Sign up


Match Document Document Title
7323183 Vaccine compositions including chitosan for intranasal administration and use thereof  
There is provided vaccine compositions for intranasal administration, which compositions comprise one or more antigens and an effective adjuvant amount of a chitosan.
7323182 Oil in water emulsions containing saponins  
The present invention relates to an oil in water emulsion vaccine composition. In particular, the present invention relates to a vaccine adjuvant formulation based on oil in water emulsion...
7320793 Molecular antigen array  
The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or...
7314626 Use of peptide vectors to improve the immune response to antigens  
The invention relates to conjugates of an antigen coupled to a linear derivative of a β-stranded antibiotic peptide, which are useful for immunogenic agents to enhance a CTL response. Two groups ...
7314627 Cationic lipid-mediated enhancement of nucleic acid immunization of cats  
The present invention relates to a method to introduce a nucleic acid molecule into a felid by administration of a nucleic acid-cationic lipid complex composition. The method includes the step of...
7297761 Pharmaceutical compositions containing exendins  
Methods for treating conditions or disorders which can be alleviated by reducing food intake are disclosed which comprise administration of an effective amount of an exendin or an exendin agonist,...
7291588 Immunogenic detoxified mutant E. coli LT-A toxin  
An immunogenic detoxified protein is provided which comprises the amino acid sequence of subunit A of an E. coli heat labile toxin (LT-A) or a fragment thereof in which at least amino acid Ala-72...
7288261 Mid-life vaccine and methods for boosting anti-mycobacterial immunity  
Vaccine compositions for boosting immunity to mycobacteria when administered in mid-life in a subject who has been vaccinated neonatally or in early childhood with BCG and in whom protective...
7285282 Mucin peptide with immunoenhancing properties  
An isolated peptide or polypeptide containing the sequence VSIGLSFPMLP (SEQ ID NO:1), found in the secreted form of human MUC1, that enhances an immune response when administered to a mammal,...
7285289 Nanoparticle vaccines  
The present invention relates to nanoparticle vaccines comprised of a carrier, particularly polymerized lipids, having multiple copies of an antigen or combinations of different antigens displayed...
7279172 Treatment of autoimmune conditions with copolymer 1 and related copolymers  
The present invention provides heteropolymer compositions and peptide compositions, and methods of making and using therapeutic compositions comprising amino acid heteropolymers for treatment of a...
7273615 Reaction solution for cell-free protein synthesis, method of preparing the same, and protein synthesis method using the same  
The present invention provides a cell-free protein synthesis method characterized by a cell-free protein synthesis reaction solution that is weakly reducing and suitable for protein folding,...
7270820 CD4+ T-lymphocyte-specific hepatitis C virus epitopes  
The invention relates to hepatitis C virus epitopes which are CD4+ T-lymphocyte specific, and to vaccines containing these epitopes.
7267822 Cytomodulating lipophilic peptides for modulating immune system activity and inhibiting inflammation  
Novel oligonucleotides comprising a sequence derived by a computer program are provided for inhibiting cytotoxic activity of lymphocytic cells, inhibiting production of inflammatory cytokines and...
7262167 Drug, in particular for modulating the immunological response for the control of viruses, tumors, bacteria and parasites  
A method of treating tumors and other conditions in a patient is provided. The method involves administering to the patient a treatment medicament. The medicament contains a first component and a...
7262014 Immune responses against HPV antigens elicited by compositions comprising an HPV antigen and a stress protein or an expression vector capable of expression of these proteins  
This document describes compositions and methods for inducing an immune response (e.g., a cellular response such as a cell-mediated cytolytic immune response) to a human papillomavirus (HPV)...
7259137 Peptides and related molecules that bind to TALL-1  
The present invention concerns therapeutic agents that modulate the activity of TALL-1. In accordance with the present invention, modulators of TALL-1 may comprise an amino acid sequence Dz2Lz4...
7259136 Compositions and methods for treating peripheral vascular disease  
The present invention relates to methods of treating intermittent claudication comprising administering glucagon-like peptide-1 (GLP-1) molecules to subjects suffering therefrom.
7244438 Uses for polycationic compounds  
The invention relates to the use of a polycationic compound for the preparation of a medicament with retarded in vivo release.
7244412 Methods for manipulating upper gastrointestinal transit, blood flow, and satiety, and for treating visceral hyperalgesia  
Disclosed is a method of manipulating the rate of upper gastrointestinal transit of a substance in a mammal. Also disclosed are methods of manipulating satiety and post-prandial visceral blood...
7244818 Interferon alpha responsive protein  
The present invention relates to identification of a gene upregulated by interferon-α administration corresponding to the cDNA sequence set forth in SEQ ID NO: 1. Determination of expression ...
7244425 Acid- and bile salt-resistant Lactobacillus isolates having the ability to lower and assimilate cholesterol  
Disclosed are acid- and bile salt-resistant Lactobacillus isolates having the ability to lower cholesterol. The present Lactobacillus isolates or their sub-cultured offspring or mutants derived...
7241867 Polypeptide encoded by a nucleotide sequence of a nontypeable strain of Haemophilus influenzae genome  
The invention relates to the polynucleotide sequence of a nontypeable stain of Haemophilus influenzae (NTHi) and polypeptides encoded by the polynucleotides and uses thereof. The invention also...
7229621 Method to enhance the immunogenicity of an antigen  
The present invention is related to a method for enhancing the immunogenicity of an antigen in a mammal by introducing into the mammal an antigen or a portion thereof and administering to the...
