Matches 151 - 200 out of 224 < 1 2 3 4 5 >
Match Document Document Title
6221353 Antibodies Which Bind Mycobacterial Tuberculosis Proteins  
Antibodies that bind Mycobacterium tuberculosis 28 kDa proteins and immune complexes between the antibodies and proteins.
6210684 Method for delaying the onset of AIDS  
Antigenic and/or immunoregulatory material derived from Mycobacterium vaccae is useful for delaying the onset of AIDS with or without associated tuberculosis.
6177086 DNA molecule conferring on Mycobacterium tuberculosis resistance against antimicrobial reactive oxygen and nitrogen intermediates  
The present invention relates to a DNA molecule conferring on Mycobacterium tuberculosis resistance to antimicrobial reactive oxygen intermediates and reactive nitrogen intermediates. The protein...
6160093 Compounds and methods for treatment and diagnosis of mycobacterial infections  
The present invention provides polypeptides comprising an immunogenic portion of a M. vaccae protein and DNA molecules encoding such polypeptides, together with methods for their use in the...
6156322 Polynucleotides and polypeptides in pathogenic mycobacteria and their use as diagnostics, vaccines and targets for chemotherapy  
The invention provides a nucleotide sequence representing a pathogenicity island found in species of pathogenic mycobacteria. The islands are shown as SEQ ID NOs: 3 and 4 and comprises several open...
6139844 Method for treating or eliminating a parasitic disease  
A method for treating or eliminating a protozoal or parasitic disease in an animal in which a sufficient amount of a bacterial cell wall extract is administered to the animal having the protozoal...
6120776 Diagnostic skin test for tuberculosis  
Diagnostic methods capable of discriminating between cell mediated immunologic responses due to on the one hand active tuberculosis caused by bacteria belonging to the tuberculosis complex...
6110469 Hybrid plasmid for 38 kDa antigen of M. tuberculosis  
The invention concerns a hybrid plasmid for the expression of unfused 38 kDa antigen of M. tuberculosis in E. coli, E. coli with the plasmid, an 38 kDa antigen and a protein of about 33 kDa useful...
6060259 Mycobacterium proteins and applications  
Mycobacterium proteins, in particular those of M. bovis, having molecular weights between approximately 44.5 and 47.5 kD. These proteins can have molecular weights of approximately 45 kD or 47 kD...
6056964 Immunotherapeutic agent and its use  
A method for delaying or preventing the growth or spread of a malignant neoplasm by administering to a subject in need material which comprises killed cells of Mycobacterium vaccae in an amount...
6054133 Anti-microbial targeting for intracellular pathogens  
A method and composition are provided for treating intracellular pathogens that reside in phagosomes. The compositions include antibiotics which are conjugated with transferrin or other ligands to...
6004771 Method for processing mycrobacteria  
A method for the preparation of Mycobacteria from any liquid, semi solid or exotic source is described. The extracted Mycobacterial sample is suitable for detection by culture and amplification.
6001361 Mycobacterium vaccae antigens  
The present invention provides polypeptides comprising an immunogenic portion of a M. vaccae soluble protein and DNA molecules encoding such polypeptides, together with methods for their use in the...
5989553 Expression library immunization  
A general method for vaccinating against any pathogen is presented. The method utilizes expression library immunization, where an animal is inoculated with an expression library constructed from...
5976543 12-kDa protein derived from M. Tuberculosis useful for treatment of autoimmune diseases  
Disclosed is a 12-kDa PPD protein isolated and purified from the purified protein derivative, the major fraction of Mycobacterium tuberculosis that protects mice against the induction of...
5955077 Tuberculosis vaccine  
The invention relates to novel secreted antigens from mycobacteria capable of evoking early (within 4 days) immunological responses from T-helper cells in the form of gamma-interferon release in...
5885580 Anti-AIDS secretory recombinant BCG vaccine  
A vaccine containing Mycobacterium bovis BCG which secretes a fusion protein to be obtained by inserting a foreign antigen peptide into the molecular surface of a secretory protein, a carrier,...
