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7414725 Method and apparatus for a microscope image selector  
The disclosure generally relates to a multimode imaging apparatus for simultaneously obtaining multiple wavelength-discriminative spectral images of a sample. In one embodiment, the apparatus...
7411679 Optical filter and fluorescence spectroscopy system incorporating the same  
An optical filter including at least one substrate and first and second thin-film interference filters disposed directly on the substrate. The interference filters include a plurality of hard...
7411672 Method and apparatus for chemical imaging in a microfluidic circuit  
The disclosure generally relates to a system for detecting a change in an attribute of a substance. The system may include a photon source for producing a first of a plurality of photons which...
7408636 Method and apparatus for dark field chemical imaging  
The disclosure is generally directed to a method and apparatus for providing an image of a sample. The apparatus includes an illuminating source for transmitting photons to a sample. The...
7405823 Signal noise reduction for imaging in biological analysis  
A system and method for characterizing contributions to signal noise associated with charge-coupled devices adapted for use in biological analysis. Dark current contribution, readout offset...
7400405 Pesticide detector and method  
Highly portable, handheld instrument which can be pointed at the produce to be checked. Light from a source within the instrument is directed onto the produce to induce fluorescent emission from...
7394542 Method and apparatus for chemical imaging in a microfluidic circuit  
The disclosure generally relates to a system for detecting a change in an attribute of a substance. The system may include a photon source for producing a first of a plurality of photons which...
7391512 Integrated optoelectronic system for measuring fluorescence or luminescence emission decay  
An optoelectronic system for measuring fluorescence or luminescence emission decay, including (a) a light source being a light emitting diode, a semiconductor laser or a flash tube; (b) a first...
7388664 Methods for improving the performance of a detector  
A system and method for allowing adjustments of various parameters associated with the operation of charge-coupled devices adapted for use in biological analysis devices. Gate voltage signal...
7375811 Fatigue-degree evaluation device  
A fatigue-degree evaluation device is provided for easily evaluating a degree of fatigue of a living body. Embodiments include a device wherein fluorescent light generated via a liquid excreted...
7372570 Incident light redistribution to compensate for radial gradient in detector  
Nonuniformities in the efficiency of detection of individual fluorescing reaction mixtures in a well plate with a two-dimensional array well array are corrected. The nonuniformities arise both from...
7362432 Method and systems for dynamic range expansion  
Methods and systems for expanding the dynamic range of a system are provided. One method includes splitting fluorescent light emitted by a particle into multiple light paths having different...
7355710 Optical system and method for exciting and measuring fluorescence on or in samples treated with fluorescent pigments  
An optical system for exciting and measuring fluorescence of samples has a first laser; a deflection element; a mirror; and an optic fixed in relation to one another. A unit is linearly movable...
7349093 Fluorescence measurement apparatus  
On a substrate 41 holding a sample to be detected, a dielectric multilayer 42 is disposed which reflects excitation light e 1 supplied from above the substrate 41 and transmits fluorescence...
7342223 Mass spectrometer for biological samples  
The mass spectrometer according to the present invention includes a light source for emitting pulse light including a plurality of wavelengths; an ionizer for ionizing molecules of a sample by...
7339667 Dark box apparatus for fluoroscopy, fluoroscopy system, and fluoroscopy method  
Noise in a fluorescence image acquired during fluoroscopy is eliminated to present a clear fluorescence image, and the relative positional relationship between the fluoroscopy unit and the specimen...
7339657 Low-cost on-line and in-line spectral sensors based on solid-state source and detectors combinations for monitoring lubricants and functional fluids  
A series of optical spectral sensors is based on a combination of solid-state sources (illumination) and detectors housed within an integrated package that includes the interfacing optics and...
7336355 Fluorescence spectroscopic apparatus  
There is provided a fluorescence spectroscopic apparatus includes an exciting optical unit configured to irradiate the same sample area with a plurality of excitation lights of different wavelength...
7333204 Method and device for analysing a gas likely to contain particles or suspended aerosols  
The present method uses a spectrophotometric and/or ionisation detection device in which the gas to be analyzed and illuminated by a light source emitting in a range of wavelengths distinct from...
7330252 Porous silicon on-chip spectroscopy system  
Embodiments of the present invention provide a miniaturized spectroscopy system comprising a light source fabricated from porous silicon. Porous silicon light emitting devices can provide tunable,...
7330243 Method for monitoring the production of biomolecule crystals  
The invention relates to a method for monitoring the production of macromolecule crystals containing at least one fluorescence emitter, comprising the following steps: a) a solution volume with...
7327459 Fluorescence detector for detecting microfluid  
An ultra small fluorescence detector capable of detecting in real time reaction undergoing in a micro chamber having a predetermined volume and disposed on a microfluid chip is provided. The...
7324200 Fluorescence photometric apparatus  
A fluorescence photometric apparatus which includes a light source, a light irradiating unit configured to condense light from the light source on a sample by means of an objective lens and...
7317515 Method of localizing fluorescent markers  
The invention describes a method of determining the position of fluorescent markers in a sample ( 4 ), with a high spatial resolution. To this end, the sample ( 4 ) is illuminated with an exciting...
RE39977 Near infrared chemical imaging microscope  
A chemical imaging system is provided which uses a near infrared radiation microscope. The system includes an illumination source which illuminates an area of a sample using light in the near...
