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6922479 |
System and method for generating a profile of particulate components of a body fluid sample
A system for generating a profile of particulate components of a body fluid sample is provided. The system includes: (a) a device for causing controlled flow of the body fluid sample on a...
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6908593 |
Capillary flow control in a fluidic diagnostic device
A medical diagnostic device for measuring an analyte concentration or property of a biological fluid includes capillary flow channels to convey a sample of the fluid from an inlet to a branching...
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6903815 |
Optical waveguide sensor, device, system and method for glucose measurement
An optical waveguide sensor for glucose measurement comprises a substrate, a first optical waveguide layer formed on a surface of the substrate, an entrance grating and an exit grating which are...
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6898296 |
Specimen processing system
A specimen processing system according to the present invention includes a plurality of specimen processing units each having flat sides and a specimen operating surface and operated singly. The...
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6888951 |
Methods and apparatus for analyzing operational and analyte data acquired from optical disc
Methods and apparatus for analyzing nonoperational data acquired from optical discs, and in particular, trackable optical discs having concurrently readable nonoperational structures are provided....
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6879713 |
Meiotic spindle imaging in oocytes and uses therefor in in vitro fertilization
The developmental potential of a mammalian oocyte for successful implantation is evaluated by producing a plurality of intensity images of the oocyte using polarized light optics, and calculating a...
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6873719 |
Image acquisition apparatus
Image acquisition apparatus is used to obtain images of contents of containers for use in, for example, antibiotic susceptibility testing. The apparatus has image capture means, such as a scanner (...
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6871169 |
Combinative multivariate calibration that enhances prediction ability through removal of over-modeled regions
A novel multivariate model for analysis of absorbance spectra allows for each wavelength or spectral region to be modeled with just enough factors to fully model the analytical signal without the...
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6864716 |
Reconfigurable memory architecture
A pre-diffused high density array of core memory cells is provided in a metal programmable device. The peripheral logic is made up of gate array cells in the metal programmable device. The...
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6853857 |
Method, device and computer program for determining the blood flow in a tissue or organ region
In a method, a device and a computer program for determining the blood flow in a tissue or organ region, the fluorescence intensity of an exogenous chromophore is measured as a function of time in...
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6847451 |
Apparatuses and methods for analyte concentration determination
Apparatuses and methods for determining the concentration of an analyte in a physiological sample are provided. The subject apparatuses include at least one light source, a detector array, means...
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6842233 |
Method of classifying particles on two-dimensional frequency distribution map and blood analyzer utilizing the same
A method of classifying particles indicated on a two-dimensional frequency distribution map into particle clusters, includes the steps of: dividing the particles into a first cluster and a second...
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6831733 |
Analysis method and system therefor
The invention concerns a method for quantitative hemoglobin determination in undiluted, unhemolyzed whole blood comprising the steps of: providing a disposable, capillary, which has an optical...
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6825918 |
Method and apparatus for measuring blood sugar
In a method for the measurement of the concentration of a substance in a liquid, especially for blood sugar measurement, the liquid to be measured is applied to the measuring field of a test strip,...
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6819408 |
Method for obtaining a monolayer of desired particles in a liquid sample
The present invention relates to a method and apparatus for analyzing a blood or other biological fluid sample in a quiescent state without the need for additional diluting reagents or fluid...
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6816241 |
LED light source-based instrument for non-invasive blood analyte determination
A compact, lightweight instrument for non-invasive blood analyte determination employs a light source incorporating an assembly of LED's interconnected within a thermally stable substrate. A large...
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6813009 |
Detection of metabolic dysfunctions using fluorescence emission from serum
Serum emission can be used as the first test to detect metabolic disorders in mammals. When changes in emission of the serum from patients with different pathological conditions were characterized,...
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6806947 |
Apparatus for monitoring a fluid conduit
Apparatus and methods for determining the presence of a fluid conduit at a predetermined location and at least one characteristic of the fluid in the conduit are disclosed. The apparatus includes a...
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6794194 |
Method for measuring hemoglobin concentration (HGB) in the blood in a circuit of a dialysis machine, measuring device and circuit for the application of the method
A method for measuring the hemoglobin concentration in the blood in a circuit of a dialysis machine includes directing electromagnetic waves against one section of the circuit, measuring values of...
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6791674 |
Analytical method and apparatus for blood using near infrared spectroscopy
A method of analyzing blood using a near infrared apparatus, in which monochromatic near infrared light in a wavelength range of 700 nm-1100 nm from the slit of the near infrared apparatus is...
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6770883 |
Sample level detection system
A method and apparatus for detecting the level of red blood cells, plasma or serum, and organic separation gel in a test tube covered with multiple labels is provided. Visible and infrared light...
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6749565 |
Method for blood infrared spectroscopy diagnosing of inner organs pathology
A rapid diagnosis method for organ specific disease state is based on obtaining an infrared absorbance spectra of a patient's blood at a frequency range from about 400 cm −1 to about 2000 cm...
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6731379 |
Method and device for determining the concentration of heparin in a sample of fluid
A device for determining the concentration of heparin in a fluid sample comprising: a container for holding the fluid sample; a container for holding the dye solution; a mixer for mixing the fluid...
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6717657 |
Apparatus for measuring the volume of individual red blood cells
The invention discloses an apparatus and a method for determining the volume of individual red blood cells or other particles that are suspended in liquids. The sample is disposed into an optical...
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6714287 |
Apparatus for determining the volume of single red blood cells
The invention discloses a method and apparatus for determining the volume of single red blood cells or other particles that are suspended in liquids. The sample is disposed into an optical cuvette...
