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RE40059 |
Sensitive substance encapsulation
A process for stabilizing a sensitive substance; (a) plating a sensitive substance onto a solid carrier under a controlled atmosphere to reduce loss of the sensitive substance; (b) encapsulating...
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7311655 |
Method for manufacturing radioactive brachytherapy source material, brachytherapy source material and encapsulated radioactive brachytherapy source
The invention relates to a method for producing a radioactive brachytherapy source material comprising indium-114m in radioactive equilibrium with indium-114 as main radioactive isotopes. A new...
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7294329 |
Poly(vinyl acetal) coatings for implantable medical devices
A coating for a medical device, particularly for a drug eluting stent, is described. The coating includes a polyacetal-based polymer.
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7276254 |
Emulsion/aggregation polymeric microspheres for biomedical applications and methods of making same
A method of forming polymeric microspheres for biomedical applications includes forming polymeric microspheres by an emulsion/aggregation process from a precursor monomer species, and treating the...
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7265199 |
Poly-tri-fluoro-ethoxypolyphosphazene coverings and films
The present invention relates to an anti-thrombogenic, physically well-tolerated polymer and its use for manufacturing sheaths and films as a component of therapeutic devices for preventing...
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7264791 |
Method for preparing technetium-labeled antimony sulfide nanocolloid
The present invention relates to a preparation method for technetium-antimony trisulfide nanocolloid, more precisely, a preparation method for technetium-antimony trisulfide nanocolloid which is...
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7252840 |
Use of simple amino acids to form porous particles
Particles having a tap density of less than 0.4 g/cm 3 include a hydrophobic amino acid or salt thereof and a therapeutic, prophylactic or diagnostic agent or any combination thereof. Preferred...
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7235228 |
Fluorescent-magnetic nanoparticles with core-shell structure
This invention comprises nanoparticles for use with biosensors. The nanoparticles have core/shell architecture. The nanoparticles can be detected by two means, magnetic and optical by virtue of the...
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7217410 |
Surface modified protein microparticles
A microparticle contains a cross-linked protein shell, and a surface coating.
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7201891 |
Pharmaceutical preparation for the diagnosis of helicobacter pylori infection
A coated preparation for the detection of a H. pylori infection according to a urea breath test protocol which comprises a core composition containing at least an isotope C-labeled urea, an...
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7150867 |
Radionuclide-coated particulate material
This invention relates to a particulate material comprising an inorganic low density, radiation tolerant core coated with a radionuclide, processes for its production and a method of radiation...
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7081366 |
Uniform bead dosing from a stable dispersion
A primary antibody bead suspension for an enzyme-linked immunoassay (“ELISA”) procedure is formed of a quantity of primary antibody coated magnetic beads ( 3 ) uniformly dispersed and held in...
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7074386 |
Pressure induced swelling in microporous materials
A method for capturing specified materials which includes contacting a microporous material with a hydrostatic fluid having at least one specified material carried therein, under pressure which...
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7033571 |
Multiple stimulus reversible hydrogels
A polymeric solution capable of gelling upon exposure to a critical minimum value of a plurality of environmental stimuli is disclosed. The polymeric solution may be an aqueous solution utilized in...
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7001616 |
Microspheres for use in the treatment of cancer
The subject invention pertains to novel materials and methods for use in treating patients afflicted with oncological disorders, such as tumors. One aspect of the invention concerns methods for...
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6998105 |
Low density radionuclide-containing particulate material
The invention relates to a particulate material consisting of a low density radiation-tolerant glass and a radionuclide incorporated into the low density glass or coated on the low density glass,...
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6986880 |
Polymeric-matrix brachytherapy sources
Therapeutic sources for use in the practice of brachytherapy comprise a radioactive composite that includes (a) a polymeric matrix and (b) a radioactive powder, e.g. Pd-103 or I-125, consisting...
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6979491 |
Antimicrobial yarn having nanosilver particles and methods for manufacturing the same
The present invention provides a yarn with antimicrobial effects. The antimicrobial antifungal effect of the yarn is derived from nanosilver particles (diameter between 1 and 100 nm) which are...
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6979466 |
Nanoscale particles having an iron oxide-containing core enveloped by at least two shells
The invention relates to nanoscale particles suited especially for use in tumor therapy by hyperthermia. Said particles comprise a (preferably superparamagnetic) iron oxide-containing core and at...
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6919067 |
Compositions comprising a tissue glue and therapeutic agents
The present invention concerns compositions comprising a radiotherapeutic agent, or an agent which can be converted to a radiotherapeutic, and a tissue glue. The compositions of the present...
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6913767 |
Compositions for microencapsulation of antigens for use as vaccines
Methods and compositions are provided for the encapsulation of antigens in PLGA microspheres for use as vaccines. Such microspheres can also contain adjuvants. Mixtures of microspheres are provided...
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6911219 |
Partially acetalized polyvinyl alcohol embolization particles, compositions containing those particles and methods of making and using them
This relates to partially acetalized polyvinyl alcohol embolization particles suitable for implanting in the human body, to compositions containing those particles, and to methods of making and...
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6890512 |
Methods of preventing aggregation of various substances upon rehydration or thawing and compositions obtained thereby
The present invention encompasses methods to prevent aggregation of a wide variety of substances during freezing/thawing and/or dehydrating/rehydrating. The substances thus obtained and...
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6890457 |
Adhesive
An adhesive containing a far infrared radiation ceramic powder emitting far infrared rays and a radiation source ceramic powder emitting radiations and anions. The radiation source ceramic powder...
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6869588 |
Stimulus sensitive gel with radioisotope and methods of making
The present invention is a thermally reversible stimulus-sensitive gel or gelling copolymer radioisotope carrier that is a linear random copolymer of an [meth-]acrylamide derivative and a...
