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8759499 Lipids for transfection of Eukaryotic cells  
Compositions and methods for improved delivery of macromolecules into eukaryotic cells are provided. Fusogenic peptides from fusion proteins of non-enveloped viruses enhance the efficiency of...
8703097 Compositions and method for multimodal imaging  
Provided are signal modifying compositions for medical imaging comprising a carrier and two or more signal modifying agents specific for two or more imaging modalities. The compositions are...
8677649 Large-scale lyophilization device  
A device for large-scale lyophilization of pharmaceutical solutions in medical hollow bodies, includes a lyophilization device and at least one camera. Images of at least one pharmaceutical...
8673863 Glutathione-based delivery system  
A delivery system is provided. The delivery system includes a carrier or an active compound and a glutathione or a glutathione derivative grafted thereon. The invention also provides a compound...
8652836 Defective ribosomal products in blebs (DRibbles) and methods of use to stimulate an immune response  
Methods are disclosed for producing defective ribosomal products (DRiPs) in blebs (DRibbles) by contacting cells with a proteasome inhibitor, and in some examples also an autophagy inducer, thereby...
8636977 Integrin targeted synthetic ligands for diagnostic and therapeutic applications  
The present invention relates to a novel class of diagnostically or therapeutically effective compounds comprising novel aza-bicycloalkane based cyclic peptides, acting as a targeting moiety...
8623325 Azide modified charge sensitive channel proteins  
The present invention describes the modification of polypeptides, more particularly channel proteins with a thiol reactive agent so as to introduce an azide group. The present invention further...
8617514 Tumor-targeted nanodelivery systems to improve early MRI detection of cancer  
The present invention is in the fields of drug delivery, cancer treatment and diagnosis and pharmaceuticals. This invention provides a method of making antibody- or antibody fragment-targeted...
8569239 Glutathione based delivery system  
A delivery system. The delivery system includes a carrier or an active compound and a glutathione or a glutathione derivative grafted thereon. The invention also provides a compound including a...
8535712 Radiation sensitive liposomes  
The present invention relates to a radiation sensitive liposome, and the use of this liposome as carrier for therapeutic and diagnostic agent(s). In particular, the invention encompasses a...
8489337 Rejuvenation or preservation of germ cells  
Certain embodiments disclosed herein include, but are not limited to, at least one of compositions, methods, devices, systems, kits, or products regarding rejuvenation or preservation of germ cells...
8481003 Anti-CD74 immunoconjugates and methods  
Disclosed are compositions that include anti-CD74 immunoconjugates and a therapeutic and/or diagnostic agent. Also disclosed are methods for preparing the immunoconjugates and using the...
8435942 Methods for formulating stabilized insulin compositions  
A method of formulating insulin compositions comprises preparing a carrier having a phosphatidylcholine component which entraps insulin, stabilizing insulin compositions at room temperatures.
8367037 Anti-CD74 immunoconjugates and methods of use  
Disclosed are compositions that include anti-CD74 immunoconjugates and optionally a therapeutic and/or diagnostic agent. In preferred embodiments, the immunoconjugates comprise one or more...
8361494 Biomimetic iron-oxide-containing lipoprotein and related materials  
An engineered lipoprotein including (a) a core particle or a plurality of core particles, each core particle has (i) an inner part comprising a hydrophilic active agent and a hydrophilic portion of...
8343496 Anti-CD74 immunoconjugates and methods  
Disclosed are compositions that include anti-CD74 immunoconjugates and a therapeutic and/or diagnostic agent. Also disclosed are methods for preparing the immunoconjugates and using the...
8277823 Compositions and methods for stabilizing lipid based adjuvant formulations using glycolipids  
The present invention relates to liposome formulations that are physically stable. In particular the present invention relates to steric stabilization of cationic liposomes by incorporating...
8236770 Serum-stable amphoteric liposomes  
The invention relates to amphoteric liposomal formulations which are provided with great serum stability and are suitable for the intracellular delivery of oligonucleotides.
8148130 T4 bacteriophage bound to a substrate  
T4 bacteriophages are bound to substrates such as liposomes using a binder.
8137540 Methods and apparatus for continuous large-scale radiolabeling  
Disclosed are improved methods and apparatus for radiolabeling, particularly methods and apparatus for large scale in-line radiolabeling of products, such as proteins and antibodies.
8119101 Anti-CD74 immunoconjugates and methods of use  
Disclosed are compositions that include anti-CD74 immunoconjugates and optionally a therapeutic and/or diagnostic agent. In preferred embodiments, the immunoconjugates comprise one or more...
8067380 Glutathione-based delivery system  
A delivery system is provided. The delivery system includes a carrier or an active compound and a glutathione or a glutathione derivative grafted thereon. The invention also provides a compound...
8058256 Polymeric carrier for delivery of small interfering RNA  
A carrier for delivering small interfering RNA (siRNA) into cells includes a cholesterol residue covalently bonded to oligoarginine. Mixing the siRNA with the carrier produces a complex-containing...
8034385 Anti-ageing skin cosmetic  
The invention relates to a cosmetic based on various natural raw materials, which can be used to counter ageing processes of the human skin. The inventive cosmetic contains 0.1-5% by weight of an...
8029795 Targeted iron chelator delivery system  
A targeted iron chelator delivery system that comprises an iron chelator, a targeting agent and a lipid carrier, e.g., a liposome, is provided. The iron chelator delivery system may be used to...
7998462 Linkers for anchoring targeting ligands  
An improved linker which lacks chiral centers between a hydrophobic anchor for coupling to lipid-based particles and a targeting agent has suitable hydrophobic/hydrophilic properties for use in vivo.