5885588 Mycobacterium vaccae for treatment of long term autoimmune conditions  
Antigenic and/or immunoregulatry material derived from Mycobacterium vaccae is useful in the treatment of mental diseases associated with an autoimmune reaction initiated by an infection and/or the...
5882654 Polyvalent melanoma vaccine  
A new polyvalent melanoma cell vaccine is disclosed comprised of one or more allogeneic melanoma cell lines which contain effective concentrations of melanoma associated antigens. Further disclosed...
5858369 Anti-acids secretory recombinant BCG vaccine  
A vaccine containing Mycobacterium bovis BCG which secretes a fusion protein to be obtained by inserting a foreign antigen peptide into the molecular surface of a secretory protein, a carrier,...
5853737 Method for inducing a CD1-restricted immune response  
The present invention is based on the observation that CD1 functions to present foreign and autoimmune antigens to a select subpopulation of T-cells. Based on this observation, the present...
5840855 Mycobacterial recombinants and peptides  
Recombinant 540 amino acid residue and 517 amino acid residue proteins encoded by the genome of Mycobacterium tuberculosis are disclosed as are vectors for propagating their DNA sequences and...
5833996 Treatment of psoriasis using dead cells of Mycobacterium vaccae  
Immunoregulatory material derived from Mycobacterium vaccae, especially dead cells of M. vaccae, are useful for the treatment of pathological conditions (other than mycobacterial disease and...
5830475 Recombinant mycobacterial vaccines  
The present invention relates to recombinant mycobacteria, particularly recombinant M. bovis BCG, which express heterologous DNA encoding a product (protein or polypeptide) of interest, such a...
5783386 Mycobacteria virulence factors and a novel method for their identification  
Polynucleotides associated with virulence in mycobacteria, and particularly a fragment of DNA isolated from M. bovis that contains a region encoding a putative sigma factor. Also provided are...
5780034 Diagnosis and treatment of insulin dependent diabetes mellitus using heat shock protein determinents  
A 65 KD heat shock protein, proteins cross-reactive therewith, antibodies thereto or T cells specific thereto can be used for detecting in humans the existence of, a tendency to develop, or the...
5776465 Recombinant mycobacterial vaccines  
The present invention relates to recombinant mycobacteria, particularly recombinant M. bovis BCG, which express heterologous DNA encoding a product (protein or polypeptide) of interest, such a...
5759992 Immunotherapeutic agent derived from bacteria and method for its manufacture  
An immunotherapeutic agent is prepared from cells of E. coli or members of the genus Mycobacterium. The material is effective as an anti-tumor agent, an immunostimulant, and an adjuvant. Also...
5759554 Immunostimulatory bacterial cell wall traction  
The present invention relates to an immunotherapeutic agent that is effective in treating a variety of diseases in animals and humans. More particularly, the present invention is a preparation of a...
5731151 Regulator of contact-mediated hemolysin  
The present invention relates to a nucleic acid that encodes a hemolysin protein and to a nucleic acid that encodes a positive regulator of hemolysis. The nucleic acid can be the basis of a vaccine...
5714593 DNA from mycobacterium tuberculosis which codes for a 45/47 kilodalton protein  
Mycobacterium tuberculosis protein having a molecular weight of 28 779 Da, and hybrid proteins containing at least portions of its sequence. These proteins may in particular be used in vaccines or...
5712123 Mixture having antitumor activities  
A purified hot-water extract from Mycobacterium bovis (BCG vaccine) has been found to have significant antitumor activity against a mouse bladder tumor model and a murine sarcoma in vivo, but not...
5679347 Methods of isolating CD1-presented antigens, vaccines comprising CD1-presented antigens, and cell lines for use in said methods  
The present invention is based on the observation that CD1 functions to present foreign and autoimmune antigens to a select subpopulation of T-cells. Based on this observation, the present...
5658749 Method for processing mycobacteria  
A method for the preparation of Mycobacteria from any liquid, semi-solid or exotic source is described. The extracted Mycobacterial sample is suitable for detection by culture and amplification.
