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4366147 |
Antibiotic A-7413 and process for preparation thereof
Antibiotic A-7413 complex, comprising a major microbiologically active factor A, and minor active factors B, C, and D, is produced by fermentation of Actinoplanes sp. NRRL 8122. The individual...
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4338302 |
Herbicolin and microbiological method for the preparation thereof
The antibiotic and antimycotic compound, herbicolin, is prepared from a strain of Erwinia herbicola by aerobic cultivation. Herbicolin consists of two chromatographically separable components,...
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4335108 |
Paulomycin A and B and preparation thereof
Disclosed and claimed is an improved fermentation process for preparing the known antibiotic U-43,120, herein referred to as paulomycin. Also disclosed and claimed are the novel and useful...
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4328211 |
Antibiotic Actinomadura-L-31 A, B
Antibiotic Actinomadura-L-31 A has the characteristics as the hydrochloride salt: appearance: white or pale yellow powder melting point: non-clear melting point specific rotation: [α] D...
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4313936 |
Biologically active substance, its preparation and compositions containing it
The new water-soluble substance designated by the number 41,200 RP, is obtained from cells of Micrococcus sedogenes, M 78 strain (NRRL B-3505), and is particularly useful in human or veterinary...
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4289757 |
Method for treating inflammation
A method of treating inflammation comprising topical administration to mammals suffering from an inflammatory condition not associated with amicrobial component, employing selected antibiotics as...
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4288429 |
Antibiotic planothiocins
A group of sulfur-containing antibiotics, planothiocin-A, -B, -C, -D, -E, -F and -G, are produced by culturing Actinoplanes sp. A12526 in a nutrient medium, and separating the thus-produced...
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4276286 |
Process for decreasing ammonia concentration in domestic animals or fowls
The invention relates to a process for decreasing the ammonia concentration in the interior of the body of domestic animals and fowls, thereby maintaining said animals and fowls in physiologically...
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4263404 |
Rifamycin R and microorganisms useful in the production of rifamycins
Novel rifamycin compounds, designated P, Q, R and U, produced by the fermentation of mutant strains of Streptomyces mediterranei.
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4259319 |
Antibiotic auromomycin, and process for production thereof
A new antibiotic designated as auromomycin is prepared from the culture broth of Streptomyces macromomyceticus, a macromomycin-producing strain, as yellow crystals. Auromomycin is recovered in pure...
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4250183 |
N-(Substituted amino)alkanoyl-aminoalkanoic acids and salts, their use and their compositions
N-substituted ω-aminoalkanoyl-ω-aminoalkanoic acids and their pharmacologically-acceptable salts (with a base) are useful, e.g., in pharmaceutical-composition form for the treatment or...
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4243661 |
Growth increasing agents
The present invention relates to a veterinary medicine containing multhiomycin as an effective ingredient and provides a medicine for promoting growth of animals including birds, fishes and...
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4237116 |
Combination of thiopeptin and rumensin to improve ruminant feed efficiency
Combinations of thiopeptin and rumensin are shown to synergistically increase the feed efficiency of ruminant animals. The combination is orally administered to ruminant animals in the feed of the...
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4235882 |
Antibiotic MM 4550A
It has been found that an antibiotic can be obtained by the fermentation of certain strains of Streptomyces olivaceus and related organisms and when pure this antibiotic is an extremely potent...
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4229436 |
Antibiotic G-6302
A novel Antibiotic G-6302 is produced by cultivating a microorganism belonging to the genus Pseudomonas and being capable of producing Antibiotic G-6302 in a culture medium to have Antibiotic...
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4225586 |
Antibiotic SB-72310
A novel Antibiotic SB-72310 is produced by cultivating a microorganism belonging to the genus Pseudomonas and being capable of producing Antibiotic SB-72310 in a culture medium to have Antibiotic...
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4221682 |
Tetrapeptides having analgesic activity
The polypeptides of the formula: ##STR1## wherein R 1 is hydrogen or lower alkyl; R 2 is hydrogen, lower alkyl, allyl, 2-methylpropenyl, cyclopropylmethyl or cyclobutylmethyl; R 3 is...
