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6855524 |
Method for producing exopolysaccharides
The invention concerns a method for producing exopolysaccharides by fermenting micro-organisms characterised in that it consists in carrying out the fermentation in a nutrient medium comprising at...
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5843437 |
A82846 antibiotics
New glycopeptide antibiotic A82846, comprising A82846A, A82846B and A82846C, is produced by Nocardia orientalis strains NRRL 18098, NRRL 18099 and NRRL 18100. The A82846 antibiotics have activity...
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5567676 |
Glycopeptide antibiotics
The present invention concerns new antiobiotic substances demoninated de-acyl antibiotics A40926, de-acyl antibiotic A 40926P and antibiotic A 40926 amino glucronyl aglycon, and the use of these...
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5514662 |
Use of amphotericin B derivatives as protease inhibitors
The invention is directed toward the use of amphotericin B and derivatives thereof as inhibitors of serine-proteases and for applying these inhibitors for the production of medicinal products...
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5466450 |
Antiviral antibiotic BU-4224V
A novel antibiotic complex designated BU-4224V produced by fermentation of Kibdelosporangium albatum sp. nov. Strain R761-7. The complex may be separated chromatographically into bioactive...
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4950477 |
Method of preventing and treating pulmonary infection by fungi using aerosolized polyenes
This invention concerns a method of preventing a pulmonary infection by a fungus in a subject susceptible to infection by the fungus comprising administering to the subject an amount per dose in an...
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4935238 |
Antibiotic A 40926 complex and its pure factors PA, PB, A, B and B.sub.0
The present invention concerns a new antibiotic substance arbitrarily denominated antibiotic A 40926 complex and its factors antibiotic A 40926 factor A, antibiotic A 40926 factor B, antibiotic A...
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4910017 |
New compounds WF 2015 A and B
This invention relates to new compounds WF 2015 A and B which have immunosuppressing activity and antitumor activity, to a process for producing WF 2015 A and B by culturing a WF 2015 A and/or...
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4904470 |
Antibiotic F-0769, process for its production, and its use as a growth accelerating and feed efficiency increasing agent and as an antitumour agent
An antibiotic F-0769 having the following properties: (1) Outer appearance: White or light yellow powder, (2) Melting point: 245°-250° C., (3) Specific rotation: [α] D 25 =-37.5°...
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4902789 |
Process and composition for the purification of amphotericin B
A unique four-solvent system comprising methanol, dimethylformamide, methylene chloride and water is employed to provide an improved process for the purification and crystallization of amphotericin B.
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4868171 |
Antibiotic A 40926 N-acylaminoglucuronyl aglycons and antiobiotic A 40926 aglycon
The present invention concerns new antibiotic substances denominated antibiotic A 40926 N-acylaminoglucuronyl aglycon complex AB, antibiotic A 40926 N-acylaminoglucuronyl aglycon factor A,...
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4816480 |
Method for the preparation of feed premix in compositions of maduramicin
A method for the preparation of feed premix compositions of the antibiotic maduramicin which have improved stability of the antibiotic at elevated temperatures and the stable feed premix...
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4770876 |
Microbiological production of livestock growth-promoting agent
Promoting the growth of animals with a novel compound, named annomycin, by cultivation of Streptomyces strain BS 572, DSM 3817.
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4749571 |
Physiologically-active novel substance "Aldostatin" and production method thereof
A physiologically-active novel substance "aldostatin" having an estimated molecular formula of C 20 H 20 N 2 O 8 is produced by culturing an aldostatin-producing microorganism of the...
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4749568 |
Rubradirin treatment of methicillin-resistant staph
It has been discovered that rubradirin can be used to treat rubradirin-sensitive, methicillin-resistant staphylococcal infections.
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4695545 |
Culture and process for producing A41030 antibiotics
A hitherto undescribed microorganism, Streptomyces virginiae NRRL 12525, which upon culturing produces the A41030 antibiotic complex comprising several factors. The A41030 antibiotics produced show...
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4626503 |
Antitumor agents LL-D49194α.sub.1, LL-D49194β.sub.1, LL-D49194β.sub.2, LL-D49194β.sub.3, LL-D49194γ, LL-D49194δ, LL-D49194ε, LL-D49194ξ, LL-D49194η, LL-D49194ω.sub.1, LL-D49194ω.sub.2, and LL-D49194ω.sub.3
Antitumor agents LL-D49194α 1 , LL-D49194β 1 , LL-D49194β 2 , LL-D49194β 3 , LL-D49194γ, LL-D49194δ, LL-D49194ε, LL-D49194ξ, LL-D49194η, LL-D49194ω, LL-D49194ω 2 and LL-D49194ω 3 .
