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7601355 |
Compositions and methods for altering immune function
The present invention relates to molecules that stabilize and/or enhance CD154 activity, compositions comprising these molecules, methods for using these molecules and compositions (e.g.,...
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7165012 |
Method and system for computer-assisted test construction performing specification matching during test item selection
A method and system for constructing a test using a computer system that performs specification matching during the test creation process is disclosed. A test developer determines one or more test...
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6391851 |
Hydrochlorides of vancomycin antibiotics and process for producing the same
Process for producing a hydrochloride of a vancomycin antibiotic, comprising subjecting an aqueous solution of a hydrochloride of a vancomycin antibiotic to a primary freezing at from −1° C. to...
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6322286 |
Vibrating screed and method of making same
A vibrating screed for processing a floor layer, more particularly a so-called vibrating beam, of the type including a vibrating board (2), a vibrating mechanism (3) cooperating with the vibrating...
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6187800 |
Method for the prevention and treatment of mastitis
A method for treating or preventing mastitis in mammals is disclosed. The method contemplates the intramammary injection or dipping the teat with micrococcin antibiotics, preferably micrococcin P1...
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6103231 |
Antibiotic stalobacins
Novel antibiotic stalobacins H-1 and I-1 having physico-chemical properties as shown in Table 4 are provided, which are excellent antibiotics showing marked effects on Gram-positive bacteria.
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5736510 |
Antibiotics 10381v, w, x,y, z1, z2, pre-b and t
Antibiotics 10381v, w, x, y, z1, z2, pre-b and t are antibiotics producible by culturing the microorganism Streptomyces arginensis in an aqueous medium and isolation thereof. The structure of...
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5567676 |
Glycopeptide antibiotics
The present invention concerns new antiobiotic substances demoninated de-acyl antibiotics A40926, de-acyl antibiotic A 40926P and antibiotic A 40926 amino glucronyl aglycon, and the use of these...
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5547934 |
WF11243 substance
The present invention relates to a novel polypeptide having the following presumed structure: ##STR1## and the compound has both excellent fungicidal and protozoicidal effects.
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5514662 |
Use of amphotericin B derivatives as protease inhibitors
The invention is directed toward the use of amphotericin B and derivatives thereof as inhibitors of serine-proteases and for applying these inhibitors for the production of medicinal products...
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5466450 |
Antiviral antibiotic BU-4224V
A novel antibiotic complex designated BU-4224V produced by fermentation of Kibdelosporangium albatum sp. nov. Strain R761-7. The complex may be separated chromatographically into bioactive...
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5364624 |
WS7622A mono- or di-sulfate, process for preparation thereof and use thereof
A degenerative disease selected from the group consisting of cystic fibrosis, chronic bronchitis and bronchiectasia is treated by administering to a subject a therapeutically effective amount of...
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5239064 |
A59770 antibiotics
A novel antibiotic complex, A59770, individual factors and derivatives thereof, are provided. The A59770 compounds are useful as pesticides, particularly as rodenticides. Further provided are...
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5229362 |
Antibiotic A10255 complex and factors, and process and production therefor
Newly-discovered antibiotic A10255 factors B, C, E, F, G, H, and J are produced by submerged aerobic fermentation of Streptomyces gardneri NRRL 15537 and NRRL 18260 or an A10255-producing variant...
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5213797 |
A80407 antibiotics
New glycopeptide antibiotic A80407, comprising A80407A and A80407B, is produced by Kibdelosporangium philippinensis strains NRRL 18198, and NRRL 18199 or A80407-producing mutants of these strains....
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5192742 |
Compounds and compositions for the treatment of bacterial infections in animals
New glycopeptide antibiotics MM 49728, MM 55266, MM 55267/1, MM 55267/2 and MM 55268 are produced by fermentation of Amycolatopsis sp. NCIB 40089.
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5171740 |
Coumamidine compounds
A mixture of new coumamidine compounds are produced by a microorganism, belonging to the genus Saccharopolyspora. The compounds have antibiotic activity against a broad spectrum of bacteria.
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5167958 |
WS7622A, B, C and D substances, derivatives thereof, processes for preparation thereof and use for treatment of pulmonary emphysema and adult respiratory distress syndrome
A method of treating pulmonary emphysema or adult respiratory distress syndrome in a subject in need thereof which comprises administering to the subject an effective amount of WS7622A, B, C and/or...
