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8445015 Extended-release formulation for reducing the frequency of urination and method of use thereof  
Methods and compositions for reducing the frequency of urination are disclosed. One method comprises administering to a subject in need thereof an effective amount of a pharmaceutical composition...
8445002 Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same  
Dermal delivery compositions are provided. Aspects of the dermal delivery compositions include the presence of active agent-calcium phosphate particle complexes, where these complexes include...
8445528 Dendrimer conjugates  
The present invention relates to novel therapeutic and diagnostic dendrimers. In particular, the present invention is directed to dendrimer-linker conjugates, methods of synthesizing the same,...
8445003 Stable pharmaceutical composition and methods of using same  
The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular related diseases.
8445020 High-loading, controlled-release magnesium oral dosage forms and methods of making and using same  
Disclosed are high-loading, controlled-release dosage forms for oral administration of magnesium salts. For example, an oral dosage form can comprise from about 80% to about 95% magnesium lactate...
8440210 Stabilized pharmaceutical product  
Use of an adsorbent and a sealed package (e.g. an overwrap) to protect a pharmaceutical product in a solid state in the presence of a reducing sugar.
8440232 Methods of treatment using a gastric retained gabapentin dosage  
A method of treatment for epilepsy and other disease states is described, which comprises delivery of gabapentin in a gastric retained dosage form.
8440235 Amniotic membrane preparations and purified compositions and therapy for scar reversal and inhibition  
Compositions having a combination of specific biological components have been found to exert a number of useful effects in mammalian cells, including modulating TGF β signaling, apoptosis, and ...
8440217 Method and system with contact lens product for treating and preventing adverse eye conditions  
A contact lens product, a method and system for forming the contact lens product, and a method of using the contact lens product. The contact lens product includes a soft disposable contact lens...
8440209 Adhesive for medical applications and means for haemostasis  
The invention relates to adhesives for medical applications and methods of their preparation and use.
8435551 Cancellous construct with support ring for repair of osteochondral defects  
The invention is directed toward an osteochondral repair assembly comprising a shaped allograft construct comprising an unbalanced barbell-shaped cylindrical cancellous bone primary member formed...
8435502 Cosmetic/dermatological compositions comprising naphtholic acid compounds and polyurethane polymers  
Cosmetic/dermatological compositions for topical application and useful for the treatment, e.g., of acne, contain, formulated into a physiologically acceptable medium, at least one naphthoic acid...
8435544 Ophthalmic compositions comprising calcineurin inhibitors or mTOR inhibitors  
The embodiments disclosed herein relate to ophthalmic compositions comprising calcineurin inhibitors or mTOR inhibitors, and more particularly to methods for treating an ocular disease and/or...
8435545 Capsule having broad color spectrum  
The present invention is directed to a capsule comprising a water-soluble compound suitable for the capsule, and a mixture of colorant agents, wherein the color of the capsule may be in the range...
8435500 Nail whitening composition  
A cosmetic composition for bleaching discolored nails containing at least one hydrogen peroxide generator in an amount sufficient to perform bleaching of discolored nails, at least one film forming...
8435553 Elastin stabilization of connective tissue  
A method and product are provided for the treatment of connective tissue weakened due to destruction of tissue architecture, and in particular due to elastin degradation. The treatment agents...
8431143 Therapeutic method of administering pharmaceutical titanium dioxide composite and light irradiation  
A titanium dioxide composite is provided that can be stably dispersed in an aqueous solvent and easily administered into a living body, such as human, and allows elimination of the drug efficacy of...
8431221 Therapeutic calcium phosphate particles and methods of manufacture and use  
Novel calcium phosphate core particles, methods of making them, and methods of using them as vaccine adjuvants, as cores, as carriers of biologically active material, and as controlled release...
8426466 Compositions and methods for enhancing active agent absorption  
Compositions and methods for enhancing the absorption of active agents across the mucosa of animal subjects are provided. Methods of administration and appropriate dosage forms are also provided.
8425923 Lotion composition for personal use  
This invention relates to emulsion compositions that can warm on contact with ambient moisture and can be used as lubricants on the skin of a person. They may be formulated in the form of a lotion...
8425879 Metalloporphyrin derivatives, nanoparticles comprising the same, and use thereof for photodynamic therapy  
Nanovectors are disclosed that make it possible to simultaneously target, image, and treat cancerous cells using photodynamic therapy. Also disclosed are novel molecules (I) derived from...
8420108 Flexible bone composite  
The present invention relates in general to implantable flexible bone composites, and method for preparing the same. The flexible bone composite includes at least one polymeric layer and at least...
8420057 Capsule having broad color spectrum  
The present invention is directed to a capsule comprising a water-soluble compound suitable for the capsule, a non-water soluble excipient suitable for the capsule; and suitable for the capsule,...
8420851 Selective TR-β 1 agonist  
The present invention relates to novel compounds of general formula (I) which are thyroid receptor ligands and are preferably selective for the thyroid hormone receptor beta (TR-Beta). Further, the...
8420662 Stable solid preparation containing 4,5-epoxymorphinan derivative  
It is an object of the present invention to provide a stable solid preparation comprising a 4,5-epoxymorphinan derivative or a pharmacologically acceptable acid addition salt thereof as an...
8420105 Botulinum toxin administration to treat various conditions  
Methods for treating conditions in an animal or human subject. The conditions may be pain, skeletal muscle conditions, smooth muscle conditions, glandular conditions and cosmetic conditions. The...
