Matches 201 - 250 out of 517 < 1 2 3 4 5 6 7 8 9 10 11 >
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6949345 Identification and cloning of a mycobacterial antigen corresponding to a heparin-binding haemagglutinin  
The present invention relates to peptide sequences enabling mycobacteria to adhere to host cells (e.g., epithelial cells). More particularly, the invention relates to a mycobacterial...
6936252 Streptococcus pneumoniae proteins and nucleic acid molecules  
Novel protein antigens from Streptococcus pneumoniae are disclosed, together with nucliec acid sequences encoding them. Their use in vaccines and in screening methods is also described.
6936259 CAMP factor of Streptococcus uberis  
The CAMP factor gene of Streptococcus uberis ( S. uberis ) is described, as well as the recombinant production of CAMP factor therefrom. Also disclosed are chimeric CAMP factor constructs,...
6923963 Diagnosis of ehrlichia canis and ehrlichia chaffeensis  
Diagnostic tools for for serodiagnosing ehrlichiosis in mammals, particularly in members of the Canidae family and in humans are provided. The diagnostic tools are a group of outer membrane...
6921536 Lawsonia intracellularis vaccine  
The present invention relates i.a. to nucleic acid sequences encoding novel Lawsonia intracellularis proteins. It furthermore relates to DNA fragments, recombinant DNA molecules and live...
6919080 Polypeptide for Haemophilus paragallinarum and process for preparing the same  
A novel peptide obtained from Haemophilus paragallinarum has been found useful for preventing avian infectious coryza. This polypeptide induces production of hemagglutination-inhibition antibody...
6913755 Mutants of Streptococcal toxin A and methods of use  
This invention is directed to mutant SPE-A toxins or fragments thereof, vaccine and pharmaceutical compositions, and methods of using the vaccine and pharmaceutical compositions. The preferred...
6913757 Live, avirulent strain of V. anguillarum that protects fish against infection by virulent V. anguillarum and method of making the same  
The present invention comprises the identification, characterization and sequencing of a gene within the V. anguillarum genome, the mugA gene, a live, attenuated strain of V. anguillarum which...
6913750 Therapeutic compounds structurally-linked to bacterial polypeptides  
A protein construct comprising a pilus protein portion, preferably a structurally stabilized pilus-protein, and an additional, or effector, portion other than a pilus protein or chaperone and...
6908619 Camp factor of streptococcus uberis  
The CAMP factor gene of Streptococcus uberis ( S. uberis ) is described, as well as the recombinant production of CAMP factor therefrom. CAMP factors can be used in vaccine compositions for the...
6908994 Collagen-binding proteins from enterococcal bacteria  
A collagen-binding MSCRAMM entitled Ace from enterococcal bacteria is provided which was homologous to the ligand-binding region of Cna, the collagen-binding MSCRAMM from Staphylococcus aureus ,...
6899881 H. PYLORI FLBA POLYPEPTIDES, IMMUNOGENIC AND VACCINATING COMPOSITIONS COMPRISING H. PYLORI FLBA POLYPEPTIDES, AND COMPOSITIONS FOR DETECTION OF AN INFECTION COMPRISING H. PYLORI FLBA POLYPEPTIDES  
The present application relates to nucleotide sequences which regulate the biosynthesis of the flagella proteins Helicobacter pylori , to the proteins encoded by these sequences and to a...
6899885 74-kilodalton outer membrane protein from Moraxella catarrhalis  
A protein from M. catarrhalis , designated the 74 kD protein, is isolated and purified. The 74 kD protein has an amino-terminal amino acid sequence which is conserved among various strains of M....
6887481 Bacterial-derived molecules and therapeutic and diagnostic uses therefor  
The present invention relates generally to molecules derived from a Mycobacterium species and recombinant, synthetic, derivative, homologue and analogue forms of said molecules. The molecules of...
6887482 Antigenic iron repressible proteins from N. meningitidis related to the hemolysin family of toxins  
An isolated, antigenic polypeptide comprises a segment having at least fifty amino acid residues. The amino acid sequence of the segment is present in N. meningitidis , and is different from, but...
