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6586194 |
Method for assaying creatine kinase isozyme activity and assay reagent
A method for measuring the activity of creatine kinase MB (CK-MB) isozyme which is accurate, high in specificity, convenient, by inhibiting the activity of a mitochondria localized creatine kinase...
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6586253 |
Microchip based enzymatic analysis
A method for the detection of cell contents, the method comprising the steps of, introducing a cell into a channel in a microchip; lysing the cell to release cell contents into the channel; moving...
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6582970 |
Simple immunochemical semi-quantitative assay method and apparatus
The present invention relates to a simple immunochemical semi-quantitative assay method according to chromatography, which comprises trapping a certain amount of an analyte in a sample with a...
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6582969 |
Microdevices for high-throughput screening of biomolecules
Methods for the parallel, in vitro screening of biomolecular activity using miniaturized microfabricated devices are provided. The biomolecules that can be immobilized on the surface of the devices...
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6582658 |
Fiber optic moisture sensor
A fiber optic moisture sensor is described that can detect the presence or concentration of an analyte in an environment; additionally, a method for making the sensor is described. The invention...
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6579726 |
Instruments, methods and reagents for surface plasmon resonance
The invention provides methods and reagents for the enhancement of surface plasmon resonance (SPR)-based detection assays. The methods and reagents can be used in any molecular recognition assay...
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6579673 |
Patterned deposition of antibody binding protein for optical diffraction-based biosensors
The present invention provides an inexpensive and sensitive device and method for detecting and quantifying analytes present in a medium. The device comprises a metalized film upon which is printed...
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6576193 |
Device and method for collecting and testing fluid specimens
Devices and methods for collecting a fluid specimen and testing it are disclosed that avoid unduly exposing the tester to the specimen and eliminate the possibility of contaminating the remaining...
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6576473 |
Removable test kit and method of use for vapor compression systems
A field-installable and removable moisture and/or acid test kit and method is used for a vapor compression system. A moisture and/or acid indicator is provided in the test kit which is installed at...
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6576460 |
Filtration-detection device and method of use
The present invention relates to a filtration-detection device for detecting or quantifying an analyte in a test sample including a filtration device having a first binding material immobilized...
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6566051 |
Lateral flow test strip
The present invention provides a test strip having a first layer comprising a wicking member and a second layer comprising a capillary transfer plane member. The capillary transfer plane has a...
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6567214 |
Microscope slide having culture media and method for use
A microscope slide having a well formed therein, wherein the well is filled with culture media. The slide is designed for on-site collection, staining, and viewing of cells in biological fluid and...
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6565808 |
Line test device and methods of use
The present invention recognizes that it can be desirable to have a sample receiving chamber integral to or engageable with a test platform, such as a test platform that includes a test strip. The...
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6565815 |
Heat exchanging, optically interrogated chemical reaction assembly
The present invention provides a reaction vessel and apparatus for performing heat-exchanging reactions. The vessel has a chamber for holding a sample, the chamber being defined by a plurality of...
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6558958 |
Optical fiber evanescent field excited fluorosensor and method of manufacture
An optical fiber is tapered, preferably adiabatically, and has a material coated on it for chemical bonding with fluorophores. When the fluorophores couple with the material, evanescent radiation...
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6558625 |
Distribution device for automatic catalyst evaluation multi-reactors
The present invention relates to a distribution device intended for a gaseous effluent produced by a chemical reaction, comprising at least two inlet ways and two outlet ways. This device comprises...
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6558959 |
Analytical assay device and methods using surfactant treated membranes to increase assay sensitivity
An analytical device comprising a surfactant-treated porous reaction membrane having an exposed sample-contacting surface and at least one receptor area located in a limited region of the exposed...
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6555389 |
Sample evaporative control
Devices and methods are provided using microfluidic devices for manipulating small volumes and determining a variety of chemical and physical events. The devices rely upon an opening to the...
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6555390 |
Chromatographic assay or test device
A chromatographic assay or test device for detection and/or determination of an analyte in a test sample, comprises a base member, and a chromatographic medium located in or on said base member,...
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6555386 |
Apparatus for collecting a liquid sample
The apparatus for collection of a liquid sample (such as a sample of body fluid) includes a tube with a hollow bore extending longitudinally between a first open end and a second open end. The...
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6555387 |
Method for producing thin liquid samples for microscopic analysis
The present invention relates to the field of diagnostics by means of microscopic sample analysis, and specifically relates to a method and apparatus for preparing thin microscopic samples of...
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6555061 |
Multi-layer reagent test strip
A reagent test strip for measuring an analyte concentration in a biological fluid has a spreading mesh sandwiched between a support and a reagent matrix. The support has a through hole that is...
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6551841 |
Device and method for the detection of an analyte utilizing mesoscale flow systems
Disclosed are devices for detecting the presence of a preselected analyte in a fluid sample. The devices comprise a substrate microfabricated to define a sample inlet port, and a mesoscale flow...
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6551554 |
Counting compartment for biological investigations and a method for manufacturing such a counting compartment
Counting compartment having an inlet and an outlet, and including a bottom plate and a top plate which are held at a distance from each other by material particles which have the same size and are...
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6551555 |
Apparatus with a chemical indicator for indicating exposure to an oxidative sterilant or disinfectant
An apparatus for determining exposure to an oxidative sterilant is described. The apparatus includes a chemical indicator for indicating exposure to the oxidative sterilant and a biological...
