|
Match
|
Document |
Document Title |
|
|
8173140 |
Compositions and methods for activating innate and allergic immunity
Methods for making and using therapeutic formulations of Proteosome-based immunoactive compositions are provided. The immunogenic compositions, which include Proteosomes and liposaccharides, may be...
|
|
|
8173135 |
Methods for preparing complex multivalent immunogenic conjugates
Methods for preparing complex multivalent immunogenic conjugates that include simultaneously reacting a plurality or immunogenic-distinct polysaccharides with at least one protein to make the...
|
|
|
8168195 |
Vaccines against Escherichia coli O157 infection
This invention relates to conjugates of the O-specific polysaccharide of E. coli O157 with a carrier, and compositions thereof, and to methods of using of using of these conjugates and/or...
|
|
|
8168203 |
Shigella protein antigens and methods
The present invention relates to protein antigens IcsP2 and SigA2 from Shigella that are common among numerous Shigella types and species and which can protect against shigellosis or other enteric...
|
|
|
8147847 |
Shigella protein antigens and methods
The present invention relates to protein antigens IcsP2 and SigA2 from Shigella that are common among numerous Shigella types and species and which can protect against shigellosis or other enteric...
|
|
|
8137675 |
Bont/a peptides and methodsof predicting and reducing immunoresistance to botulinum toxin therapy
The present invention provides BoNT/A peptides as well as methods of predicting or determining immunoresistance to botulinum toxin therapy in an individual using BoNT/A peptides.
|
|
|
8133492 |
Pneumococcus polysaccharide-related vaccines
This invention provides novel nitrocellulose-based or Hydrogel-based microarrays and methods of making and using them (1) to detect the presence of one or more agents in a sample, (2) to determine...
|
|
|
8128942 |
Anti-sepsis conjugate vaccine
The present invention provides an immunogenic conjugate comprising biologically deacylated gram-negative bacterial moieties linked to D. discoideum proteinase 1, as well as novel subunits thereof,...
|
|
|
8101192 |
Methods for producing an immune response to tuberculosis
Methods for producing an immune response to Mycobacterium tuberculosis (Mtb) are disclosed herein. In several examples, the immune response is a protective immune response. In additional...
|
|
|
8092812 |
Methods and compositions for immunization against chlamydial infection and disease
The present invention provides Chlamydia proteins and compositions and methods of use in the treatment/prevention of chlamydial infection in a subject, for eliciting an immune response in a subject...
|
|
|
8062641 |
Immunogens for meningitidis-A vaccines
An oligosaccharide useful for a Meningitidis A vaccine contains a first mannose unit having a spacer in the alpha configuration at C-1, which spacer is capable of conjugating to a protein, and...
|
|
|
8043624 |
Compositions and methods for treatment of microbial infections
The present invention relates to methods and compositions for treatment of microbial infections and for the enhancement of resistance to infection. The invention comprises administration of an...
|
|
|
8034351 |
Mucin fusion polypeptide vaccines, compositions and methods of use thereof
The present invention provides compositions and methods for augmenting vaccine immunogenicity using mucin-immunoglobulin fusion proteins.
|
|
|
8034348 |
Prevention and treatment of amyloidogenic disease
The invention provides improved agents and methods for treatment of diseases associated with amyloid deposits of Aβ in the brain of a patient. Such methods entail administering agents that induce ...
|
|
|
8034353 |
Peptide vaccine for inducing the production of anti-amyloid β-peptide antibody
An object of the present invention is to provide a peptide vaccine for preventing and/or treating diseases caused by amyloid β-peptide, such as Alzheimer's disease. The present invention solves ...
|
|
|
8029798 |
Multivalent vaccine composition with mixed carrier
The invention concerns a pharmaceutical composition for treating or preventing a certain number of infections caused by pathogenic agents such as bacteria, comprising as immunogen, one or several...
|
|
|
8017133 |
Multicomponent vaccines
Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or...
