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8431221 Therapeutic calcium phosphate particles and methods of manufacture and use  
Novel calcium phosphate core particles, methods of making them, and methods of using them as vaccine adjuvants, as cores, as carriers of biologically active material, and as controlled release...
8426466 Compositions and methods for enhancing active agent absorption  
Compositions and methods for enhancing the absorption of active agents across the mucosa of animal subjects are provided. Methods of administration and appropriate dosage forms are also provided.
8425923 Lotion composition for personal use  
This invention relates to emulsion compositions that can warm on contact with ambient moisture and can be used as lubricants on the skin of a person. They may be formulated in the form of a lotion...
8425879 Metalloporphyrin derivatives, nanoparticles comprising the same, and use thereof for photodynamic therapy  
Nanovectors are disclosed that make it possible to simultaneously target, image, and treat cancerous cells using photodynamic therapy. Also disclosed are novel molecules (I) derived from...
8420108 Flexible bone composite  
The present invention relates in general to implantable flexible bone composites, and method for preparing the same. The flexible bone composite includes at least one polymeric layer and at least...
8420057 Capsule having broad color spectrum  
The present invention is directed to a capsule comprising a water-soluble compound suitable for the capsule, a non-water soluble excipient suitable for the capsule; and suitable for the capsule,...
8420851 Selective TR-β 1 agonist  
The present invention relates to novel compounds of general formula (I) which are thyroid receptor ligands and are preferably selective for the thyroid hormone receptor beta (TR-Beta). Further, the...
8420662 Stable solid preparation containing 4,5-epoxymorphinan derivative  
It is an object of the present invention to provide a stable solid preparation comprising a 4,5-epoxymorphinan derivative or a pharmacologically acceptable acid addition salt thereof as an...
8420105 Botulinum toxin administration to treat various conditions  
Methods for treating conditions in an animal or human subject. The conditions may be pain, skeletal muscle conditions, smooth muscle conditions, glandular conditions and cosmetic conditions. The...
8420126 Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment  
Compositions having a combination of specific biological components have been found to exert a number of useful effects in mammalian cells, including modulating TGF β signaling, apoptosis, and ...
8414958 Implant and method for the manufacture thereof  
What is described is an implant that comprises a coating, at least in areas, in the implanted state in the surface areas that are at least directly in contact with skin and/or soft tissue. The...
8415390 Methods and compositions for administration of oxybutynin  
Administration of Oxybutynin directly to a patient's lungs for treating urinary incontinence, respiratory disease or IBD.
8414904 Ophthalmic oil-in-water emulsions containing prostaglandins  
The present invention refers to an oil-in-water emulsion for ophthalmic application comprising at least one prostaglandin as active agent and a surfactant component comprising a combination of at...
8414905 Film coating compositions based on polyvinyl alcohol-polyether graft copolymer/polyvinyl alcohol combinations with an improved moisture barrier effect  
Film coating compositions based on a co-processed mixture of a polyvinyl alcohol-polyether graft polymer and polyvinyl alcohol (component A), a N-vinylpyrrolidone-vinyl acetate copolymer (component...
8414873 Blood vessel stent of amidoglucosan polysaccharide loaded with CD133 antibody and its preparation method  
A blood vessel metal stent coating of amidoglucosan polysaccharide loaded with antibody comprises carrier material composed of chitosan and inartificial degradable acidic amidoglucosan...
8415342 Besifloxacin ophthalmic composition for the treatment or control of infection  
A composition comprises besifloxacin in an amount effective for treating or controlling an infection caused by an antibiotic-resistant bacterium. Such a composition can be administered to a subject...
8409616 Extended release opioid abuse deterrent compositions and methods of making same  
This invention relates to an abuse deterrent dosage form of opioid analgesics, wherein an analgesically effective amount of opioid analgesic is combined with a polymer to form a matrix.
8409594 Solid oil-in-water emulsion  
The present invention aims to provide solid compositions comprising an oil-in-water emulsion that have sufficient hardness and good feel when used, and can sufficiently exhibit the physiological...
8410079 Chirally correct retinal cyclodextrin hemiacetals for clarifying skin complexion  
The present invention discloses certain chirally correct polyene cyclodextrin acetals and hemiacetals (formula I) that are effective in providing skin clarification, which is useful for the...
8409593 Methods for reducing tackiness associated with a xanthine compound  
The invention relates to a composition containing, preferably in a physiologically acceptable medium, at least one xanthine base or a plant extract containing it, at least one polyurethane powder,...
8404300 Drug releasing coatings for medical devices  
The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a...
8404270 Method of reducing incidence of intraocular pressure associated with intraocular use of corticosteroids  
A method of treating an ocular disease in a subject using a corticosteroid with reduced incidence of intraocular pressure lowering surgery comprises injecting an intravitreal insert capable of...
8404645 Stable formulations of amylin and its analogues  
The invention relates to a soluble pharmaceutical composition for parenteral administration, which comprises an amylin peptide and an anionic surfactant, and methods for treatment of hyperglycemia.
8404256 Biomaterial composite composition and method of use  
This invention relates to a process to facilitate osteochondral bone remodeling in a subject by inducing regeneration of this bone to a healthy, vascularized state capable of supporting the...
8404255 System and method for transdermal drug delivery  
In the preferred embodiment, the invention is a system for creating micropores in the skin for transdermal drug delivery through the micropores and includes: a chemical that dissolves or breaks...
8398967 Particle formulations for use in pharmaceutical compositions  
A liquid composition in an osmotic drug delivery system and a dosage form in an osmotic drug delivery system is disclosed comprising an amphiphilic molecule, a non-aqueous liquid solvent, and a...
