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8895015 Norovirus capsid and rotavirus VP6 protein for use as combined vaccine  
The present invention relates to a combined norovirus and rotavirus vaccine for prevention of norovirus and rotavirus infection and/or viral-induced diarrheal and vomiting diseases in man. More...
8846057 Recombinant live attenuated foot-and-mouth disease (FMD) vaccine containing mutations in the L protein coding region  
Previously we have identified a conserved domain (SAP, for SAF-A/B, Acinus, and PIAS) in the foot-and-mouth disease virus (FMDV) leader (L) protein coding region that is required for proper...
8765141 Development of a marker foot and mouth disease virus vaccine candidate that is attenuated in the natural host  
We have generated novel molecularly marked FMDV A24LL3DYR and A24LL3BPVKV3DYR vaccine candidates. The mutant viruses contain a deletion of the leader coding region (LL) rendering the virus...
8722036 Methods for treating malignancies using coxsackieviruses  
There is a disclosed a method of killing abnormal cells such as malignant cells including melanoma cells, using a virus recognising at least one of a cell adhesion molecule and a complement...
8685412 Hemorrhagic feline calicivirus, calicivirus vaccine and method for preventing development of calicivirus disease  
The present invention relates to a novel, isolated and purified hemorrhagic feline calicivirus FCV-DD1. The invention further embraces monovalent and multivalent vaccines containing the new...
8663951 Method of producing virus-like particles of picornavirus using a small-ubiquitin-related fusion protein expression system  
A method for producing picornaviral capsid protein complexes (e.g., picornavirus like particles) in E. coli using a small-ubiquitin-related fusion protein expression system and an E. coli strain...
8551495 Anti-FMD vaccine composition and preparation and use thereof  
The present invention pertains to the field of immunology and genetic engineering. In particular, the present invention relates to the construction, preparation and use of a recombinant vaccine...
8486421 Antigen-norovirus P-domain monomers and dimers, antigen-norovirus P-particle molecules, and methods for their making and use  
A substituted Norovirus capsid protein monomer, having only the P-domain and called an antigen-Norovirus P-domain monomer, includes a foreign antigen inserted into one or more of three surface...
8481693 Virus like particle purification  
Methods for purifying human Calciviruses are disclosed, including Noroviruses and Sapoviruses.
8409587 Immunogenic composition  
The present invention relates to immunogenic compositions comprising a dried solid or highly viscous liquid formulation of inactivated polio virus (IPV) and a stabilizing agent wherein the IPV...
8357792 SRSV detection kit  
A polynucleotide base sequence represented by SEQ ID NO: 22, a vector containing the polynucleotide and a method of preparing a small round structure virus (SRSV) virus-like particle in insect...
8323663 Adenoviral vector-based foot-and-mouth disease vaccine  
The invention is directed to an adenoviral vector comprising at least one nucleic acid sequence encoding an aphthovirus antigen and/or a cytokine operably linked to a promoter. The adenoviral...
8277819 Norovirus particle for use as an antiviral or vaccine  
Norovirus capsid protein monomers having only the P domain, and not the hinge or S domain, can assemble spontaneously into an icosahedral form herein called the P-particle. Factors affecting the...
8236298 Methods and compositions for treatment of hematologic cancers  
The present invention relates to oncolytic Picornaviruses and methods and compositions for treating subjects having hematologic cancers. These include methods and compositions for treatment of...
8231879 Treatment of diseases caused by viral infection  
A method of prophylactic and/or therapeutic treatment of a mammal for a disease that is caused by a Ljungan virus infection, such as Myocarditis, Cardiomyopathia, Guillain Barre Syndrome, and...
8183220 Double-effective vaccine vector against foot-and-mouth disease virus (FMDV), methods of preparing and using the same  
A double-effective vaccine vector against foot-and-mouth disease virus having a bicistronic expression vector sequence, the bicistronic expression vector sequence is an antisense gene sequence...