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5165931 |
Peptifluorin and neopeptifluorin
Two related, novel antibiotic substances, peptifluorin and neopeptifluorin, are prepared by cultivation of strains of Pseudomonas fluorescens, A. T. C. C. No. 53,958 and A. T. C. C. No. 55,129,...
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5132112 |
HS-142-1 compounds
Compounds comprising a linear β1➝6 glucan esterified by caproic acid, the number of D-glucose residues being from 7 to 40 and the number of caproic acid residues being from 2 to 30, may be be...
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5013550 |
Antibiotics called "chloropolysporins B and C", a process for their preparation, and their therapeutic and veterinary use
Novel compounds, called chloropolysporins B and C, and salts thereof have antibiotic properties and would appear to be members of the class of glycopeptide antibiotics containing chlorine. They may...
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4999196 |
Compound DC-107 produced by Streptomyces sp.
A novel compound, DC-107, is produced by culturing a microorganism belonging to the genus Streptomyces. It is useful as a medicine because of its antibacterial and anti-tumor activity.
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4994270 |
A54145 antibiotics and process for their production
New peptide antibiotic A54145, individual A54145 components A, A 1 , B, B 1 , C, D, E and F and their pharmaceutically acceptable salts, are useful antibacterial agents which also improve growth...
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4956180 |
AB-006 antibiotics and process for their production
AB-006 Antibiotics and their AB-006 and AB-006b Antibiotic components, obtained by controlled aerobic culture of Streptomyces s.p. NCIB 12425, in an aqueous nutrient culture is disclosed. The...
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4940586 |
Skin permeation enhancer compositions using sucrose esters
A method for enhancing the transdermal flux of a transdermally deliverable drug through intact skin is described in which the drug is delivered simultaneously with sucrose monolaurate or a mixture...
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4935238 |
Antibiotic A 40926 complex and its pure factors PA, PB, A, B and B.sub.0
The present invention concerns a new antibiotic substance arbitrarily denominated antibiotic A 40926 complex and its factors antibiotic A 40926 factor A, antibiotic A 40926 factor B, antibiotic A...
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4902789 |
Process and composition for the purification of amphotericin B
A unique four-solvent system comprising methanol, dimethylformamide, methylene chloride and water is employed to provide an improved process for the purification and crystallization of amphotericin B.
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4885275 |
Vancomycin-HCL solutions and the lyophilization thereof
Gel-free concentrated aqueous formulations of vancomycin hydrochloride are provided which comprise the antibiotic salt at a concentration between about 12% and about 50% w/v and a gel-inhibiting...
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4868171 |
Antibiotic A 40926 N-acylaminoglucuronyl aglycons and antiobiotic A 40926 aglycon
The present invention concerns new antibiotic substances denominated antibiotic A 40926 N-acylaminoglucuronyl aglycon complex AB, antibiotic A 40926 N-acylaminoglucuronyl aglycon factor A,...
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4842857 |
Glyphomicins A and B
Cultivation of a strain of the microorganism Micromonospora sp. A.T.C.C. No. 53481, yields the novel antibiotic substance glyphomicin, which is a mixture of glyphomicin A and glyphomicin B.
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4804534 |
Antibiotic A 42867 and the addition salts thereof
A novel antibiotic, A 42867, is prepared by cultivating the strain Nocardia sp. ATCC 53492, or an antibiotic A 42867-producing mutant or variant thereof, under submerged aerobic conditions in the...
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4797280 |
Antibiotics produced by Kibdelosporangium aridum Shearer gen. nov., sp. nov. ATCC 39323
A novel antibiotic complex of "vancomycin-like" antibiotics, AAD 216 complex, is produced by the cultivation of a fermentation broth containing Kibdelosporangium aridum Shearer gen. nov., sp. nov....
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4701324 |
Novel cell-cidal antibiotic 82-85-8A and its production
Antibiotic 82-85-8A, or a pharmacologically acceptable non-toxic salt thereof, having the following physicochemical properties: (1) Elementary analysis: C 31 H 47 N 8 O 10 Cl (determined by...
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4696794 |
CL-1957D antibiotic compound and its production
A purified isolate of an actinomycete identified as ATCC 39366 is capable of producing the antimicrobial compound CL-1957D. The antimicrobial compound CL-1957D is produced by cultivating isolate...
