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6861265 Flow cytometer droplet formation system  
A droplet forming flow cytometer system allows high speed processing without the need for high oscillator drive powers through the inclusion of an oscillator or piezoelectric crystal within the...
6858440 Tapered tubular optical waveguide probe for magnetic focusing immunosensors  
A waveguide probe for the detection of pathogens in a sample which comprises a laser, a first and a second tubes that converge at a point to form a proximal end. A magnet is positioned in the end...
6858184 Microlaboratory devices and methods  
Disclosed herein are apparatuses and devices, and methods for using and making the same, for use in performing desired activities in an automated, microscale format. Microparticles are ushered...
6855501 Transfer of arrayed chemical compositions  
Nucleotide preparations are transferred from a first substrate to a second substrate. One transfer method includes forming a patterned dry particulate deposition on a first substrate; positioning...
6855293 Fluids manipulation device with format conversion  
A fluid management apparatus includes a substrate having a first surface and a second surface opposite to the first surface. A plurality of fluid inlets, which are preferably media reservoirs, are...
6852547 Dynamically formed rotors for lock-in amplifier detection  
A method for measuring low levels of a substance in a sample includes the formation of a rotor from paramagnetic particles in a substantially uniform magnetic field. The rotor is rotated by...
6852541 Rapid assay for testing overall oxidative stress  
The invention relates to an assay for testing oxidative stress of a subject by measurement of oxidants in biological fluids such as urine, plasma, bioreactor medium and respiratory aspirants. There...
6852287 Microfluidic devices having a reduced number of input and output connections  
A system and method for reducing the number of input/output connections required to connect a microfluidic substrate to an external controller for controlling the substrate. In one example, a...
6852284 Liquid analysis cartridge  
The present invention provides an apparatus and method for storing a particle-containing liquid. The storage apparatus comprises a microfluidic convoluted flow channel having a plurality of article...
6849463 Microfabricated devices for the storage and selective exposure of chemicals and devices  
Microchip devices and methods of use are provided for the controlled exposure of a secondary device. In one embodiment, the microchip device include a substrate, a plurality of reservoirs in the...
6849414 Assay devices and methods of analyte detection  
Assay devices, kits, and methods for detection of one or more analytes in a sample are provided. The assay device features the controlled release of reagents and hence is particularly suitable for...
6849321 Surfaces with gradients in surface topography  
A method for preparing a metallized surface that possesses gradients in surface topography includes obliquely depositing a metal from a metal source onto a surface of a support. The surface of the...
6849236 Analyzer system for lid-covered sample containers  
An analyzer system has a base housing ( 1 ) and a sample tray ( 4 ) with at least two holding accommodations ( 5 ) for containers ( 32 ) of samples that are to be analyzed. The sample tray ( 4 ) is...
6846639 Method for detecting pathogens attached to specific antibodies  
The use of impedance measurements to detect the presence of pathogens attached to antibody-coated beads. In a fluidic device antibodies are immobilized on a surface of a patterned interdigitated...
6844198 Adsorptive method for determining a surface property of a solid  
A method of determining a surface property of solids in a plurality by contacting the solids with a fluid, measuring the radiation emitted, absorbed, or altered during adsorption of the fluid using...
6844196 Analysis of antioxidant in solder plating solutions using molybdenum dichloride dioxide  
The present invention relates to antioxidant analysis for solder plating solutions, by using a complexing solution comprising a molybdenum compound, such as MoO 2 Cl 2 , to form a highly colored...
6844150 Ultrahigh resolution multicolor colocalization of single fluorescent probes  
A novel optical ruler based on ultrahigh-resolution colocalization of single fluorescent probes is described. Two unique families of fluorophores are used, namely energy-transfer fluorescent beads...
6844149 Method, system, and apparatus for measurement and recording of blood chemistry and other physiological measurements  
A multi-component test strip for analyzing a plurality of blood components in a single blood sample. The test strip comprises a porous medium having a sample receiving region, and two or more...
6843963 Flow-through shear analyzer for biologically active molecules in liquid layers on surfaces  
The adsorption rate of proteins from solutions on surfaces in the region of interface layers is often so large that a depletion of the protein in the interface layer results. Due to this, the total...
6841131 Coupling to microstructures for a laboratory microchip  
What is described in this case is a laboratory microchip having microspray means whose direction of spray can be altered. The microchip has a substrate 40 which has a channel structure provided...
6841127 In-Situ Injection and materials screening device  
An apparatus for in-situ injection of one or more chemical components into a reaction chamber is disclosed. The apparatus includes a reaction chamber for receiving one or more libraries, each of...
6838292 Detection of biological warfare agents  
Methods and devices are provided for the detection of bacterial agents such agents as Bacillus anthracis and Clostridium botulinum with high sensitivity and selectivity. More specifically,...
6838287 Fluid mixture composition sensor  
An improved, affordable, and rapid fluid mixture composition or process monitor based on a thermal microstructure sensor. This is preferably accomplished with a microbridge sensor design that has...
6838055 Microchip  
Disclosed herein is a microchip provided with a specimen flow pass, a reagent flow pass, a confluence flow pass all of which are fine flow passes. The specimen flow pass allows specimen to flow...