7315376 Fluorescence detection system  
Apparatus and methods for exciting and detecting fluorescence in samples are disclosed. In one embodiment, a sample holder for holding a plurality of samples is provided together with an optical...
7310147 Robotic apparatus for picking of cells and other applications with integrated spectroscopic capability  
A robotic apparatus of the kind having a sample manipulation head with associated positioning system mounted above the main bed of the apparatus, as used for picking of cells, in particular animal...
7304741 Pesticide detector and method  
Highly portable, handheld instrument which can be pointed at the produce to be checked. Light from a source within the instrument is directed onto the produce to induce fluorescent emission from...
7304733 Method and device for conducting the spectral differentiating, imaging measurement of fluorescent light  
A method and a device for image producing measurement of fluorescent light, according to which a sample containing fluorophores of different species is irradiated with excitation light of at least...
7301637 Dark field imaging device for the spatially-resolved dark field imaging of a sample and examination method  
Described is a dark-field imaging device for the spatially resolved dark-field imaging of a sample ( 60 ), especially a fluorescent sample, comprising, for the illumination of the sample with...
7298476 Method and system for far-field microscopy to exceeding diffraction-limit resolution  
The bio-sample (e.g., a live cell) is labeled with a proper number of nanoparticles. Each nanoparticle is pre-co-doped with a controlled ratio of fluorophore donors and acceptors. Two laser pulses...
7297961 Fluorescence microscope and observation method using the same  
The present invention relates, in general, to a fluorescence microscope and method of observing samples using the microscope and, more particularly, to a fluorescence microscope and method of...
7295316 Fluorescent detector with automatic changing filters  
A fluorometry device and method adapted to determine concentration of spectrally distinguishable species in a biological sample with a plurality of movable optical devices.
7289217 Fluorescent detector with automatic changing filters  
A fluorometry device and method adapted to determine concentration of spectrally distinguishable species in a biological sample with a plurality of movable optical devices.
7289205 Fluorescence polarization imaging devices and methods  
The present invention is directed to a novel multi-spectral exogenous fluorescence polarization imaging technique that enables rapid imaging of large tissue fields. The imaging device includes a...
7286232 Fluorescence filtering system and method for molecular imaging  
An optical system is disclosed that can be used for fluorescence filtering for molecular imaging. In one preferred embodiment, a source subsystem is disclosed comprising a light source and a first...
7286224 Time-multiplexed scanning light source for multi-probe, multi-laser fluorescence detection systems  
An apparatus images a surface. An imager stage linearly translates the surface in a first direction. A light path has a first end defining an input aperture perpendicular to the first direction and...
7283241 Method and apparatus for a microscope image selector  
The disclosure generally relates to a multimode imaging apparatus for simultaneously obtaining multiple wavelength-discriminative spectral images of a sample. In one embodiment, the apparatus...
7283229 Small object identifying device and its identifying method  
A small object identifying device and its identifying method according to which a large number of small objects can be identified. In one embodiment, the device includes a dispersion region section...
7280213 Light detection device  
A microplate reader includes a light emitting portion for irradiating each of a plurality of test samples with excitation light, a light receiving portion for receiving return light from each of...
7280202 Ingredient analysis method and ingredient analysis apparatus  
In an ingredient analysis method and an ingredient analysis apparatus in accordance with the present invention, high-frequency power is supplied from a power source 4 while helium gas is supplied...
7274455 Optical detection apparatus for multi-channel multi-color measurement and multi-channel sample analyzer employing the same  
Provided are an optical detection apparatus which can measure multi-channel samples at high speed and various wavelengths using an optical detector and a multi-channel sample analyzer employing the...
7268878 Fluorescence correlation spectroscopy instrument and method of using the same  
Disclosed is a portable fluorescence correlation spectroscopy instrument that includes an excitation source, at least one of a light focusing element positioned to receive light emitted by the...
7262839 Method and apparatus for compact birefringent interference imaging spectrometer  
The disclosure relates to a method and apparatus for a compact birefringent interference imaging spectrometer. More specifically, the disclosure relates to a portable system for obtaining a...
7256892 Measuring instrument and fluorometric method  
A measuring instrument that comprises a light source unit 1 capable of emitting light having different wavelengths, a light receiving unit 2 that outputs an electrical signal corresponding to...
7248363 Particle size analyzer  
A laser diffraction particle size analyzer irradiates a laser beam on particles in a scattered state, and measures a spatial intensity distribution of diffracted and scattered light from the...
7247443 Sensor constructs and detection methods  
Sensor constructs for detecting the presence of an analyte in a sample comprise a molecular scaffold, a pair of labels which interact via Förster resonance energy transfer, and at least one...
7245369 Spectroscopic apparatus using spectrum narrowed and stabilized laser with Bragg grating  
An apparatus for measuring properties of physical matters by means of Raman spectroscopy including a laser element, a wavelength dispersion element, an array or single element detector, and a...
7242472 Biochip detection system  
The present invention discloses a biochip detection system for detecting a biochip labeled with multiple fluorophores. The biochip detection system comprises a broadband light source for generating...
7233393 Signal noise reduction for imaging in biological analysis  
A system and method for characterizing contributions to signal noise associated with charge-coupled devices adapted for use in biological analysis. Dark current contribution, readout offset...
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