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4220639 |
Antibiotics SF-2050 and SF-2050B substances and production and use thereof
New antibiotics, SF-2050 substance and SF-2050B substance are produced by cultivating a microorganism Streptomyces sp. SF-2050 now deposited under FERM-P 4358 and under ATCC. 31450 in a liquid...
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4216206 |
Antibiotics S 53210/A-I, S 53210/A-II and S 53210/A-III
Antibiotics active against gram positive bacteria are produced from Microellobosporia brunea nov. Sp. King 1977.
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4209508 |
Antimicrobial substance C-3603 and process for preparing the same
Novel antimicrobial substance C-3603 was obtained from the culture of Streptococcus mutans C-3603, FERM-P No. 4128, ATCC No. 31383. The novel antimicrobial substance C-3603 shows a high...
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4205068 |
β-Lactamase inhibitor EM4615
A substance which inhibits the enzyme β-lactamase, produced by a wide range of microorganisms, is obtained when species of the microorganism Micromonospora are cultivated under aerobic...
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4201769 |
Antibiotic substances No. 17927A.sub.1 and No. 17927A.sub.2 and process for producing the same
New antibiotic substances named substance No. 17927A 2 and substance No. 17927A 1 produced by cultivation of substances No. 17927A 2 and No. 17927A 1 -producing microorganisms belonging to the...
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4189472 |
Antibiotic C-11924 F-1
A novel Antibiotic C-11924 F-1 is produced by cultivating a microorganism belonging to the genus Streptoverticillium and capable of producing Antibiotic C-11924 F-1 in a culture medium, causing the...
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4181714 |
Antibiotics Bacileucines A and B and process for production and use thereof
The present invention refers to novel antibiotics, Bacileucines A and B and use thereof, which are effective as agricultural and horticultural fungicides. Bacileucines A and B are produced from the...
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4180564 |
A-38533 Antibiotics and process for production thereof
Antibiotic A-38533 complex, comprising microbiologically active, related factors A 1 , A 2 , B and C, is produced by submerged, aerobic fermentation of a new Streptomyces sp., NRRL 11298. The...
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4175126 |
Polyheterocyclic-antibiotic
The new antibiotic of the formula: ##STR1## wherein R represents the group--CONH 2 , designated 35665 RP, possesses growth-promoting properties when added to animal feed.
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4169140 |
Antibiotics SF-1771 substance and SF-1771-B substance as well as the production of these substances
A new antibiotic SF-1771 substance is produced by cultivating a new strain, Streptomyces toyocaensis SF-1771, in a liquid culture medium under aerobic conditions. This antibiotic may be isolated...
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4146610 |
Antibiotics MM13902
It has been found that a novel antibiotic can be obtained by the fermentation of certain strains of Streptomyces olivaceus and related organisms. In addition to being a potent antibiotic this new...
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4136171 |
Antibiotic 354 and process for producing same
Novel antibiotic 354 (U-54,703) producible in a fermentation under controlled conditions using the new microorganism Streptomyces puniceus subsp. doliceus, NRRL 11160. This antibiotic is active...
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4125519 |
Polypeptides containing 3,4-dihydroxyphenylalanine
Homopolymers and copolymers containing the amino acid 3,4-dihydroxy-L-phenylalanine (dopa) have been prepared via the synthesis of a protected N-carboxyanhydride (NCA) of the amino acid. These...
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4113855 |
Composition of matter and process
Novel antibiotic formulations of antibiotic 354 (U-54,703) and their use in treating susceptible infectious disease in humans and animals.
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4103687 |
Use of haptoglobin for therapy of cerebral vasospasm
Haptoglobin is effective for preventing and remedy of human cerebral vasospasm when it is applied to spastic cerebral artery of the patient who is or has been suffering from cerebral vasospasm.
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4102999 |
Process for producing stable macromomycin powder
There is provided a process for producing a stable macromomycin (hereinafter often referred to as MCR) powder which comprises adding a stablilizer selected from the group consisting of saccharides,...
