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5658723 |
Immunoassay system using forced convection currents
An analytical system for performing an immunoassay is provided wherein the system contains an element that uses capillary action to draw a sample into a reaction chamber charged with reagent...
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5658801 |
Medical test kit
A medical diagnostic test kit includes a rectangular flat bottom member having an external raised flange and an internal raised flange forming a cavity therein; an elongated dry chemistry membrane...
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5656448 |
Dipstick immunoassay device
The invention pertains to dipstick immunoassay devices. The device comprises a base member and a single, combined sample contact zone and test zone, wherein the test zone incorporates the use of...
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5648274 |
Competitive immunoassay device
A chromatographic assay device for detection and/or determination of an analyte in a competitive immunoassay gives a semiquantitative or quantitative indication of analyte concentration in a single...
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5648047 |
Device for colorimetric detection of explosives and narcotics
A hand-held device for rapid colorimertic detection of explosives, narcotics, and other chemicals which can be accurately operated by non-skilled personnel and perform numerous tests in a quick...
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5641639 |
Binding assay device
A device for performing an enzyme-labelled binding assay comprises an absorbent material and a developing solution containing a substrate for said enzyme, wherein the absorbent material is provided...
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5641688 |
Immunoassay including washing a slide at different locations
A method of separating bound labeled indicator from free labeled indicator in a layer of a test element for immunoassay. The method comprises a) depositing sample containing a target...
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5637469 |
Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems
Disclosed are devices for detecting the presence of a preselected analyte in a fluid sample. The devices comprise a substrate microfabricated to define a sample inlet port, and a mesoscale flow...
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5637468 |
Salt stabilization of antibody-enzyme conjugates heat-dried into paper
New and useful methods of producing stabilized enzyme antibody conjugates are disclosed which are particularly useful in forming multi-layer immunoassay test devices. In particular, the invention...
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5635403 |
Sample containment card for air or station contamination monitoring system and process
A tracking and identification card for an air filter specimen, the card having a sheet-like base with a substantially flat support surface for supporting the specimen, the base having a...
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5632957 |
Molecular biological diagnostic systems including electrodes
A system for performing molecular biological diagnosis, analysis and multi-step and multiplex reactions utilizes a self-addressable, self-assembling microelectronic system for actively carrying out...
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5631163 |
Method for the determination of specific gravity of fluids
Disclosed are a method and device for the determination of specific gravity in aqueous systems, particularly urine. The invention improves upon the known systems for detecting specific gravity by...
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5628960 |
Composite cellulose nitrate membrane on polyester support
There is disclosed a composite isotropic cellulose nitrate membrane on a polyester support and a method of making the same, the membrane having particular utility as various types of...
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5624809 |
Device for immunochromatographic analysis
Methods are disclosed for conducting assays. One such method comprises providing in combination a first bibulous member zone ("first zone") and a liquid medium containing a component. The first...
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5622870 |
Device and method for completing a fluidic circuit
Disclosed are assay apparatus, devices and methods that permit longitudinal capillary flow of liquid between two pieces of bibulous material which, prior to actuation, are in a non-capillary flow...
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5621072 |
Purified guaiacum resin and method for making same
A purified guaiacum resin which is obtained by isolation from a natural guaiacum resin with chromatography using a gel for reversed chromatography as a stationary phase and a polar solvent as a...
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5620845 |
Immunoassay diagnostic kit
An immunoassay process is provided for the detection of a target antigen in a fluid sample where an admixture of the target antigen and a labeled capture reagent against the target antigen is...
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5620900 |
Means and method for the determination of ammonium ions
The invention relates to an absorptive support and a method for the determination of ammonium ions in aqueous solutions by the Berthelot method using one absorptive support. The absorptive support...
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5620656 |
Packaging systems for peracid sterilization processes
Devices useful to monitor whether or not an article has been exposed to sterilizing conditions are provided and comprise a package and an indicator associated with the package. The package is...
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5620860 |
Method for washing immunoassay elements
A method of dispensing wash solution to separate free from bound labels in a slide immunorate assay. The method comprises dispensing wash first as separate drops spaced to allow complete absorption...
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5620901 |
Determination of concentration by affinity titration
A method for determining the amount of analyte in a sample utilizes a series of test regions with systematically varied, preferably monotonically increasing, affinity for a specific binding partner...
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5618701 |
Method of processing nucleic acid samples
A method of processing nucleic acid samples for analysis comprises the use of one or more manifolds (10) with a plurality of individual solid phase members (11) adapted for cooperation with a...
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5612178 |
Method of quantitative enzyme determination
Methods and kits are provided for the quantitative determination of the presence of an enzyme analyte in a sample by determination of the rate of analyte catalyzed reaction on a chromatographic...
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5612222 |
In vitro test for dermal corrosive properties
Methods and a device for determining the corrosivity of a substance to human skin or membrane are disclosed. In one approach, corrosivity is evaluated by measuring the time required for the test...
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5610073 |
Use of CO.sub.2 absorbant for stabilization of dried alkaline reagent in creatinine assay
Disclosed is an improvement to the method for the detection of creatinine in which creatinine, in aqueous solution, is contacted with a dry reagent system of an indicator for creatinine. The assay...
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5610072 |
Detection of caffeine in beverages
The caffeine content of a beverage is measured by inserting a dipstick into the beverage. The dipstick is impregnated with a reagent that changes color when reacted with caffeine. The degree of...