6838053 Platinum silicide permeation layer device with microlocaions  
Electronically addressable microchips having covalently bound permeation layers and methods of making such covalently bonded permeation layers to microchips are provided. The covalent bonding is...
6838052 In-situ injection and materials screening device  
An apparatus for in-situ injection of one or more chemical components into a reaction chamber, comprising a reaction chamber for receiving one or more libraries including two or more samples; an...
6837942 Device and method for collecting and measuring chemical samples pad surface in CMP  
A chemical collection assembly and a method for using the assembly such that a chemical-mechanical polishing (CMP) pad used in the manufacture of semiconductor wafers can be assessed for...
6835351 Optical-chemical sensor  
An optical-chemical sensor which is suitable for the continuous and discontinuous determination by luminescence optics of the concentration of chloride in an aqueous sample and which comprises a...
6833274 Cortisol sensor  
Devices and methods for sensing and detecting cortisol levels in a fluid sample in real-time using a cortisol-imprinted polymer are provided. Also provided are hydration devices that include a...
6833267 Tissue collection devices containing biosensors  
The present disclosure provides tissue collection devices comprising biosensors that can be used for the detection of target analytes, such as nucleic acids and proteins, including antibodies and...
6833110 Test member  
A test member suitable for use in a test device for testing of analyte concentration in a fluid to be applied thereto comprises a base member ( 2 ) having a working area ( 4 ) to which the fluid is...
6830895 Method and kit for typing feline blood  
The present invention relates to a kit for determining feline blood type, wherein the kit includes a mixture comprised of a first monoclonal antibody and a second monoclonal antibody, wherein both...
6830729 Sample analysis instrument  
The present invention provides an apparatus and method for storing a particle-containing liquid. The storage apparatus comprises a microfluidic convoluted flow channel having a plurality of...
6829540 Drug discovery using multiple membrane mimetic affinities  
The measurement of multiple membrane affinities of test compounds, methods and compositions useful for acquiring data characteristic of such affinities, and a method and system for using such data...
6827903 Inert gas fusion analyzer  
A single pass analyzer includes multiple infrared sensors, a catalytic converter, a scrubber and a thermal conductivity cell all coupled in series to provide a single pass (i.e., one sample)...
6827900 Automatic stainer having a heating station  
An automatic stainer for staining specimens that are arranged on specimen slides and embedded in a medium, preferably in paraffin, is described. The automatic stainer has multiple reagent...
6825655 Method and arrangement for detecting changes of a magnetic response in magnetic particles  
A method for detecting changes of magnetic response of at least one magnetic particle provided with a external layer in a carrier fluid, comprising measuring the characteristic rotation time of the...
6821729 Devices for molecular biological analysis and diagnostics including waveguides  
An electronic device for performing active biological operations includes an optically confining region including a support substrate having a via and a chip disposed in a facing arrangement with...
6821724 Methods of genetic analysis using nucleic acid arrays  
The invention provides nucleic acid sequences which are complementary, in one embodiment, to a wide variety of murine genes. The invention provides the sequences in such a way as to make them...
6821485 Method and structure for microfluidic flow guiding  
A flow of liquids is carried out on a microscale utilizing surface effects to guide the liquid on flow paths to maintain laminar flow. No sidewall confining structure is required, minimizing...
6818400 Process for producing biochip  
The present invention aims at producing a biochip by an inkjet system without wasting a DNA solution. A biochip-producing solution is prepared to contain a combination of a DNA solution 6 to be...
6818184 Capillary array and related methods  
The invention provides methods and devices for detecting the presence of one or more target analytes in a sample employing a channel having affixed therein one or more binding partners for each...
6818183 Multi-temperature modular reactor and method of using same  
An apparatus and method for carrying out and monitoring the progress and properties of multiple reactions is disclosed. The method and apparatus are especially useful for synthesizing, screening,...
6818182 Device for processing samples of blood products  
A device for processing samples of blood products contained in tubes ( 18 ) closed by bungs ( 20 ) and loaded into cassettes ( 12 ), includes transfer component ( 10 ) designed to individually move...
6815216 Method for solid-phase microextraction and analysis, and a collector for this method  
The invention relates to a method for solid-phase microextraction and analysis of substances in a carrier fluid, in which a collector is brought into contact with the stirred fluid containing the...
6814938 Non-planar microfluidic devices and methods for their manufacture  
Non-planar microfluidic devices and methods for transferring fluids between vessels and microfluidic devices are provided. The devices may be contoured to physically contact non-planar vessels,...
6814935 Sample processing devices and carriers  
Methods and devices for thermal processing of multiple samples at the same time are disclosed. The assemblies include carriers and sample processing devices with process arrays that include...
6812457 Microfluidic system  
The present invention relates to a method for presenting an analyte of a liquid sample as an MS-analyte to a mass spectrometer. More particularly, the method comprises the steps of applying a...
6811973 Methods of using labeled probe molecules to quantify target molecules  
An assay system using labeled probe molecules to identify and quantify target molecules in a sample is disclosed. Where labeled probe molecules are present on a substrate such as a microarray, the...
6811969 Retentate chromatography—profiling with biospecific interaction adsorbents  
This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectivity...