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6335205 |
Method and test strip for determining an analyte
The invention concerns a method for the immunological determination of an analyte on a chromatographic test strip containing one or several absorbent matrices on a carrier material which are in...
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6328931 |
Analyte collection and assaying assembly
Swabbing and assaying structures, and selected methods of use, enable a test surface to be swabbed, and subsequently facilitate a quantitative determination of the quantities of analyte collected...
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6326214 |
Immunity testing device
An immunity testing device formed of a thin sheet of material folded to three portions, and the two end portions; named "front cover"0 and "back cover"; fold back to different sides of the center...
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6322750 |
Gas detector indicator strip providing enhanced dynamic range
The present disclosure is a tape responsive to gases. One version is paper impregnated with lead acetate, a backing layer of impervious sheet material, and a top face pervious, transparent layer....
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6322992 |
Method for the determination of a specific binding ligand using a vanadium bromoperoxidase as a signal-generating enzyme
An analytical element can be used to sensitively and rapidly detect a wide variety of specific binding ligands in either a competitive or sandwich assay format. The assays are carried out using a...
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6319466 |
Test device for detecting the presence of a residue analyte in a sample
A test device for detecting the presence of a residue analyte in a sample includes a support strip and a sample-absorbing matrix attached to the support strip. The sample-absorbing matrix has a...
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6319665 |
Home test kit and method with telephone verification of results
Self-testing for a disease or physiological condition is achieved by having the individual being tested obtain a sample of physiological fluid, e.g., blood, urine, sputum or saliva, from him or...
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6316264 |
Test strip for the assay of an analyte in a liquid sample
An improved test strip for determining the presence or concentration of unknown or a constituent in a liquid test sample is disclosed. The test strip comprises a support strip and a test pad,...
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6309887 |
Filter paper treatment for improved diagnostic assays
Filter paper absorbed with a solution of anticoagulant, e.g., ethylene diamine tetra-acetic acid (EDTA), then dried, useful for collection of a blood sample for analysis of hemoglobin or a...
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6306665 |
Covalent bonding of molecules to an activated solid phase material
Microporous solid phase materials that are suitable for lateral flow and other assays for detecting the presence of analytes in test samples, that are stable under variations in humidity and, even...
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6303389 |
Rapid flow-through binding assay apparatus and method therefor
The invention includes assay cassettes that can be employed during rapid flow-through binding assays. The assay cassettes can be disposable units suitable for one-time use and readily assembled to...
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6303288 |
Integrated microchip genetic testing system
A genetic testing system includes a miniaturized thermal cycling device and an integrated, unitary microchip based detection device with microfluidic controls, on chip electronics. The genetic...
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6303385 |
Fluorescent N-alkylated acrylamide copolymers and optical pH sensors
A water-insoluble copolymer which is composed of (a) from 39.9 to 60% by weight of N,N-dimethylacrylamide or N,N-dimethylmethacrylamide; (b) from 60 to 39.9% by weight of N-alkylated acryl amides...
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6299838 |
Test apparatus for assaying a component in a liquid sample
A test apparatus for assaying a component in a liquid sample by measuring a reflected light, comprising a support having a through hole or a light permeable area, a reagent layer having a detecting...
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6297060 |
Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network
Devices for use in heterogeneous ligand-receptor assays, having a porous member in contact with a nonabsorbent textured surface, where the surface texturing is such that a capillary network is...
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6291249 |
Method using an apparatus for separation of biological fluids
A cell containing sample is separated into a cell containing portion and a substantially cell depleted portion, by mixing the sample with particles to produce a cell containing network, and...
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6287867 |
Asymmetric porous membranes
The invention concerns the use of an asymmetric porous membrane for the evenly distributed concentration of a substance which is not or not substantially adsorbed to the membrane and which is...
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6284198 |
Self appearing warning sign device and method of manufacture
A self-appearing warning sign device and method for the manufacture of a self-appearing warning sign device including a relatively thin gas impermeable support member upon which a coating is...
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6280687 |
Diagnostic method for detection of periodontitis or peri-implantitis
The invention relates to methods and test kits for diagnosis of periodontal disease activity in mammals, especially in human. The methods of the invention provide for rapid chair-side diagnosis of...
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6281004 |
Quality control for cytochemical assays
The invention describes quality control devices for assays that measure analytes in cells and tissue samples, and methods of use thereof. In particular, the quality control device comprises a...
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6277653 |
Optical assaying method and system having movable sensor with multiple sensing regions
An optical assaying method and system having a movable sensor is described. In one aspect, the present invention is a sensing system having a rotating sensor disk coated with indicator dyes...
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6277650 |
Analyte assaying device
The invention is an improved single-step test device for detecting the presence of a pre-selected analyte in a urine stream. The device includes a hollow rectangular outer casing and an assay...
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6274326 |
Method and apparatus for detecting proper strip insertion into an optical reflectance meter
A method and apparatus for detecting proper strip insertion into an optical reflectance meter. An electrical or electromagnetic device within the optical reflectance meter launches a signal when a...
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6267242 |
Chemical indicator sheets and packaging bags for sterilization made with the use of the same
This invention provides a sheet which has a chemical indicator, in particular, a composition layer for use as an indicator in hydrogen peroxide plasma sterilization, and further provides a...
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6265176 |
Dot immunoassay on plastic sheets
Analytical test kits and assay procedure employs test cards or strips of an inert plastic carrier having a flat, non-absorbent surface, containing thereon spots of insolubilized reagent for the...