|
|
|
8007815 |
Combination meningitidis B/C vaccines
Combination vaccines for treating or preventing Neisseria meningitidis infection are described. The vaccines include Neisseria meningitidis serogroup B proteoliposomic vesicles and Neissera...
|
|
|
8007807 |
Multiple vaccination including serogroup C meningococcus
Various improvements to vaccines that include a serogroup C meningococcal conjugate antigen, including: (a) co-administration with acellular B. pertussis antigen; (b) co-administration with an...
|
|
|
8007817 |
Compositions and methods for treating microbial infections
The present invention relates to methods and compositions for treatment of microbial infections and for the enhancement of resistance to infection. The invention comprises administration of an...
|
|
|
8003112 |
Meningococcal and pneumococcal conjugate vaccine and method of using same
This disclosure relates to vaccine formulations comprising an immunogenic composition for inducing antibodies to both S. pneumoniae and N. meningitides in a subject. In a preferred aspect, the...
|
|
|
7998487 |
Antitoxin and vaccine platform based on nodavirus VLPs
Antitoxin and vaccine compositions based on nodavirus VLPs are provided. Anthrax antitoxin and vaccine compositions are provided. Methods of treating toxins with VLP-based antitoxins are provided....
|
|
|
7955605 |
Multivalent pneumococcal polysaccharide-protein conjugate composition
An immunogenic composition having 13 distinct polysaccharide-protein conjugates and optionally, an aluminum-based adjuvant, is described. Each conjugate contains a capsular polysaccharide prepared...
|
|
|
7939492 |
Factor C for treating gram-negative bacterial infection
Recombinant fragments of Factor C are disclosed. These proteins and peptides show great potency in recognizing, binding to, neutralizing and removing endotoxin. These molecules can thus be used for...
|
|
|
7914791 |
Vaccine
A method for stimulating the immune response to a vaccine applied to a mammalian subject includes the step of administering to the subject an effective amount of EtxB or a molecule having...
|
|
|
7892567 |
Methods and compositions for immunization against chlamydial infection and disease
The present invention provides Chlamydia proteins and compositions and methods of use in the treatment/prevention of chlamydial infection in a subject, for eliciting an immune response in a subject...
|
|
|
7883709 |
Stabilised compositions
This invention relates to the stabilization of a bacterial ADP-ribosylating exotoxin class protein (bARE), a method for analysing a bARE class protein, a method for the stabilization of the bARE...
|
|
|
7862823 |
Multivalent vaccine composition with mixed carrier
The invention concerns a pharmaceutical composition for treating or preventing a certain number of infections caused by pathogenic agents such as bacteria, comprising as immunogen, one or several...
|
|
|
7858101 |
Modified streptococcal polysaccharides and uses thereof
Modified streptococcal polysaccharides and methods of using the modified polysaccharides are provided herein.
|
|
|
7850973 |
Peptide conjugate compositions and methods for the prevention and treatment of alzheimer's disease
The invention provides compositions and methods for the treatment of diseases associated with amyloid deposits of Aβ in the brain of a patient, such as Alzheimer's disease. Such methods entail ...
|
|
|
7842299 |
Methods for producing an immune response to tuberculosis
Methods for producing an immune response to Mycobacterium tuberculosis (Mtb) are disclosed herein. In several examples, the immune response is a protective immune response. In additional...
|
|
|
7838018 |
Adjuvant combinations for immunization composition and vaccines
An adjuvant combination and a kit useful for immunization is provided. The kit contains an antigenic substance and an adjuvant combination of dimethyl dioctadecyl ammonium bromide (DDA-Br or...
|
|
|
7838003 |
BASB205 polypeptides and polynucleotides from Haemophilus influenzae
The invention provides BASB205 polypeptides and polynucleotides encoding BASB205 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic,...
|
|
|
7838014 |
Vaccine compositions comprising L2 and/or L3 immunotype lipooligosaccharides from LGTB- Neisseria meningitidis
The present invention relates to the field of neisserial vaccine compositions, their manufacture, and the use of such compositions in medicine. More particularly it relates to processes of making...
