Patents in Class 424/185.1

Matches 1 - 50 out of 66

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Match	Document	Document Title
1	7371809	Pharmacologically active antiviral peptides This invention relates to peptides having antiviral properties. The antiviral peptides comprise membrane transiting peptides, and active fragments and derivatives of such peptides. The antiviral pe...
2	7371388	Treatment of Sjogren's syndrome by administration of TR18 polypeptides The present invention relates to TR18 polypeptides. In particular, isolated nucleic acid molecules are provided encoding human TR18 protein. TR18 polypeptides are also provided as are vectors, host...
3	7368537	Subunit vaccine against respiratory syncytial virus infection The present invention relates generally to methods of treating or preventing RSV infections, and more specifically, to compositions, and the use thereof, comprising one or more RSV G protein immuno...
4	7368533	Polypeptide autoantigens associated with endometriosis This invention provides a polynucleotide encoding Repro-EN-1.0 and IB1, polypeptides associated with endometriosis. Auto-antibodies against Repro-EN-1.0 and IB1 have been found in subjects diagnose...
5	7368261	Conserved Neisserial antigens To ensure maximum cross-strain recognition and reactivity, regions of proteins that are conserved between different Neisserial species, serogroups and strains can be used. The invention provides pr...
6	7368119	Compositions and methods for WT1 specific immunotherapy Compositions and methods for the therapy of malignant diseases, such as leukemia and cancer, are disclosed. The compositions comprise one or more of a WT1 polynucleotide, a WT1 polypeptide, an anti...
7	7365156	PRO1316 polypeptides The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequ...
8	7365155	Immunoregulator The invention relates to the field of immunology, more specifically to the field of immune-mediated disorders such as allergies, auto-immune disease, transplantation-related disease or inflammatory...
9	7364743	Nucleotide sequence encoding PTD and CEA fusion protein, TAT-CEA fusion protein, anti-tumor vaccine and pharmaceutical composition for treating tumor comprising the fusion protein A nucleotide sequence encoding a fusion protein of PTD and CEA. The nucleotide sequence includes a CEA-encoding nucleotide sequence into which a PTD-encoding nucleotide sequence is inserted.
10	7364741	Peptides of human Papilloma virus for use in human T cell response inducing compositions A peptide comprising an amino acid sequence derived from a human papilloma virus (HPV) protein, wherein said amino acid sequence has the ability to bind to a human Major Histocompatibility Complex ...
11	7364740	Molecular differences between species of the M. tuberculosis complex Specific genetic deletion are identified in mycobacteria isolates, including variations in the M. tuberculosis genome sequence between isolates, and numerous deletion present in BCG as compared t...
12	7361637	Hypotensors There are provided a method for selection of a substance which is capable of controlling activation of prorenin where an adjusting ability of the activation of prorenin by protein-protein interacti...
13	7361352	Influenza immunogen and vaccine A chimeric, carboxy-terminal truncated hepatitis B virus nucleocapsid (HBc) protein is disclosed that contains an immunogen for inducing the production of antibodies to the influenza M2 protein. An...
14	7361351	Method for sensitizing bovine mammary cells to respond to LPS Studies in mice and humans indicate that membrane CD14 (mCD14) on the cell surface of monocytes, macrophages, and PMN mediates the activation of these cells by LPS. The soluble CD14 (sCD14) present...
15	7361350	Use of an IL-1 antagonist for treating arthritis Methods of treating, inhibiting, or ameliorating arthritis, including rheumatoid arthritis, osteoarthritis, psoriatic arthritis, ankylosing spondylitis, or juvenile rheumatoid arthritis, in a human...
16	7361349	Peptide, immunogenic composition and vaccine or medical preparation, a method to immunize animals against the hormone LHRH, and analogs of the LHRH tandem repeat peptide and their use as vaccine A peptide that comprises a modified tandem GnRH decapeptide sequence which allows for a testosterone level that is essentially nondetectable after vaccination with the peptide in a suitable dosage ...
