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6197598 |
Devices and methods for separating cellular components of blood from liquid portion of blood
A device for the separation of the liquid portion of blood from the cellular components of blood comprises: (1) a pad of porous material permeable to the liquid portion of blood but capable of...
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6194224 |
Diagnostic membrane containing fatty acid sarcosinate surfactant for testing oral fluid
A diagnostic test strip for determining the presence of a specified analyte in a fluid sample is described. The test strip has a test membrane sandwiched between two layers of a plastic sheath. The...
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6194221 |
Hybrid one-step immunochromatographic device and method of use
This invention relates to a lateral flow immunochromatographic assay device with an increased range of sensitivity without an increase in the clearance time or the occurrence of false positive...
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6194225 |
Immunochromatography-assisted device
An immunochromatography-assisted device is disclosed which facilitates accurate and rapid detection of an antigen contained in a fluid sample and from which background coloring and blank coloring...
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6194160 |
Systems and methods for rapid blot screening
Systems and methods for processing membrane flow-through assays to provide more rapid testing. The systems include a plate for receiving a cartridge having a membrane which, for example, can be a...
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6194222 |
Methods for monitoring the status of assays and immunoassays
The invention relates in part to the use of independent assay controls (IACs) for the optical communication between an assay device and an instrument in monitoring and performing assays, preferably...
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6190918 |
Analyte detection device and process
The present invention provides a device and a process for detecting an analyte in a biological fluid. The device comprises a separating matrix for separating analyte from the fluid and means for...
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6187268 |
Transparent flow through membrane for dry reagent analytical devices
Disclosed is a diagnostic device for the colorimetric detection of an analyte in a test fluid. The device is a dry reagent layer which is overcoated with a transparent, fluid permeable membrane....
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6180417 |
Immunochromatographic assay
Disclosed is a device and method for carrying out an assay for an analyte in a fluid test sample by immunochromatography. The device involves a strip having a non-porous receiving member of a...
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6171866 |
Luminescence indicator for determining calcium ions
The invention relates to a compound having the general Formula I: ##STR1## including its salts, where Z is either the group having the general Formula II: ##STR2## where R 1 is alkyl having 1-4...
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6168956 |
Multiple component chromatographic assay device
An assay device for the performance of immunochromatographic assays and other assays has two principal parts, a first opposable component and a second opposable component. The first opposable...
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6168957 |
Diagnostic test strip having on-strip calibration
A dry phase reagent test strip for measuring the concentration of an analyte in a biological fluid includes a colored indicator whose hue indicates a calibration of the strip. Preferably, the test...
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6163026 |
Chemically stabilized light selective element for imaging applications
An imaging system having an imaging sensor providing sensor signals in response to incident light and control signals, control circuitry configured to generate control signals for controlling said...
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6162398 |
Assay device using shrink wrap
Devices for conducting an assay are disclosed which utilize shrink wrap as a casing material. The use of shrink wrap casings enables the preliminary fluid filtering step and the chemical detection...
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6162646 |
Urine pH indicator system and associated methods
A urine pH indicator has a plurality of hydrophilic, non-ionic, polymer foam carrier particles. The carrier particles are impregnated with an indicator complex having more than one chromophore and...
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6159745 |
Interdigitated electrode arrays for liposome-enhanced immunoassay and test device
A test device for detecting or quantifying determining an analyte in a test solution includes an absorbent material having contact, liposome lysing and electrochemical measurement portions. The...
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6159747 |
Analytical test element with a blister filled with liquid
The invention concerns an analytical test element containing an absorbent material with a sample application and detection zone and a blister filled with liquid on a support, wherein the support...
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6156272 |
Method and apparatus for urine self-test intended for use in a toilet
A method and apparatus for urine self testing wherein the apparatus is placed directly into the toilet after urination which avoids the direct placement and retention of an apparatus in the stream...
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6149863 |
Method of steam sterilization using a steam sterilization indicator
A steam-sensitive ink comprises, as active ingredient, a tetrazolium salt. The ink may be coated on, or impregnated into, a substrate to form a steam sterilization indicator.
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6149865 |
Test strips for the determination of the ionic strength or specific gravity of an aqueous sample
The ionic strength or the specific gravity of an aqueous test sample is determined by mixing the sample with a reagent composition on a test strip. The strip includes a bibulous carrier containing...
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6146589 |
Assay device for detecting the presence of an analyte involving sequential delivery of reagents through a liquid circuit
An assay device for detecting the presence of an analyte in a sample, wherein a visible signal indicative of the presence or absence of said analyte is produced at a detection site on a support,...
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6146591 |
Biochemical detection system for rapid determination of the presence of toxins, bacteria, and other substances
This device discloses a portable sequential contaminant detection system which can test samples for contaminants at predetermined timed intervals. The detection system has a motor to advance a...
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6143576 |
Non-porous diagnostic devices for the controlled movement of reagents
The assay devices, assay systems and device components of this invention comprise at least two opposing surfaces disposed a capillary distance apart, at least one of which is capable of...
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6140134 |
Analyte detection with a gradient lateral flow device
A method of determining the concentration of an analyte in a sample, said method comprising bringing said analyte in contact with an indicator zone comprising a concentration gradient of a mobile...