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4100117 |
Somatostatin analogs and intermediates thereto
The tetradecapeptide ##STR1## is described along with corresponding non-toxic pharmaceutically-acceptable acid addition salts as well as intermediates useful in the synthesis of the...
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4100273 |
Antibiotic substance from Actinoplanes sarveparensis CBS 305.76 (antibiotic L 13365)
A new antibiotic prepared from aerobic cultivation of Actinoplanes sarveparensis and a method for producing the same from a culture medium.
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4083963 |
Polypeptide antibiotic produced by a new subspecies of streptosporangium
A new sulfur-containing polypeptide antibiotic produced by two strains of Streptosporangium under submerged fermentation conditions is useful for the treatment of microbial infections and in...
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4078056 |
Antibiotic complex from micromonospora arborensis
Micromonospora arborensis produces a plurality of antibiotics named herein antibiotic 68-1147 complex, when cultivated under controlled aerobic conditions. Two of the antibiotics, antibiotic...
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4064013 |
Process for preparing thiostrepton
The antibiotic thiostrepton is produced by culturing aerobically Streptomyces laurentii A.T.C.C. No. 31255 in a culture medium containing carbon and nitrogen sources until thiostrepton is...
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4062944 |
Mixture of antibiotics produced by new species of micromonospora
A new species of Micromonospora, designated Micromonospora lacustris sp. nov. Routien, when subjected to submerged aerobic fermentation under controlled conditions, produces a mixture of at least...
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4061732 |
Control of lactic acidosis in ruminants
The nutritional disease, lactic acidosis, is successfully prevented by orally administering to the animal an effective amount of a sulfur-containing peptide antibiotic. In particular thiopeptin and...
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4051237 |
Glycopeptide antibiotics Bu-2231 A and B and process for producing same
A novel water-soluble basic glycopeptide antibiotic complex designated herein as Bu-2231 is produced by fermentation of a Bu-2231-producing strain of Streptoalloteichus hindustanus. Complex Bu-2231...
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4042683 |
Rifamycins P, Q and U
This invention is directed to rifamycin compounds which are produced by fermentation of Nocardia mediterranea ATCC 31064, ATCC 31065 or ATCC 31066 in an aqueous nutrient medium under aerobic...
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4039660 |
Antibiotic Y-G19Z D3 and the production thereof
A new antibiotic substance, designated Y-G19ZD3, is produced by the fermentation of a newly discovered microorganism Streptomyces organonensis Y-G19Z or a mutant thereof. The antibiotic substance...
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4038382 |
Alkyl esters of polyene antibiotics
The present invention provides a process for the preparation of alkyl esters of polyene antibiotics, wherein a polyene antibiotic is reacted with a diazoalkane in the presence of a basic substance....
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4031206 |
Antibiotics produced by species of pseudonocardia
A new species of Pseudonocardia, designated Pseudonocardia fastidiosa sp. nov. Routein, when subjected to submerged aerobic fermentation, produces two new antibiotics. Methods for the recovery and...
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4022884 |
Gardimycin and process for producing same
The antibiotic gardimycin and process for producing said antibiotic by fermentation of strains belonging to the genus Actinoplanes.
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3996355 |
Permanent suspension pharmaceutical dosage form
Permanent suspension dosage forms of drugs, particularly of the water-sensitive type, for administration without reconstitution are disclosed. The suspensions contain a drug dispersed in an...
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3988441 |
Antibiotic U-43,120 and process for preparing same
New antibiotic U-43,120 producible by the controlled fermentation of the new microorganism Streptomyces paulus, NRRL 8115. This antibiotic is active against Gram-positive and Gram-negative...
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3983230 |
Antibiotic siomycin A derivatives and production thereof
Antibiotic siomycin A derivatives produced by reaction of siomycin A with a dicarboxylic acid. The compounds have excellent characteristics, particularly in their solubility in comparison with that...
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3966911 |
Method for treating hypercholesterolemia with N-acetyl candicidin
Orally administered compositions for altering lipid metabolism are described herein, these compositions containing an effective dose of N-acetyl candicidin. Also the method of altering lipid...
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