8142793 Norovirus and Sapovirus antigens  
Immunogenic compositions that elicit immune responses against Norovirus and Sapovirus antigens are described. In particular, the invention relates to polynucleotides encoding one or more capsid...
8124104 Norovirus and sapovirus antigens  
Immunogenic compositions that elicit immune responses against Norovirus and Sapovirus antigens are described. In particular, the invention relates to polynucleotides encoding one or more capsid...
8119145 Methods for producing norovirus VLPS  
Immunogenic compositions that elicit immune responses against Norovirus and Sapovirus antigens are described. In particular, the invention relates to polynucleotides encoding one or more capsid...
8114416 Modified oncolytic viruses  
An isolated selected Picornavirus capable of lytically infecting or killing a cell substantially in the absence of intercellular adhesion molecule-1 (ICAM-1).
8101189 Vaccines and immunopotentiating compositions and methods for making and using them  
An immunopotentiating composition comprising a papaya mosaic virus (PapMV), or a virus-like particle (VLP) derived from PapMV coat protein, which is capable of functioning as an adjuvant and thus...
7977098 Antigenic binding patterns of norovirus to human histo-blood group antigens  
The invention provides a compound which competitively inhibits the binding of a norovirus with a native blood antigen of a human host, as well as a kit for determining whether an individual has...
7879338 Vectors and methods for immunization against norovirus using transgenic plants  
The present invention relates to a synthetic plant-optimized nucleic acid molecule having a Norwalk virus capsid protein coding nucleotide sequence, and nucleic acid constructs, host cells,...
7850978 Vaccine against feline calicivirus  
The present invention relates to improved methods and immunogenic and/or vaccine compositions for providing an immune response to feline calicivirus, including hypervirulent strains of feline...
7833533 Enhanced antiviral activity against foot and mouth disease  
Previously, we showed that type I interferon (alpha/beta interferon [IFN-α/β]) can inhibit foot-and-mouth disease virus (FMDV) replication in cell culture, and swine inoculated with 109 PFU of...
7815913 Chimeric tymovirus-like particles and process thereof  
The present disclosure relates to chimeric tymovirus-like particles (TVLPs) comprising a fusion protein that further comprises of a first protein that is a truncated tymovirus coat protein and a...
7807169 Stratified and cryogenically stored vaccines, process for their preparation  
A composition comprising at least one antigenic medium and at least one adjuvant, wherein the at least one antigenic medium and the at least one adjuvant each comprise one or more phases which are...
7790876 Sequences diagnostic for foot and mouth disease  
Methods and materials for the detection of the foot and mouth disease virus (FMDV). The methods may utilize PCR amplification, with or without an internal positive control, and appropriate primer...
7790169 Methods of vaccine administration, new feline caliciviruses, and treatments for immunizing animals against feline paraovirus and feline herpes virus  
The present invention relates to a vaccine for immunizing a cat against feline viruses. The present invention also relates to a nucleic acid clone that encodes the capsid protein of the isolated...
7763260 Murine calicivirus  
The invention disclosed herein relates to a newly discovered murine norovirus, and compositions and methods related thereto.
7691627 Nucleic acid sequences encoding D1 and D1/D2 domains of human coxsackievirus and adenovirus receptor (CAR)  
The invention provides recombinant human CAR (coxsackievirus and adenovirus receptor) polypeptides which bind adenovirus. Specifically, polypeptides corresponding to adenovirus binding domain D1...
7674469 Feline influenza vaccine and method of use  
This invention is directed to a vaccine and a method for using the vaccine to protect a feline from influenza virus infection. The vaccine comprises one or more antigens from one or more H3, N8,...
7611719 Enterovirus, vaccines, medicaments and diagnostic kits  
The invention provides a new enteroviral species call EV79, and functional parts, derivatives and analogues of said virus. Proteinaceous molecules capable of specifically binding EV79, such as...
