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6151405 |
System and method for cellular specimen grading
The system and method for evaluating the amount of marker identifying precipitate in a cellular specimen on a microscope slide is disclosed. The automated microscope system performs a low...
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6147749 |
Method and apparatus for measuring concentration by light projection
To project measuring light with good reproducibility onto the measuring part of a measured object so that measurement conditions can always be constant. An optical measuring apparatus is equipped...
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6144444 |
Apparatus and method to determine blood parameters
The present invention relates to an apparatus for monitoring blood parameters during cardio-pulmonary bypass surgery or during other procedures which utilize an extracorporeal circuit. The...
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6130743 |
Colorimetric red blood cell sensor
A colorimetric red blood cell sensor provides an automatic system for deting and preventing the further mixing of red blood cells and plasma. The sensor includes a processor that controls blue and...
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6126612 |
Method for detecting cyanide in cutaneously transpired gas
A method of detecting cyanide concentration in the cutaneously transpired gas of a patient, allowing for the timely implementation of an appropriate treatment. Where the skin of a patient suffering...
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6124139 |
Method and apparatus for indirect agglutination immunoassay
A method of indirect agglutination immunoassay includes, allowing particles of a reagent for immunoassay to precipitate in bottoms of at least one well, inclining the well at a specified angle to...
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6118522 |
Apparatus and method for differentiating erythrocytes in urine
An apparatus for differentiating erythrocytes in urine includes: a sheath flow cell for forming a urine specimen flow by surrounding a urine specimen with a sheath liquid, the urine specimen...
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6111248 |
Self-contained optical sensor system
A self-contained optical sensor (5) with a device platform (7) and an encapsulating light transmissive housing (9) formed therein is disclosed in conjunction with several sensor configurations...
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6111636 |
Device for measuring optical density
The application relates to a device for measuring the optical density of samples arranged in strips on a plate. The device comprises a measurement head (3) moving strip by strip in relation to the...
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6103197 |
Method and apparatus for optically determining total hemoglobin concentration
In a method of optically determining the total hemoglobin concentration (tHb) in non-hemolyzed whole blood, using at least two wavelengths for measuring, a first wavelength of λ<805 nm and a...
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6100966 |
Test device for bodily fluids
A test device for bodily fluids comprising a solid carrier with a bonded reagent, a light source and a light detector. Light source and light detector are positioned is such a way that the majority...
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6101406 |
Cassette for measuring parameters of blood
A cassette useful for measuring one or more parameters of blood in, for example, a cardiopulmonary bypass circuit has a convex coupling for releasable connection with a mating, concave coupling of...
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6091483 |
Method and apparatus for preparing substances for optical analysis
A solid matter collection apparatus and a method for collecting solid matter in a fluid. The apparatus includes a collection site that collects the solid matter at a predetermined density and...
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6088087 |
Transcutaneous measurement of substance in body tissues or fluid
An apparatus and method for transcutaneous measurement of a substance within a body. Transcutaneous measurement of substances within a subjects' tissues or fluids is effected through the use of the...
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6084660 |
Initiation of an analytical measurement in blood
A distinctive optical signature permits a fluidic medical diagnostic device to measure an analyte concentration or a property of whole blood, particularly the coagulation time, only after first...
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6084661 |
Optical method and apparatus for measuring carbon monoxide in non-hemolyzed blood
Carbon Monoxide (CO) is a colorless, tasteless, and odorless gas which causes asphyxiation by combining with a strong affinity to blood hemoglobin. Unless a patient is quickly identified as having...
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6084676 |
Non-contact non-invasive measuring method and apparatus
The distance between an image indicating a measured portion and a measuring apparatus is previously registered, a measured object is arranged in a prescribed space in a non-contact state, the...
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6073037 |
Near-infrared noninvasive determination of pH in pulse mode
Methods and apparatus for, preferably, determining noninvasively and in vivo pH in a human. The non-invasive method includes the steps of: generating light at three or more different wavelengths in...
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6069687 |
Contaminant detector
A contaminant detector including a light source for emitting light of a wavelength with peak emission corresponding to that of "blue" light or to that of light of even lower wavelength. Light is...
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6064474 |
Optical measurement of blood hematocrit incorporating a self-calibration algorithm
An optical method for obtaining hematocrit values of blood uses the light transmittance properties of blood as a means of acquiring information about the blood sample. An algorithm is used to...
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6061581 |
Invasive and in vivo near-infrared determination of pH
Methods for determining invasively and in vivo pH in a human. The invasive method includes the steps of: generating light at three or more different wavelengths in the range of 1000 nm to 2500 nm;...
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6055060 |
Analytical system with means for detecting too small sample volumes
Analytical system for evaluating test elements having means of determining whether a sufficient amount of sample liquid was evenly applied to an application zone comprising in a first embodiment of...
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6043871 |
System and method for measuring blood platelet function
An instrument is described for measuring the platelet aggregation in whole blood in response to standard aggregating agents. The instrument is designed to be used in the clinical laboratory to...
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6025201 |
Highly sensitive, accurate, and precise automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples
The present invention provides a highly sensitive and accurate method and system for the discrimination and quantification of platelets in a whole blood sample using automated hematology...
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6016193 |
Cuvette holder for coagulation assay test
A cuvette holder is provided to allow a flow cell optical analyzer to be adapted for coagulation analysis. The flow cell analyzer has a light source and a photo detector defining a first and a...