6887480 Streptococcus pneumoniae proteins and vaccines  
The present invention relates to novel immunogenic polypeptides, and fragments thereof, and vaccines for the prevention and treatment of pneumococcal infection, especially by Streptococcus...
6872398 Conjugate vaccine against gram-negative bacterial infections  
The present invention relates to a broadly reactive vaccine against Gram-negative bacteria which is composed of a biological glycan-pilus conjugate. The conjugate core is a common pilus type to...
6872394 Non-toxic immune stimulating enterotoxin compositions  
Pyrogenic toxins, such as staphylococcal enterotoxins, modified in the disulfide loop region are provided. The modified toxins retain useful biological properties but have substantially reduced...
6872397 Method for treating neuromuscular disorders and conditions with botulinum toxin types A and B  
A method of treating a patient suffering from a disease, disorder or condition includes the administration to the patient of a therapeutically effective amount of botulinum toxin of a selected...
6861507 Screening of neisserial vaccine candidates and vaccines against pathogenic neisseria  
Methods of screening for vaccine candidates, vaccines against pathogenic neisscria and intermediaries for such vaccines have been developed. Two vaccine candidates TspA and TspB have been...
6855320 Fusion of non-hemolytic, truncated form of listeriolysin O to antigens to enhance immunogenicity  
Methods for enhancing the immunogenicity of an antigen via fusion to a non-hemolytic truncated form of listeriolysin O are provided.
6846487 Therapeutic compositions for treating infection by Lawsonia spp.  
The present invention relates generally to therapeutic compositions for the treatment and/or prophylaxis of intestinal disease conditions in animals and birds caused or exacerbated by Lawsonia...
6843999 Streptococcal ABC transporter protein  
A polypeptide suitable for use in vaccination against Streptococcal infections comprises: a) the amino acid sequence of SEQ ID No 1; b) a variant of (a) which is capable of binding an anti-MtsA...
6841358 RECOMBINANT PROTEINS OF FILAMENTOUS HAEMAGGLUTININ OF BORDETELLA, PARTICULARLY BORDETELLA PERTUSSIS, METHOD FOR PRODUCING SAME, AND USES THEREOF FOR PRODUCING FOREIGN PROTEINS OF VACCINATING ACTIVE PRINCIPLES  
A recombinant DNA containing a sequence (1) coding for a polypeptide heterologous to a filamentous haemagglutinin of Bordetella (Fha) fused within the reading frame to a sequence (2) located...
6835384 Nucleic acids and polypeptides specific of the neisseria genus pathogenic strains  
The invention concerns nucleic acids coding for polypeptides specific of the Neisseria genus pathogenic strains, the corresponding polypeptides, and their diagnostic and therapeutic applications.
6827936 Synthetic peptide vaccines for dental caries  
Vaccine compositions and immunogenic compositions are described which are glucosyltransferase subunit vaccines for dental caries and which contain at least one peptide which corresponds to a...
6822075 Protein L and hybrid proteins thereof  
The invention relates to sequences of protein L which bind to light chains of immunoglobulins. The invention also relates to hybrid proteins thereof which are able to bind to both light and heavy...
6811783 Immunogenic compositions for protection against chlamydial infection  
A protective immune response against Chlamydial infection is achieved by in vivo administration of an immunogenic composition comprising two vectors and a pharmaceutically-acceptable carrier...
6808711 Immunologically active proteins from Borrelia burgdorferi, nucleic acids which encode them, and their use in test kits and as vaccines  
The present invention relates to immunologically active proteins from Borrelia burgdorferi which are present in a form which is free of other proteins derived from Borrelia burgdorferi and...
6806253 Immunodulatory complex and use thereof in helicobacter diseases  
A therapeutical vaccine complex having activity specific for Helicobacter bacteria as well as non-specific immunomodulation activity for regulating the natural defenses of the body. The drug is...
6805868 Moraxella catarrhalis antigen, corresponding gene and uses thereof  
The invention provides BASB109 polypeptides and polynucleotides encoding BASB109 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic,...