5632995 Method for stimulation of reproductive performance  
The present invention relates to an immunostimulant composition and method of use that is effective for increasing reproductive performance in an animal or human. More particularly, the present...
5618916 Purified protein which functions as a mycobacterial receptor for fibronectin  
A method for the treatment of superficial urinary tract tumors in a mammal involves administering a diagnostically effective amount of a liposomal composition comprising a liposome, a...
5612182 Mycobacteriophage specific for the mycobacterium tuberculosis complex  
Mycobacteriophage DS6A has been characterized and found to specifically infect all species of the TB complex, without any detectable infection of mycobacteria species other than those of the TB...
5599541 Peptide sequence capable of inducing a delayed-type hypersensitivity reaction in the presence of living bacteria of the Mycobacterium tuberculosis complex and its applications  
Peptide sequence capable of initiating delayed hypersensitivity reactions of different intensity in the presence of living bacteria as opposed to dead bacteria of the Mycobacterium tuberculosis...
5599545 Mycobacterium as adjuvant for antigens  
Immunoregulatry material from a mycobacterium other an M. tuberculosis, especially killed cells of M. vaccae, is an advantageous adjuvant for administration with antigens (including allergens).
5527770 Immunotherapeutic agent derived from bacteria  
An immunotherapeutic agent is prepared from cells of E. coli or members of the genus Mycobacterium. The material is effective as an anti-tumor agent, an immunostimulant, and an adjuvant. Also...
5268170 Methods of treatment and diagnosis of autoimmune diseases, especially arthritic conditions  
A Mycobacterium bovis BCG polypeptide having a molecular mass of about 64 kD was found to be useful as an immunogen inducing resistance to autoimmune arthritis and similar autoimmune diseases. The...
5254459 Nucleotide and amino acid sequences of protein MTP40 of M. tuberculosis and synthetic peptides derived therefrom  
The present invention relates to novel chemically synthesized nucleotides and novel chemically synthesized peptides which have been found to be effective in assaying for the presence of M....
5108745 Tuberculosis and legionellosis vaccines and methods for their production  
Vaccines and methods for their use in producing effective immune responses in mammalian hosts subsequently exposed to infection by intracellular pathogens including Legionella pneumophila wherein...
5100663 Tyr-Gly compositions useful in increasing immune response  
Compositions for delaying the progression from AIDS to ARC, and for alleviating symptoms of AIDS and ARC are disclosed together with clinical results of use of such compositions in clinical trials...
5091308 Process for the enzymatic dispersal of Mycobacterium bovis - BCG  
Mycobacterium bovis BCG suspensions are treated with a protease enzyme such as pronase, resulting in the production of suspensions having smaller aggregates and single cells. Such suspensions, when...
4965192 A60-antigen from Mycobacteria and use thereof as tuberculin and as vaccine  
An interspecific antigen of Mycobacteria consists essentially of a mixture in substantially immunochemically pure form of a protein having a molecular weight of at least about 4×10 6 Daltons and...
4726947 Bacterial cell extract, process for preparing same, antitumor preparation containing same, and adjuvant preparation containing same  
Cells of a microorganism, such as Mycobacterium tuberculosis, belonging to the genus Mycobacterium are disrupted in distilled water or a suitable buffer solution, and then centrifuged or filtrated...
4724144 Immuno-therapeutic composition of killed cells from mycobacterium vaccae  
"Immuno-therapeutic agents of killed cells prepared from Mycobacterium Vaccae that are useful in the treatment of mycobacterial disease, especially tuberculosis or leprosy, in particular as an...
4716038 Methods for the alleviation or treatment of arthritic disease  
The invention provides pharmaceutical compositions for the alleviation of arthritic diseases. These contain as active ingredient mycobacteria or fractions of these, e.g. obtained by fractionation...
4699898 Tripeptides affecting immune response  
A tripeptide and derivatives thereof are described that amplify mammalian immune response. A purification process, methods of using, and pharmaceutical compositions for using the product are...
Matches 151 - 200 out of 224 < 1 2 3 4 5 >