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4622206 |
Membrane oxygenator and method and apparatus for making the same
A membrane oxygenator has a housing and a plurality of microporous hollow fibers disposed within the housing. A gas inlet and a gas outlet are in communication with the microporous hollow fibers. A...
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4620965 |
Hollow fiber-type artificial lung
An artificial lung has an axially extending housing which accommodates a bundle of hollow fibers retained within the housing by a pair of walls provided at the ends of the housing. The housing has...
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4599093 |
Extracorporeal blood processing system
A unitary system incorporates an upper reservoir container having a blood gas separator, a cardiotomy reservoir and a venous reservoir. The upper container is positioned directly above a lower mass...
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4559299 |
Cytotoxicity assays in cell culturing devices
Methods and devices for assaying the sensitivity of of biopsied cells to therapeutic agents are disclosed. Cells are cultured in artificial organs and then contacted with a fluorogenic substrate...
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4556489 |
Membrane oxygenator
A novel device for mass transfer across a membrane is disclosed, which is particularly suitable for use as a blood oxygenator. The novel device is of the type having a pleated, selectively...
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4540492 |
Method and apparatus for treating whole blood
Apparatus for oxygenating blood or for separating whole blood into a plasma fraction and an enriched plasma-depleted blood fraction comprising at least two contiguous membrane units, each unit...
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4486282 |
Precipitation of proteins from salt-containing proteinaceous fluids employing a desalting treatment, and use thereof in selective plasmapheresis
Total or fractional precipitation of proteins from salt-containing proteinaceous solution or suspension mixtures is induced or enhanced by subjecting the proteinaceous mixture to a desalting...
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4469659 |
Sampling device for blood oxygenator
Blood oxygenating apparatus having a sampling access device connected to the blood outlet port and a blood inlet port of the apparatus by a sample supply line and return line and means to cause the...
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4455230 |
Pleated membrane transfer device utilizing potting and thixotropic adhesive
Potting the spaced-apart fold edges of a pleated membrane and spacer stack to the interior of a housing without blocking the fluid passages between the spaced-apart pleats by applying a layer of...
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4451562 |
Blood oxygenator
A membrane type blood oxygenator with a microporous membrane separating blood and air channels, the blood in the blood channels flowing downward to cause any accidentally introduced air bubbles to...
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4444662 |
Microporous laminate
A laminate formed by the solvent casting of a two phase siloxane-polyarylene polyether block copolymer onto a suitable microporous substrate such as a microporous polypropylene film, to produce a...
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4424190 |
Rigid shell expansible blood reservoir, heater and hollow fiber membrane oxygenator assembly
A closed, air-free blood oxygenator assembly having integrated into one self-supporting unit a rigid-shell blood reservoir having an easily visible, concavity which is closed by an attached...
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4414110 |
Sealing for a hollow fiber separatory device
A hollow fiber medical separatory device of the type including a shell containing a plurality of hollow semipermeable fibers extending through a central dialysate chamber and terminating in spaced...
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4411872 |
Water unit for use with a membrane blood oxygenator
Blood units and water units for membrane type blood oxygenator in which blood units are separated from water units by oxygen units; oxygen diffuses through membranes of blood units from oxygen...
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4411786 |
Method and apparatus for separating blood from other fluids during operative procedures
This invention is a method and apparatus for separating blood from other fluids added to the blood in connection with operative procedures. It is particularly exemplified by bypassing a portion of...
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RE31389 |
Non-wicking polyurethane casting systems
A non-wicking polyurethane casting system has been developed which comprises the reaction product obtained by admixing a polyol containing N-N-N'-N'-tetrakis (2-hydroxypropyl) ethylene diamine,...
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4400275 |
Mass transfer apparatus and process
Apparatus for effecting mass transfer between two fluid phases, at least the first of which is a liquid, which apparatus comprises an annular permeable element which is rotatable about its axis of...
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4383921 |
Apparatus for heat or mass transfer
Apparatus for effecting transfer of heat or mass between two fluids through a transfer membrane comprises a conduit for flow of one of the fluids at least partly defined by the membrane. A wall of...
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4376095 |
Hollow fiber-type artificial lung having enclosed heat exchanger
A hollow fiber-type artificial lung having an enclosed heat exchanger comprises a first housing and a second housing connected together coaxially. A gas exchange chamber is defined in the first...
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4374802 |
Oxygenator
A hollow fiber type oxygenator comprising a housing having an inlet port and an outlet port for oxygen and an inlet port and an outlet port for blood, and a plurality of hollow fibers for gas...
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4353799 |
Hydrophobic diffusion membranes for blood having wettable surfaces
Hydrophobic diffusion membranes such as porous polypropylene may be rendered hydrophilic at their surfaces, without losing their valuable characteristics as diffusion membranes, by subjection to a...
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4351797 |
Transfer membrane assembly
A conduit assembly (23) for an artificial lung is formed from two sheets (30) of thermoplastic transfer membrane material which are sealed together along sinuous lines (24) to provide a unitary...
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4346006 |
Diffusion membrane units with adhered semipermeable capillaries
A diffusion membrane unit comprising: in a first embodiment, a planar arrangement of parallel separate capillary membrane tubes and junction lines of adhesive material extending continuously across...
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4342723 |
Gas-exchange sheet members
A sheet member of silicone rubber suitable for use in gas-exchange such as oxygenation and decarbonation of blood in an oxygenator of a mechanical heart and lung is proposed. The sheet member of...
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4328102 |
Membrane apparatus having alternate opposite flow transverse to means flow
A dialyser has a membrane assembly (12) comprising two superposed conduits partially defined, and separated, by a transfer membrane wall. The walls of the conduit are provided with furrowing (38 or...