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6551837 |
Method for testing soluble salt levels in a solution
A test kit for testing substrates for soluble salts including a test sleeve, a pre-measured volume of solvent solution, and a soluble salt measuring device. The test sleeve includes a generally...
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6551834 |
Detection of contaminants using self-contained devices employing target material binding dyes
A self-contained signal generating device and methods for using and making the same are provided. The device and methods may detect the presence of a number of different substances, such as...
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6548311 |
Device and method for detecting analytes
The invention relates to a method for detecting analytes and to a device for carrying out the method, for use for analysis or diagnosis in the fields of chemistry, biochemistry, molecular genetics,...
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6544796 |
System for producing multiple diagnostic test elements
A system for producing multiple diagnostic test elements has a support ( 1 ) with an analytical region ( 3 ) to which diagnostic test spots ( 8 ) are applied, one or several stop edges ( 11-13 )...
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6541269 |
Colorimetric test strips
A method and calorimetric test strip for determining analyte concentration are provided. The test strip includes an aperture exposing a face of an calorimetric indicator-bearing carrier....
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6540890 |
Biosensor
A biosensor is provided that comprises a substrate, a reagent positioned on the substrate, and a cover including a first surface coupled to the substrate and a second surface. The first surface is...
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6540962 |
Testing instrument for analyzing liquid sample
A test device 1 for analyzing a specific component in a test solution with a reagent by allowing the solution introduced via a feed opening 4 to react with the reagent maintained in a...
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6537501 |
Disposable hematology cartridge
The present invention provides an apparatus and method for storing a particle-containing liquid. The storage apparatus comprises a microfluidic convoluted flow channel having a plurality of...
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6537828 |
Immunoassay apparatus
An immunoassay device which comprises a Chromatography strip having a substrate adhered to the under surface thereof and a protective laminate adhered to the top surface thereof, wherein a space is...
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6537821 |
Method and apparatus for detecting, measuring, and/or removing chlorine gas contamination in gaseous chlorine dioxide
Method and apparatus for detecting the presence of or removing chlorine in a gaseous product stream from a chlorine dioxide generator by mixing gaseous ammonia or ammonia vapors with the product...
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6537496 |
Functional overlay for flexible objects in particular for diagnostic test strips
A flat-shaped functional overlay for at least one region of a flat-shaped flexible object which does not form a fold when the sandwich composed of the flexible object and overlay is bent towards...
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6534006 |
Chemical indicator for determining the adequacy of a liquid sterilization process
A sterilization indicator that presents a visually distinct and uniform color transition after having been passed through sterilizing conditions. This sterilization indicator has a base layer with...
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6534017 |
Test element storage device
The invention concerns a magazine for storing test elements ( 1 ) with one or several test zones ( 3 ) which are attached adjacent to one another on a rectangular support, wherein the magazine has...
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6531095 |
Cartridge-based analytical instrument with optical detector
An analytical instrument for analyzing fluids. The instrument includes a cartridge carousel assembly which receives analytical cartridges. The cartridges are self-contained units which incorporate...
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6528325 |
Method for the visual detection of specific antibodies in human serum by the use of lateral flow assays
This invention discloses a method and composition for detecting the presence of class specific antibodies reactive with analytes such as bacteria, allergens, autoimmune antigens, viral proteins,...
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6528321 |
Opposable-element chromatographic assay device for detection of analytes in whole blood samples
A chromatographic assay device according to the present invention provides a unidirectional immunoassay for an analyte in a whole blood sample with improved sensitivity and freedom from...
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6524530 |
Sample collecting member and wiping inspection instrument
A wipe inspecting instrument comprising a sample collecting member and a reactive reagent container. The sample collecting member comprises a tubular main body having both upper and lower ends...
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6524864 |
Test strip for simultaneous detection of a plurality of analytes
A test strip for simultaneously measuring a plurality of analytes in blood or other fluids comprising a plurality of reagent pads containing reagents specific to particular analytes located on a...
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6521181 |
Microfabricated electrochemiluminescence cell for chemical reaction detection
A detector cell for a silicon-based or non-silicon-based sleeve type chemical reaction chamber that combines heaters, such as doped polysilicon for heating, and bulk silicon for convection cooling....
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6521182 |
Fluidic device for medical diagnostics
A fluidic medical diagnostic device permits measurement of analyte concentration or a property of a biological fluid, particularly the coagulation time of blood. The device has at one end a sample...
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6514769 |
Multiple analyte assay device with sample integrity monitoring system
An assay device, a fluid analyte sample separator device and methods for use of thereof for determining whether the integrity of a fluid analyte sample has been compromised and for...
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6514465 |
Apparatus for receiving an object, arrangement for transporting and for receiving and object and method for their operation
A support surface ( 3 ) is bordered on at least two sides by fins while mounted at an opposite corner is a clamping device comprising a slide ( 6 ) which can be drawn back from a starting position...
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6514765 |
Acid test kit and method of use
An acid test kit uses an indicator paper in a transparent tube which is easily and temporarily inserted in a Schrader-valve at a compressor suction inlet of a refrigeration system. The simplicity,...
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6509196 |
Compensation for non-specific signals in quantitative immunoassays
Methods for quantitatively measuring the amount of an analyte of interest in a fluid sample are disclosed. The methods involve providing a membrane having an application point, a detection zone,...
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6503757 |
Analytical system and method
An analytical or preparatory microfluidic system is disclosed which generally comprises a base unit comprising a first adapter interface array; a first adapter plate selected from a set of a...
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