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8178045 |
Interchangeable preconcentrator connector assembly
An interchangeable preconcentrator assembly comprises an outer housing and an inner housing defining a chamber. A biased urging member is held at least partially within the outer housing and...
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8163535 |
Devices and processes for nucleic acid extraction
Devices, processes, and kits for the extraction of nucleic acids from biological samples are disclosed. The devices comprise a first port, a second port, and a binding chamber intermediate and in...
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8163184 |
Apparatus and method for separating and concentrating fluids containing multiple components
An apparatus is disclosed that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the...
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8163183 |
Magnetic particle parallel processing apparatus permitting repeated use of container and method of magnetic particle parallel processing permitting repeated use of container
To provide a magnetic particle parallel processing apparatus permitting repeated use of a container, and a method of magnetic particle parallel processing permitting repeated use of a container,...
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8147773 |
Method and apparatus for modifying pressure within a fluid dispenser
A fluid dispenser useful in automated biological reaction systems comprising a barrel having a reservoir chamber, the barrel having an upper portion and a lower portion, a cap located on top of the...
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8148168 |
Method and device for sample preparation
The invention provides extraction columns for the purification of an analyte (e.g., a biological macromolecule, such as a peptide, protein or nucleic acid) from a sample solution, as well as...
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8124032 |
Microfluidic device and method of using same
The invention relates to a microfluidic device comprising one or more fluid channels, one or more fluid ports, and a V-shaped particle retention structure. The fluid channel is generally opposite...
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8114680 |
Buffy coat separator float system and method
A tube and float system for use in separation and axial expansion of the buffy coat includes a transparent or semi-transparent, flexible sample tube and a rigid separator float having a specific...
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8088285 |
Device for mixing and separation of magnetic particles
An apparatus for mixing and separating magnetic particles in a liquid comprises a holder having a plurality of apertures configured as an array of rows and columns and a plurality of containers...
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8084272 |
Amelioration of heterophile antibody immunosensor interference
The invention is directed to methods and devices for reducing interference from heterophile antibodies in an analyte immunoassay. In one embodiment, the invention is to a method comprising the...
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8080202 |
Component separating device and chemical analysis device using the same
A vibrator has a large strength of a standing wave even with a low driving voltage, thereby improving the accuracy of component separation. A device according to the present invention includes a...
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8075778 |
Fluid separation
A method of separating a first fluid from a second fluid may include prewetting with the first fluid at least one channel defined by a separation device, the at least one channel thereby containing...
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8071054 |
Microfluidic magnetophoretic device and methods for using the same
A microfluidic device may employ one or more sorting stations for separating target species from other species in a sample. The separation is driven by magnetophoresis. A sorting station generally...
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8048320 |
Method and apparatus for collecting biological materials
A method and apparatus for separating and concentrating a selected component from a multi-component material. The multi-component material may include a whole sample such as adipose tissue, whole...
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8048321 |
Apparatus and method for separating and concentrating fluids containing multiple components
An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It...
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8043858 |
Dynamic desalter simulator
A small-scale dynamic simulator for crude oil refinery desalters has a pressurized oil deviblis configured to hold a supply of crude oil and a water deviblis configured to hold a supply of wash...
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8034628 |
Apparatus and method for trapping bead based reagents within microfluidic analysis systems
An on-chip packed reactor bed design is disclosed that allows for an effective exchange of packing materials such as beads at a miniaturized level. Also disclosed is a method of treating a sample...
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8017379 |
Nucleic acid purification instrument
According to this invention, a nucleic acid purification instrument whereby it is possible to prevent dispersion of a mist thai causes contamination upon discharge of a solution is realized. A...
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8017091 |
Beadwhacker
A device consisting of a low-RPM motor wherein the motor spins a flat disk, a peg is attached to the disk, a stationary spring armature wherein the peg can activate the stationary spring armature...
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7988935 |
Handheld and portable microfluidic device to automatically prepare nucleic acids for analysis
A handheld and portable extraction device is directed to a microfluidic-based system to be used in the field to extract and purify an analyte, preferably a nucleic acid, from a fluid-based sample....
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7985385 |
Nanoscale array biomolecular bond enhancer device
The invention teaches the use of an addressable nanoscale device to create a programmable substrate useful in selectively attracting proteins, nucleating protein crystals and growing protein...
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7985386 |
Implantable medical device for diagnostic sensing
An implantable medical device is provided for use with an external detector to detect an analyte in vivo. In one embodiment, the device consisting essentially of a substrate; a plurality of...
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7972578 |
Device and method for separating components of a fluid sample
A device and method is provided for separating heavier and lighter fractions of a fluid sample. The device includes a plurality of constituents comprising a container and a composite element in the...
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7972516 |
Device and method for separating, mixing and concentrating magnetic particles with a fluid and use thereof in purification methods
A process for manipulating magnetic particles suspended in a fluid that are able to bind to an entity of interest, the fluid being contained in a reaction vessel having a large funnel shaped upper...
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7964411 |
Membrane based concentrators
A sample concentrator for concentrating analytes in a solvent-containing liquid sample stream, including concentrator housing having a sample stream flow channel and a gas stream flow channel...
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7947236 |
Device for separating components of a fluid sample
A device for separating heavier and lighter fractions of a fluid sample is provided, the device including a container and a unitary separator located therein, the separator having an overall...