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4565781 |
Antibiotic, Spicamycin
An antibiotic, Spicamycin, having the physicochemical properties set forth below is produced by aerobically cultivating a Spicamycin-producing Streptomyces strain in a suitable culture medium, and...
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4542018 |
Teichomycin A.sub.2 pure single factors 1, 2, 3, 4 and 5 and method for their production
The invention refers to an individual antibiotic substance selected from the group consisting of Teichomycin A 2 factor 1, Teichomycin A 2 factor 2, Teichomycin A 2 factor 3, Teichomycin A 2 ...
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4476111 |
Antibiotic S/433 and process for its preparation
A new antibiotic, designated S/433, is disclosed which is produced in a microbiological fermentation under controlled conditions using a new strain of Streptomyces. This new antibiotic is active...
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4440752 |
Antibiotics Y-16482 α and/or Y-16482 β, a process for production thereof, and a pharmaceutical composition containing either or both of them
Antibiotics Y-16482 α and/or Y-16482 β, obtained by cultivating a strain belonging to the genus Pseudomonas and capable of producing Y-16482, process of producing either or both of them, and a...
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4396603 |
Novel antibiotic SF-2107 series substance and process for preparing the same
Disclosed is a novel antibiotic SF-2107 series substance consisting essentially of Substance SF-2107 A-1, Substance SF-2107 B and/or Substance SF-2107 C, each having the phisico-chemical properties...
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4359462 |
Antibiotic 67-121, a new polyene antifungal antibiotic produced by Actinoplanes caeruleus
A microorganism of the genus Acetinoplanes produces a novel complex of polyene antibiotics herein designated collectively Antibiotic 67-121 (and sometimes referred to as the Antibiotic 67-121...
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4341768 |
Antibiotic compounds
A novel peptide antibiotic complex designated herein as Bu-2470 is produced by fermentation of Bacillus circulans strain G493-B6 (ATCC 31,805). Complex Bu-2470 may be separated into four bioactive...
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4298599 |
Novel antibiotic BN-235 substance, and process for the production thereof
A novel antibiotic BN-235 substance and a process for making it are described, wherein the hydrochloride thereof has the following properties: Elemental analysis values: carbon 55.44% ...
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4298600 |
Antibiotic C-14482 A.sub.1 and method for producing same
A novel antibiotic C-14482 A 1 is produced by cultivating a microorganism belonging to the genus Nocardia and capable of producing Antibiotic C-14482 A 1 in a culture medium, whereby Antibiotic...
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4296101 |
Antibiotic kristenin
A new antibiotic, designated kristenin, is produced by the microorganism Bacillus subtilis. The antibiotic possesses activity against gram positive bacteria.
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4293546 |
Anthracycline antibiotics produced by Streptosporangium fragilis Shearer sp. nov. ATCC 31519
A novel anthracycline antibiotic complex, fragilomycin complex, is produced by the cultivation of a fermentation broth containing Streptosporangium fragilis Shearer sp. nov. ATCC 31519...
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4292309 |
Antibiotics C-14482 B.sub.1, B.sub.2 and B.sub.3
Novel antibiotics C-14482 B 1 , B 2 and B 3 are produced by cultivating a microorganism belonging to the genus Nocardia and capable of producing Antibiotics C-14482 B 1 , B 2 and/or B 3 in a...
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4289757 |
Method for treating inflammation
A method of treating inflammation comprising topical administration to mammals suffering from an inflammatory condition not associated with amicrobial component, employing selected antibiotics as...
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4278663 |
Antibiotic X-14868A, B, C and D
Antibiotic X-14868A having the following chemical structure ##STR1## and the pharmaceutically acceptable salts thereof is presented. Also presented is a fermentative method of producing the above...
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4272542 |
Use of di-sodium and di-potassium salts of dicarboxylic amino acids and tri- or di-sodium or potassium phosphate tartrate or citrate to improve the taste of in vivo hydrolysable esters of α-amino penicillins and cephalosporins
In-vivo hydrolysable esters of certain α-amino penicillins and cephalosporins have been rendered relatively tasteless by formulating into reconstitutable powders with a disodium or dipotassium...
