Patents in Class 424/1.170

Matches 1 - 50 out of 62

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Match	Document	Document Title
1	7384623	High energy phototherapeutic agents High energy phototherapeutic agents or radiosensitizer agents comprised of a halogenated xanthene, or other related agents that exhibit a preference for concentration in biologically sensitive...
2	7374875	Peptides having affinity for the gp120 viral protein and use thereof The present invention relates to a family of peptides exhibiting high affinity and specificity for the viral protein gp120, to methods for producing these peptides, and to the use of these peptides.
3	7247501	Imaging and targeting tumors using sickle cells According to the present invention, there is provided a delivery vehicle including sickle red blood cells carrying a moiety. The moiety can be any type of diagnostic or therapeutic agent. The...
4	7186398	Fe/Au nanoparticles and methods A novel nanoscale, metal particle containing Fe atoms and Au atoms in solid solution. The particle is superparamagnetic with a large magnetic susceptibility at room temperature, is resistant to...
5	6913767	Compositions for microencapsulation of antigens for use as vaccines Methods and compositions are provided for the encapsulation of antigens in PLGA microspheres for use as vaccines. Such microspheres can also contain adjuvants. Mixtures of microspheres are provided...
6	6818199	Media and methods for enhanced medical imaging Metal nanoparticles are described that are useful for enhancing the contrast of x-rays or other radiation sources. A method is disclosed whereby the agents are administered intravenously or...
7	6783751	Method for labeling biopolymers using isotopes The invention relates to a novel method for the in-vivo labeling of biopolymers such as proteins, nucleic acids, lipids, carbohydrates and biodegradable plastic using isotopes, especially stabile...
8	6645464	Loading metal particles into cell membrane vesicles and metal particular use for imaging and therapy Delivery of metal particles to living tissue, then applying external energy that interacts with the metal particles, is found to selectively increase the energy deposition and interaction...
9	6379647	Use of mononuclear phagocytes in in vivo imaging of hypoxic/ischaemic tissue The invention relates to the imaging, preferably of hypoxic or ischaemic sites using mononuclear phagocytes. Specifically, the migratory behavior of the mononuclear phagocytes is exploited with a...
10	6361758	Cosolvent formulations Stable pharmaceutical formulations of a therapeutic agent, a low molecular weight alcohol and a glycol derivative are disclosed. Preferred formulations include...
11	6159443	X-ray guided drug delivery A method of delivering an active agent to a target tissue, particularly neoplastic tissue, vascular anomaly or tumor tissue, in a vertebrate subject. The method includes the steps of exposing the...
12	6106836	Container with freeze-dried vaccine components The present invention relates to a vaccine container that contains one or more freeze-dried vaccine components. The vaccine component or components are present in two or more freeze-dried bodies,...
13	6093381	Modulation of the sensitivity of tumor cells to chemotherapeutics Disclosed is a method for improving the treatment of a cancer patient which is undergoing (adjuvant) chemotherapy. Prior to or concomitant with the patient receiving adjuvant chemotherapy, the...
14	5997846	Method for detecting arthropods The present invention provides a method for detecting chitin-containing organisms on an area of a person or animal by contacting the particular area with a dye that is capable of biding to chitin...
15	5985281	Chemical compounds A two component system for therapeutic treatment of a host, having a first component comprising a targeting moiety capable of binding with a tumour associated antigen, linked to a mutated enzyme...
16	5814295	Determination of lymph nodes enriched in tumor reactive cells their proliferation and their use in adoptive cellular therapy The present invention is directed to a method for reliably determining lymph nodes enriched in tumor reactive cells, e.g., CD4+tumor-specific lymphocytes. This method includes the steps of...
17	5807840	Method for treating canine distemper The present invention discloses a method for treating patients having the CDV associated symptoms or animals carrying or infected by the canine distemper virus (CDV) or having antibodies against...