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6258548 |
Single or multiple analyte semi-quantitative/quantitative rapid diagnostic lateral flow test system for large molecules
Lateral flow device and method are provided for performing semi-quantitative visual or instrument-based detection in a test sample of a large molecule analyte that contains two binding domains, α...
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6255117 |
Method and device for determining monopersulfate
A test method and device are described for quantitatively determining the presence and concentration of monopersulfate ion in aqueous solution. Contacting the aqueous solution containing...
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6251601 |
Simultaneous measurement of gene expression and genomic abnormalities using nucleic acid microarrays
The invention comprises a multi-color, comparative hybridization assay method using an array of nucleic acid target elements attached to a solid support for the simultaneous detection of both gene...
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6248596 |
Liposome-enhanced immunoassay and test device
A test device for detecting or determining an analyte in a test solution includes an absorbent material having separate contact, competitive binding, and measurement portions. The contact portion...
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6248598 |
Immunoassay that provides for both collection of saliva and assay of saliva for one or more analytes with visual readout
A device that provides for both the collection of saliva and detection of at least one analyte therein, e.g., a drug, is provided. This device provides for rapid analysis of saliva samples, while...
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6245574 |
Sensors
Sensors for the qualitative and quantitative determination of K + ions in aqueous systems are described, which consist essentially of a carrier and an active layer applied to this carrier, whereby...
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6242267 |
Oscillation apparatus and methods for multi-analyte homogeneous fluoro-immunoassays
An apparatus and method for rapidly analyzing samples for analytes of interest by an homogeneous immunofluorescence assay. The apparatus includes a sample test cartridge having a high control...
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6242265 |
Use of doubly or triply charged cations in immunochemical assays
The use of calcium salts, magnesium salts or combination thereof in immunochemical methods for the determination of an analyte in a sample. These salts increase the specificity of such...
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RE37194 |
High throughput solid phase chemical synthesis utilizing thin cylindrical reaction vessels useable for biological assay
A high throughput chemical synthesis system utilizing cylindrical reaction vessels is disclosed. Reaction vessels are utilized which include a tubular member adapted for placement of electronically...
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6235489 |
Method for diagnosing and distinguishing stroke and diagnostic devices for use therein
A method for determining whether a subject has had a stroke and, if so, the type of stroke which includes analyzing the subject's body fluid for at least four selected markers of stroke, namely,...
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6231811 |
Ceramic substrate and sensor element using the ceramic substrate
A ceramic substrate and a sensor element using the ceramic substrate. The ceramic substrate has a flat substrate in which an envelopment space is formed and a porous body disposed so as to cover...
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6224831 |
Microassay device and methods
The subject invention relates to a rapid, field-portable, modular, versatile and highly reliable assay device for substances, particularly drugs of abuse, which provides a positive signal in the...
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6221625 |
Enzyme-labeled immunoassay and device therefor
An enzyme-labeled immunoassay is performed by the steps of allowing a test sample to react with an enzyme-labeled reagent, allowing a substrate to react with the enzyme to form a signal, and...
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6218134 |
Process for specific binding assay for measuring the amount of analyte in a liquid test sample
A specific binding assay process which is useful for quick qualitative or quantitative measurement and which can be used for various purposes, and a specific binding assay device suitable for the...
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6218116 |
Method and device for treatment by complexing of a liquid medium
A method for determining the presence, in a liquid medium, of a plurality of different nucleic ligands in the free state comprises: (a) providing a support for plural complexing on which are...
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6217744 |
Devices for testing fluid
An improvement is described to disposable devices for performing chemical or biological tests on a sample of fluid, and the method by which such devices perform tests. The power for the device...
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6217827 |
Hydride gas detecting tape
A substrate such as a porous tape coated with an adsorbent and impregnated with a processing solution which includes a silver salt, an organic acid such as benzenetricarboxylic acid or...
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6214570 |
Method for separating non-HDLs from HDLs, and determining, HDL cholesterol
The subject matter of the application is a method for the separation of non-HDL lipoproteins from biological fluids in a carrier through which liquids can flow. The carrier contains a precipitating...
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6210898 |
Method of performing immunochromatography
The invention relates to multiplex ligase chain reaction (LCR). Two or more putative target sequences are selected. For each one, a set of four probes is used simultaneously to amplify the putative...
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6210971 |
Assay for the detection of creatinine
Disclosed is an improved method for the detection of creatinine in a fluid test sample by contacting the test sample with cupric ions, a hydroperoxide, citrate and an oxidizable dye which gives a...
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6200817 |
PH and amine test elements and applications to diagnosis of vaginal infections
Tests for elevated pH and volatile amines in aqueous fluids are disclosed, including tests useful in the diagnosis of bacterial vaginosis and in other biological conditions. By using formulated...
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6197494 |
Apparatus for performing assays on liquid samples accurately, rapidly and simply
An element and method for easily performing liquid assays are disclosed. The element uses capillary action to draw a predetermined volume of a liquid sample into a reaction chamber charged with...
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6197598 |
Devices and methods for separating cellular components of blood from liquid portion of blood
A device for the separation of the liquid portion of blood from the cellular components of blood comprises: (1) a pad of porous material permeable to the liquid portion of blood but capable of...
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6194224 |
Diagnostic membrane containing fatty acid sarcosinate surfactant for testing oral fluid
A diagnostic test strip for determining the presence of a specified analyte in a fluid sample is described. The test strip has a test membrane sandwiched between two layers of a plastic sheath. The...
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6194221 |
Hybrid one-step immunochromatographic device and method of use
This invention relates to a lateral flow immunochromatographic assay device with an increased range of sensitivity without an increase in the clearance time or the occurrence of false positive...
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