8420126 Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment  
Compositions having a combination of specific biological components have been found to exert a number of useful effects in mammalian cells, including modulating TGF β signaling, apoptosis, and ...
8414958 Implant and method for the manufacture thereof  
What is described is an implant that comprises a coating, at least in areas, in the implanted state in the surface areas that are at least directly in contact with skin and/or soft tissue. The...
8415390 Methods and compositions for administration of oxybutynin  
Administration of Oxybutynin directly to a patient's lungs for treating urinary incontinence, respiratory disease or IBD.
8414904 Ophthalmic oil-in-water emulsions containing prostaglandins  
The present invention refers to an oil-in-water emulsion for ophthalmic application comprising at least one prostaglandin as active agent and a surfactant component comprising a combination of at...
8414905 Film coating compositions based on polyvinyl alcohol-polyether graft copolymer/polyvinyl alcohol combinations with an improved moisture barrier effect  
Film coating compositions based on a co-processed mixture of a polyvinyl alcohol-polyether graft polymer and polyvinyl alcohol (component A), a N-vinylpyrrolidone-vinyl acetate copolymer (component...
8414873 Blood vessel stent of amidoglucosan polysaccharide loaded with CD133 antibody and its preparation method  
A blood vessel metal stent coating of amidoglucosan polysaccharide loaded with antibody comprises carrier material composed of chitosan and inartificial degradable acidic amidoglucosan...
8415342 Besifloxacin ophthalmic composition for the treatment or control of infection  
A composition comprises besifloxacin in an amount effective for treating or controlling an infection caused by an antibiotic-resistant bacterium. Such a composition can be administered to a subject...
8409616 Extended release opioid abuse deterrent compositions and methods of making same  
This invention relates to an abuse deterrent dosage form of opioid analgesics, wherein an analgesically effective amount of opioid analgesic is combined with a polymer to form a matrix.
8409594 Solid oil-in-water emulsion  
The present invention aims to provide solid compositions comprising an oil-in-water emulsion that have sufficient hardness and good feel when used, and can sufficiently exhibit the physiological...
8410079 Chirally correct retinal cyclodextrin hemiacetals for clarifying skin complexion  
The present invention discloses certain chirally correct polyene cyclodextrin acetals and hemiacetals (formula I) that are effective in providing skin clarification, which is useful for the...
8409593 Methods for reducing tackiness associated with a xanthine compound  
The invention relates to a composition containing, preferably in a physiologically acceptable medium, at least one xanthine base or a plant extract containing it, at least one polyurethane powder,...
8404300 Drug releasing coatings for medical devices  
The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a...
8404270 Method of reducing incidence of intraocular pressure associated with intraocular use of corticosteroids  
A method of treating an ocular disease in a subject using a corticosteroid with reduced incidence of intraocular pressure lowering surgery comprises injecting an intravitreal insert capable of...
8404645 Stable formulations of amylin and its analogues  
The invention relates to a soluble pharmaceutical composition for parenteral administration, which comprises an amylin peptide and an anionic surfactant, and methods for treatment of hyperglycemia.
8404256 Biomaterial composite composition and method of use  
This invention relates to a process to facilitate osteochondral bone remodeling in a subject by inducing regeneration of this bone to a healthy, vascularized state capable of supporting the...
8404255 System and method for transdermal drug delivery  
In the preferred embodiment, the invention is a system for creating micropores in the skin for transdermal drug delivery through the micropores and includes: a chemical that dissolves or breaks...
8398967 Particle formulations for use in pharmaceutical compositions  
A liquid composition in an osmotic drug delivery system and a dosage form in an osmotic drug delivery system is disclosed comprising an amphiphilic molecule, a non-aqueous liquid solvent, and a...
8399019 Oral delivery vehicle and material  
Compositions for an oral delivery vehicle are described as well as methods for their manufacture and administration. The oral delivery vehicles can be made in any size or shape and can further...
8398957 Aerosol compositions  
An aerosol composition comprising: 0.01 wt % to 1.00 wt % sodium borate; 0.01 wt % to 1.50 wt % polyglycerol ester surfactant; <30 wt % propellant; and 67.5 wt % to 85.0 wt % water. Methods of...
8394401 Antiobesity or antihyperlipidemic food, feeding stuff or supplement containing lysine  
In this application, an antiobesity or antihyperlipidemic food, feeding stuff or supplement containing lysine component(s) that is characterized in that said food, feeding stuff or supplement...
8394391 Drug delivery vehicle that mimics viral properties  
A drug delivery vehicle for targeted delivery of a drug mimics viral properties of size, capsid-like protein capsule, cell-specific entry, toxin release, destruction of infected cells, and...
8394494 Antimicrobial substrates and uses thereof  
A new substrate makes it possible to modify surface properties relating to antimicrobial properties. Said substrate has an electron donating surface, characterized in having metal particles on said...
8394393 System and method for the release of nitric oxide using nanoscale media  
A composite material containing polymeric nanofibers, themselves containing NO-donor molecules, imbibed with an elastomer matrix is permeable to both water and gas so that dissociation reactions in...
8394392 Antibacterial agent composed of silver-containing aluminum sulfate hydroxide particles and use thereof  
An antibacterial agent composed of silver-containing aluminum sulfate hydroxide particles represented by the following formula (X-I) or (Y-I). (AgaBb-a)bAlcAx(SO4)y(OH)z.pH2O (X-I)...