18	5785949	Measurement of liquid phase gastric emptying A drink adapted to be consumed by a patient to enable measurement of gastric emptying of the liquid phase, is a fruit juice having mixed and suspended therein a quantity of Spirulina platensis alga...
19	5725875	Protective skin composition A protective cream composition contains 15 to 40 wt % of an alkali metal fatty acid salt having from 8 to 18 carbon atoms, an effective amount of a topical agent such as an antimicrobial compound,...
20	5707602	Measurement of gastric emptying A biscuit adapted to be ingested by a patient to enable measurement of gastric emptying has added prior to baking Spirulina Platensis alga grown in a 13 CO 2 atmosphere. These single cell...
21	5703056	Non-invasive imaging of gene transfer The subject invention provides a method of detecting gene transfer to and expression in a target tissue of a host subject comprising: (a) administering to the host subject a transfer vector...
22	5690903	Loading and conjugating cavity biostructures Methods for the preparation and use of a biological delivery system are disclosed. The method of preparation includes the loading of a non-biological material into a biostructure having a...
23	5665328	Compounds, compositions and methods for binding bio-affecting substances to surface membranes of bio-particles Compounds, compositions, their methods of preparation and use in binding bio-affecting substances to the surface membrane of bioparticles, such as enkaryotic cells, without producing appreciable...
24	5635207	Methods for the preparation of blood substitutes for in vivo delivery In accordance with the present invention, there are provided compositions useful for the in vivo delivery of a biologic, wherein the biologic is associated with a polymeric shell formulated from a...
25	5420136	Eradication of pathogenic biological contaminants using non-azo naphthalimide dyes A class of predominantly hydrophobic non-azo N-substituted 1,8-naphthalimide compounds, each bearing, at its 3-position, a nucleofuge and, at its 4-position, a heteroatomic electron-releasing...
26	5292524	Blood platelet loaded with diagnostic or therapeutic-containing liposome or reconstituted Sendai virus The invention provides loaded platelets that include an absorbed loading vehicle having associated diagnostic or therapeutic agents. A method of loading platelets with diagnostic or therapeutic...
27	5279968	Method of labelling leucocytes with Tc-99m, d,1-HMPAO An improved method for radio-labelling leucocytes in vitro with Tc-99m d,1-HMPAO (Technetium-99m-d,1-hexamethyl propyleneamine oxime) for use in scintigraphic imaging of inflammatory lesions...
28	5276147	Compounds and complexes useful in medical imaging The subject of the present invention is compounds which correspond to the following general formula: ##STR1## in which R 1 and R 3 independently of one another represent H, an alkyl, alkenyl,...
29	5116597	Kit for the selective labeling of red blood cells in whole blood with .sup.9 TC Disclosed herein are a method and kit for the preparation of 99m Tc labeled red blood cells using whole blood in a closed sterile system containing stannous tin in a form such that it will enter...
30	5096693	Stable stannous chloride composition for labeling with radioactive technetium A non-radioactive labeling composition for preparation of a technetium 99m-labeled radioactive diagnostic agent, which comprises a small amount of a lyophilized product obtained from a stannous...
31	5093104	Method for labelling leucocytes with indium in-111 oxine An improved method for radio-labelling leucocytes in vitro with Indium In-111 oxide (Indium In-111 oxyquinoline) for use in scintigraphic imaging of inflammatory lesions and abscesses enhances the...
32	4992255	Capillary depletion method for quantifying transcytosis through the blood-brain barrier A method for quantifying transcytosis through the blood-brain barier by infusing a perfusate into the brain of a living mammal. The perfusate includes a radio-labelled test compound and a...
33	4935223	Labeled cells for use in imaging A process is provided for the labeling of viable eucaryotic cells. The process includes the steps of collecting, separating, and introducing a quantity of first type cells into a non-toxic media...
34	4789541	Method and composition for in vivo radiolabeling of red blood cells with .sup.99m Tc A composition containing stannous chloride and potassium perchlorate is suitable for oral administration to a patient for tinning red blood cells of the patient in vivo prior to labeling the red...
