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7626704 |
Methods and systems for simultaneous real-time monitoring of optical signals from multiple sources
Methods and systems for real-time monitoring of optical signals from arrays of signal sources, and particularly optical signal sources that have spectrally different signal components. Systems...
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7626703 |
Optical microscopy with phototransformable optical labels
Spatially-structured activation radiation having relatively high- and low-intensity regions is provided to a sample that includes phototransformable optical labels (“PTOLs”). A subset of the...
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7623242 |
Device and method for monitoring multiple chemical samples with a fluorescent tube
A monitoring device is described for multiple chemical reactions in multiple test containers. Each container contains chemical reagents and at least one fluorescence dye indicator capable of...
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7623233 |
Optical analysis systems and methods for dynamic, high-speed detection and real-time multivariate optical computing
Multivariate optical analysis systems employ multivariate optical elements and utilize multivariate optical computing methods to determine information about a product carried by light reflected...
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7615376 |
Masking background fluorescence and luminescence in the optical analysis of biomedical assays
In a process for the quantitative optical analysis of fluorescently labelled biological cells 5 , a cell layer on a transparent support at the bottom 2 of a reaction vessel 1 is in contact...
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7612883 |
Dynamic plasmonics-enabled signal enhancement, a device comprising the same, and a method using the same
Disclosed herein is a plasmonics platform comprising a substrate; a plurality of periodically spaced nanoholes and/or nanoparticles disposed upon the substrate; wherein the average first order of...
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7605920 |
Detector system for unidentified substances
Disclosed herein is a method of identifying a unidentified substance, comprising directing light from a light emitting source directly upon a stationary unidentified substance; collecting...
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7602494 |
Method of imaging fluorescence and fluorescence imaging apparatus
A method of imaging fluorescence, in which an inverted fluorescence imaging apparatus provided with an immersion objective is used to image an observation phosphor for a constant term, includes an...
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7602479 |
Light emission measuring apparatus and light emission measuring method
A light fluctuation measuring apparatus, comprising a parameter setting unit 2 which sets parameters of a microscopic image obtaining unit and/or parameters of a light emission measuring unit...
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7592588 |
Calibration source infrared assembly for an infrared detector
Provided is a calibration source IR assembly for an IR detector including an IR focal plane. The calibration assembly includes a rotatable spectral filter wheel optically coupled to an IR focal...
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7589839 |
Examination apparatus, fluoroscopy apparatus, examination method, and experimental method
A microscope examination apparatus is provided that includes a light source for emitting excitation light or illumination light to a specimen placed on a stage; an objective lens opposing the stage...
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7586600 |
Normalization of data
Methods for normalizing output from an instrument employing a reference standard or non-fluorescing substance disposed within at least one of a plurality of reaction chambers. The method comprises...
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7583381 |
Miniaturized fluorescence analysis system
According to embodiments of the present invention, a fluorescence analysis system includes a light emitting diode to excite a fluorophor sample for analysis. The system includes an LED driver that...
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7577064 |
Microplate reader with intelligent filter slide
Microplate reader ( 21 ) with a computer for controlling the components of said microplate reader ( 21 ), comprising a light source ( 15 ) for emitting light for irradiating samples ( 22 ) or...
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7576862 |
Measuring time dependent fluorescence
Methods and apparatus, including computer program products, implementing and using techniques for collecting optical data pertaining to one or more characteristics of a sample. A light beam of a...
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7576844 |
Systems and methods for use in detecting harmful aerosol particles
The invention provides systems and methods for detecting aerosols. The systems and methods can be used to detect harmful aerosols, such as, bio-aerosols.
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7570359 |
Illuminating and panoramically viewing a macroscopically-sized specimen along a single viewing axis at a single time
Simultaneous illumination along each of multiple axis for panoramic viewing of a macroscopically-sized specimen along a single viewing axis is realized by dichroic mirrors. Selective control of...
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7567347 |
Fluorometers
In apparatus for the production and detection of fluorescence at a sample surface, the height of the apparatus above the sample surface is reduced, and loss of the emitted fluorescence due to...
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7564541 |
System for obtaining images in bright field and crossed polarization modes and chemical images in raman, luminescence and absorption modes
An integrated system including one or more light sources, at least one processor, an optical lens, a two-dimensional tunable filter, one or more two-dimensional array of detection elements and...
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7554664 |
Laser scanning microscope
Laser Scanning Microscope with an illumination beam path for illumination of a sample and a detection beam path for wavelength-dependent recording of the light from the sample, whereby filters for...
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7554663 |
Systems and methods for use in detecting harmful aerosol particles
The invention provides systems and methods for detecting aerosols. The systems and methods can be used to detect harmful aerosols, such as, bio-aerosols.
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7545498 |
System and method for removing auto-fluorescence through the use of multiple detection channels
A system and method permits for the separation of auto-fluorescence from a signal by applying a single probe to a sample, exciting the sample with a single wavelength light source, thereby emitting...
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7535568 |
Biochip, biochip reader and biochip reading method
A biochip for implementing analysis on the basis of the distribution of a quantity of light of fluorescent light generated at sites disposed thereon, the biochip having, markers formed thereon and...
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7525660 |
Systems and methods for use in detecting harmful aerosol particles
The invention provides systems and methods for detecting aerosols. The systems and methods can be used to detect harmful aerosols, such as, bio-aerosols.