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6861016 |
Apparatus and method for preparing microparticles
Apparatus and method for preparing microparticles. An emulsion is formed by combining two phases in a static mixing assembly. The static mixing assembly preferably includes a preblending static...
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6746874 |
Reagent preparation containing magnetic particles in tablet form
Subject matter of the invention is a reagent preparation for binding components of a sample in the form of a tablet comprising a multitude of magnetic particles which are held together with the aid...
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6746661 |
Brachytherapy seed
A radiopaque brachytherapy seed for implantation into a subject includes a biocompatible component, a therapeutically active component including a non-radioactive drug, and a radiopaque marker. The...
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6730286 |
Manufacturing process to control particle size
A process for preparing a sterile injectable suspension of radiolabeled macroaggregated serum albumin suitable for use in scanning a mammalian patient consisting of: 1) purifying serum albumin...
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6709744 |
Bioactive materials
Bioactive substantially silica-free glass material with a hydroxyapatite layer thereon is described, as well as methods for producing hydroxyapatite on a borate glass.
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6706251 |
Colloid for scintigraphy
A new formulation of Tc-99m colloid is described. The new colloid contains a high ratio of perrhenate to thiosulphate, cysteine, and a prepared higher final pH than found previously. In preparing...
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6689043 |
Products and methods for brachytherapy
Radioactive sources, preferably radioactive seeds, for use in brachytherapy comprising a radioisotope within a sealed biocompatible container, wherein at least one part of a surface of the...
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6673863 |
Gel composition and methods of use
There is provided a gel composition having a silica powder and a non-volatile compound. The silica powder particles are spherical and porous. The silica powder has a specific gravity about 0.09 to...
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6670407 |
Biofunctional polymers prepared in supercritical fluid
Process for the preparation of a composition comprising a biofunctional polymer substrate and biofunctional material substrate adapted for use in or in association with the human or animal body,...
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6645464 |
Loading metal particles into cell membrane vesicles and metal particular use for imaging and therapy
Delivery of metal particles to living tissue, then applying external energy that interacts with the metal particles, is found to selectively increase the energy deposition and interaction...
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6635234 |
Preparation and use of radium-223 to target calcified tissues for pain palliation, bone cancer therapy, and bone surface conditioning
Processes for the preparation, prepared solutions, and the use of radium-223 for the treatment of calcified tumors, bone tumors, treatment of bones, bone surfaces and soft tissues is described.
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6592844 |
Preparation of protein microspheres, films and coatings
A process is described for preparing microspheres, films and coatings from protein or modified protein in which the protein product is stabilized by carrying out the preparation in the presence of...
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6589502 |
Radioisotope dispersed in a matrix for brachytherapy
Therapeutic sources for use in the practice of brachytherapy are fabricated from radioactive composites of a radioactive powder of palladium-103, yttrium-90, phosphorus-32 or gold-198 and a...
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6569688 |
Intravascular apparatus method
Intravascular apparatus and method for locally treating a patient's blood vessel, are provided. The apparatus includes an implanted carrier ( 2 ) for insertion into the vessel; and a biologically...
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6562318 |
Particular agents
A novel means of pharmaceutical delivery for therapy or prophylaxis or to assist surgical or diagnostic operations on the living body is provided by agents which undergo neuronal endocytosis and...
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6537518 |
Particulate material
A particulate material comprises hollow or cup-shaped ceramic microspheres having a diameter in the range of from 5 to 200 microns, the microspheres being formed from a base material comprising...
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6517809 |
Process for preparing a reactive pharmaceutical product for the detection of gastrointestinal disorder caused by bacteria in the gastrointestinal superior tract
The invention relates to the diagnosis in a human or lower animal subject of a gastrointestinal disorder of the upper gastrointestinal tract caused by bacteria using a breath test. In one aspect...
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6475466 |
Methods for treating endoleaks during endovascular repair of abdominal aortic aneurysms
Disclosed are methods for treating endoleaks arising from endovascular repair of abdominal aortic aneurysms. The disclosed methods involve the in situ sealing of endoleaks after placement of an...
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6455052 |
Enteric coating, comprising alginic acid, for an oral preparation
A composition for forming an enteric coating on a tablet, capsule or pellet for oral ingestion includes a liquid mixture of alginic acid particles dispersed in an aqueous solution of a binding...
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6455024 |
Inorganic materials for radioactive drug delivery
Radiotherapy agents which are solid or porous particles are described. The particles are of an inorganic material containing a suitable radionuclide and having an average particle diameter of about...
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6432381 |
Methods for targeting drug delivery to the upper and/or lower gastrointestinal tract
Particulate crystalline therapeutic substances are formulated with stabilizers to enhance contact between the crystalline therapeutic substances and the mucosal membranes to provide extended...
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6410680 |
Dendrimer constructs and metal complexes thereof having superoxide dismutase activity
A metal-dendrimer complex in which the metal active site is deep within the three-dimensional dendrimer construct, has superoxide dismutase-like activity. In particular embodiments the complex is a...
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6391279 |
Radioactive seeds for brachytherapy and a process for making the same
Novel radioactive seeds for brachytherapy and a reproducible method of manufacturing the seeds is described, wherein the seeds contain either Pd-103 or I-125 disposed within a cured resin matrix.
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6379648 |
Biodegradable glass compositions and methods for radiation therapy
A nonradioactive glass in particulate form adapted for radiation therapy in a mammal comprise a biodegradable rare earth-lithium borate glass material of a specified composition which, upon being...
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6376419 |
Osmium oxide composition
The present invention provides an osmium oxide composition comprising an osmium oxide microencapsulated in an aromatic polyolefin (hereinafter abbreviated as MCOsO x ), a method for preparation of...
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