7229628 Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling  
T cell activation in response to antigen is increased by the administration of binding agents that block CTLA-4 signaling. When CTLA-4 signaling is thus blocked, the T cell response to antigen is...
7229646 Methods and compositions for modulating immune response and for the treatment of inflammatory disease  
Compositions and methods for treating inflammatory disease and for modulating the immune system are described. The compositions and methods pertain to the use of a combination of...
7223739 Adjuvanted genetic vaccines  
Reagents useful in nucleic acid immunization techniques are described. More particularly, adjuvanted genetic vaccine compositions are described, as are methods of using those compositions for...
7223391 Method for treating mammals with modified mammalian blood  
An improved method for treating or preventing a pathological condition in a mammalian subject in which modified mammalian blood is administered to the subject. The method comprises administering to...
7217700 Chemokines as adjuvants of immune response  
Dendritic cells play a critical role in antigen-specific immune responses. Materials and methods are provided for treating disease states, including cancer and autoimmune disease, by facilitating...
7208167 Treatment of hepatitis C with thymosin and peptide combination therapy  
A method and pharmaceutical combination for treating hepatitis C by administering to a hepatitis C patient an effective amount of at least one alpha thymosin peptide, in combination with...
7195763 Surface proteins from gram-positive bacteria having highly conserved motifs and antibodies that recognize them  
Isolated peptide sequences and proteins containing these sequences are provided which are useful in the prevention and treatment of infection caused by Gram-positive bacteria. The peptide sequences...
7192927 Peptides  
Isolated peptides that are fragments of protein products arising from frameshift mutations in genes associated with cancer are disclosed. The isolated peptides of the invention are capable of...
7189834 Oligoribonucleotides alert the immune system of animals to the imminence of microbial infection  
This invention provides novel methods and compositions for modulating and stimulating the immune system of animals to withstand microbial infections and the lethality of endotoxic shock by feeding...
7182962 Immunostimulator for animals and humans, and method of preventing animal and human infectious diseases and cancer  
The goal of the present invention is to provide substances to prevent diseases by activating inherently possessed functions, for cultured fishes and shellfishes and livestock with tendency of...
7183108 Selection and uses of lactic acid bacteria strains modulating non-specific immunity  
The invention concerns lactic acid bacteria strains capable of regulating the production of NO and inflammatory cytokines by enterocytes, depending on the inflammatory condition of said...
7182948 Topical veterinary compositions and methods for the treatment and prevention of infection  
The present invention provides compositions and methods for the treatment of infection in a subject. More particularly, the invention provides a therapy for the treatment or prevention of mammary...
7179471 Materials and methods relating to fusion proteins an immune response  
A nucleic acid construct is provided for delivery into living cells in vivo for inducing an immune response in a patient to an antigen; the construct directing the expression of a fusion protein,...
7169395 Multivalent immunogenic composition containing RSV subunit composition and influenza virus preparation  
Immunogenic compositions for administration to adults, particularly to the elderly, to protect them against disease caused by infection by respiratory syncytial virus and by influenza virus...
7169399 Non-toxic double mutant forms of pertussis toxin as adjuvants  
The invention relates to the use of an antigen which is a non-toxic double mutant form of pertussis toxin for the manufacture of a vaccine composition for intranasal administration to induce an...
7163703 Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds  
The invention relates to the use of arsenic compounds to treat a variety of neoplastic diseases. The present invention encompasses the administration to a mammal of arsenic in the form of a salt,...
7163810 Method for producing target substance  
In a method for producing a target substance by using a microorganism comprising culturing a microorganism having an ability to produce the target substance in a medium to produce and accumulate...
7157092 Acyl pseudodipeptides, preparation method and pharmaceutical compositions containing same  
Compounds of the formula wherein the substitutents are defined as in the specification useful for modulating immune responses in warm-blooded animals.
7153509 Immunogenic peptides comprising a T-helper epitope and a B-cell neutralizing antibody epitope  
The present invention relates, generally, to a polyvalent immunogen and, more particularly, to a method of inducing neutralizing antibodies against HIV and to a polyvalent immunogen suitable for...
7147849 Pharmaceutical formulation  
A pharmaceutical formulation containing at least one protein-containing substance and at least one substance selected from the group of compatible solutes.
7147862 Vaccine composition containing adjuvants  
The present invention provides vaccine compositions comprising 3 De-O-acylated monophosphoryl lipid A and QS21. The vaccines compositions are potent inducers of CTL and γ IFN responses.
7129334 Synthetic peptide and uses for same  
Beta taipoxin obtained the taipoxin component of the venom of the taipan snake, Oxyuranus s. scutellatus, was fragmented by trypsin digestion. The fragment which showed the highest activity on skin...
7125556 Nucleic acid molecule comprising a nucleic acid sequence coding for a haemocyanin  
A nucleic acid molecule or construct alone or with a promoter suitable for expression control is contemplated that codes for a haemocyanin, a haemocyanin domain or a fragment thereof with the...
7122191 Microfluidized oil-in-water emulsions and vaccine compositions  
This invention provides submicron oil-in-water emulsions useful as a vaccine adjuvant for enhancing the immunogenicity of antigens. The present invention also provides vaccine compositions...
7122192 Porcine circoviruses, vaccines and diagnostic reagents  
The invention relates to new porcine circovirus strains isolated from pulmonary or ganglionic samples obtained from farms affected by the post-weaning multisystemic wasting syndrome (PMWS). It...
7122620 Haptotactic peptides  
This invention is related to a novel peptide consisting of the amino acid sequence of SEQ ID NO:1, and a pharmaceutical composition comprising the peptide thereof.