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RE36474 |
Signal processing method and apparatus
A method and apparatus for the determination of spectral samples is disclosed wherein spectral measurements are taken, normalization of the spectral measurements takes place, and a bilinear...
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6005658 |
Intermittent measuring of arterial oxygen saturation of hemoglobin
Described is a method and a system for detecting the arterial oxygen saturation of hemoglobin (also called blood oxygenation, SpO2 or SaO2 measuring), comprising a measuring device for performing a...
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5995208 |
Intravascular oximetry catheter
Apparatus and a method for monitoring a percentage of the oxygen saturation in the hemoglobin of blood flowing through a blood vessel. An optical sensor that detects the percentage oxygen...
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5986770 |
Apparatus and method for the optical characterization of the structure and composition of a light scattering sample
Apparatus for the optical characterization of the internal structure and/or composition of a spatially extended, scattering sample comprising an arrangement of one or several light sources and one...
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5980757 |
Interface detection and control systems and method
A viewing area in a blood separation chamber is monitored for the presence of an interface region between plasma and cellular blood components. Sensed optical density values for the viewing area...
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5976886 |
Fluorescein bloodstain detection method
An improved method of detecting latent bloodstains using a thickened solution of fluorescin which is applied to a surface, activated by application of hydrogen peroxide and visualized as...
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5961469 |
Spectrophotometric assay for cyanide
A method of detecting and quantifying cyanide concentration in a patient, by monitoring photometric changes resulting from the transformation of methemoglobin to cyanomethemoglobin. The present...
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5963335 |
Means and method for measuring absorption of radiation-scattering samples
The present invention provides methods and devices for measuring radiation absorption by a sample. The invention enables one to determine whether the sample scatters the radiation of interest and,...
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5957841 |
Method of determining a glucose concentration in a target by using near-infrared spectroscopy
A glucose concentration in a living tissue as a target is determined by the following method. Near-infrared radiation is projected on the living tissue, and a resulting radiation emitted from the...
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5956130 |
Method of surgical fluid analysis
A monitor to provide substantially real-time estimates of fluid absorption rate and tissue loss rate in a patient during a surgical procedure. The monitor estimates fluid source flow rates and...
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5944660 |
Disposable cartridge assembly with optional integrated temperature control system, and systems containing same
A cartridge assembly is provided for analyzing characteristics of a sample fluid. The cartridge assembly comprises an assembly body having a passageway, a cavity and, interposed between the...
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5938595 |
Fiber optic D dimer biosensor
A fiber optic sensor for D dimer (a fibrinolytic product) can be used in vivo (e.g., in catheter-based procedures) for the diagnosis and treatment of stroke-related conditions in humans. Stroke is...
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5940177 |
Method and apparatus for determining the size distribution of different types of particles in a sample
A method and apparatus for determining the size distribution of at least two different types of fluorescent or fluorescently stained particles in a sample by radiating light into a stream of...
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5934278 |
Non-invasive blood analyzer
A non-invasive blood analyzer includes a light applying device for applying light to a detection region including a blood vessel in a living body and a capturing device for capturing an image of...
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5936714 |
Red blood cell spillover detection technique
An apparatus and a method are provided to monitor a generally transparent blood tube at a location that is downstream from a blood separator in order to detect the presence of red blood cells in a...
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5933226 |
Attachment for a concentration measuring apparatus and a concentration measuring system
An attachment is designed such that a concentration measuring apparatus is attachable to and detachable from it. Inside the leading end portion of the attachment, leading ends of two light guide...
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5917584 |
Method for differentiation of nucleated red blood cells
A method is provided for differentiation of nucleated red blood cells. In addition, the method provides for a concurrent differentiation of leukocytes in a blood cell sample by suitable electronic...
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5900215 |
Fiber optic sensor
A method is provided for manufacturing a fiber optic sensor for detecting or measuring a parameter of interest in a sample fluid, including pH, concentration of dissolved gases such as O 2 or CO 2...
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5898487 |
Apparatus and method for determining the concentrations of hemoglobin derivatives
An apparatus for determining the concentrations of n hemoglobin derivatives in a sample of undiluted, unhemolyzed whole blood provided in a cuvette, employs a device producing a primary light beam...
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5891029 |
Method of and device for positioning a living body for biological measurement and apparatus for measurement of biological information
To secure a highly accurate measurement value of biological information with minimized variation by positioning a target part of a living body with good reproducibility and by positioning the...
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5889585 |
Method and apparatus for the measurement of blood sugar
In an apparatus and method for detecting the concentration of a substance in a fluid, such as the concentration of sugar in blood, the measuring field of a test strip to which the fluid to be...
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5889584 |
Assembly for rapid measurement of cell layers
A sample of anticoagulated whole blood contained in a transparent tube is centrifuged so as to gravimetrically separate the various blood cell and other components by specific gravity. The tube may...
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5886252 |
Power supply monitor and control for medical instrument
An instrument for determining a characteristic of a biological fluid or a control comprises a radiation-reflective surface, a first source for irradiating the surface, a first detector for...
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5885212 |
Non-invasive measurement of blood PH
Methods and apparatus are provided for non-invasively determining blood pH by a multivariate analysis technique, such as classical least squares (CLS), partial least squares (PLS), or principal...
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5886808 |
Pulse shaping system
Temporally shaped electrical waveform generation provides electrical waveforms suitable for driving an electro-optic modulator (EOM) which produces temporally shaped optical laser pulses for...
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