositions, systems and methods for occluding vascular structures and vascular malformations with radiopaque hydrogel filaments. The filaments can contain no...
9011885 Method of treating acne  
The use, as a dermatological or cosmetic medicament, of compounds capable of transiently interacting with the AhR receptor (aryl hydrocarbon receptor) as agents for modulating skin functions such...
9006294 Oral pharmaceutical formulation of pelubiprofen with improved dissolution rate and stability  
Disclosed is an oral pharmaceutical formulation of pelubiprofen which is improved in dissolution rate and stability. As a result of an improvement in the dissolution rate of pelubiprofen, the oral...
9005637 Multiple unit dosage form having a therapeutic agent in combination with a nutritional supplement  
Compositions and methods for combination therapy are provided. The compositions comprise a multiple unit dosage form having both a therapeutic agent and a nutritional supplement. The combination...
9005664 Denatured lactoglobulin and polyphenol coassemblies  
The present invention is directed to co-assembled nanoparticle composition comprising denatured β-lactoglobulin and at least one nutraceutical compound, specifically polyphenols, such as EGCG,...
9005646 Compositions for repair of defects in tissues, and methods of making the same  
Tissue repair compositions, particularly bone repair compositions, containing (a) bone fragments and (b) homogenized connective tissue, and methods for making the same are provided. Some of the...
9005608 Stabilized solubility-enhanced formulations for oral delivery  
Methods and compositions are described whereby poorly water-soluble beneficial agents such as vitamins and co-factors are formulated into self-emulsifying formulas (SEF) and optionally sorbing the...
9005634 Shelf stable pharmaceutical depot  
A pharmaceutical depot includes a biodegradable polymer having a glass transition temperature of 20 degrees centigrade or less and at least 25% wt solid particles suspended in the biodegradable...
9005635 Articles and processes for making a porous disintegratable solid substrate for personal health care applications  
A personal health care article. More particularly, a personal health care article comprising at least one porous disintegratable solid substrate comprising: from about 1% to about 70%, by weight...
9005636 Pharmaceutical composition comprising metformin and rosuvastatin  
This invention relates to oral pharmaceutical compositions of metformin and rosuvastatin. In detail, a pharmaceutical composition comprising metformin, rosuvastatin, sustained release carriers...
9005161 Drug releasing coatings for medical devices  
The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a...
8997672 Surface topographies for non-toxic bioadhesion control  
An article has a surface topography for resisting bioadhesion of organisms and includes a base article having a surface. A composition of the surface includes a polymer. The surface has a...
8999355 Non-rinse off cosmetic composition and a cosmetic product comprising said composition  
The present invention relates to a non-rinse-off cosmetic composition that provides to the skin, especially the lip skin, a hydrating and restoring action. More specifically, the invention relates...