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5883378 |
Apparatus and methods for transmitting electrical signals indicative of optical interactions between a light beam and a flowing suspension of particles
A system and methods for transmitting analog signals, particularly analog signals derived from an optical signal intensity, in a noisy environment over a length of cable. The optical signal is...
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5882940 |
Method for assaying photosensitizing drug in plasma
A concentration of a photosensitizing drug in a patient, for PhotoDynamic Therapy treatment of the patient by a treatment light at a treatment light wavelength, is determined by the steps of...
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5880835 |
Apparatus for investigating particles in a fluid, and a method of operation thereof
In order to investigate particles in a fluid, a flow cell causes the fluid to flow past a sensor which receives light from a continuous light emission system. When the sensor detects a change in...
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5879900 |
Method for simultaneous analysis of cell viability, nucleated red blood cells and white blood cell differentials
A method for the simultaneous and quantitative, flow cytometric analysis of nucleated red blood cells (NRBC), white blood cells (WBC), damaged white blood cells and a white blood cell subclass...
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5875258 |
Biological specimen analysis system processing integrity checking apparatus
A suite of tests and parameter monitoring methods for at least five major subsystems that are found in most automated image processing systems, as well as calibration routines for three major...
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5851835 |
Multiparameter hematology apparatus and method
A multi-parameter hematology analyzer and method are provided for in vitro determination of blood parameters. The analyzer apparatus includes a laser for transmitting light through a specimen...
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5846702 |
Reagent including an osmium-containing redox mediator
A new group of Os(II) and Os(III) compounds useful as redox mediators in electrochemical biosensors. These compounds have 1) low oxidation potential, 2) fast reaction kinetics between the...
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5846834 |
Method for assaying photosensitizing drug in whole blood
A concentration of a photosensitizing drug in a patient, for PhotoDynamic Therapy treatment of the patient by a treatment light at a treatment light wavelength, is determined by the steps of...
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5841523 |
Method for performing spectroscopic analysis of inhomogeneous test samples
A method is provided for more accurately calculating the concentration of analytes or components in test samples. The method includes the use of an algorithm for analysis, and selection of sets of...
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5836883 |
Measuring the characteristics of a scattering medium
Apparatus for measuring characteristics of a scattering medium. A light source irradiates the medium to be measured with a plurality of measurement light beams. A wavelength selector unit...
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5838429 |
Apparatus for measuring physiological parameters of blood guided in an extracorporeal circulatory system
The invention relates to an apparatus for measuring physiological parameters of blood conveyed within an extracorporeal circulatory system. Two light sources (1a, 1b) emit light of varying...
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5832921 |
Analog heater control for medical instrument
An instrument for determining a characteristic of a biological fluid or a control includes a heater and a heater control. The heater comprises a heater element, supported in heat conducting...
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5830359 |
Method of separating particles from a filter
Particles that move at low Reynolds numbers are separated from a filter material on which they are adsorbed by subjecting the filter material, in a liquid medium, to agitation of sufficient...
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5830133 |
Characterizing biological matter in a dynamic condition using near infrared spectroscopy
A method for predicting a property of biological matter, such as biological fluid, containing water, in a dynamic condition where the biological fluid may be approximated to contain two...
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5827746 |
Method to determine the sedimentation of blood and relative device
Method and apparatus to determine the sedimentation of blood. A blood sample is taken, and an anti-coagulant substance is added. The sample is homogenized. The method includes a step of measuring...
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5817007 |
Method and an apparatus for determining the content of a constituent of blood of an individual
A method and an apparatus for determining the content of a constituent of blood of an individual are disclosed. In the method a whole blood stream is extracted from a blood vessel of said...
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5817519 |
Automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples
The present invention provides a highly sensitive and accurate method and system for the discrimination and quantification of platelets in a whole blood sample using automated hematology...
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5817025 |
Method for diagnosing malignancy diseases
The method for diagnosing malignancy diseases involving analysis of blood plasma by laser correlational spectroscopy (LSC) techniques includes the steps of: preparing a weak diluted solution of...
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5804143 |
System for high-speed measurement and sorting of particles
A system for sorting particles is arranged such that the presence or absence of multiple parameters is determined for each particle in a flow of particles, and a logic condition is determined based...
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5798217 |
Method of analyzing tumor cell DNA content through tumor cell enrichment
The invention provides a method for enriching a sample in tumor cells and determining the DNA ploidy and proliferative index of the tumor cells present in the sample. The method uses a...
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5798827 |
Apparatus and method for determination of individual red blood cell shape
The present invention provides an apparatus and method to determine individual red blood cell shape within a flow cytometric aperture. Cell shape is determined by measuring the asymmetry of a light...
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5793969 |
Network review and analysis of computer encoded slides
A network system for review and analysis of computer encoded microscope slides and specimens which were originally computer encoded from a microscope (attached via an encoder device to a local...
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5792050 |
Near-infrared noninvasive spectroscopic determination of pH
Methods and apparatus for, preferably, determining noninvasively and in vitro pH in a human. The non-invasive method includes the steps of: generating light at three or more different wavelengths...
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5777215 |
Apparatus for measuring the coagulation characteristics of test liquids
An apparatus for measuring the coagulation characteristics of test liquids, in particular of blood samples, is provided. The apparatus comprises a plate (2, 20) with a bearing (3, 23) arranged in...
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5774223 |
Optical measuring method and an optical measuring apparatus for determining the internal structure of an object
An optical measuring method and an optical measuring apparatus are capable of obtaining the true mean time delay of a light waveform within a short time for the purpose of obtaining information on...