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5607863 |
Barrier-controlled assay device
An assay device for detection and/or determination of an analyte in a test sample uses a barrier containing an aperture to control the application of reagents to the device for greater...
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5605662 |
Active programmable electronic devices for molecular biological analysis and diagnostics
A self-addressable, self-assembling microelectronic device is designed and fabricated to actively carry out and control multi-step and multiplex molecular biological reactions in microscopic...
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5604110 |
Binding assay device
A device for performing an enzyme-labelled binding assay comprises an absorbent material and a developing solution, wherein the absorbent material is provided with a plurality of reagent zones...
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5603898 |
Dry-type analytical element for immunoassay
A dry-type analytical element for immunoassay having at least one water-permeable layer for measuring a ligand in a sample according to enzyme immunoassay, which comprises, (A) a water-soluble...
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5601995 |
Apparatus and method for detecting coagulation in blood samples
The method and apparatus are useful for determining a propensity of a blood sample to change from a liquid state to a coagulated state and additionally for measuring the propensity of a coagulated...
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5601986 |
Assays and devices for the detection of extrahepatic biliary atresia
The present invention involves a variety of assay methods and devices for screening or diagnosing the occurrence of extrahepatic biliary atresia. In particular the methods and devices involve an...
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5597700 |
Method for detecting free insulin-like growth-factor-binding protein 1 and a test device for detecting the ruptures of fetal membranes using the above method
A method and device for detecting fetal membrane rupture by detecting only that insulin-like growth-factor-binding protein 1 (IGFBP-1) which is free of insulin-like growth factors 1 and 2 (IGF-1...
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5597532 |
Apparatus for determining substances contained in a body fluid
An apparatus for the optoelectronic evaluation of test paper strips for use in the detection of certain analytes in blood or other body fluids. The test strip comprises an elongated plastic part...
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5593895 |
Method for the detection of protein in urine
Disclosed is an test for the detection of protein in urine by the use of a reagent system containing a buffer and a protein error indicator. The method involves the use of tartaric acid as cation...
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5593638 |
Apparatus for estimating the change in an analyte from hemolysis in a fluid sample
The present invention concerns a method of detecting hemolysis in a whole-blood sample, a method of determining an elevation in the potassium ion concentration of a whole-blood sample, an apparatus...
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5589347 |
Multilayer analysis elements for the determination of total cholesterol
A multilayer analysis element for determination of total cholesterol is prepared having a light-transmissive water-impermeable support, at least one hydrophilic polymer layer on said support and a...
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5583047 |
Method of detecting the permeability of an object to oxygen
A method of detecting the permeability of an article to oxygen is disclosed. A fluorescent redox indicator, preferably riboflavin, is dispersed in a carrier and placed on an impermeable substrate....
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5578577 |
Method for storing labile proteins
The present invention relates to improved specific binding assay methods, kits and devices utilizing chromatographically mobile specific binding reagents labelled with colloidal particles. Specific...
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5573921 |
Immunochemical displacement for determining an analyte
The present invention pertains to a process for determining an analyte, especially a low-molecular-weight pollutant in a sample. It is carried out by partially dipping into the sample a test strip,...
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5571948 |
Pressurized air tank air quality tester
A pressurized air tank air quality tester comprising a housing having a longitudinal bore disposed therein. The housing has at least one closure disposed on at least one of the ends of the housing...
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5571667 |
Elongated membrane flow-through diagnostic device and method
An apparatus is provided for use in assays for the detection of a bindable target substance in a liquid sample. The apparatus comprises an elongate reaction membrane strip which is porous and...
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5569608 |
Quantitative detection of analytes on immunochromatographic strips
A method for determining the concentration of analyte in a test fluid by immunochromatography techniques which involves quantitatively determining the signals from captured analyte/labeled binding...
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5565170 |
Multilayer analytical element for assaying fructosamine
A multilayer analytical element for assaying fructosamine having a liquid-impermeable support, a dried buffer-containing layer which contains a buffer having pH of 8 to 12 formed on the support,...
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5565363 |
Reagent composition for measuring ionic strength or specific gravity of aqueous solution samples
A reagent composition comprising (a) one or more pH buffers, (b) one or more pH indicators, and (c) one or more surfactants as a sensitizer, is suitable for measuring ionic strength or specific...
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5563042 |
Whole blood glucose test strip
A whole blood glucose test strip for measuring glucose in an unmeasured whole blood sample which does not require removal of excess sample, and which is adapted for use in a reflectance reading...
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5563031 |
Highly stable oxidative coupling dye for spectrophotometric determination of analytes
A dye couple compound is provided for use in a test device containing a reagent system for detecting the presence or quantity of an analyte in a sample. The reagent system comprises one or more...
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5563040 |
Method and apparatus for immunological diagnosis of fungal decay in wood
A method and apparatus for detecting incipient fungal decay in wood is described. Anti-xylanase monoclonal antibody is immobilized in a defined capture zone to a polyester assay substrate....
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5563073 |
Personal blood alcohol level testing kit
A personal blood alcohol level testing kit utilizing alcohol-sensitive pads which are stored in a package that permits the storage of the alcohol-sensitive pads within its interior without exposing...
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5561045 |
Detection reagent, article, and immunoassay method
The binding site on an immunoglobulin for a protein is blocked by hydrophobically coupling the immunoglobulin to a blocking agent such as a label. This results in a detection reagent useful in a...
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