6803043 Basbo27 proteins and genes from moraxella catarrhalis, antigens, antibodies, and uses  
The invention provides BASB027 polypeptides and polynucleotides encoding BASB027 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic,...
6800734 Leptospira vaccine antigens for the prevention of Leptospirosis  
Four antigenic preparations are provided, each of which contains a different protein from Leptospira which can be used immunologically in vaccines for leptospirosis caused by this organism. Also...
6797273 Neisseria meningitidis antigen  
The invention provides BASB053 polypeptides and polynucleotides encoding BASB053 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic,...
6790446 Campylobacter vaccine  
The present invention relates to vaccines comprising antiserum raised against a flagellaless Campylobacter strain for the prevention of Campylobacter colonization in animals. The invention also...
6780419 Basb029 polynucleotide(s) and polypeptides from neisseria meningitidis  
The invention provides BASB029 polypeptides and polynucleotides encoding BASB029 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic,...
6780420 Carrier protein having an adjuvant effect, immunogenic complex containing it, process for their preparation, nucleotide sequence and vaccine  
The invention relates to an adjuvant product which is intended to improve the activity of a molecule when administered to a host, characterized in that it comprises at least one part of the P40...
6776993 Tuberculosis vaccine  
The present invention relates to novel recombinant vaccines providing protective immunity against tuberculosis. Further, the present invention refers to novel recombinant nucleic acid molecules,...
6770284 Polypeptides and polynucleotides BASB040 from neisseria meningitidis and vaccine comprising said polypeptides and polynucleotides  
The invention provides BASB040 polypeptides and polynticleotides from Neisseria meningitidis encoding BASB040 polypeptides and methods for producing such polypeptides by recombinant techniques....
6770459 Immunogenic compounds  
The invention provides BASB081 polypeptides and polynucleotides encoding BASB081 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic,...
6767542 Compositions and methods for enhancing immunogenicity of antigens  
Compositions and methods for enhancing the immunogenicity of an antigen via fusion to a PEST-like amino acid sequence derived from a prokaryotic organism are provided.
6767545 Pseudomonas treatment composition and method  
A composition and method for treating or preventing infection by Pseudomonas aeruginosa is disclosed. The composition includes a P. aeruginosa pilin peptide modified to prevent oligomerization...
6764686 Modified immunogenic pneumolysin compositions as vaccines  
This invention relates to modified pneumolysin polypeptides that retain the immunogenic nature of pneumolysin but have reduced or undetectable hemolytic activity compared to native pneumolysin. The...
6764834 BASB019 proteins and genes from Moraxella catarrhalis, antigens, antibodies, and uses  
The invention provides BASB019 polypeptides and polynucleotides encoding BASB019 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic,...
6761891 Medicament for treating a manifested lyme disease  
A pharmaceutical composition for treating Lyme disease contains an antibody as an active agent which is specific for the 24 kDa antigen (OspC) of B. burgdorferi , preferably an antibody which is...
6759530 IBD-associated microbial nucleic acid molecules  
The present invention provides nucleic acid and amino acid sequence of the novel I-1 and I-2 polypeptides, which are associated with human inflammatory bowel disease (IBD). Methods of diagnosing...
6756043 Compositions and methods for detecting adult Taenia solium  
Compositions and methods for the detection of adult Taenia solium and the diagnosis and treatment of T. solium infection are described. The compositions contain one or more adult T. solium ...
6752992 Toxins active against pests  
The subject invention concerns materials and methods useful in the control of non-mammalian pests and, particularly, plant pests. In a specific embodiment, the subject invention provides new ...
6749858 Essential bacterial genes and their use  
Disclosed are two genes, termed “yphC” and “yqjK,” found in Streptococcus pneumoniae , which are essential for survival for a wide range of bacteria. These genes and the essential...
6746676 Chlamydia proteins and their uses  
Certain Chlamydia proteins have been found to be infection-specific and to be associated primarily with the vegetative Reticulate Body form of Chlamydia rather than with the refractile Elementary...
Matches 201 - 250 out of 517 < 1 2 3 4 5 6 7 8 9 10 11 >