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5770454 |
Method and aparatus for determining an analyte in a biological sample
A method and apparatus for analytical determination of a concentration of an analyte in a biological sample include a series of hardware elements and method steps which perform at least two...
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5768407 |
Method and system for classifying agglutination reactions
A method and system for analyzing a solution for an agglutination pattern. The method comprises the steps of producing an illuminated image of the solution on an array of pixels, and assigning to...
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5764792 |
Method and apparatus for processing images
A method and apparatus for detecting rare cells in a biological sample is disclosed. A color image of the sample is generated and the color image is decomposed into its color components. A first...
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5759767 |
Two-photon and multi-photon measurement of analytes in animal and human tissues and fluids
A method of measuring an analyte present in animal (e.g., human) tissue or fluids such as blood or plasma. The analyte is multi-photon excitable (e.g., two-photon excitable) at a first wavelength...
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5755226 |
Method and apparatus for noninvasive prediction of hematocrit
A method and apparatus for the direct noninvasive prediction of hematocrit in mammalian blood using photoplethysmography techniques and data processing. The method and apparatus also include...
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5751839 |
Apparatus and process for the detection and counting of rarely occurring mammalian cells
Apparatus and process capable of rapid detection and counting of rarely occuring mammalian cells in blood and other tissues which have been labeled with a fluorescent dye. The process includes:...
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5746206 |
Isolated layer pulse oximetry
An apparatus of and method for measuring arterial blood oxygen saturation at a particular tissue level of interest. Visible and near infrared radiation is emitted into a patient at the measurement...
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5745227 |
Method and apparatus for determining the erythrocyte sedimentation rate
In an improved method for measuring the erythrocyte sedimentation rate (ESR) a pre-evacuated test tube (T) is used to collect a blood specimen. The tube (T) is made of a material such as glass or...
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5742380 |
Plasma assay spectrometer
A fluorescence spectrometer for determining a concentration of a photosensitizing drug in a patient, for PhotoDynamic Therapy treatment of the patient by a treatment light at a treatment light...
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5741213 |
Apparatus for analyzing blood
An apparatus for analyzing blood includes an image capturing device for capturing an image including at least one object blood cell and an analyzer for analyzing the captured image as an image F(x,...
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5740185 |
Interleaved data communications system for controlling multiple centrifuges
A centrifuge network communication system for transmitting instructions to, and receiving data from, a plurality of centrifuge instruments using a central data controller. The central data...
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5726745 |
Process and apparatus for preparing a blood sample for analysis of white blood cells
A process and apparatus for preparing blood for analysis of white blood cells involves: preparing a mixture made up of blood and a lysing agent, emitting luminous radiation in the direction...
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5719391 |
Fluorescence imaging system employing a macro scanning objective
A fluorescence imaging system that includes an objective that is both achromatic and has an external entrance pupil. The objective also serves as a condenser for the system which substantially...
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5710630 |
Method and apparatus for determining glucose concentration in a biological sample
A method for the analytical determination of the glucose concentration in a biological sample. In a detection step, light is irradiated into the sample and the light emerging therefrom after...
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5692504 |
Method and apparatus for the analysis of glucose in a biological matrix
Method and apparatus for the analytical determination of glucose concentration in a biological matrix, wherein in a detection step light from a light emitter is irradiated into the biological...
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5690105 |
Method and apparatus for determining a particle criterion and particle analyzer using the criterion
A method and apparatus for determining a particle criterion to set a predetermined region as the particle criterion in a distribution data of a particles of a specimen and to analyze the specimen...
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5690895 |
Flow cell apparatus
A flow cell apparatus, useful in an apparatus for measuring particles suspended in a liquid, comprises a sample liquid, supply device, a sheath liquid supply device, a flow cell which has a flow...
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5682038 |
Fluorescent-particle analyzer with timing alignment for analog pulse subtraction of fluorescent pulses arising from different excitation locations
A flow cytometry system includes a flow tube through which particles marked with different fluorochromes pass from a first location, illuminated by a red laser, to a second location, illuminated by...
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5677762 |
Apparatus for illumination stabilization and homogenization
An illumination device provides temporally, spatially and angularly stable illumination for microscopic evaluations. An arc lamp serves as the light source. An input optical train gathers and...
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5676143 |
Apparatus for analytical determination of glucose in a biological matrix
An apparatus for determination of a glucose concentration in a biological matrix includes an irradiation device for irradiating light as primary light into a biological matrix, and a detection...
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5670050 |
Method for detection of leakage of blood
A method for detecting the presence of blood in a dialysate solution is disclosed. The method provides for certain measurement of light intensity passing through solutions both before and during...
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RE35589 |
Biological assembly
A biological assembly for effecting the examination of a sample in a liquid medium under magnification. The assembly includes a transparent slide with a sample chamber and an immediately adjacent...
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5656501 |
Flow cell device for monitoring blood or other cell suspension under flow
A flow cell for monitoring blood or any other cell suspension under flow prises a rigid transparent base having a pair of holes with inlets and outlets. One hole transfers the cell suspension from...
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5644388 |
Imaging flow cytometer nearly simultaneously capturing a plurality of images
A sample liquid containing particles are caused to flow through a transparent flow cell. An image capturing device is used to capture different images for a single particle existing in an image...
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5632273 |
Method and means for measurement of biochemical components
Biochemical components and changes in the components are measured by directing light of several wavelengths into a body at one location, sensing light at the wavelengths emerging from the body at a...
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