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8361273 Polyurethane elastomers  
This disclosure relates to a linear polymer obtained by reacting a polyethylene glycol, a polypropylene glycol; a diol; and a diisocyanate, as well as a controlled release composition containing...
8361497 Multi-phase, multi-compartment, capsular delivery apparatus and methods for using the same  
A multi-compartment capsule, comprising, a first receiving chamber comprising at least one ingredient having a first physical state, wherein said ingredient is selected from the group consisting of...
8362085 Method for administering an NMDA receptor antagonist to a subject  
The invention provides methods for administering memantine to a subject. Memantine in an extended release form containing 22.5 to 30 mg memantine or a pharmaceutically acceptable salt is...
8357379 High concentration baclofen preparations  
Stable aqueous solutions comprising concentrations of baclofen in the range of greater than 2.0 mg/mL up to about 10 mg/mL are disclosed. These solutions can be used as pharmaceuticals for...
8357377 Cyclodextrin-based materials, compositions and uses related thereto  
This application discloses cyclodextrin-modified materials for carrying drugs and other active agents, such as nucleic acids. Compositions are also disclosed of cyclodextrin-modified materials that...
8357380 Coenzyme Q10-containing composition  
The coenzyme Q10-containing liquid composition is obtained by dispersing and emulsifying coenzyme Q10 in an aqueous liquid containing a water-soluble substance consisting of octenylsuccinate starch...
8357378 Fragmented polymeric compositions and methods for their use  
Cross-linked hydrogels comprise a variety of biologic and non-biologic polymers, such as proteins, polysaccharides, and synthetic polymers. Such hydrogels preferably have no free aqueous phase and...
8357399 Tamper-resistant oral opioid agonist formulations  
Disclosed is an oral dosage form comprising: (i) an opioid agonist in releasable form and (ii) a sequestered opioid antagonist which is not released when the dosage form is administered orally intact.
8354116 Bifunctional synthetic molecules  
The synthesis and use of bifunctional molecules to improve the topical and transdermal delivery efficiency of various types of therapeutic agents or agents designed to promote the transdermal...
8354466 Method for formulating agrochemical active ingredients so as to regulate their release kinetics, protect them from outside stresses, and keep their users safe  
The invention pertains to a new method for formulating any agrochemical active ingredient so as to protect the user, protect this active ingredient from outside stresses, and control its release...
8354117 Preparation for oral cavity  
Object of the present invention is to provide a preparation for oral cavity that is appropriately usable as a prophylactic agent for dental caries, a therapeutic agent for dental caries at early...
8353399 Preparation-at-use device comprising pre-formed hydrogel product  
Disclosed is a preparation-at-use device comprising: (1) a pre-formed hydrogel component packaged in a first compartment; the pre-formed hydrogel component comprising a gelling agent and a solvent;...
8349882 Pharmaceutical composition for external use  
A pharmaceutical composition for external use, including: i) luliconazole represented by the following structural formula (1) and/or a salt thereof; and ii) one or two or more selected from...
8349348 Biocompatible phase invertible proteinaceous compositions and methods for making and using the same  
Biocompatible phase invertible proteinaceous compositions and methods for making and using the same are provided. The subject phase invertible compositions are prepared by combining a proteinaceous...
8343942 Methods for treating interstitial cystitis  
Described herein are methods for treating interstitial cystitis in a subject comprising administering to the subject an effective amount of a compound which is a modified hyaluronan or a...
8343513 Prevention of molecular weight reduction of the polymer, impurity formation and gelling in polymer compositions  
Polymer and drug containing compositions and method of preparing such compositions are disclosed. The dispersed phase formulation has a polymer, a pharmaceutically or biologically active agent and...
8343518 Preservation of bioactive materials by freeze dried foam  
This invention provides methods and compositions to preserve bioactive materials in a dried foam matrix. Methods provide non-boiling foam generation and penetration of preservative agents at...
8343514 Sol-gel nanostructured titania reservoirs for use in the controlled release of drugs in the central nervous system and method of synthesis  
The invention is related to a sol-gel nanostructured titania reservoir and its synthesis which is biocompatible with brain tissue. The pore size distribution, crystallite size and the extent of the...
8343543 Lipase inhibiting composition  
Pharmaceutical compositions that contain a lipase inhibitor having a melting point ≧37° C., a sucrose fatty acid ester wherein the sucrose fatty acid ester is a mono-, di-, tri- or tetra-ester, an...
8343464 Composition and method for treating eustachian tube dysfunction  
A method of treating Eustachian tube dysfunction in a person includes placing the person's body in a position substantially lying on one of the person's left or right sides. The side on which the...
8344032 Composition for enhancing athletic performance  
A composition including a plurality of active ingredients. A first active ingredient of the active ingredients is pyruvate. For each other active ingredient, an amount of that active ingredient is...
8343515 Perfluorocarbon gel formulations  
A perfluorocarbon gel composition is disclosed with numerous uses including topical medical and cosmetic uses.
8343516 Solid drug tablets for implantable drug delivery devices  
A drug dosage form is provided in the form of a solid tablet which is greater than 50% by weight the local anesthetic agent. The local anesthetic agent may be selected from the group consisting of...
8343212 Polymer coatings on medical devices  
A medical device, for example a stent, has a surface which in use contacts body tissue, wherein said surface has on it a biocompatible coating layer comprising a polymer having covalently bound...
8343517 Multivitamin-mineral longevity regimen  
A novel dietary supplement is featured which can benefit individuals suffering from various conditions such as nutritional deficiencies, vitamin deficiencies, aging, cancer, high blood pressure,...
8338428 Methods for administering aripiprazole  
The present invention relates, in part, to the discovery that a pharmaceutical composition comprising aripiprazole and a carrier administered in a bolus injection resulted in an extended release...
8337877 Reduction of infection associated with medical device  
Anti-infective articles capable of preventing infection associated with implantation of medical devices include low levels of anti-infective agents, may cover only a fraction of the portion of the...
8338485 Compositions for the treatment of CNS-related conditions  
The invention provides compositions comprising extended release memantine in combination with immediate release donepezil to a subject. Memantine in an extended release form containing 22.5 to 30...
8338486 Methods for the treatment of CNS-related conditions  
The invention provides methods for administering extended release memantine in combination with immediate release donepezil to a subject. Memantine in an extended release form containing 22.5 to 30...
8338427 Methods for administering aripiprazole  
The present invention relates, in part, to the discovery that a pharmaceutical composition comprising aripiprazole and a carrier administered in a bolus injection resulted in an extended release...
8337868 Stinging cells expressing an exogenous polynucleotide encoding a therapeutic, diagnostic or a cosmetic agent and methods compositions and devices utilizing such stinging cells or capsules derived therefrom for delivering the therapeutic, diagnostic or cosmetic agent into a tissue  
A stinging cell comprising an exogenous polynucleotide capable of expressing a therapeutic, cosmetic or diagnostic agent in the stinging cell is provided.
8337867 Metal lactate powder and method for preparation  
The present invention relates to a method for the preparation of a new metal lactate powdery product and to the resulting product itself with new properties. The metal lactate powder of the present...
8333981 Antifungal treatment of nails  
A fungus treatment composition used to deliver active drugs trans-nail as well as a method for producing the fungus treatment composition, which may contain up to 50% additive ingredients....
8334321 Prostaglandin fat emulsion, method for producing the same, method for stabilizing the same, and emulsifying agent  
A fat emulsion comprises a prostaglandin as an active ingredient, the fat emulsion comprising a phospholipid that comprises phosphatidylcholine (PC) and phosphatidylglycerol (PG) and has a ratio of...
8329752 Composition for administering an NMDA receptor antagonist to a subject  
The invention provides compostions for administering memantine to a subject. Memantine in an extended release form containing 22.5 to 30 mg memantine or a pharmaceutically acceptable salt achieves...
8329198 Pharmaceutical compositions and related methods of delivery  
The pharmaceutical compositions described herein include a suspension which comprises an admixture in solid form of a therapeutically effective amount of a therapeutic agent and at least one salt...
8329760 Pharmaceutical composition  
A pharmaceutical compositions in the form of an emulsion and containing a continuous liquid phase, for example, an aqueous phase, liquid droplets dispersed in the continuous phase, a...
8329761 Oil-in-oil emulsions  
An stable oil-in-oil emulsion is disclosed containing a first oil phase dispersed as droplets in a continuous second oil phase, which droplets have a number median diameter of 10 nm to 1000 nm,...
8329199 Compositions that include a hydrophobic compound and a polyamino acid conjugate  
Various compositions that include a hydrophobic compound and a polyamino acid conjugate are prepared. The compositions described herein are useful for a variety of drug, biomolecule, and imaging...
8329208 Pharmacokinetics of S-adenosylmethionine formulations  
Compositions and methods to improve the pharmacokinetic profile of S-Adenosylmethionine (SAMe) are provided, as are methods of treating various disorders using SAMe formulations with improved...
8329673 Alkylated semi synthetic glycosaminoglycosan ethers, and methods for making and using thereof  
Described herein are alkylated and semi-synthetic glycosaminoglycosan ethers, referred to herein as “SAGEs.” The synthesis of sulfated and alkylated SAGEs is also described. The compounds des...
8323669 Polymer conjugate of taxane  
[Problems] To provide a novel taxane derivative which can release the medicinal substance in a bioenzyme-independent manner, is expected to have an effective therapeutic efficacy, and has a...
8323670 Topical compositions of opioid antagonists and methods for treating skin conditions therewith  
Provided are topical compositions comprising opioid antagonists, such as naltrexone or naloxone, or their pharmaceutically acceptable salts, and methods for treating skin conditions, such as those...
8323641 Nanoparticulate compositions having lysozyme as a surface stabilizer  
The present invention is directed to nanoparticulate active agent compositions comprising lysozyme as a surface stabilizer. Also encompassed by the invention are pharmaceutical compositions...
8318818 Topical composition, topical composition precursor, and methods for manufacturing and using  
A tropical composition is provided. The topical composition can be prepared by diluting a topical composition precursor with water and adding additional components, if desired. The topical...
8318788 Layered pharmaceutical formulations  
In one embodiment a layered pharmaceutical formulation includes two or more pharmaceutical layers and an intermediate layer disposed between at least two of the two or more pharmaceutical layers,...
8318136 Methods and systems for neural maintenance and regeneration  
Methods and systems are described that release one or both of a neurotrophin and an inhibitor of the degradation of the neurotrophin within or in the vicinity of a highly innervated tissue. In some...
8318210 Compositions and methods of making sustained release liquid formulations  
The present invention includes compositions and methods for the controlled release of active agents in a shelf-stable liquid formulation by blending one or more controlled release microbeads...
8318961 Oligomers of cholesterol, cholesterol sulphate and cholesterol esters and also drugs containing these  
The invention relates to new substances which are derived from cholesterol, cholesterol sulphate and cholesterol esters of a natural, semi-synthetic or synthetic origin in that they represent...
8318898 Synthetic peptides for use as inhibitors of neurotransmitter secretion and as inducers of cellular relaxation  
The present invention describes materials and methods related to synthetic peptides which block the secretion of neurotransmitters and induce muscle relaxation, and use of said peptides as...