17	7354991	Peptides for the diagnosis of schizophrenia Short peptides are provided, which bind to a body fluid sample obtained from a schizophrenic patient at a substantively higher level than to a body fluid sample obtained from a non-schizophrenic in...
18	7354588	Functional derivatives of ICAM-1 with altered ability to bind LFA-1 or HRV The present invention relates to intercellular adhesion molecules (ICAM-1) which are involved in the process through which lymphocytes recognize and migrate to sites of inflammation as well as atta...
19	7351686	Method for neuronal protection in amyotrophic lateral sclerosis by a vaccine comprising Copolymer-1 or Copolymer-1 related peptides A vaccine for reducing disease progression, and/or protection of motor nerve degeneration, and/or protection from glutamate toxicity in motor neurone disease (MND), particularly amyotrophic lateral...
20	7351570	HDV nucleic acid molecules and applications thereof The invention concerns nucleic acid molecules derived from novel hepatitis D virus strains or isolates constituting genotypes different from known I, II and III genotypes, their fragments, correspo...
21	7351416	Vaccines comprising acapsular P. multocida hyaE deletion mutants Acapsular hyaE deletion mutants of P. multocida can be administered to mammals, particularly ungulates, or birds to provide protective immunity against wild-type P. multocida, e.g., to prevent ...
22	7348405	PRO10274 polypeptides The present invention is directed to PRO10013 polypeptides.
23	7348010	Vaccine against cancer diseases that are associated with the her-2/neu oncogene The present invention relates to peptides of the extracellular domain of a HER-2/neu protein, conjugates comprising said peptides linked to an immunogenic carrier, compositions thereof, nucleic aci...
24	7348009	Recombinant allergen with reduced enzymatic activity The present invention provides a novel treatment for allergy comprising a recombinant allergen with reduced enzymatic activity, thereby reducing the potential for an allergic response upon contact ...
25	7348007	Mage C2 antigenic peptides and uses thereof This invention relates to isolated peptides derived from MAGE-C2, nucleic acid molecules that encode MAGE-C2 and the isolated peptides derived from MAGE-C2, expression vectors comprising the nuclei...
26	7344724	UspA1 and UspA2 antigens of Moraxella catarrhalis The present invention discloses the existence of two novel proteins UspA1 and UspA2, and their respective genes uspA1 and uspA2. Each protein encompasses a region that is conserved between the two ...
27	7344721	Polypeptide for the treatment of cancer and a method for preparation thereof This invention characterizes the specific peptide fragment derived from specially prepared zinc charged fetuin and a method of preparation thereof, wherein the fragment was found to contain an apop...
28	7341730	Inhibitors of angiogenesis and tumor growth This invention provides for polypeptides that have surprising anti-angiogenic activity. These peptides are derived from Saposin B, a previously known protein involved in the hydrolysis of sphingoli...
29	7341726	Modified HCV peptide immunogens Provided are an isolated peptide having the amino acid sequence DLMGYIPAV (SEQ ID NO: 1), an isolated HCV core polypeptide comprising an L→A substitution at amino acid position 139, an isolated H...
30	7341724	Polypeptide for the treatment of cancer and a method for preparation thereof This invention characterizes the specific peptide fragment derived from specially prepared zinc charged fetuin and a method of preparation thereof, wherein the fragment was found to contain an apop...
31	7339024	PRO1772 polypeptides The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequ...
32	7338766	Compositions and methods for treating malaria with cupredoxin and cytochrome The present invention relates to cupredoxin and cytochrome and their use, separately or together, to inhibit the spread of parasitemia in mammalian red blood cells and other tissues infected by the...
33	7335737	Ovary-specific genes and proteins Ovary specific proteins O1 180, O1 184 and O1 236, polynucleotides encoding them, antibodies which are immunoreactive with them and vectors and host cells containing O1 180, O1 184 or O1 236 are pr...
