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7622124 |
Mycoplasma hyopneumoniae bacterin vaccine
The invention provides an improved Mycoplasma hyopneumoniae bacterin vaccine composition, which advantageously provides immunity from infection after a single administration. The composition...
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7595058 |
Chlamydia antigens and vaccine uses of the protein
The present invention provides vaccines and methods for immunizing a host, including humans, against disease caused by infection by a strain of Chlamydia, specifically C. pneumoniae. The...
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7576066 |
Nucleic acid compositions for stimulating immune responses
The invention provides an immunostimulatory nucleic acid comprising CpG motifs, and methods of use thereof in stimulating immunity.
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7569553 |
Nucleic acid compositions for stimulating immune responses
The invention provides an immunostimulatory nucleic acid comprising CpG motifs, and methods of use thereof in stimulating immunity.
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7569383 |
Chimeric flavivirus vectors
The invention provides chimeric flavivirus vectors including foreign peptides inserted into the envelope proteins of the vectors and methods of using these vectors.
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7563449 |
Methods for reducing cattle reproductive diseases
The present invention relates to methods for treating or preventing diseases or disorders in a pregnant cow and calf nursing a pregnant cow caused by infection by Bovine Viral Diarrhea Virus (BVDV)...
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7544361 |
Hetero type pentamer recombinant vaccine
A heteropentamer composed of a fusion monomer ( 32 ) comprising a fusion protein of an antigenic amino acid sequence and an amino acid sequence of a monomer of a mucous membrane-binding protein and...
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7521060 |
Pathogen for bacterial poultry disease
The invention belongs to the field of animal health and in particular the causative agent of a new bacterial poultry disease, Gallibacterium . The invention provides said Gallibacterium ...
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7501128 |
IHNV G protein for immune stimulation
A vaccine comprises a portion of IHNV G protein and a portion of a second protein from a fish pathogen, or their respective nucleic acid coding sequences. The presence of the IHNV G protein boosts...
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7455843 |
Adjuvant activities of mutants of LT-IIa and LT-IIb enterotoxin lacking binding to ganglioside
The present invention describes the adjuvant activity of mutants of LT-IIa and LT-IIb enterotoxin which lack ganglioside binding activity. The adjuvant activity of the LT-IIb(T13I) mutant is...
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7431930 |
Infectious bursal disease virus (IBDV) mutant expressing virus neutralising epitopes specific for classic-and variant IBDV strains
The present invention provides a classic IBDV mutant that additionally comprises virus neutralising epitopes 67 (specific for variant-E IBDV).
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7410954 |
Adenovirus serotype 30 (Ad30)
The present invention provides an adenovirus serotype 30 (Ad30) fiber amino acid sequence. The present invention also provides polynucleotides and expression vectors encoding an Ad30 fiber and...
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7404960 |
Multivalent vaccine composition having increased stability of capsular polysaccharide
A vaccine composition comprising two valences is provided: (i) a first valence which is adjuvant-enhanced with aluminum hydroxide and (ii) a second valence which contains a polysaccharide of...
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7384640 |
Mutant cholera holotoxin as an adjuvant
A mutant cholera holotoxin featuring a point mutation at amino acid 29 of the A subunit, wherein the glutamic acid residue is replaced by an amino acid other than aspartic acid, is useful as an...
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7309493 |
Inactivated bovine scours vaccines, process and method of preventing bovine scours
Inactivated scours vaccines for immunization and protection of bovine animals from disease caused by infection with bovine rotavirus and bovine coronavirus, which comprise and effective amount of...
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7235243 |
Immunological combination compositions and methods
Immununological compositions and methods for making and using them. The compositions contain at least one antigen and at least one lipoprotein and optionally an adjuvant. The lipoprotein can itself...
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7169394 |
Mycoplasma hyopneumoniae bacterin vaccine
The invention provides an improved Mycoplasma hyopneumoniae bacterin vaccine composition, which advantageously provides immunity from infection after a single administration. The composition...
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7157089 |
Immune responses using compositions containing stress proteins
The present invention relates to a vaccine for inducing an immune response to an antigen in a vertebrate (e.g., mammal) comprising an antigen and all or a portion of a stress protein or all or a...