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7947186 |
Centrifugal device and method for fluid component separation
A rotor is provided for the centrifugal separation of a composite fluid, such as animal or human blood, into components. An inner surface of the rotor includes at least one hydrophobic area having...
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7943386 |
Apparatus and method for determining the volume fractions of the phases in a suspension
An apparatus for determining the volume fractions of the phases in a suspension includes a body, a channel structure, which is formed in the body, and an inlet area and a blind channel, which is...
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7939035 |
Sample preparation device for extracting drug residue
The present invention provides a sample preparation device for extracting drug residue. It comprises a case, in which a water bath, a vortex mixer, and a homogenizer are integrated. The case also...
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RE42315 |
Nanostructured separation and analysis devices for biological membranes
The present invention provides a nanostructured device comprising a substrate including nanotroughs therein; and a lipid bilayer suspended on or supported in the substrate. A separation method is...
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7927495 |
Separation and cleaning of a suspension comprising magnetic microparticles
A device (10) is described for automatically separating solid and liquid phases of a suspension (78) and for purifying magnetic microparticles (76) loaded with organic, e.g., biological or...
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7919049 |
Buffy Coat separator float system and method
A tube and float system for use in separation and axial expansion of the buffy coat includes a transparent or semi-transparent, flexible sample tube and a rigid separator float having a specific...
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7867453 |
Gravity-driven fraction separator and method thereof
The present invention relates to a gravity-driven fraction separator and method thereof. The gravity-driven fraction separator is substantially a substrate having a microchannel structure arranged...
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7846394 |
Apparatus and method for separating particles within a specimen
Embodiments of the present invention provide an apparatus and a method for separating particles within a sample. The apparatus includes a reservoir for receiving a biological specimen therein,...
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7829026 |
Magnetic separation device
A magnetic separation device, comprising: at least a test tube base, for receiving at least a test tube; and a magnetic member, pivotally connected to the at least one test tube base and capable of...
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7806276 |
Buoy suspension fractionation system
A separator that uses centrifugation to fractionate a suspension such as blood comprises a separation container and a buoy. The buoy is carried in the separation container and has a tuned density...
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7776221 |
Device and method for separating magnetic or magnetizable particles from a liquid
A device is provided to separate magnetic or magnetizable particles from a liquid by using a magnetic field. The device includes two limbs made of a soft-magnetic material. An air gap is provided...
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7776273 |
Laser capture microdissection (LCM) extraction device and device carrier, and method for post-LCM fluid processing
The present invention generally discloses an extraction system that provides a locale for fluid processing and extraction on a post-microcapture transfer film. The extraction system includes a...
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7749531 |
Apparatus and method for detecting bacterial growth beneath a wound dressing
An apparatus and method are provided for visually monitoring, detecting, and/or determining the presence, absence, and/or growth of harmful or potentially harmful bacterial microorganisms beneath a...
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7745106 |
Methods and devices for separating liquid components
Methods and devices for preparing a solid-fibrin web are provided. One method may include drawing blood from a patient, separating plasma from the blood, contacting the plasma with a...
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7740805 |
Integrated CMOS-compatible biochip
A device for analyzing a fluid sample is provided. The device includes a substrate, a trench formed in said substrate, and a processor. The trench includes a channel, a sample chamber, and a...
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7727475 |
Micro chemical apparatus
In a micro chemical apparatus, guide walls as physical barriers are provided at a region where fluid A and fluid B as unmixed raw materials and a product are discharged so that, when the fluid A...
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7727727 |
Pretreatment method for extraction of nucleic acid from biological samples and kits therefor
The present invention relates to methods for pretreating biological samples for extraction of nucleic acid therefrom. The present invention employs a combination of at least one protein denaturant...
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7718129 |
Bioassay substrate and bioassay device and method
A bioassay substrate (1) takes a flat-plate shape in which the principal surface similar to that of optical disc such as CD, etc. is circular. At the center of the substrate (1), there is formed a...
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7718135 |
Sample holder for holding and transporting a sample vial within an NMR apparatus and automatic supply device for the automated exchange of NMR sample vials and method of operation thereof
A sample holder for fixing and transporting a sample vial (1) within an NMR configuration comprising an outer shell (4) and a continuous hollow space disposed inside the outer shell (4) and...
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7670563 |
Centrifuge and a support for use in a centrifuge
A centrifuge has a bucket for receiving the product to be centrifuged, and a support which is configured to be inserted in the bucket and receive microtiter plates and the like. The support has...
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7662630 |
Method for verifying the integrity of thermal desorption sampling tubes
An analyte of a sample is transferred to an analytical instrument by introducing a quantity of a compound of a standard material into a vessel containing an adsorbent material; introducing a...
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7608224 |
Stack of supports, in particular for cryopreservation of biological samples
Substrates (100) are described for receiving a plurality of samples, especially for the preservation of biological samples at cryotemperatures comprising a plurality of substrate plates (11, 12,...
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7560243 |
White blood cell functional assay
A method of rapidly assaying nucleotide receptor P2X7 pore activity in white blood cells contained within a blood sample. A method according to the invention includes the steps of: (a) labeling the...
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7553413 |
Plasma concentrator device
A plasma concentrator of this invention having a concentrator chamber, concentrator gel beads, a filter, and an agitator. The agitator has agitator blades extending outwardly from the lower end....
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