35	4762701	In vivo cellular tracking Methods of tracking cells in vivo and for determining in vivo cell lifetimes. Cells are labelled with cyanine dyes and detection is by measuring fluorescence, absorbance, or by detecting nuclear...
36	4755375	Method and kit for the selective labeling of red blood cells in whole blood with TC-99M Disclosed herein are a method and kit for the preparation of 99m Tc labeled red blood cells using whole blood in a closed sterile system containing stannous tin in a form such that it will enter...
37	4707544	Metal-isonitrile adducts for preparing radionuclide complexes for labelling and imaging agents A method for preparing a coordination complex of an isonitrile ligand and radionuclide such as Tc, Ru, Co, Pt, Fe, Os, Ir, W, Re, Cr, Mo, Mn, Ni, Rh, Pd, Nb and Ta is disclosed. The method...
38	4707352	Method of radioactively labeling diagnostic and therapeutic agents containing a chelating group A method of forming a therapeutic or diagnostic agent labeled with a radioactive metal ion, which comprises: contacting an unlabeled therapeutic or diagnostic agent, consisting of a substantially...
39	4705678	Sterile radioactive indium-containing aqueous solution The invention relates to a sterile aqueous solution for radioassaying a radioactive indium compound, which solution is entirely or substantially free from organic solvent, has a pH from 4 to 9,...
40	4666834	Leukocyte adherence inhibition assay A new technique is disclosed for assaying for the presence of invasive cancer. While based on leukocyte adherence inhibition, it is improved by using relatively long lived radio-labeled leukocytes,...
41	4624923	Metal-coated polyaldehyde microspheres A metal-containing polyaldehyde microsphere composed of a polyaldehyde microsphere to which a transition metal, e.g. Au, Ag, Pt, Pd, Tc, Fe, Ni or Co, is bound may be obtained in accordance with...
42	4619823	Radioactive iodine labeled metaraminol and diagnostic agent containing platelets labeled therewith A radioactive diagnostic agent which comprises platelets labeled with radioactive iodine atom-labeled metaraminol in an aqueous medium.
43	4500508	Radionuclide labeled lymphocytes for therapeutic use Lymphocytes labelled with β-emitting radionuclides are therapeutically useful, particularly for lymphoid ablation. They are prepared by incubation of the lymphocytes with the selected...
44	4497791	Method for labeling phagocytic cells Described herein is a process for labeling leukocytes and other phagocytic cells with labeled micellular particles involving incubating the cells with the micellular particles. Also described is a...
45	4466951	Intracellular trapping of therapeutics or tracer agents A method is provided for trapping therapeutic or tracer agents within cells to maximize their therapeutic effect or detectability. Primary amine containing therapeutic or tracer agents are bound by...
46	4452774	Isonitrile radionuclide complexes for labelling and imaging agents A coordination complex of an isonitrile ligand and radionuclide such as Tc, Ru, Co, Pt, Fe, Os, Ir, W, Re, Cr, Mo, Mn, Ni, Rh, Pd, Nb and Ta, is useful as a diagnostic agent for labelling liposomes...
47	4443426	Blood agent An agent for labelling blood cells using a radioactive complex of a radioactive metal with an N-oxide of pyridine which labelled blood cells are useful for in vivo imaging of blood cells for...
48	4372294	Method and apparatus for radiolabeling red blood cells A method and apparatus for radiolabeling red blood cells is provided which includes a syringe holder, a vial containing heparin, a vial containing technetium-99m and a catheter. The vials and...
49	4360510	Method for screening anti-tumor agents of the reticulo-endothelial stimulant class A procedure is disclosed for determining optimal doses, scheduling, routes of administration, the time for initiation, the magnitude and the duration of the anti-tumor effects, at various times...
50	4360509	Vivo radioassay process There is disclosed an in vivo radioassay process in which a radioactive chelate of indium and an 8-hydroxyquinoline is introduced into a warmblooded animal having an inflammatory reaction in an...

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