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6921636 |
Method and apparatus for conducting an array of chemical reactions on a support surface
The invention provides apparatus and methods for determining the nucleotide sequence of target nucleic acids using hybridization to arrays of oligonucleotides. The invention further provides...
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6919200 |
Purification method and apparatus
A purification apparatus, kit and method for purifying DNA, RNA, proteins, antigens, antibodies and cells. The apparatus has a wand and a reservoir tube. The wand is made of a cap, a sample...
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6919045 |
Supply element for a laboratory microchip
A supply element for a microfluid microchip that can be used for chemical analysis has supply lines or reservoirs that serve to supply the microchip with substances or reagents. Both ends of the...
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6913931 |
Devices, methods and systems for low volume microarray processing
Devices, methods and systems for low volume microarray processing are disclosed. The microarray devices preferably include a plurality of reactant sites on a reactant surface. The reactant sites...
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6913929 |
Sexual fidelity and sex crime verification
A series of unique biochemical tests are combined to enable unskilled law enforcement and private investigation personnel to rapidly perform sex crime investigations on skin swipes and body fluid...
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6911183 |
Moving microdroplets
The movement and mixing of microdroplets through microchannels is described employing microscale devices, comprising microdroplet transport channels, reaction regions, electrophoresis modules, and...
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6908593 |
Capillary flow control in a fluidic diagnostic device
A medical diagnostic device for measuring an analyte concentration or property of a biological fluid includes capillary flow channels to convey a sample of the fluid from an inlet to a branching...
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6908594 |
Efficient microfluidic sealing
Improved sealing for microstructures in microfluidic devices having a plurality of units is provided by providing collars surrounding the openings to the microstructures, such as reservoirs. The...
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6905655 |
Modification of selectivity for sensing for nanostructure device arrays
An electronic system for selectively detecting and identifying a plurality of chemical species, which comprises an array of nanostructure sensing devices, is disclosed. Within the array, there are...
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6905653 |
Ion activity measuring device and method for producing the same
Determining a substance to be measured in a liquid sample by measuring the degree of coloring obtained when the substance is subjected to coloring reaction in terms of reflectance. Polymer beads...
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6905834 |
Bioluminescent bioreporter integrated circuit detection methods
Disclosed are monolithic bioelectronic devices comprising a bioreporter and an OASIC. These bioluminescent bioreporter integrated circuit are useful in detecting substances such as pollutants,...
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6902704 |
Injection pump assembly for a combinatorial reactor and related method
An injection pump assembly 10 in a chemical delivery system for simultaneously delivering reagents into a combinatorial reactor system having multiple injectors. The assembly 10 has a plurality...
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6895805 |
Hydrogen gas indicator system
A hydrogen gas indicator system that provides various substrate materials ( 4 ) that support hydrogen gas sensor ( 1 ) materials with discrete indicia ( 7 ) that provide information separate from...
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6895889 |
Airborne hazard detector
An airborne hazard detector including a housing having a slot in a side thereof for receiving a sheet of M8 chemical detection paper and a principal opening in the top thereof for the passage of...
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6893880 |
Analyte assays and devices
The present invention provides a method and a device that utilizes capillarity-mediated, chromatographic transport, for the qualitative or semi-quantitative analysis of selected analytes in liquid...
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6890729 |
Device and method for cytology slide preparation
This invention provides a novel device and method for preparing cytology slides. The device comprises a book-like form including an absorbent material and filter attached to the inside surface of a...
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6890484 |
In line test device and methods of use
The present invention recognizes that it can be desirable to have a sample receiving chamber integral to or engageable with a test platform, such as a test platform that includes a test strip. The...
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6887429 |
Apparatus and method for automated medical diagnostic tests
A method and apparatus for the automation of existing medical diagnostic tests is described. This method, called sequential injection analysis, makes use of a pump, multi-position selection valve,...
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6887671 |
Filtrate plate device and reversible-well plate device
This invention is directed to filtrate-holder and reversible-well collection plates composed of polypropylene and Teflon®, and to their use, in connection with compatible filter units, in...
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6887713 |
Bioactive chip mass spectrometry
The present invention is directed to a bioactive probe or chip (BC) that allows for the isolation of analytes, such as biomolecules, followed by modification or bioreaction on these said analytes....
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6887701 |
Microarrays and their manufacture
The microarrays of the present invention are prepared by using a separate fiber for each compound being used in the microarray. The fibers are bundled and sectioned to form a thin microarray that...
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6884394 |
Chemical indicator reader
A reader for a sterilization indicator having sterilizing agent sensitive indicia is described. The indicator allows a sterilization cycle to be monitored without the need for a user to...
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6884615 |
Microplate
A microplate having a base and wells is disclosed. The base has mark parts at least on one edge thereof. Each mark part is defined by notches cut in the edge of the base. The wells are provided in...
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6884592 |
Devices for analyte concentration determination and methods of manufacturing and using the same
Test strips for determining the concentration of at least one analyte, e.g., glucose, in a physiological sample and methods for their manufacture and use and are provided. The subject test strips...
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6884625 |
Kit and method for detecting food allergies
A method for detection of food allergies, by determining the presence of antibodies against specific antigens in a stool sample, involves diluting the specimen, introducing the diluted specimen to...
