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5628963 |
Apparatus for quanitative evaluation of agglutination reactions
In the method for quantitative evaluation of agglutination reactions between a reagent and a biological fluid to be examined, the reagent and the biological fluid are intimately mixed by a...
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5615673 |
Apparatus and methods of raman spectroscopy for analysis of blood gases and analytes
The present invention relates to systems of methods of measuring selected analytes in blood and tissue using Raman spectroscopy to aid in diagnosis. More particularly, Raman spectra are collected...
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5616501 |
Reticulocyte analyzing method and apparatus utilizing light scatter techniques
A reticulocyte analyzing method and apparatus in which a biological sample stream of ghosted red cells is passed into and through a point focused beam of light, such as laser light. A light...
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5611337 |
Pulsoximetry ear sensor
A one-piece injection molded elastic plastic peg-like or clip-like support for sensor elements of a pulsoximetry ear sensor has legs interconnected by an elastically deformable rib. The rib runs in...
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5605152 |
Optical glucose sensor
An improved glucose sensor adapted for in vivo implantation includes one or more optical fiber optrodes mounted within a semipermeable probe housing designed for differential diffusion of glucose...
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5605805 |
Automatic lineage assignment of acute leukemias by flow cytometry
A method for automatic lineage assignment of acute leukemias. Eight four-parameter list mode data files are acquired with a flow cytometer in the following sequence: 1. unstained; 2. isotype...
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5601080 |
Spectrophotometric blood analysis
A spectrophotometric method and device are described which are particularly useful for on-line monitoring and control of blood parameters. Determination of a blood parameter without measuring or...
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5601079 |
Non-invasive quantification of glucose control, aging, and advanced maillard products by stimulated fluorescence
An apparatus for measuring the concentration of selected solute in a solution. This apparatus is particulary suitable for measuring the concentration of blood components, such as blood late...
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5598842 |
Non-invasive blood analyzer and method using the same
A non-invasive blood analyzer includes a light application device for applying light to a detection region of vessels contained in part of the living body, an imaging device for imaging the...
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5589932 |
Spectrophotometric method and apparatus for the characterization of blood and blood types
A method and apparatus for determining the type of a blood sample are provided wherein a turbidity spectrum of the blood sample is collected over a predetermined wavelength range, from which is...
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5590052 |
Error checking in blood analyzer
The present invention provides various methods for detecting errors in a blood analysis system. The system includes a blood analyzer and a molded plastic rotor with a series of chambers and...
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5582170 |
Fiber optic sensor for in vivo measurement of nitric oxide
A fiber optic sensor for measurement of in vivo nitric oxide concentrations in a subject. The sensor contains a nitric oxide-sensing compound in a polymer matrix attached to an optical fiber. The...
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5575977 |
Apparatus for sedimentation based blood analysis
An apparatus and process for accurately determining settling data for the settling of erythrocyte cells from a plasma fluid in a test specimen of blood. The apparatus includes a settling tube, a...
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5567869 |
Method and apparatus for quantitation of relevant blood parameters
A method for quantitation of blood parameters comprises the steps: provision of a sample of plasma, serum or blood, entering the sample into a cuvette with an internal dimension less than 1 mm,...
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5564417 |
Pathlength corrected oximeter and the like
A pathlength corrected spectrophotometer for tissue examination includes an oscillator for generating a carrier waveform of a selected frequency, an LED light source for generating light of a...
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5565976 |
Method and apparatus for detecting and compensating for a kink in an optic fiber
A method and apparatus are provided for detecting and compensating for a kink in an optical fiber. A distal sensor (11) monitors a level of a parameter in an environment in which the distal sensor...
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5565977 |
Systems and methods for identifying and controlling interfaces between blood components
Systems and methods locate at least three spaced apart sensing units in association with volume of blood comprising a first blood component region, a second blood component region, and an interface...
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5560889 |
Sample treatment apparatus
A sample treatment apparatus includes a sample sucking section, a sample concentration detecting section, and a sample condensing section. The sample concentration detecting section detects a...
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5561517 |
Method and apparatus for flow type particle image analysis using a pulse light emitted at any of an odd and even image field reading-out period
A method and an apparatus for flow type particle image analysis generate a pulse light emission in any one of the odd and the even field image reading-out periods, and multiple exposure is...
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5557098 |
System to identify bags disinfected by irradiation which punches holes in a polarized portion of the bag to indicate processing thereof
A system and a method are provided for detecting a bag that has been subjected to a process, such as illumination, wherein the contents of the bag require processing before subsequent use. The...
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5551422 |
Method and apparatus for analytical determination of glucose in a biological matrix
A method for determining glucose concentration in a biological matrix includes the steps of performing at least two detection measurements. In each detection measurement light is irradiated at a...
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5541064 |
Methods and apparatus for immunoploidy analysis
A method and apparatus are provided for selecting and analyzing a subpopulation of cells or cell objects for a certain parameter such as DNA using image analysis means. The cells are first stained...
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5526111 |
Method and apparatus for calculating a coagulation characteristic of a sample of blood a blood fraction or a control
A method for calculating a coagulation characteristic of a sample of blood, a blood fraction, or a control comprises generating an output signal indicative of coagulation of the sample, sampling...
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5526258 |
Method and apparatus for automated analysis of biological specimens
An apparatus and method for analyzing the cell objects of a cell sample for the diagnosis and treatment of actual or suspected cancer is disclosed. An image of the cell sample is first digitized...
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5525518 |
Method of photometric in vitro determination of a blood gas parameter in a blood sample
A method of photometric in vitro determination of at least one blood gas parameter in a sample of whole blood. The whole blood sample is obtained by connecting an at least partially transparent...
