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7384638 |
Compounds and methods for treatment and diagnosis of Chlamydial infection
Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia ...
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7361353 |
Immunisation against Chlamydia trachomatis
The present invention provides antigenic proteins of Chlamydia trachomatis . The proteins of the present invention are useful for eliciting an immune response to Chlamydia in a patient. For...
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7335370 |
Chlamydia antigens and corresponding DNA fragments and uses thereof
The present invention provides a method of immunizing a host against disease caused by infection by a strain of Chlamydia , specifically C. pneumoniae . The method involves nucleic acid...
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7279171 |
Vaccines for Chlamydia psittaci infections
Vaccine compositions protective against Chlamydia psittaci infections in animals, including but not limited to humans and avian species, comprising an immunogenic amount of a C. psittaci major...
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7223836 |
Peptides for chlamydophila pneumoniae vaccine and diagnosis
Peptides are disclosed that include SEQ ID NO:1, SEQ ID NO: 2, SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, and SEQ ID NO:6, or a conservative variant or mimic thereof, wherein the conservative variant...
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7166289 |
Nucleic acid molecules encoding inclusion membrane protein C of Chlamydia
The present invention provides a method of nucleic acid, including DNA, immunization of a host, including humans, against disease caused by infection by a strain of Chlamydia , specifically C....
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7132512 |
Medicament for the treatment of chlamydial infection
The present invention concerns treatment, prevention and diagnosis of infection due to Chlamydia pneumoniae and, in particular, to the prevention and treatment of atherosclerosis, including...
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7105171 |
Porin B (PorB) as a therapeutic target for prevention and treatment of infection by Chlamydia
The present invention features peptides of a PorB polypeptide, which PorB peptides are useful in production of antibodies that bind the full-length PorB polypeptide and as a therapeutic agent. In...
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7094391 |
Compositions and methods for administering Borrelia burgdorferi antigens
Mucosal administration of OspA and compositions therefor are disclosed and claimed. More particularly, oral administration of OspA and compositions therefor for eliciting an immunological response...
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7070791 |
Detection of antibodies against Chlamydia trachomatis pgp3 antigen in patient sera by enzyme-linked immunoassay
A new recombinant form of the plasmid-encoded protein pgp3 from C. trachomatis , serotype D, was purified by ion exchange column chromatography and shown to be suitable for quantitative immunoassy...
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7063853 |
DNA immunization against Chlamydia infection
Nucleic acid, including DNA, for immunization to generate a protective immune response in a host, including humans, to a major outer membrane protein of a strain of Chlamydia , preferably contains...
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6846487 |
Therapeutic compositions for treating infection by Lawsonia spp.
The present invention relates generally to therapeutic compositions for the treatment and/or prophylaxis of intestinal disease conditions in animals and birds caused or exacerbated by Lawsonia...
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6814971 |
Adjuvants for use in vaccines
The invention relates to adjuvants that contain a lecithin, an oil and an amphiphilic surfactant and that are capable of forming a stable oil-in-water emulsion vaccine so as to minimize local...
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6746676 |
Chlamydia proteins and their uses
Certain Chlamydia proteins have been found to be infection-specific and to be associated primarily with the vegetative Reticulate Body form of Chlamydia rather than with the refractile Elementary...
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6699678 |
Chlamydia trachomatis specific peptides and their use in diagnostic assays
Disclosed are peptides or a mixture of peptides, or analogs thereof, derived from the variable domains of the Chlamydia trachomatis ( C. trachomatis ) immunodominant major outer membrane protein...
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6676949 |
Two-step immunization procedure against Chlamydia infection
A host is immunized against infection by a strain of Chlamydia by initial administration of an attenuated bacteria harbouring a nucleic acid encoding a Chlamydia protein followed by administration...
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6649374 |
Recombinant Chlamydia trachomatis PGP3 antigen
A new recombinant form of the plasmid-encoded protein pgp3 from C. trachomatis , serotype D, to be used in immunogenic compositions and in the preparation of immunogenic compositions was purified...
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6565856 |
Compounds and methods for treatment and diagnosis of chlamydial infection
Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia...
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6555115 |
Compounds and methods for treatment and diagnosis of chlamydial infection
Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia...
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6491924 |
Chlamydia pneumoniae antigenic polypeptide
Chlamydia pneumoniae antigenic polypeptides, which comprise polypeptide A containing a sequence of at least 5 consecutive amino acids in the polypeptide of SEQ ID NO: 1; DNAs encoding the...
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6489122 |
Method of detecting anti-Chlamydia pneumoniae antibody using Chlamydia pneumoniae-specific antigens
Chlamydia pneumoniae antigenic polypeptides, which comprise polypeptide A containing a sequence of at least 5 consecutive amino acids in the polypeptide of SEQ ID NO: 1, DNAs encoding the...
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6485914 |
Method of detecting chlamydia pneumoniae gene using polynucleotides
Chlamydia pneumoniae antigenic polypeptides, which comprise polypeptide A containing a sequence of at least 5 consecutive amino acids in the polypeptide of SEQ ID NO: 1; DNAs encoding the...
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6464979 |
Chlamydial vaccines and methods of preparation thereof
Immunogenic compositions including vaccines are described that comprise an outer membrane antigen extract of a strain of Chlamydia and are effective in protection against disease caused by...
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6448234 |
Compounds and methods for treatment and diagnosis of chlamydial infection
Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia...
