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7390462 |
Ratiometric fluorescent pH sensor for non-invasive monitoring
The present invention provides ratiometric fluorescent pH sensors for non-invasive, continuous monitoring of pH in such applications as fermentation processes. The ratiometric fluorescent pH...
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7390461 |
Broad spectrum optically addressed sensor
The present invention relates to a sensor for detecting chemical, biological, biochemical or other environmental stimuli, and includes a plurality of colloidal particles having chemical receptors...
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7387898 |
Apparatus and method for conducting assays
A multi-well assay plate structure ( 54 ) and assay apparatus and a method for performing chemical biochemical assays is described. The multi-well assay plate structure ( 54 ) defines a relatively...
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7387892 |
Biosensor using microdisk laser
A compact sensor for detecting the presence of biological or chemical species includes a microdisk laser and a wavelength shift detector. The microdisk laser is coated with a biological or chemical...
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7384795 |
Methods for verifying fluid movement
Methods for using semiconductor nanocrystals for determining fluid movement, fluid dilution and fluid removal are described. Methods for using semiconductor nanocrystals for monitoring and...
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7384791 |
Method of analyzing blood
A method of analyzing blood includes delivering a blood sample to a test device, applying a spatially varying electric field to the blood sample to provide a depleted cell concentration in a...
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7381571 |
Device and method for analyte detection
The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention...
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7381570 |
Device and method for multiple analyte detection
The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention...
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7381565 |
Flow cytometers and detection system of lesser size
Gas focusing flow cytometers are fabricatable employing simple and inexpensive manufacturing techniques. When such cytometers or conventional cytometers are combined with fiber optical light paths...
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7381370 |
Automated multi-detector analyzer
An automated analyzer for analyzing patient samples. The analyzer includes a plurality of cuvettes, which allow the samples to be mixed with various reagents. The analyzer includes one or more...
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7378283 |
Reaction monitoring of chiral molecules using fourier transform infrared vibrational circular dichroism spectroscopy
A method and apparatus to monitor the enantiomeric excess of chiral molecules participating in a chemical reaction. The method includes real time monitoring of the chemical reaction by obtaining a...
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7378270 |
Device for analyte measurement
A biochemical analysis instrument for multiple fluid analyses includes a housing. A sensor for sensing a reaction is disposed in the housing. An aperture is formed in the housing. A test tape...
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7378056 |
Circuits for in vivo detection of biomolecule concentrations using fluorescent tags
Methods are disclosed wherein labeled antibodies can be provided in vivo to tissue having antigens that specifically bind the labeled antibody. A first optical radiation is emitted into the tissue...
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7372572 |
Device for photometrically measuring the concentration of a chemical substance in a solution to be measured
An apparatus for photometric measurement of the concentration of a chemical substance in a solution, wherein a cuvette is provided containing the solution The cuvette is transmissive at least in...
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7371538 |
Microluminometer chip and method to measure bioluminescence
An integrated microluminometer includes an integrated circuit chip having at least one n-well/p-substrate junction photodetector for converting light received into a photocurrent, and a detector on...
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7368294 |
Method for optical detection of an adjoining of a material component to a sensor material with the aid of biological, chemical or physical interaction and device for carrying out said method (variants)
Method for detecting biological or chemical components in liquid or gas is based on measuring changes of the sensor layer thickness due to binding reactions. A plate or a gap with two surfaces of a...
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7368292 |
Differential reflection spectroscopy system and method for detecting explosives and other target materials
A system and method for identifying explosive or other target materials includes the steps of irradiating a first location and a second location spaced apart from the first location from a sample...
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7368281 |
Label-free evanescent-field detection of biological and chemical agents
An evanescent-field sensor system and method of using the system to detect either liquid- or airborne biological pathogens, chemical agents, and other harmful or toxic species is provided. The...
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7368086 |
Functionalized fluorescent nanocrystals, and methods for their preparation and use
Functionalized fluorescent nanocrystal compositions and methods for making and using these compositions are disclosed. The compositions are fluorescent nanocrystals coated with at least one...
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7368084 |
Flow cytometry for high throughput screening
The present invention, provides a flow cytometry apparatus for the detection of particles from a plurality of samples comprising: means for moving a plurality of samples comprising particles from a...
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7368082 |
Formulation of spotting solution to achieve uniform spot size and morphology and for nondestructive quality control of assay articles
This invention relates to spotting solutions for the production of assay articles with uniform spot size and morphology for the detection of biopolymers, comprising N-lauroyl sarcosine in a...
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7364898 |
Customized micro-array construction and its use for target molecule detection
The present invention relates to a detection and quantification method of different sets of target molecules ( 1, 3 ), being possibly present simultaneously in a biological sample by the use of a...
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7364850 |
DNA probe array
There is used at least one probe array obtained by arraying particles having various probes, respectively, fixed thereon (probe particles) in a definite order in a holder. A plurality of...
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7364701 |
Liquid homogenizing unit and high speed liquid chromatograph equipped with the same
A liquid homogenizing unit comprising a feed flow channel ( 56 ), a discharge flow channel ( 57 ), a first intermediate flow channel ( 58 ) communicating with the feed flow channel ( 56 ), and a...
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7361514 |
System and method for gas discharge spectroscopy
A system for identifying gases, the system having a plasma generator for generating a plasma using the gas to be identified and an array of detectors for detecting light emitted from the plasma. By...