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7122191 |
Microfluidized oil-in-water emulsions and vaccine compositions
This invention provides submicron oil-in-water emulsions useful as a vaccine adjuvant for enhancing the immunogenicity of antigens. The present invention also provides vaccine compositions...
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7105574 |
Adjuvant compositions and methods for enhancing immune responses to polynucleotide-based vaccines
The invention provides adjuvants, immunogenic compositions, and methods useful for polynucleotide-based vaccination and immune response. In particular, the invention provides an adjuvant of...
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7101555 |
Mycobacterial proteins, microorganisms producing them and their use for vaccines and the detection of tuberculosis
Mycobacterium tuberculosis protein having a molecular weight of 28 779 Da, and hybrid proteins containing at least portions of its sequence. These proteins may in particular be used in vaccines...
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7098303 |
Conserved motif of hepatitis C virus E2/NS1 region
Immunogenic polypeptides comprising hepatitis C virus (HCV) immunogens are described. The HCV immunogen comprises the amino acid sequence...
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7090854 |
Chicken anaemia viruses of low pathogenicity
The present invention provides a new antigenic type of chicken anaemia viruses (CAV). The CAV according to this invention is isolatable from turkeys in the field and its virulence for chickens is...
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7087236 |
Method for inducing a cell-mediated immune response and improved parenteral vaccine formulations thereof
A method of inducing either a T H 1 polarized immune response, a T H 2 polarized immune response or a combined T H 1 and T H 2 response to an antigen and associated vaccine formulations are...
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7087234 |
Recombinant multivalent viral vaccine
The present invention relates to multivalent recombinant raccoon poxviruses, containing more than one exogenous gene inserted into either the thymidine kinase gene, the hemagglutinin gene, or a...
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7052689 |
Method for producing therapeutically suitable glutaminase
DNA encoding a therapeutically suitable glutaminase has been molecularly cloned. This allows one to obtain a polypeptide which is a therapeutically suitable glutaminase free of contaminating...
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7018638 |
Mycoplasma hyopneumoniae bacterin vaccine
The invention provides an improved Mycoplasma hyopneumoniae bacterin vaccine composition, which advantageously provides immunity from infection after a single administration. The composition...
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7008790 |
Method and composition for an early vaccine to protect against both common infectious diseases and chronic immune mediated disorders or their sequelae
A method of immunization, and compositions therefor, are provided for substantially preventing or reducing the symptoms of at least one infectious disease and at least one chronic immune mediated...
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6974577 |
Inactivated bovine scours vaccines, processes and method of preventing bovine scours
Inactivated scours vaccines for immunization and protection of bovine animals from disease caused by infection with bovine rotavirus and bovine coronavirus, which comprise and effective amount of...
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6953581 |
Porcine circovirus and parvovirus vaccine
The invention relates to antigenic preparations and vaccines directed against the porcine multisystemic wasting syndrome (PMWS), comprising at least one porcine circovirus antigen, preferably type...
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6951649 |
Methods of making neuraminidase-supplemented compositions
The present invention relates to a method for formulating a vaccine composition which comprises an anti-influenza vaccine, wherein the improvement of the vaccine composition is that the vaccine...
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6946132 |
Vaccine compositions and methods useful in inducing immune protection against arthritogenic peptides involved in the pathogenesis of rheumatoid arthritis
Vaccine compositions useful in inducing immune protection in a host against arthritogenic peptides involved in the pathogenesis of rheumatoid arthritis are disclosed. Each vaccine composition...
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6936263 |
Th1 inducing natural adjuvant for heterologous antigens
The present invention relates to the use of the major OprI lipoprotein of Pseudomonas aeruginosa to elicit a Type-1 immune response towards a heterologous antigen. The invention relates...
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6893644 |
Hepatitis vaccines containing 3-O-deacylated monophoshoryl lipid A
A vaccine formulation for the treatment or prophylaxis of hepatitis, especially hepatitis, especially hepatitis B, infections is provided comprising the hepatitis antigen and a suitable carrier...