7575753 SRSV detection kit  
This invention relates to an SRSV detection kit comprising all antibodies against SRSV-related virus constituting peptides selected from the following peptide groups (a) to (k), respectively: (a)...
7531182 Vaccine against foot-and-mouth disease  
A vaccine against foot-and-mouth disease, using as antigen an efficient amount of empty capsids of the foot-and-mouth virus. The empty capsids are obtained by expressing, in eukaryotic cells, cDNA...
7527801 Norovirus and Sapovirus antigens  
Immunogenic compositions that elicit immune responses against Norovirus and Sapovirus antigens are described. In particular, the invention relates to polynucleotides encoding one or more capsid...
7455972 PCR-based method of detecting murine calicivirus  
The invention disclosed herein relates to a newly discovered murine norovirus, and compositions and methods related thereto.
7442380 Treatment of diseases caused by viral infection  
A method of prophylactic and/or therapeutic treatment of a mammal for a disease that is caused by a Ljungan virus infection, such as Myocarditis, Cardiomyopathia, Guillain Barré Syndrome, and...
7309495 Hemorrhagic feline calicivirus  
The present invention relates to a vaccine for immunization against a viral infection caused by a hemorrhagic feline calicivirus (hFCV), a novel, a typical and unusually virulent form of a...
7306807 Hemorrhagic feline calicivirus, calicivirus vaccine and method for preventing calicivirus infection or disease  
The present invention relates to a novel, isolated and purified hemorrhagic feline calicivirus FCV-DD1. The invention further embraces monovalent and multivalent vaccines containing the new...
7264816 Virulent systemic feline calicivirus  
The present invention relates to a vaccine for immunization against a viral infection caused by a virulent systemic feline calicivirus (VS-FCV), a novel, atypical and unusually virulent form of a...
7189401 Live attenuated viruses for use as vectors or vaccines  
The present invention provides modified viral genomes for use as vaccines or vectors, which are improved in their ability to retain attenuating mutations. The genomes are from viruses that...
7122193 Retro peptides, antibodies thereto and their uses for vaccination and in vitro diagnosis  
The present invention relates to retro peptides, as well as antibodies thereto, and to their uses, chiefly in the field of preparation of pharmaceutical compositions, in particular vaccines, and...
7101554 Picornaviruses, vaccines and diagnostic kits  
A new group of picornaviruses is disclosed. The picornaviruses of the invention comprise in the non-coding region of their viral genome a nucleotide sequence which corresponds to cDNA sequence (I)...
7090855 Prevention of Type 1 diabetes and other non-polio enterovirus diseases  
Live virus vaccines comprise attenuated viruses, while other vaccines comprise killed viruses or parts thereof. It has now been found that the immune response induced by oral poliovirus vaccine...
7041444 Murine calicivirus  
The invention disclosed herein relates to a newly discovered murine norovirus, and compositions and methods related thereto.
7037506 Vaccine accelerator factor (VAF) for improvement of vaccinations in poultry  
The present invention provides a vaccine accelerator factor (VAF) which is an in ovo nucleotide immuno-stimulant. The VAF contains one or more DNA constructs, each having a DNA molecule and a...
7029682 Inactivated vaccine against feline calicivirosis  
Immunogenic preparations and vaccines, in particular which are inactivated, effective against feline calicivirosis, based on an FCV virus strain 431 as deposited at the CNCM under the accession...
6984387 Immunogenic peptides of foot-and-mouth disease viruses  
The present invention relates to FMDC vaccine based on peptides having a sequence of at least 8 amino acids, which corresponds to a partial sequence of the non-structural protein region of FMDV,...
6982088 Vaccine composition and stabilization method using high molecular weight PVP  
The invention concerns the stabilization of a vaccine composition maintained in liquid state by the use of high molecular weight polyvinylpyrrolidone, hence eliminating the use of albumen. The...

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