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7361313 |
Methods for uniform metal impregnation into a nanoporous material
The methods, systems 400 and apparatus disclosed herein concern metal 150 impregnated porous substrates 110, 210. Certain embodiments of the invention concern methods for producing...
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7358079 |
Flow cell array and the utilization thereof for multianalyte determination
A one- or two-dimensional arrangement of flow cells is provided, as part of an array of sample compartments, with at least one inlet and outlet for each sample compartment, formed by a base plate...
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7358059 |
Simultaneous quantification of PIG-A associated proteins in red cells, platelets and leukocyte subsets using a single measurement
A single measurement can quantify phosphatidyl-inositol glycan complementation class A (PIG-A) associated proteins in red cells, platelets and the major leukocyte subsets present in blood...
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7354727 |
Method and apparatus for classifying B-lymphocytes
A B-lymphocyte classifying method includes the steps of (1) preparing a measurement sample by mixing a blood sample with a lysing reagent to lyse erythrocytes and to shrink the B-lymphocytes in the...
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7351588 |
Optical sensor with layered plasmon structure for enhanced detection of chemical groups by SERS
An optical sensor and method for use with a visible-light laser excitation beam and a Raman spectroscopy detector, for detecting the presence chemical groups in an analyte applied to the sensor are...
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7351574 |
Loading and ejection systems for biological growth plate scanner
The invention is directed to a biological scanner for scanning biological growth plates. A biological growth plate can be loaded into the biological scanner. Upon loading of a biological growth...
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7351374 |
Surface plasmon enhanced illumination apparatus having non-periodic resonance configurations
An apparatus configured to generate surface plasmon enhanced radiation comprises a metal film having first and second surfaces, and one or more resonance configurations formed in the metal film. An...
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7348181 |
Self-encoding sensor with microspheres
A microsphere-based analytic chemistry system is disclosed in which self-encoding microspheres having distinct characteristic optical response signatures to specific target analytes may be mixed...
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7344890 |
Method for discriminating platelets from red blood cells
A method for discriminating and quantifying platelets within an analyzed blood sample involves initially diluting the blood sample with a ghosting reagent that causes a change in the index of...
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7344678 |
Composite sensor membrane
A sensor may include a membrane to deflect in response to a change in surface stress, where a layer on the membrane is to couple one or more probe molecules with the membrane. The membrane may...
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7339673 |
Miniature optical readhead for optical diagnostic device
A miniature readhead for a photometric diagnostic instrument includes a housing of hand-held form factor, configured for receiving reagent sample media therein. The sample media has a plurality of...
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7333204 |
Method and device for analysing a gas likely to contain particles or suspended aerosols
The present method uses a spectrophotometric and/or ionisation detection device in which the gas to be analyzed and illuminated by a light source emitting in a range of wavelengths distinct from...
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7332344 |
Luminescence assays
A method of detecting an analyte is described in which an up-converting luminescent species that is excited by absorption of long wavelength light is provided as a donor of energy to an acceptor...
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7332329 |
Versatile substrate for SPR detection
A substrate for testing a carrier liquid for biomolecules using SPR or other techniques provides a metallic island surrounded by a hydrophobic layer, the islands being a location for the attachment...
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7332128 |
Fiber-optic dissolution systems devices, and methods
A dissolution system provides remote flow cells integrated into a manifold device. The manifold device communicates with liquid input and output lines associated with each flow cell, as well as...
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7329388 |
Electrophoresis apparatus having staggered passage configuration
An electrophoresis apparatus is generally disclosed for sequentially analyzing a single sample or multiple samples having one or more analytes in high or low concentrations. The apparatus comprises...
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7327451 |
Test strip system
The present invention provides a test field system, including a test strip with a test field, and a measuring device having a test strip receiver for measuring the test field. The test strip...
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7323347 |
Biosensor surface structures and methods
A biosensor surface with a low density of ligand-carrying tether molecules on a base layer. Also, surface plasmon resonance (SPR) devices have the biosensor surface attached to a thin gold layer...
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7320775 |
Exchangeable flow cell assembly with a suspended capillary
There is provided a flow cell assembly in which a shuttle supports and positions a capillary with its end extending beyond the shuttle. The flow cell assembly facilitates the replacement of a flow...
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7318909 |
Method and apparatus for enhanced evanescent field exposure in an optical fiber resonator for spectroscopic detection and measurement of trace species
An apparatus for detection and measurement of trace species in a gas or liquid sample. A sensor of a ring down cell formed from an optical fiber is exposed to the sample gas or liquid. A coherent...
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7318907 |
Surface plasmon enhanced illumination system
Methods and apparatus for producing small, bright nanometric light sources from apertures that are smaller than the wavelength of the emitted light. Light is directed at a surface layer of metal...
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7316899 |
Portable sensor array system
A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into...
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7314749 |
Method and apparatus for assay based on light diffraction
The present invention relates to a method and apparatus for detecting analytes in a medium, and more particularly the present invention relates to an assay based on light diffraction which appears...
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7314596 |
Apparatus for sensing coagulation of blood sample
A blood sample sensing apparatus includes a moving device which moves a sample container containing a blood sample to a sensing position, a turning mechanism which is connected to the moving device...
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7312090 |
Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
Methods are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also relates to optical...
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