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6803035 |
Anti-diarrheal and method for using the same
A food product and method for treating and preventing diarrhea in a subject animal suffering from or susceptible to diarrhea. The method comprises administering an egg product to the subject animal...
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6793928 |
Vaccines with an LTB adjuvant
The present invention relates to a vaccine containing at least one particulate immunogen and an adjuvanting amount of B subunits of heat-labile enterotoxin characteristic of E. Coli . More in...
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6783765 |
Process for the preparation of a vaccine for the treatment of tuberculosis and other intracellular infections diseases and the vaccine produced by the process
The present invention relates to a process for the preparation of a vaccine against tuberculosis and other intracellular pathogens, this vaccine is targeted against intracellular pathogens, more...
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6780420 |
Carrier protein having an adjuvant effect, immunogenic complex containing it, process for their preparation, nucleotide sequence and vaccine
The invention relates to an adjuvant product which is intended to improve the activity of a molecule when administered to a host, characterized in that it comprises at least one part of the P40...
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6770275 |
Live attenuated RTC-producing bacteria of the family
The present invention relates to live attenuated RTX-toxin producing bacteria of the family Pasteurellaceae, of which the attenuation is due to the fact that they produce RTX toxin in a...
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6756040 |
Vaccine composition comprising a polysaccharide conjugate antigen adsorbed onto aluminum phosphate
The invention relates to a vaccine formulation for the prevention of Haemophilus Influenzae Type B (Hib) infections and where the antigen is adsorbed onto aluminum phosphate. The invention also...
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6743430 |
Multicomponent vaccine containing clostridial and non-clostridial organisms in a low dose
Disclosed herein is a multicomponent low dose vaccine comprising a safe and immunogenically effective combination of a protective antigen component or components of clostridial organism, a...
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6682746 |
Adjuvanted vaccine which is substantially free of non-host albumin
Disclosed herein is a serum-based adjuvanted vaccine which is substantially free of non-host albumin and the use thereof in reducing or preventing post-vaccination systemic reactions.
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6676945 |
Mycobacterial proteins, microorganisms producing them and their use for vaccines and for the detection of tuberculosis
Mycobacterium tuberculosis protein having a molecular weight of 28.779 Da, and hybrid proteins containing at least portions of its sequence. These proteins may in particular be used in vaccines...
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6645500 |
Method for down-regulating osteoprotegerin ligand activity
The invention provides a novel method for down-regulating the biological activity of osteoprotegerin ligand (OPGL, TRANCE) thereby rendering possible the treatment/amelioration of diseases...
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6632664 |
Avian infectious herpesvirus recombinants and recombinant vaccines prepared with the use of the same
An avian infectious recombinant herpesvirus is prepared by inserting a foreign gene, in particular a heterologous antigen gene, into an insertion site in an untranslated genetic region in the...
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6610307 |
Immunity against pasteurella haemolytica leukotoxin
Bovine respiratory disease (BRD) complex, shipping fever, or pneumomic pasteurellosis, is a multifactorial disease whereby a combination of viral infection, adverse environment and poor immune...
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6607725 |
Conjugate vaccine for nontypeable Haemophilus influenzae
A conjugate vaccine for Nontypeable Haemophilus influenzae comprising lipooligosaccharide from which esterified fatty acids have been removed conjugated to an immunogenic carrier. The vaccine is...
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6592870 |
Method and kit using recombinant proteins in fusion of porcine reproductive and respiratory syndrome virus and for diagnosis
The recombinant fusion proteins comprise the protein of the nucleocapsid of the porcine reproductive and respiratory syndrome virus (PRRSV) obtained both from a European isolate of PRRSV as well as...
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6585981 |
Temperature-sensitive live vaccine for Mycoplasma hyopneumoniae
The present invention provides a live temperature-sensitive vaccine for Mycoplasma hyopneumoniae . The present invention also provides methods of vaccinating a swine against colonization or...
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6576243 |
Polynucleotide vaccine formula against porcine reproductive and respiratory pathologies
Disclosed and claimed is: an immunogenic or vaccine composition for inducing in an avian host an immunological response against avian pathologies containing at least one plasmid that contains and...
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