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5522388 |
Pulse spectrometer
A pulse spectrometer for noninvasively determining the concentration of blood constituents in in vivo tissue comprises a pressure application device for applying pressure to a measurement region of...
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5521699 |
Imaging flow cytometer and imaging method having plural optical paths of different magnification power
An imaging flow cytometer includes a flow path such as a transparent tube for allowing subject particles to move in a separate fluidity, the subject particles being present in a sample liquid, a...
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5518923 |
Compact blood culture apparatus
The present invention describes an apparatus for detecting biological activities in a large number of blood culture containers. The containers are placed in a plurality of wells arranged in...
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5513642 |
Reflectance sensor system
A method for determining the content of chemical constituents in a biological tissue medium includes providing a probe comprising a light source and a plurality of photodetector strips...
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RE35227 |
Process and apparatus for analyzing cells
A cell analyzing system flows a liquid to be tested and a sheath liquid through a flattened flow passage. An image of the flattened flow passage is formed at two different magnifications. The...
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5510267 |
Flow cytometry lytic agent and method enabling 5-part leukocyte differential count
A lytic agent is described which when mixed with whole blood, lyses the red cells instantly, but does not affect the optical, light scattering properties of the white blood cells for at least 30...
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5506148 |
Method for activation of polyanionic fluorescent dyes in low dielectric media with quaternary onium compounds
The invention pertains to a method for generating the fluorescence of polyanionic fluorophores in low dielectric media with fluorescence activation produced by specific quaternary onium compounds....
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5502651 |
Potentiophotometric fibrinogen determination
An apparatus and a method are disclosed for measuring the concentration of fibrinogen that contributes to the clotting of blood. The apparatus utilizes a potentiophotometer that provides an output...
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5495105 |
Method and apparatus for particle manipulation, and measuring apparatus utilizing the same
A flow of liquid containing floating fine particles is formed in a flow path, thereby causing successive movement of the particles. A light beam having intensity distribution from a laser is...
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5488469 |
Cell analyzing apparatus
A cell analyzing apparatus which employs flow cytometry to obtain the concentration (the cell count per unit volume) of a specimen under examination is adapted to measure either the cell count of a...
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5487112 |
Method and apparatus for time-resolved measurements of lymphocyte function and aggregate structure using computer-automated microscopy
A method and apparatus for the analysis of magnified video image data to develop quantitative functional and morphological indices for cell-to-cell adhesion. Such induces permit distinction between...
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5473706 |
Method and apparatus for automated assay of biological specimens
An apparatus and method for automated assay of biological specimens positioned on microscope slides. The apparatus comprises an interactive optical subsystem for viewing the biological specimen on...
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5471981 |
Method and apparatus for converting a modulated optical signal to an electrical signal with correction for modulation jitter
A method for accurately converting to an electrical signal a modulated optical signal, the modulation frequency of which randomly varies in a narrow range about a predefined optimum modulation...
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5471294 |
Flow imaging cytometer
Disclosed is a flow imaging cytometer having a flow cell one side of which is irradiated with excitation light, in which wavelength selecting means for reflecting excitation light and transmitting...
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5469251 |
Apparatus for detecting fluorescence of particles in a fluid and analyzing the particles
An apparatus for analyzing particles at high precision capable of obtaining informations in real time such as morphological informations and fluorescence image of cells (particles) contained in a...
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5460177 |
Method for non-invasive measurement of concentration of analytes in blood using continuous spectrum radiation
Method for non-invasive detection of the concentration of a constituent in blood of a living animal includes the steps of irradiating a body part of the animal with intensity-modulated radiation...
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5458128 |
Method and apparatus for noninvasively measuring concentration of a dye in arterial blood
The method of noninvasively measuring concentration of a dye in a circulatory system includes measuring an optical density of an arterial blood-dye mixture in an artery as a function of time at a...
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5457526 |
Apparatus for analyzing particles in fluid samples
An apparatus for analyzing particles capable of obtaining the morphological information or absorption information of particles such as cells in a liquid sample or particles moving in a fluid in...
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5452716 |
Method and device for in vivo measuring the concentration of a substance in the blood
In vivo measurement of the concentration of a substance in the blood, e.g. glucose, despite varying concentrations of interfering components, e.g. protein and fat, by measuring the absorption of...
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5448992 |
Method and apparatus for non-invasive phase sensitive measurement of blood glucose concentration
A method and apparatus for non-invasive measurement of blood glucose concentration based on producing a polarized-modulated laser beam via a polarizing frequency shifter (24), measuring a phase...
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5449622 |
Method and apparatus for analyzing stained particles
In a stained particle analyzing method and apparatus for staining a test sample containing suspended particles, shooting an image of the stained sample, and classifying the particles and computing...
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5448349 |
Particle analyzing apparatus and method wherein an optical deflector optically tracks a particle
A particle image analyzing apparatus including, a flow cell for enclosing a solution containing a particle to be analyzed in a sheathed flow to form the solution into a sample solution flow, an...
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5441054 |
Apparatus for measuring absorption information in scattering medium and method therefor
Modulated light from a light source is incident on the surface of a scattering medium, and light passing through this scattering medium is externally detected. A signal of a predetermined frequency...
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5436978 |
Method and an apparatus for differentiating a sample of biological cells
A method for quickly and easily identifying the five basic components of leukocyte cells: basophils, eosinophils, neutrophils, monocytes and lymphocytes is disclosed. The method measures the size...
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5432061 |
Method and apparatus for detecting microorganisms
The present invention describes a method and apparatus for detecting microorganisms in a large number of blood culture vials using more than one microorganism detection principle for each vial. Two...
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