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7615028 Extracorporeal blood treatment and system having reversible blood pumps  
An extracorporeal blood treatment system including: a blood circuit having a first blood passage coupled at a first end to a first end of a blood treatment device and a second blood passage coupled...
7531133 Use of nitric oxide gas in an extracorporeal circuitry to treat blood plasma  
A method of reducing pathogens in blood by exposure to a nitric oxide containing gas in an extracorporeal circuitry is provided. The method includes: obtaining blood from a mammal or a blood...
7520988 Cross-flow filter cassette  
An improved cross-flow filtration unit utilizing at least one two-ply membrane is disclosed that has a particular pore size relationship in the two membrane layers.
7498275 Artificial pulmonary capillary  
The present invention is directed to a photolytic cell, and to a photolytic artificial lung incorporating such a cell. The photolytic artificial lung converts water to oxygen for blood absorption,...
7488302 Device allowing serial use of clean and alternative blood filters during blood filtration  
A device that allows for serial (time) use of clean blood filters during the use of a heart lung machine. The device is comprised of a series of filters and a switching mechanism that allows the...
7455812 Method and apparatus for controlled reoxygenation  
A method and apparatus for performing coronary perfusion and cardiac reoxygenation that enables accurate control of oxygen levels in blood used for the coronary circulation. Deoxygenated blood and...
7435342 Dialysate regeneration system for portable human dialysis  
A dialysate regeneration chamber is provided. In one embodiment, the dialysate regeneration chamber may include a toxin trap configured to selectively trap toxins and repel select cations.
7431754 Artificial lung  
An artificial lung includes a housing, a tubular hollow fiber membrane bundle contained in the housing and providing a multiplicity of hollow fiber membranes having a gas exchange function, a gas...
7399717 Oxygen generation in whole blood by photolytic activation  
Apparatus and methods for photolytic oxygenation of whole blood.
7347849 Modular medical treatment replaceable component  
A first flow path is defined within a first panel that forms a part of an extracorporeal fluid circuit. A second flow path is defined within a second panel that also forms a part of the...
7198751 Disposable, integrated, extracorporeal blood circuit  
A disposable, integrated extracorporeal blood circuit employed during cardiopulmonary bypass surgery performs gas exchange, heat transfer, and microemboli filtering functions in a way as to...
7129082 Bio-reactor device  
The invention provides a bio-reactor device and a method of cultivating live cells. The device comprises a holder which contains a matrix of porous foam material in whose interior live cells are...
7122151 Membrane apparatus with enhanced mass transfer, heat transfer and pumping capabilities via active mixing  
A combination mass transfer and pump apparatus, which in a single step actively mixes a first mass and a second mass and simultaneously pumps one of the first mass and the second mass through the...
7067307 Bioartificial device for the storage, cultivation and/or multiplication of cells  
The bioartificial reactor has a reactor vessel. A cell culture chamber in the reactor, in particular for liver cells, is divided off from a flow chamber for a nutritive medium and from a flow...
6994824 Artificial cardiopulmonary circuit system  
To provide an artificial cardiopulmonary circuit system having high heat resistance and excellent blood compatibility. The artificial cardiopulmonary circuit system includes a hollow fiber membrane...
6949220 Artificial heart-lung apparatus  
An integrated, artificial heart-lung machine and method for performing extracorporeal blood oxygenation and circulation. The heart-lung machine is a single unit in which a cylindrical artificial...
6858146 Artificial liver apparatus and method  
Artificial liver devices and methods for using the devices to purify a biological fluid are disclosed. The methods include the use of living hepatocytes ( 23 ) which are either unattached or...
6821790 Methods and apparatus for separation of biological fluids  
A method of separating a cell-containing sample into a substantially cell-depleted portion, and a cell-containing portion comprising at least one of a stem cell, a lymphocyte, and a leukocyte...
6508983 Exchanger apparatus and method of manufacture  
An exchanger and method for manufacturing the same are disclosed. In one embodiment, the exchanger crimps a hollow fiber bundle along a length of a cylindrical case in at least two radial...
6503450 Integrated blood oxygenator and pump system  
Improvements to integrated blood pump/oxygenator having a rotating hollow fiber bundle assembly that both oxygenates and pumps blood are provided. An inner member arranged along a central axis of...
6503225 Device for removal of gas bubbles and dissolved gasses in liquid  
A device ( 10 ) for removal of gas bubbles and dissolves gasses from fluids delivered into a patient during medical procedures is disclosed. A housing ( 20 ) having a number of gas permeable hollow...
6495101 Hollow fiber membrane oxygenator  
A hollow fiber membrane oxygenator of external blood circulation type has a housing and a lot of porous hollow fiber membranes for gas transfer housed in the housing. In the oxygenator, blood flows...
6468472 Cleaning and decontaminating dialyzers by per-compound solutions  
A composition for cleaning and decontaminating medical devices such as dialyzers. A per-compound oxidant, for example, hydrogen peroxide (H 2 O 2 ) and/or peracetic acid, is mixed with a buffer...
6454999 Integrated blood pump and oxygenator system having extended blood flow path  
An integrated blood pump/oxygenator having a rotating hollow fiber bundle assembly that both oxygenates and pumps blood is provided that includes a plurality of partitions disposed within or about...
6454998 Blood circulation apparatus coupling device which improves biocompatibility of inner surfaces with treated blood  
A coupling is connectable to an access of a blood compartment. The compartment has at least one inner surface intended to be coated with at least one molecular layer of a substance soluble in an...
6428747 Integrated extracorporeal blood oxygenator, pump and heat exchanger system  
An integrated blood pump, oxygenator and heat exchanger is provided having a rotating hollow fiber bundle assembly. A plurality of vanes arranged along a central shaft of the device increase...