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6344202 |
DNA immunization against chlaymdia infection
Nucleic acid, including DNA, for immunization to generate a protective immune response in a host, including humans, to a major outer membrane protein of a strain of Chlamydia, preferably contains a...
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6340463 |
Identification of antigenic peptide sequences
Identification of linear amino acid antigenic sequences for the production of both polyclonal and monoclonal antibodies to defined antigenic domains is described. Also described are antigenic...
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6307022 |
Def
The invention provides def polypeptides and DNA (RNA) encoding def polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing def...
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6277965 |
CysS
The invention provides cysS polypeptides and DNA (RNA) encoding cysS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing cysS...
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6251398 |
Materials and methods for intracellular transport and their uses
Coupled polypeptides and fusion polypeptides for intracellular transport, and their preparation and use, include (i) an aminoacid sequence with the transport function of herpesviral VP22 protein...
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6248563 |
Chlamydia trachomatis serotype D genes
A plasmid isolated from Clamydia trachomatis is described, which comprises 8 genes encoding proteins useful in the formulation of vaccines or diagnostic test for determining the bacterium or...
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6248562 |
Chimeric proteins comprising borrelia polypeptides and uses therefor
Chimeric nucleic acids encoding chimeric Borrelia proteins consisting of at least two antigenic polypeptides from corresponding and/or non-corresponding proteins from the same and/or different...
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6228364 |
GidA1
The invention provides gidA1 polypeptides and DNA (RNA) encoding gidA1 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing...
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6207647 |
RatA
The invention provides ratA polypeptides and DNA (RNA) encoding ratA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ratA...
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6165478 |
DNA encoding Chlamydia pneumoniae antigenic polypeptide
Chlamydia pneumoniae antigenic polypeptides, which comprise polypeptide A containing a sequence of at least 5 consecutive amino acids in the polypeptide of SEQ ID NO: 1; DNAs encoding said...
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6146839 |
Chlamydia pneumoniae antigens, method for production of the antigens, method and reagents for measurement of anti-Chlamydia pneumoniae antibodies using the antigens
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6110705 |
Recombinant Chlamydia trachomatis pgp3 fusion protein
A plasmid isolated from Chlamydia trachomatis is described, which comprises 8 genes encoding proteins useful in the formation of vaccines or diagnostic test for determining the bacterium or...
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6004563 |
Feline vaccine compositions and method for preventing chlamydia infections or diseases using the same
This invention provides a feline vaccine composition comprising an immunogenically active component having inactivated mammalian chlamydial cells or antigens derived there-from, in combination with...
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6001372 |
Antigenic peptides of Chlamydia trachomatis
Disclosed herein are short antigenic peptides of MOMP protein from Chlamydia trachomatis. They can be used to stimulate antigenic responses and to diagnose the presence of the bacteria.
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5989884 |
HisS polypeptides from Chlamydia trachomatis
The invention provides hisS polypeptides and DNA (RNA) encoding hisS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing hisS...
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5989553 |
Expression library immunization
A general method for vaccinating against any pathogen is presented. The method utilizes expression library immunization, where an animal is inoculated with an expression library constructed from...
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5972350 |
Feline vaccines containing Chlamydia psittaci and method for making the same
The present invention relates to feline vaccines comprising inactivated a non reactive Chlamydia psittaci for prevention and treatment of chlamydia diseases in cats.
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5900418 |
Method for treatment of obesity
A method is provided for the control of obesity comprising administering to a mammal including humans suffering from obesity an acetylcholine esterase reactivator or prodrug derivative thereof...
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5840297 |
Vaccine comprising anti-idiotypic antibody to chlamydia GLXA and process
A genus specific chlamydia vaccine is provided which comprises an anti-idiotype antibody capable of producing in an animal an anti-anti-idiotypic antibody which recognizes a glycoplipid exoantigen...
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5780041 |
39-kilodalton antigen specific to Borrelia burgdorferi
The present invention relates to antigenic proteins specific to Borrelia burgdorferi which have a molecular weight of 28 kDa or 39 kDa as determined by SDS-PAGE and are reactivity with Lyme...
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5725863 |
Polypeptides useful in prevention of chlamydia infection
The present invention relates to a polypeptide vaccine and method to immunize subjects against Chlamydia. In particular, this invention relates to essentially pure polypeptides of Chlamydia...
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5716793 |
Method for diagnosing a patient for chlamydia
A method of detecting chlamydia in a extracellular sample is provided which comprises contacting the sample with an idiotypic antibody to GLXA to form an immunocomplex and detecting the immunocomplex.
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5656275 |
Recombinant raccoon pox virus comprising the DNA encoding the nucleocapsid protein of feline infectious peritonitis virus
This invention provides a recombinant raccoon poxvirus that expresses the nucleocapsid and transmembrane proteins of Feline Infectious Peritionitis Virus. The recombinant viruses are useful as...
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5656271 |
Oral vaccine comprising anti-idiotypic antibody to chlamydia glycolipid exoantigen and process
A genus specific chlamydia oral or injectable vaccine is provided which comprises an anti-idiotype antibody capable of producing in an animal an anti-idiotypic antibody or Fab fragment thereof...
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4386065 |
Vaccine against EAE
A vaccine composition and method for the immunization of ewes against EAE (enzootic abortion in ewes) based upon inactivated Chlamydia sp. propagated in cell culture. The invention also relates to...
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4328208 |
Vaccine against chlamydous infections of farm animals
The vaccine against chlamydous infections consists of an inactivated suspension of cells of yolk sacks of chicken embryos infected with a chlamydous infectant in a physiological solution or a...
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