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6707554 |
Method for the photometric analysis of test elements
The invention concerns a method for the photometric analysis of test elements with a detection zone which is stable towards positioning tolerances of the detection zone comprising the following...
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6692967 |
Method and compositions for detecting of bloodstains using fluorescin-fluorescein reaction
A method, compositions and kit are set forth for detecting blood stains. A reactant solution includes fluorescin solubilized (reduced) in acetic acid in ethanol. The solution may be buffered to a...
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6694157 |
Method and apparatus for determination of pH pCO2, hemoglobin, and hemoglobin oxygen saturation
This invention relates to a method and apparatus for in-vivo, real time measurement of pH, pCO 2 , base excess, hemoglobin, and hemoglobin oxygen saturation. Specifically, the invention relates to...
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6678040 |
Apparatus for measuring number of cells
A number-of-cells measuring apparatus for measuring the number of cells contained in a liquid including cells comprises an input section for inputting information of a size of said pre-measured...
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6674525 |
Split focusing cytometer
A microcytometer which combines lysing and cytometry into a unified system that achieves blood lysis and white blood cell count in a single device. The device focuses the white cells into a thin...
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6670191 |
Method for quantitatively analyzing fragmented red blood cells
A method for quantitatively analyzing fragmented red blood cells includes the steps of: preparing a two-dimensional particle distribution diagram on the basis of a scattered light intensity and...
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6661501 |
Cytological stain composition including verification characteristic
The present invention relates to the analysis of cytological material. Specifically, the invention relates to stains and methods of producing the stains, methods of staining cells for cytological...
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6661909 |
Calibration of fluorescence resonance energy transfer in microscopy
Imaging hardware, software, calibrants, and methods are provided to visualize and quantitate the amount of Fluorescence Resonance Energy Transfer (FRET) occurring between donor and acceptor...
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6660995 |
Particle size analysis in a turbid media with a single-fiber, optical probe while using a visible spectrometer
Apparatus and method for measuring scatterer size in a dense media with only a single fiber for both light delivery and collection are disclosed. White light is used as a source and oscillations of...
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6633369 |
Method for measuring the volume of individual red blood cells
The invention discloses a method for determining the volume of individual red blood cells or other particles that are suspended in liquids. The sample is disposed into an optical cuvette suitable...
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6633368 |
Method for determining the volume of single red blood cells
The invention discloses a method for determining the volume of single red blood cells or other particles that are suspended in liquids. The sample is disposed into an optical cuvette suitable for...
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6630990 |
Optical method and apparatus for red blood cell differentiation on a cell-by-cell basis, and simultaneous analysis of white blood cell differentiation
Methods and apparatus are disclosed for determining the volume, hemoglobin concentration, maturity and cell shape of mammalian red blood cells in a whole blood sample and simultaneously monitoring...
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6624882 |
Methods of sampling body fluid
A sampling apparatus for sampling body fluid includes a sampler having an external geometry selected to mate with an internal geometry of a testing apparatus such that the sampler may be inserted...
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6621917 |
Device and method for examining biological vessels
The present invention pertains to a device for examining biological vessels, especially retinal vessels, including an evaluation unit in the form of an image manipulator (BM) enabling at least...
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6603552 |
Portable system for detecting skin abnormalities based on characteristic autofluorescence
A lightweight hand-held skin abnormality detection system includes a source of excitation light that causes tissue under examination to produce fluorescence light. The fluorescence light produced...
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6597438 |
Portable flow cytometry
A portable or wearable cytometer that can be used at remote locations, such as in the field or at home. The flow cytometer of the present invention may help improve the healthcare of many weak,...
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6587203 |
Sort stream stabilizer for flow cytometer
A flow cytometer includes a temperature regulator that maintains the temperature of the piezoelectric actuator sufficiently constant so as to produce a consistent predetermined oscillation...
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6579722 |
Chemiluminescence chemical detection of vapors and device therefor
A solid phase chemical sensor includes a polymer film which has a chemiluminescent reagent immobilized therein. The polymer film and chemiluminescent reagent are chosen to significantly enhance the...
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6576106 |
Method for separating and assaying lipoprotein, an assembly for performing such a method, and a system including such an assembly
A method for separating and assaying lipoprotain to determine a degree of modification of a predetermined component in a specimen of lipoprotein, comprising the step of: determining a distance...
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6563585 |
Ratiometric fluorometer
A method and apparatus for measuring the concentration of various analytes in a sample using native fluorescence is described. A first light source for producing a first light having a first...
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6564076 |
Time-resolved spectroscopic apparatus and method using streak camera
Methods and apparatus using the principles of time-resolved spectroscopy are disclosed. The present invention employs incident light pulses of sufficiently short duration to permit the rate of the...
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6549661 |
Pattern recognition apparatus and pattern recognition method
Recognizable data storage apparatus stores an image feature parameter of an object and its classification result for those objects for which said classification results are evaluated as having high...
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6549275 |
Optical detection system for flow cytometry
An optical detection system for flow cytometry that uses two or more light sources positioned laterally at different distances from the central axis of the flow stream for providing light through...
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6542762 |
Near-infrared noninvasive determination of pH in pulse mode
Methods and apparatus for, preferably, determining noninvasively and in vivo pH in a human. The non-invasive method includes the steps of: generating light at three or more different wavelengths in...
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6532061 |
Measuring the velocity of small moving objects such as cells
Frequency domain velocity measurements and time domain velocity measurements are made using light from cells or other objects. An optical grating is used to modulate the light from an object so...
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