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6881581 |
High-density lipoprotein assay device and method
An assay device and method for measuring the concentration of HDL-associated cholesterol in a blood-fluid sample are described. The assay design is such that removal of non-HDL lipoproteins from a...
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6881317 |
Fractionation of macro-molecules using asymmetric pulsed field electrophoresis
A method and apparatus for fractionation of charged macro-molecules such as DNA is provided. DNA solution is loaded into a matrix including an array of obstacles. An alternating electric field...
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6881578 |
Analyte concentration determination meters and methods of using the same
Devices and methods for determining the concentration of an analyte in a physiological sample are provided. The subject devices are meters characterized by having an internal structure that...
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6881378 |
Multilayered analytical device
The invention concerns an analytical device containing at least two components in which at least two of the components are joined together with the aid of an adhesive, which is characterized in...
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6881379 |
Method for producing detection systems with planar arrays
The invention relates to a method for producing a detection system for detecting different analytes in a sample, characterised by the following steps: providing a planar or essentially planar...
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6878540 |
Device for lysing cells, spores, or microorganisms
A device for use with an ultrasonic transducer to lyse components of a fluid sample comprises a cartridge having a lysing chamber, an inlet port in fluid communication with the lysing chamber, and...
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6875185 |
Integrated confirmation sample in a body fluid test device and method of using
A lateral flow immunoassay contact chemical test device and method integrates sample collection, prescreen testing, and confirmation sample collecting and storing with a single device and a minimum...
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6875403 |
Method and apparatus for reproducible sample injection on microfabricated devices
Fixed volumes of samples are metered into the reaction channel of a microfluidic device using one or more slidable blocks having at least one fixed-length sample metering channel. In another aspect...
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6872358 |
Test strip dispenser
Devices for dispensing test strips and methods of using the same are provided. The subject devices are characterized by having a housing made of a cover and a base configured to retain a plurality...
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6872522 |
Broad specificity affinity arrays: a qualitative approach to complex sample discrimination
Described is a method for discriminating complex biological samples using an array of discrete biological sensing elements immobilized onto a solid support in which constituents bound to the sensor...
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6867049 |
Method for obtaining increased particle concentration for optical examination
The present invention relates to a method and apparatus for analyzing a blood or other biological fluid sample in a quiescent state, whereby particulate constituents of biological samples that...
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6867052 |
Biological material detecting articles of manufacture
The present invention relates to articles of manufacture inclusive of or in combination with a biological assay material, formed from a material capable of detecting and identifying the presence of...
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6864102 |
Device for performing an assay, a method for manufacturing said device, and use of a membrane in the manufacture of said device
The present invention relates to a device for performing an assay, which device comprises a substrate having oriented through-going channels, said channels opening out on a surface for sample...
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6863866 |
Self-contained devices for detecting biological contaminants
The present invention relates generally to self-contained devices and methods for detecting biological contaminants and, more particularly, to self-contained devices and methods for detecting...
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6861259 |
Method of using a cartridge for containing a specimen sample for optical analysis
A cartridge for holding a test specimen with an extremely small volume. The cartridge has a test chamber and a vestibule through which the test fluids are inserted into the test chamber. The...
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6861252 |
Sensors for the detection of an analyte
A sensor for the detection of an analyte includes a first reagent in one section of the housing and at least a second reagent in another section of the housing. The sensor also includes a reservoir...
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6858440 |
Tapered tubular optical waveguide probe for magnetic focusing immunosensors
A waveguide probe for the detection of pathogens in a sample which comprises a laser, a first and a second tubes that converge at a point to form a proximal end. A magnet is positioned in the end...
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6858182 |
Exhalation gaseous component gauge and a cellular phone equipped with function of measuring gaseous components
Disclosed is an exhalation gaseous component gauge including, in a palm-sized casing having exhalation taking-in and taking-out slots made on its front and rear sides, a semiconductor gas sensor so...
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6855293 |
Fluids manipulation device with format conversion
A fluid management apparatus includes a substrate having a first surface and a second surface opposite to the first surface. A plurality of fluid inlets, which are preferably media reservoirs, are...
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6855491 |
Device for rapidly diagnosing upper respiratory conditions
A device for detecting upper respiratory conditions. The device includes a support upon which are fixed discrete indicators of pH, protein content, nitrite content and/or leukocyte esterase...
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6852547 |
Dynamically formed rotors for lock-in amplifier detection
A method for measuring low levels of a substance in a sample includes the formation of a rotor from paramagnetic particles in a substantially uniform magnetic field. The rotor is rotated by...
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6852281 |
Gas indicator and gas sensor sheet
The invention designed to provide a gas indicator which can be applied over a broad range of gas concentration from a low concentration gas to a high concentration gas is concerned with a gas...
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6849237 |
Body fluid test apparatus with detachably mounted portable tester
A test apparatus having a base which performs a plurality of tests for different analytes in body fluids. A portable tester, such as a glucose meter, is detachably mounted to the base and provides...
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6849463 |
Microfabricated devices for the storage and selective exposure of chemicals and devices
Microchip devices and methods of use are provided for the controlled exposure of a secondary device. In one embodiment, the microchip device include a substrate, a plurality of reservoirs in the...
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6849414 |
Assay devices and methods of analyte detection
Assay devices, kits, and methods for detection of one or more analytes in a sample are provided. The assay device features the controlled release of reagents and hence is particularly suitable for...
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