8399019 Oral delivery vehicle and material  
Compositions for an oral delivery vehicle are described as well as methods for their manufacture and administration. The oral delivery vehicles can be made in any size or shape and can further...
8398957 Aerosol compositions  
An aerosol composition comprising: 0.01 wt % to 1.00 wt % sodium borate; 0.01 wt % to 1.50 wt % polyglycerol ester surfactant; <30 wt % propellant; and 67.5 wt % to 85.0 wt % water. Methods of...
8394401 Antiobesity or antihyperlipidemic food, feeding stuff or supplement containing lysine  
In this application, an antiobesity or antihyperlipidemic food, feeding stuff or supplement containing lysine component(s) that is characterized in that said food, feeding stuff or supplement...
8394391 Drug delivery vehicle that mimics viral properties  
A drug delivery vehicle for targeted delivery of a drug mimics viral properties of size, capsid-like protein capsule, cell-specific entry, toxin release, destruction of infected cells, and...
8394494 Antimicrobial substrates and uses thereof  
A new substrate makes it possible to modify surface properties relating to antimicrobial properties. Said substrate has an electron donating surface, characterized in having metal particles on said...
8394393 System and method for the release of nitric oxide using nanoscale media  
A composite material containing polymeric nanofibers, themselves containing NO-donor molecules, imbibed with an elastomer matrix is permeable to both water and gas so that dissociation reactions in...
8394392 Antibacterial agent composed of silver-containing aluminum sulfate hydroxide particles and use thereof  
An antibacterial agent composed of silver-containing aluminum sulfate hydroxide particles represented by the following formula (X-I) or (Y-I). (AgaBb-a)bAlcAx(SO4)y(OH)z.pH2O (X-I)...
8389006 Pharmaceutical compositions of adsorbates of amorphous drug  
Pharmaceutical compositions comprise a low-solubility drug adsorbed onto a high surface area substrate to form an adsorbate. The compositions in some embodiments include a concentration-enhancing...
8389004 Process for producing protein microparticles  
The present invention relates to a process for producing protein microparticles in dilute organic acid solutions and in the absence of an alcohol such as ethanol. The microparticles are formed by...
8388993 Hyaluronan-chemotherapeutic agent formulations for the treatment of colon cancer  
The present invention relates to the enhancement of bioavailability of chemotherapeutic agents for the treatment of disease. In particular, the present invention relates to a method of enhancing...
8388992 Anti-microbial hand towel with time-delay chromatic transfer indicator and absorbency rate delay  
A disposable paper towel with an anti-microbial lotion and is provided with a chromatic transfer indicator which undergoes a delayed, visually perceptible color change at a predetermined time after...
8388984 Site-specific intestinal delivery of adsorbents, alone or in combination with degrading molecules  
Compositions which deliver adsorbents, alone or in combination with active drug “degrading molecules,” in a site-specific manner to the intestine, and which eliminate or at least lower the con...
8388982 Photo-induced damage mitigating agents and preparation and methods of use thereof  
Compositions, devices, systems and methods for reducing and/or preventing photo-induced damage of one or more reactants in an illuminated analytical reaction by addition of one or more...
8389005 Systemic treatment of pathological conditions resulting from oxidative stress and/or redox imbalance  
Alterations of redox homeostasis in mammals underlie a host of symptoms, syndromes and diseases, including AIDS and cancer, which can be successfully treated by administration to a mammal of...
8388983 Film coatings containing fine particle size detackifiers and substrates coated therewith  
The present invention is directed to film coating compositions for use on oral dosage forms such as compressed tablets and other orally-ingestible substrates which contain a fine particle size...
8388985 Easily dispersible lipidic phase  
The present invention relates to the use of a lipidic phase comprising an oil and a lipophilic additive (LPA), which is suitable to make an oil-in-water emulsion by application of low energy or a...
8389768 Methods and compositions comprising novel cationic lipids  
Provided herein are novel cationic lipids, compositions comprising the cationic lipids, and methods of using the cationic lipids. In some claims, the cationic lipids have cytotoxic activity and can...
8388997 Method of preparing an unsaturated fatty acid dry concentrate  
There is provided a method of preparing an unsaturated fatty acid dry concentrate, wherein a substance comprising at least one unsaturated fatty acid is applied on a biologically inert matrix...
8383090 Cleansing composition based on oily substances  
A cleansing composition based on oily substances, particularly for cleansing skin and/or hair and having excellent dermatological properties, is described. The composition is characterized in that...
8383136 Micelle encapsulation of therapeutic agents  
The invention provides active agents, such as paclitaxel, rapamycin, or 17-AAG, encapsulated by safe poly(ethylene glycol)-block-poly(lactic acid) (“PEG-b-PLA”) micelles. The compositions pro...
8383135 Solid dosage form that promotes reliable oral, esophageal and GI transit  
A solid dosage form designed to facilitate rapid and reliable oral, esophageal and GI transit has a surface area of the contact patch, i.e., the area of contact between the dosage form and the...
8383134 Biodegradable material based on opened starch  
The present application relates to a biodegradable material comprising opened starch or a mixture of opened starch and destructurised starch. The biodegradable material comprises about 50 to about...
8377457 Naturally derived glyceryl dimer polyesters having liquid and solid domains  
The present invention is directed to a series of polymeric glyceryl esters that have two different molecular weight ester chains, one solid and one liquid, which when combined into a single...
8377454 Treating male infertility secondary to sperm oxidative stress  
A profertility composition for administration to infertile men with sperm oxidative stress is disclosed. The composition comprises a unique combination of a pharmaceutically acceptable vitamin E,...