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4212858 |
Antibiotic aculeacin-Aα, -Aγ, -Dα and -Dγ and methods for their production
Antibiotics aculeacin-Aα, -Aγ, -Dα and -Dγ are active against yeasts and fungi. They are produced by culturing the microorganism Aspergillus aculeatus NRRL 11270 in a nutrient medium containing...
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4209509 |
Substance SF-1739 derivatives, process for preparing the same and antibacterial compositions containing the same
Substance SF-1739 derivatives, Substance SF-1739 HP, Substance SF-1739 HP-C, Substance SF-1739 HP-F, Substance SF-1739 HP-3 and Substance SF-1739 HP-5, the physico-chemical properties of which...
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4205164 |
Antibiotic A201C, A201D and A201E
Antibiotics of the formula ##STR1## wherein R is α-3,4-di-O-methylrhamnosyl, are produced by the cultivation of Streptomyces capreolus NRRL 11429 under submerged aerobic fermentation conditions. A...
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4177265 |
Process for the purification of amphotericin B and A solubilizing media useful in that process
Acetone or methanol saturated with sodium iodide or sodium thiocyanate are useful solubilizing media for amphotericin B.
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4173629 |
Antibiotic S 31794/F-1
This invention provides S 31794/F-1 which is a useful anti-mycotic for combatting Candida albicans infections.
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4169887 |
Antibiotics produced by species of actinoplanes
A species of Actinoplanes, designated Actinoplanes deccanensis Parenti, Pagani and Beretta subsp. salmoneus Huang subsp. nov., ATCC 31355, when subjected to submerged aerobic fermentation, produces...
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4148880 |
Mixture of antibiotics produced by a species of actinoplanes
A species of Actinoplanes, designated Actinoplanes auranticolor ATCC 31011, when subjected to submerged aerobic fermentation under controlled conditions, produces a mixture of antibiotics which...
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4143141 |
Method of treating acne with antibiotic A201A
A method for the topical treatment of acne with antibiotic A-201A and A-201A compositions for acne are disclosed.
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4141974 |
Veterinary method employing certain aureolic acid compounds
The disclosure relates to a method for use in the practice of animal husbandry which comprises the oral administration to meat producing animals a compound of the aureolic acid group. Solid and...
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4132777 |
Antifungal compositions and method
Antifungal compositions useful for the treatment of ringworm and other fungal infections comprising an antifungally effective amount of natamycin and a non-toxic, pharmaceutically acceptable...
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4067966 |
Method of treating hypercholesterolemia with antibiotic SCH-16656
Orally administered compositions for altering lipid metabolism are described herein, these compositions containing an effective dose of antibiotic SCH-16656. Also the method of altering lipid...
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4039661 |
Antibiotic method of treating benign prostatic hypertrophy with SCH-16656
Orally administered compositions for treating prostatic hypertrophy are described herein. These compositions contain an effective dose of a pharmaceutical formulation containing antibiotic...
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4031208 |
Antibiotic
Strains of Actinoplanes produce an antibiotic substance upon aerobic cultivation. The antibiotic is sparingly soluble in water with a pronounced band in the UV absorption spectrum at 307 nm....
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4024246 |
Antibiotic A-22082 and process for production thereof
Antibiotic A-22082 is produced by submerged aerobic fermentation of Aspergillus nidulans NRRL 8112. Antibiotic A-22082 is an antifungal agent.
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4024245 |
Antibiotic A-30912 and process for production thereof
Antibiotic A-30912 complex, comprising microbiologically active, structurally related factors A, B, C, D, E, F and G, is produced by submerged aerobic fermentation of Aspergillus rugulosus NRRL...
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3997662 |
Antibiotics and their preparation
This invention relates to antibiotics designated 9865 RP, and its three constituents, hereinafter designated 13057 RP, 13213 RP and 13330 RP and their preparation.
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3997663 |
Antibiotic daunorubicin and its preparation
The invention provides the novel antibiotic known as daunorubicin (13057 RP) which has a powerful anti-cancer effect and is also an anti-bacterial agent. This antibiotic is a constituent of a...
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3978210 |
Antibiotic aculeacins
A family of antibiotics active against pathogenic yeasts and fungi comprises aculeacin-A, -B, -C, -D, -E, -F, and -G. These are produced from cultured broth of Aspergillus aculeatus FERM-P 2324.
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