6409921 Integrally asymmetrical polyolefin membrane for gas exchange  
Process for producing hydrophobic polyolefinic membranes for gas exchange via thermally induced liquid-liquid phase separation is disclosed. A solution of at least one polyolefin in a solvent...
6395226 Alkoxysilane/alkysilane copolymer coating of medical devices  
A coating for microporous hollow fiber membrane blood oxygenators increases the resistance of the fibers to passage of blood plasma through the micropores. The coating comprises...
6379619 Artificial gut  
An artificial gut ( 100 ) comprises a first hollow fiber ( 203 ) having an inner surface ( 215 ) that is lined with at least a portion of a layer of one or more of a plurality of biological...
6379618 Integrated blood oxygenator and pump system having means for reducing microbubble generation  
Improvements to integrated blood pump/oxygenator having a rotating hollow fiber bundle assembly that both oxygenates and pumps blood are provided. A plurality of vanes arranged along a central...
6350411 Microporous hollow fiber blood oxygenator  
The present invention is to a process for blood oxygenation using a microporous fiber membrane. The use of the hollow fiber allows improvements in plasma break through results. The oxygenator...
6339108 Oxygenator membrane  
The invention relates to an oxygenator membrane based on organically modified silicic-acid polycondensates into a process for preparation thereof. The oxygenator membrane is obtainable by...
6331272 Method and membrane system for sterilizing and preserving liquids using carbon dioxide  
Microorganisms are destroyed and enzymes can be inactivated in liquids, such as juices for example, by continuously flowing the liquid and continuously flowing pressurized dense CO 2 along flow...
6312647 Method for enriching a fluid with oxygen  
A membrane oxygenator may receive a supply of pressurized oxygen and a supply of pressurized fluid, such as water or blood. In one example, a plurality of tubular membranes are disposed in a...
6291249 Method using an apparatus for separation of biological fluids  
A cell containing sample is separated into a cell containing portion and a substantially cell depleted portion, by mixing the sample with particles to produce a cell containing network, and...
RE37379 High pressure gas exchanger  
An apparatus 10 and method for delivering a high partial pressure of a gas into a liquid. The apparatus has a gas transfer device 12 with a housing 14 that includes upstream 16 and downstream 18...
6267926 Device for removing entrained gases from liquids  
An apparatus and method for removing entrained gases from a liquid by directing a liquid flow adjacent a substantially hydrophobic microporous membrane material and providing a negative pressure to...
6258321 Apparatus and method for cardioplegia delivery  
An apparatus and a method for making a transfer device comprising a tube bundle. The transfer device is suitable for use as a heat exchanger in a blood cardioplegia circuit, for example. The...
6245295 Sample testing apparatus with high oxygen permeable tape providing barrier for closed reaction chamber  
A test sample card has a well formed in the card body for receiving a fluid sample containing a microbiological agent or microorganism and a reagent. The test sample card has a membrane in the form...
6241945 Modular combined pump, filtration, oxygenation and/or debubbler apparatus  
A customized pump, filtration, oxygenation and/or debubbler apparatus includes a first pump module, a filtration module, an oxygenation module, a debubbler module and/or a second pump module. Each...
6117390 Compact blood oxygenator utilizing longitudinally interspersed transversely extending heat exchanger conduits and oxygenator fibers  
A compact blood oxygenator has a minimal priming volume and is particularly advantageous for pediatric cardiac surgery. A generally rectangular housing has longitudinally spaced and interspersed...
6113782 Potting of tubular bundles in housing  
Tubular bundles are potted in a housing, such as in an oxygenator or a pheresis unit. Spacer material is placed into the housing to cover the first ends of the tubular elements. A layer of potting...
6045752 Blood oxygenator with waterless heat exchanger  
Waterless temperature control of blood in a blood oxygenator is achieved by providing a non-disposable heater/cooler with a temperature-controlled surface that can be intimately mated with a...
6010475 Apparatus for the treatment of blood by extracorporeal circulation and process of manufacture  
An apparatus for the treatment of blood or plasma by extracorporeal circulation includes a compartment for the circulation of blood. The compartment is provided with two accesses and has at least...
6001306 Integrated oxygenator and heat exchanger  
A heat exchanger is provided which may be used in an integrated blood oxygenator and heat exchanger. The heat exchanger has a plurality of wave shaped sinusoidal channels on one or both sides. The...
5965433 Portable perfusion/oxygenation module having mechanically linked dual pumps and mechanically actuated flow control for pulsatile cycling of oxygenated perfusate  
A portable perfusion/oxygenation module includes respiratory gas driven dual positive displacement pumps coupled to a stacked membrane oxygenator unit for perfusion fluid oxygenation, a valving...
5964725 Gas exchange apparatus using improved silicone rubber hollow fiber  
A gas exchange apparatus for use as a artificial lung incorporates a hollow fiber module for bundling a plurality of thin-walled hollow silicone fibers. The fibers are wound in the form of a...
5938922 Contactor for degassing liquids  
A contactor for degassing liquids includes a perforated core, a plurality of microporous hollow fibers, and a shell. The fibers surround the core and have two ends. A tube sheet affixes the ends of...
5928179 Method and apparatus for creating pulsatile flow in a cardiopulmonary bypass circuit  
Pulsatile cardiopulmonary flow closely approximating a natural heartbeat is generated in a heart-lung machine by using a proportioning valve to partly convey blood in the machine's cardiopulmonary...
5900142 Mass and thermal transfer means for use in heart lung machines, dialyzers, and other applications  
The process, particularly useful in blood oxygenators, whereby a differential velocity between a fluid and a diffusing surface of hollow tubes by a rotating member such that the boundary layer is...
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