7976743 Gas-containing liposomes  
The present invention provides gas-containing liposomes. In particular, the present invention provide methods of generating gas-containing liposomes where the gas is introduced under pressure, as...
7968129 Cosmetic skin care complex with anti-aging effect  
The invention relates to a cosmetic preparation which includes a skin care complex having an anti-ageing effect. The complex consists of liposomes comprising a mixture of cosmetic oil, extract of...
7968306 Method for measuring activity of a specific fraction of albumin  
Methods of measuring the SFA and sPLA2 activities in a mammalian subject are provided. The methods include: providing a substrate comprising a fluorescently labeled carboxylic acid and a negatively...
7875289 Compositions of less immunogenic and long-circulating protein-lipid complexes  
Provided are lipidic particles comprising phosphatidylcholine, phosphatidylinositol and cholesterol. Also provided are compositions comprising the lipidic particles and having associated therewith...
7875288 Method for treating blood coagulation disorders  
Provided is a method for treatment of blood coagulation disorders. The method comprises administering to an individual compositions comprising lipidic particles comprising phosphatidylcholine,...
7829064 Anti-CD74 immunoconjugates and methods  
Disclosed are compositions that include anti-CD74 immunoconjugates and a therapeutic and/or diagnostic agent. Also disclosed are methods for preparing the immunoconjugates and using the...
7763264 Composition and method for reducing the appearance of cellulite  
A topical composition for controlling the metabolism and/or distribution of subcutaneous fat and/or moderating the appearance of cellulite, comprising, as an active ingredient, phosphatidylcholine...
7749520 Compositions and methods for stabilizing lipid based adjuvant formulations using glycolipids  
The present invention relates to liposome formulations that are physically stable. In particular the present invention relates to steric stabilization of cationic liposomes by incorporating...
7749485 Liposomal assembly for therapeutic and/or diagnostic use  
Composition for diagnostic or therapeutic use which comprises an assembly comprising an active agent. The assembly comprises a liposome and a plurality of micellar components associated thereto,...
7722855 Extracellular vesicles from non-pathogenic amoebae useful as vehicle for transferring a molecule of interest to an eukaryotic cell  
The invention relates to membrane vesicles from non-pathogenic amoeba, in particular from the amoeba Dictyostelium discoideum, containing a molecule of therapeutic interest, to a method of...
7718160 Radiolabeled compounds and liposomes and their method of making and using same  
The invention, in one aspect, relates to radiolabeled compounds. The invention also relates to radiolabeled liposomes and methods of making and using thereof. The invention also relates to kits for...
7713514 Multicomponent assemblies having enhanced binding properties for diagnosis and therapy  
An organized mobile multicomponent conjugate (OMMC) and method of using to enhance binding of weakly binding compounds to a target. A lamellar structure containing at least two binding compounds is...
7704956 Glutathione-based delivery system  
A delivery system. The delivery system includes a carrier having a surface, an active compound comprising small molecule compounds or peptides for use as an analgesic encapsulated into the carrier,...
7700564 Glutathione based delivery system  
A delivery system. The delivery system includes a carrier or an active compound and a glutathione or a glutathione derivative grafted thereon. The invention also provides a compound including a...
7618641 Functionally reconstituted viral membranes containing adjuvant  
Vaccines directed against antigens such as membrane proteins from pathogens or tumor cells are disclosed. Also described are methods of forming reconstituted viral membranes, with membrane fusion...
7579156 Fluorescent phospholipase assay, phospholipase A2 inhibitor and stimulator, and the use thereof  
A fluorescent phospholipase assay is disclosed. Further disclosed are the identification of alpha-1-antitrypsin as a phospholipase A2 stimulator and phospholipase C inhibitor and the identification...
7468394 Sterile pharmaceutical composition and process for a solution of propofol emulsion having microbial growth retardation  
An oil-in-water propofol emulsion that contains soybean oil and egg lecithin, which provide a source of nutrition for microorganisms. Current products include additives to act as a microbial growth...
7371722 Pharmaceutical preparations and medicine capable of generating and/or containing thrombin  
The invention relates to a pharmaceutically active substance for producing a drug that is capable of generating thrombin or that contains thrombin and compositions comprising thereof. The...
RE40300 Carbon dioxide enhancement of inhalation therapy  
The present invention provides a method of increasing the deposition of aerosolized drug in the respiratory tract of an individual or animal, comprising the step of administering said aerosolized...
7368129 Amphiphilic materials and liposome formulations thereof  
Disclosed is a new structural class of amphiphilic molecules which incorporate a hydrophilic material or polymer attached, at spatially distinct sites, to at least two hydrophobic residues. Certain...
7354567 Method of encapsulating metal complex within liposomes  
An object of the present invention is to provide a method of producing liposome wherein a complex of a short half-life metallic radioactive nuclide such as 99mTc and CD is encapsulated, with...
7288243 Aerosol drug inhibition of lung metastases  
The present invention provides a method of inhibiting growth of lung metastases in an individual comprising the steps of administering a dose of a lipid-drug enhancer liposomal complex and, in...
7285289 Nanoparticle vaccines  
The present invention relates to nanoparticle vaccines comprised of a carrier, particularly polymerized lipids, having multiple copies of an antigen or combinations of different antigens displayed...
7264790 1,3-glyceride compound having two iodophenyl groups  
A compound represented by the following general formula (I) or a salt thereof: wherein Ar1 and Ar2 independently represent a substituted or unsubstituted aryl group having at least one iodine atom...
Matches 1 - 50 out of 211 1 2 3 4 5 >