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6140062 |
Method of determining the heparin content
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6140136 |
Analytical test device and method of use
The present invention provides an analytical test device for conducting assays of biological fluids. Methods for carrying out the assays with the disclosed analytical test device are also provided.
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6136551 |
Assay for detecting the presence of botulinum toxin neutralizing antibodies in a patient serum sample
An assay for the identification of neutralizing botulinum antibodies in sera is provided which includes the steps of separating non-sodium dodecyl sulfate, non-trypsinized complex botulinum toxin...
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6132975 |
Method of collecting markers of bone metabolism from sweat
The invention disclosed herein relates to a method of monitoring bone metabolism comprising continuously collecting a sweat sample from a subject and assaying the sweat sample to determine the...
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6130100 |
Manufacture of test strips
A process of manufacturing test strips of the type comprising a length of porous carrier material capable of acting as a liquid flow path for a sample liquid and having at least zone downstream...
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6126900 |
Graphite nonwovens as functional layers in diagnostic test kits
The present invention relates to the use of graphite nonwovens and graphite woven fabrics for removing cellular constituents from blood and corresponding test agents for analysis of blood...
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6121008 |
Chromatographic immunoassay device and method utilizing particle valency for quantification
A method and device are provided for the semi-quantitative and quantitative determination of an analyte in a sample. A non-competitive trap which can bind unreacted labelled receptor to analyte but...
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6121050 |
Analyte detection systems
The present invention is directed to an improved analyte systems which are able to compensate for interfering signals and to provide accurate detection and/or quantification of analytes in a...
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6117685 |
Ozone indicator and ozone detecting ink
The invention provides a method of detecting ozone expediently and with high sensitivity. The invention, therefore, is directed to an ozone indicator comprising (1) at least one color-change layer...
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6114170 |
Reagent for determining the ionic strength and/or the specific weight of aqueous liquids and method
The invention relates to a method for determining the ionic strength and/or the specific weight of aqueous liquids and a reagent for this purpose, the composition of the reagent being such that the...
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6107100 |
Compounds and methods for determination of thiols
Compositions and methods are provided for determining thiols or disulphides in which a sulfur containing analyte is combined with a thiol-specific reagent to produce an intermediate, and the...
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6106732 |
Integral blood plasma or serum isolation, metering and transport device
A process for separating plasma or serum from mammalian whole blood includes the steps of applying a sample of blood through a hydrophobically faced sample receiving hole positioned in a first...
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6107083 |
Optical oxidative enzyme-based sensors
The invention discloses enzyme-based optical sensors for detecting blood components which are substrates for oxidative enzymes, the sensors advantageously employing a multiple-layer structure...
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6100099 |
Test strip having a diagonal array of capture spots
The invention relates to multiplex ligase chain reaction (LCR). Two or more putative target sequences are selected. For each one, a set of four probes is used simultaneously to amplify the putative...
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6099802 |
Hollow frustum reagent test device
A hollow, frustum-shaped disposable device is used in an apparatus for measuring the concentration of an analyte in a sample of a biological fluid. The smaller end of the frustum has a porous...
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6096268 |
Chromogenic and turbidimetric assay device
The present invention relates to a diagnostic assay device comprising a fluorophore element comprising a fluorophore imbedded therein, and a reagent element. The fluorophore element and reagent...
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6090936 |
Device for isolating nucleic acids
Device for the isolation of nucleic acids from a liquid sample by introducing the liquid into the device through an inlet opening and passage of the sample through a nucleic acid binding material...
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6087185 |
Integrated packaging holder device for immunochromatographic assays in flow-through or dipstick formats
The prevent invention relates to an integrated package-holder assay devices for detecting the presence of analyte in a sample. The device serves the dual roles of supporting and protecting an...
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6087184 |
Opposable-element chromatographic assay device for detection of analytes
An assay device for detection or determination of an analyte in a sample uses opposable components and is suitable for assay of human chorionic gonadotropin and other protein or glycoprotein...
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6083460 |
Component measuring apparatus and component collecting apparatus
A liquid specimen collection device includes a main body provided with a passage extending between opposite ends of the main body that defines a capillary tube liquid specimen flow path. One end of...
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6077711 |
Frangible ampule specimen test card
A method and apparatus for testing tissue samples is provided which includes an integrated specimen test card. The test card is especially useful in testing for the presence of blood in stool...
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6074881 |
Method for the prevention of hemoglobin interference in reagent systems for measuring peroxidase activity
The present invention involves an improvement to an assay for the activity of a metal chelate, such as copper II/creatinine, which activity is related to the concentration of the analyte in a fluid...
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6066504 |
Coagulation or lysis assays using an electroactive species
The present invention provides a single-use electronic device and test card for use therein which performs a coagulation or lysis assay of a blood sample. The device includes a housing having an...
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6063337 |
Test strip for measuring device for optically detecting the concentration of a substance in a body fluid
In a test strip for use with a measuring device for determining the concentration of a substance in a body fluid by means of an optical measuring system using a beam of light directed onto a...
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6060023 |
Molecular sensing apparatus
A molecular sensing apparatus comprises a first electrode (10), a second electrode (12), a first molecule (20), a second molecule (22), and a third molecule (34). The first molecule (20) has a...
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6060266 |
Self-contained incubator for growth of microorganism
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