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7525653 |
Spectroscopic chemical analysis methods and apparatus
Spectroscopic chemical analysis methods and apparatus are disclosed which employ deep ultraviolet (e.g. in the 200 nm to 300 nm spectral range) electron beam pumped wide bandgap semiconductor...
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7524458 |
Screen plate of an imaging measuring instrument
Screen plate ( 10 ) of an imaging measuring instrument, intended for use in absorption measurement of samples relating to the fields of biochemistry and medicine. The screen plate comprises a plate...
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7518727 |
Multicapillary multilaser detection system
A system for detecting electromagnetic radiation from samples comprising: a plurality of sample volumes, each of said sample volumes confined within a portion of a capillary column; a plurality of...
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7518710 |
Optical devices for biological and chemical detection
A biological and chemical detection system is provided that detects and identifies biological and/or chemical particulates of interest. The biological and chemical detection system comprises a...
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7515268 |
Fluorescence-activated cell detector
An apparatus, and method of use of such apparatus, for detecting particles of interest that are dispersed in a fluid mix, which typically includes other particles. The apparatus includes an...
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7508516 |
Biochip reading apparatus and biochip reading method
A site position can be detected using transmitted light or reflected light which does not include an excitation wavelength according to a configuration of a biochip 60 . When reflected light is...
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7508504 |
Automatic wafer edge inspection and review system
A substrate illumination and inspection system provides for illuminating and inspecting a substrate particularly the substrate edge. The system uses a light diffuser with a plurality of lights...
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7502113 |
Automated seed sampler and methods of sampling, testing and bulking seeds
An automated seed sampler includes a sampling station; a sampler for removing material from a seed in the sampling station; a seed conveyer for conveying the seed from the sampling station to a...
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7499167 |
Aerosol trigger device and methods of detecting particulates of interest using an aerosol trigger device
A trigger device for detecting particles of interest comprises a sample substrate, a collector, a read head and a processor. The collector is positioned proximate to at least a portion of a first...
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7499166 |
Wide field imager for quantitative analysis of microarrays
This invention provides an imaging system for high-accuracy quantitative analysis of a microarray. In certain embodiments, the system comprises a broad band excitation light source that provides...
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7499153 |
Use of high wavenumber Raman spectroscopy for measuring tissue
The invention is related to the instrument for measuring a Raman signal of tissue, the instrument comprising a laser, a signal detection unit for measuring the Raman signal, and a fiber optic...
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7491924 |
Combination reader
An apparatus for imaging an array of a plurality of features associated with a sample tile. The apparatus includes a stage that supports the sample tile in an illumination region, and an...
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7489402 |
Optical collection geometries for phase fluorimetry
An apparatus and method for the stimulation and collection of fluorescent signals from a target analyte. The apparatus comprises:
i) a frequency modulated optical source which emits...
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7489401 |
Device for detecting emission light of micro-object
In the detection of fluorescence Lf emitted by a micro-object irradiated with an excitation light Le by a semiconductor light-detecting element 20, a converging microlens 62 for converging the...
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7480046 |
Scanning microscope with evanescent wave illumination
A scanning microscope includes a light source for evanescently illuminating a sample disposed on a slide. A point detector receives detection light emanating from a scanning point of the sample. A...
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7480045 |
Controlling pulses in optical microscopy
A method for imaging a sample is described. The sample is characterized by a limit on incident optical energy absorbed over a given time period. The method includes providing at least one input...
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7474398 |
Illumination system for an imaging apparatus with low profile output device
A fluorescence illumination system is provided for use with an imaging apparatus that defines a light-tight imaging compartment. The fluorescence illumination system includes a trans-illumination...
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7466419 |
Spectral instrument
In this spectral instrument, a plurality of interference filters 31, 32 . . . with transmitting wavebands different from each other are arranged in order so that light reflected by a specific...
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7466418 |
Fluorescence illumination assembly for an imaging apparatus and method
A macroscopic fluorescence illumination assembly is provided for use with an imaging apparatus with a light-tight imaging compartment. The imaging apparatus includes an interior wall defining a...
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7466408 |
Measurement system
A measurement system that optically measures in turn a plurality of samples arranged in an array via an objective lens and an imaging lens is disclosed, which is characterized by comprising an...
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7463357 |
Wide dynamic range chemical array reader
A system for detecting a predetermined wavelength of light emitted from an area on the surface of a chemical array is provided. Aspects of the system include: a beam splitter for splitting emitted...
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7456954 |
Modulated excitation fluorescence analysis
Fluorescence, spectroscopy is used to analyze small numbers of molecules that are present in a relatively small detection volume or zone. Information regarding physical and chemical properties of...
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7456953 |
Method and apparatus for improved light distribution in an anti-resonant waveguide sensor
An improved method of analyzing target analytes in a sample is described. The method is based on creating an approximately homogeneous distribution of light in an anti-resonant guided optical...
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7446867 |
Method and apparatus for detection and analysis of biological materials through laser induced fluorescence
The present invention provides a method and an apparatus to analyze fast and accurately biological samples. The method includes prior mapping of the DNA chip with a CCD camera, addressed excitation...
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7436501 |
Microscope
In one or more embodiments, a microscope has a first pulsed laser and a second pulsed laser arranged to irradiate a specimen. Coherent Raman scattering light emanated from the irradiated specimen...
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7426027 |
Small object identifying device and its identifying method
A small object identifying device and its identifying method according to which a large number of small objects can be identified. In one embodiment, the device includes a dispersion region section...
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