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4318813 |
Membrane plasmapheresis module
A membrane plasmapheresis module (10) comprises semipermeable membrane means (11) capable of permitting blood plasma to pass therethrough while preventing the passage of blood cells, and sealed...
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4312757 |
Methods and means for circulating a dialysate
The operating efficiency of a mass transfer device such as a blood dialyzer is considerably enhanced by subjecting the blood-carrying semipermeable fibers of the dialyzer to a toroidal dialysate...
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4308230 |
Blood oxygenator
Blood units and water units for membrane type blood oxygenator in which blood units are separated from water units by oxygen units; oxygen diffuses through membranes of blood units from oxygen...
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4306018 |
Method of gas-heat exchange
To supply oxygen to blood and control its carbon dioxide content, the blood is pumped through a silicone rubber tube wound as a helix around an aluminum cylinder. In a typical use, water at 37° C....
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4284506 |
Biomedical devices
The present invention is directed to improved separatory devices employing polyurethane forming compositions, such as hollow fiber separatory devices intended to be used in biomedical applications....
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4272373 |
Apparatus for the transfer of substances between two fluids with simultaneous tempering of at least one of the fluids
Apparatus for the transfer of substances between two fluids with the simultaneous tempering of at least one of the fluids. The apparatus includes at least one heat permeable membrane having first...
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4268279 |
Gas transfer process with hollow fiber membrane
A process which comprises allowing a liquid to contact with the inside of a microporous hollow fiber and a fluid to contact with the outside, thereby allowing the gaseous components contained in...
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4256692 |
Membrane oxygenator
A membrane device having particular utility as a blood oxygenator is disclosed. The device comprises a housing having an oxygen inlet and outlet, a blood inlet and outlet, and a water inlet and...
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4244824 |
Molded body with inclusions
A molded polymer body with very fine, discrete, solid particles composed of a metal, metal compound or a mixture of the same incorporated within the molded body in a uniform pattern of...
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4239729 |
Oxygenator
An oxygenator comprises a cylindrical housing provided with inlet and outlet ports for oxygen, and a bundle of hollow fibers disposed within the housing. The porous hollow fibers are made of...
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4239728 |
Apparatus and method for the diffusion of substances between two fluids separated by a semipermeable membrane
An apparatus and method for the diffusion of substances between two fluids. The apparatus comprises at least one semipermeable membrane having first and second opposing surfaces, first conducting...
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4231878 |
Capillary mass transfer device
This disclosure relates to a capillary mass transfer device suitable for use as an artificial kidney or an artificial lung and including a plurality of capillary tubes through which blood may flow....
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4219422 |
Apparatus for mass transfer between fluids, provided with an interposed selectively permeable diaphragm unit
Apparatus for mass transfer between fluids, comprises two permeable membranes with a porous membrane support sandwiched therebetween, all pleated together with an accordian pleat to form a pleat...
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4213858 |
Supporting net
A supporting net is disclosed including an outer layer of first strands, said first strands being spaced apart and substantially parallel to each other; an intermediate supporting layer of second...
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4214020 |
Processes for coating bundles of hollow fiber membranes
Processes are disclosed for coating the exteriors of a plurality of hollow fibers which are suitable for fluid separations and which are assembled in the form of a bundle. The processes involve...
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4212741 |
Blood processing apparatus
The disclosure sets forth blood processing apparatus of the general type which employs a cylindrical rotor with a semi-permeable membrane at its outer surface, rotatable within a surrounding...
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4210529 |
Blood compatible polymers and applications thereof
Fluoroacylation of ethyl cellulose has been found to result in good gas permeability and blood compatibility for polymeric layers made from the resulting fluorinated esters. The fluoroacylated...
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4204963 |
Sealing members for a membrane diffusion device
Improvements are provided in the sealing arrangment and in an inflatable shim for a membrane diffusion device which comprises a stack of membrane sections and means for defining interleaving flow...
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4199458 |
Membrane diffusion device with external compression
A membrane diffusion device, such as a membrane oxygenator, is disclosed which comprises a stack of flat membrane wall pairs and flat membrane supports in alternating, interleaving relation. The...
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4196075 |
Membrane fluid transfer method and apparatus
A method and apparatus for fluid transfer across a membrane wherein transfer fluid is passed through the interior of a wrapped, permeable, flattened, tubular membrane and fluid to be processed is...
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4182653 |
Mass transfer between fluids and apparatus therefor
The oxygenation and removal of carbon dioxide from blood by simultaneous mass transfer through a microporous membrane is improved by pulsing the flow of oxygenating gas over the membrane. This...
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4179364 |
Diffusion device for blood
In a convoluted-membrane type diffusion device for blood, such as a blood oxygenator, in which the membrane is supported by a stiff, folded, integral backing having port means for fluid flow...
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4176070 |
Semi-permeable membranes of regenerated cuprammonium cellulose and method for heat sterilization thereof in physiological saline
Semi-permeable membranes of regenerated cellulose are subjected to wet-heat sterilization at a temperature of 105° to 140° C. During the treatment, the membranes are maintained in contact with an...
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4176069 |
Device for exchanging substances and method of manufacturing the device
A device for exchanging substances, in particular, an oxygenator or dialyzer, comprises a stack of semipermeable membranes each having a plurality of longitudinally oriented capillaries embedded...
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4170559 |
Hollow fiber separatory device
A hollow fiber separatory device is provided wherein a polyurethane prepolymer is cross-linked or cured with an ester of a polyhydric alcohol which contains two or three hydroxyl groups, e.g.,...
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