|
|
|
7824688 |
Glucan-based vaccines
Anti-glucan antibodies have been found to be protective against systemic fungal infection with C. albicans, but the protective efficacy can be inhibited by blocking antibodies. The invention...
|
|
|
7811591 |
Chimeric vaccine for haemophilus influenzae-induced disease
The invention described herein relates to a chimeric protein comprising the NTHi twitching pilus major subunit protein (PilA) presenting a portion of the NTHi OMP P5 protein. The invention provides...
|
|
|
7803386 |
Poly-gamma-glutamic conjugates for eliciting immune responses directed against bacilli
Immunogenic compositions and methods for eliciting an immune response against B. anthracis and other bacilli are provided that include immunogenic conjugates of a poly-γ-glutamic acid (γPGA) p...
|
|
|
7790172 |
Methods for reducing nasopharyngeal colonization of non-typable Haemophilus influenzae with synthetic chimeric fimbrin peptides
The present invention provides synthetic chimeric fimbrin peptides which induce an immunogenic response in animals to non-typable Haemophilus influenzae and that do not require tedious purification...
|
|
|
7754225 |
Method of protecting against staphylococcal infection
A method of preventing or treating staphylococcal bacterial infection in an individual is disclosed. A vaccine based on a conjugate of PS1 polysaccharide antigen can be used for active protection...
|
|
|
7749511 |
Anti-sepsis conjugate vaccine
The present invention provides an immunogenic conjugate comprising biologically deacylated gram-negative bacterial moieties linked to D. discoideum proteinase 1, as well as novel subunits thereof,...
|
|
|
7740853 |
Fcepsilon-pe chimeric protein for targeted treatment of allergy responses a method for its production and pharmaceutical compositions containing the same
The present invention generally relates to a new approach for the therapy of allergic responses, based on targeted elimination of cells expressing the FcεRI receptor by a chimeric cytotoxin ...
|
|
|
7709002 |
Mutated ras peptides for generation of CD8+Cytotoxic T lymphocytes
Mutant ras oncogene peptides may induce specific anti-ras cellular immune responses in vaccinated patients. Moreover, a human CD8+ CTL epitope(s) reflecting a specific point mutation in the K-ras...
|
|
|
7704506 |
Fcε-PE chimeric protein for targeted treatment of allergy responses a method for its production and pharmaceutical compositions containing the same
The present invention generally relates to a new approach for the therapy of allergic responses, based on targeted elimination of cells expressing the FcεRI receptor by a chimeric cytotoxin ...
|
|
|
7678379 |
Mycobacterium tuberculosis epitopes and methods of use thereof
The invention provides novel Class I HLA-A2 and Class II HLA-DR4-restricted epitopes and methods for their use in detecting T-cells in peripheral blood specific for infection or latency of...
|
|
|
7674469 |
Feline influenza vaccine and method of use
This invention is directed to a vaccine and a method for using the vaccine to protect a feline from influenza virus infection. The vaccine comprises one or more antigens from one or more H3, N8, H7...
|
|
|
7666438 |
Multicomponent vaccines
Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or...
|
|
|
7635480 |
Peptides for preventing, diagnosing and treating animal and/or human leptospirosis
The present invention provides a compound chosen from: a peptide represented by the sequence SEQ ID No: 1 below: SEQ ID No: 1...
|
|
|
7635483 |
Streptococcal C5a peptidase vaccine
Novel vaccines for use against β-hemolytic Streptococcus colonization or infection are disclosed. The vaccines contain an immunogenic amount of a variant of streptococcal C5a peptidase (SCP). Also ...
|
|
|
7628992 |
Modification of clostridial toxins for use as transport proteins
A chemical conjugate for treating a nerve cell related disorder is provided. This conjugate includes an active or inactive Clostridial toxin having specificity for a target nerve cell. The toxin is...
|
|
|
7598354 |
Campylobacter glycans and glycopeptides
Multiple strains and species of Campylobacter share a common glycan moiety which is present in a plurality of surface-exposed glycoproteins. This glycan has the formula: GalNAc-a1,...
|