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4695545 |
Culture and process for producing A41030 antibiotics
A hitherto undescribed microorganism, Streptomyces virginiae NRRL 12525, which upon culturing produces the A41030 antibiotic complex comprising several factors. The A41030 antibiotics produced show...
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4694069 |
Kibdelosporangium aridum SK&F-AAD-609
A novel subspecies of Kibdelosporangium aridum, subsp. largum (SK&F-AAD-609) produces AAD-216 antibiotics and AAD-609 antibiotics, the ADD-609 antibiotics differing from the AAD-216 antibiotics in...
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4670259 |
Compound FR-68504, production thereof and use thereof
The invention relates to a new compound, designated FR-68504. The compound has antitimor activities and is effective in the treatment of various tumors in both human beings and animals. There is...
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4656037 |
SPF-100 and process for the preparation thereof
Penicillin or related substances are added during the course of the cultivation of a streptococcus to recover SPF-100 from the culture broth. SPF-100 exhibits a broad range of molecular weight and...
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4650679 |
Animal feed block compositions
The present invention relates to animal feed block compositions containing a growth promoter, such as avoparcin, and an organic or mineral acid. The feed blocks of this invention exhibit improved...
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4626503 |
Antitumor agents LL-D49194α.sub.1, LL-D49194β.sub.1, LL-D49194β.sub.2, LL-D49194β.sub.3, LL-D49194γ, LL-D49194δ, LL-D49194ε, LL-D49194ξ, LL-D49194η, LL-D49194ω.sub.1, LL-D49194ω.sub.2, and LL-D49194ω.sub.3
Antitumor agents LL-D49194α 1 , LL-D49194β 1 , LL-D49194β 2 , LL-D49194β 3 , LL-D49194γ, LL-D49194δ, LL-D49194ε, LL-D49194ξ, LL-D49194η, LL-D49194ω, LL-D49194ω 2 and LL-D49194ω 3 .
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4601904 |
Antibiotics xylocandin A and xylocandin B
Cultivation of a strain of the microorganism Pseudomonas cepacia which has been deposited in the American Type Culture Collection as A.T.C.C. No. 39277, yields novel antibiotic substances...
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4597968 |
Antibiotic 13-384 complex from Micromonospora carbonacea var africana
The antibiotic 13-384 complex is elaborated by a new variety of Micromonospora carbonacea; namely Micromonospora carbonacea var africana NRRL 15099.
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4563442 |
Glycopeptide bioconversion products
New glycopeptide antibiotics of the formula: ##STR1## wherein W is the remaining portion of a glycopeptide antibiotic selected from actaplanin factors B 1 , B 2 , B 3 , C 1 , C 2 , C 3 , D 1 , D 2...
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4557933 |
Antibiotic called "chloropolysporin", a process for its preparation, and its therapeutic and veterinary use
A novel compound, called chloropolysporin, has antibiotic properties and would appear to be a member of the class of glycopeptide antibiotics containing chlorine. It may be produced by cultivating...
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4547462 |
Process for preparing substance having carcinostatic and immunostimulating activity
This invention relates to a process for producing a TF-500 substance having carcinostatic and immunostimulating activities, which comprises subjecting organisms belonging to the Fusobacterium genus...
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4534969 |
Method for improving lactation in ruminant animals
A method for improving lactation in lactating ruminants such as cattle or goats is disclosed. Said method utilizes the antibiotic Teichomycin A 2 or its physiologically acceptable salts, esters...
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4529542 |
Novel proteinous substance KUD-PC and its production
A novel proteinous substance KUP-PC, which is produced by culturing proteinous substance KUD-PC producing organisms belonging to the genus Streptosporangium. KUD-PC increases the antitumor activity...
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4507286 |
Polysaccharide having antiinflammatory and platelet antiaggregation activity
The extraction is described of a substance endowed with antiinflammatory and platelet antiaggregation activity, starting from the juice of plants of the species Ananas, Bromelia, Karatas, etc. of...
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4504467 |
Glycopeptide derivatives
Method of preparing compounds of formula 1: ##STR1## by oxidative deamination of a glycopeptide antibiotic of formula 2: ##STR2## the antibiotic being selected from A35512 factors A, B, C, E and H,...
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4497802 |
N-Acyl glycopeptide derivatives
N-Acyl-glycopeptide antibiotics having the formula ##STR1## and their salts are useful new antibiotics. The N-acyl actaplanin derivatives also increase feed-utilization efficiency and promote...
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