34	7335733	Tissue cement proteins from Rhipicephalus appendiculatus The present invention relates to tissue cement proteins produced by certain species of blood-feeding ectoparasites. These proteins and compositions comprising these proteins are particularly useful...
35	7335640	Administration of hypocretin-1 for treatment of narcolepsy The invention provides compositions and methods for treatment of sleep disorders. Such methods entail administering to the patient a therapeutically effective dosage regime of an agonist of a hypoc...
36	7335637	Biglycan and related therapeutics and methods of use The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with ...
37	7335636	SPRR1A and axonal regeneration The present invention provides polynucleotides, polypeptides, pharmaceutical compositions, and methods for modulation of nerve growth and regeneration.
38	7335505	Materials and methods relating to protein aggregation in neurodegenerative disease The present invention provides methods of proteolytically converting a precursor protein (e.g. tau) to a product fragment (e.g., a 12 kd fragment) in a stable cell line, wherein the precursor prote...
39	7335368	BVH-A2 and BVH-A3 antigens of group B Streptococcus Group B streptococcus polypeptides and polynucleotides encoding them are disclosed. Said polypeptides may be useful for the prophylaxis, diagnostic and/or therapy of streptococcal infection in ma...
40	7335360	Method and device for detecting feline immunodeficiency virus A method and device for determining a feline immunodeficiency virus infection or vaccination in an animal. The method includes contacting a biological sample from a felid with various FIV polypepti...
41	7335350	Chemokines mutants having improved oral bioavailability The oral efficacy of C—C chemokines containing a dibasic site in the 40's conserved cationic sequence, such as RANTES and MIP-1β, is improved by substituting at least one of the residues in the ...
42	7332595	DNA sequences encoding peptide sequences specific for the hepatic stages of P. falciparum bearing epitopes capable of stimulating the T lymphocytes The invention discloses isolated DNA sequences encoded by polypeptides characterized by the presence in their structure of one or more sequences bearing all or part of one or more T epitopes, and p...
43	7332473	Peptides and medicinal compositions containing the same This invention provides a pharmaceutical composition comprising, as an active ingredient, a peptide derived from a PACAP or VIP peptide or a pharmaceutically acceptable salt thereof. This invention...
44	7332172	Transformed bacteria producing CS6 antigens as vaccines Disclosed herein are antigens that stimulate protective antibodies against enterotoxigenic Escherichia coli . Also disclosed herein are proteins encoded by cssA and cssB genes as well as construct...
45	7332170	Classical swine fever virus virulence determinant and a novel classical swine fever vaccine Transposon linker insertion mutagenesis of a full-length infectious clone of the highly pathogenic classical swine fever virus (CSFV) isolate Brescia (pBIC) was used to identify genetic determinant...
46	7332167	Nucleic acid and amino acid sequences of hemoglobin-response genes in Candida albicans and the use of reagents derived from these sequences in the diagnosis of disseminated Candida albicans infection Three hemoglobin-response genes in the pathogenic yeast Candida albicans are disclosed. The expression of these genes is specifically induced when the organism is exposed to hemoglobin during dis...
47	7329730	PRO4348 polypeptides The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequ...
48	7329638	Drug delivery compositions The present invention relates to multicomponent compositions and methods of administering these compositions, which specifically translocate therapeutic molecules (e.g., drugs or prodrugs) across b...
49	7329500	Moraxella (Branhamella) catarrhalis polypeptides and corresponding DNA fragments The present invention relates to polypeptides of Moraxella ( Branhamela ) catarrhalis which may be used for prophy-laxis, diagnostic and/or therapy purposes.
50	7329410	Compositions and method for WT1 specific immunotherapy A method for enhancing or inducing an immune response to WT1 is disclosed. In particular, the method comprises administering to a patient an immunogenic composition comprising an isolated polypepti...

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