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4476231 |
Method of analyzing the distribution of a reagent between particles and liquid in a suspension
In an immunoassay procedure, an analyte in a solution is reacted with a reagent with a label. The reagent is segregated into solid phase (particles) and liquid phase (liquid) with the unreacted...
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4469398 |
Optical connector for use during photometric analysis
An optical connector for connecting photometric analysis equipment which includes a transmitting and receiving light pipe to a material such as flowing blood wherein the blood is not contaminated...
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4466740 |
Particle agglutination analyzing plate
A plate for use in an immunological analysis on the basis of agglutination reaction of particles, has formed therein a number of reaction vessels each having a conical bottom surface. The plate is...
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4454752 |
Test circuit for use in coagulation instrument
In a photometric coagulation instrument a synthetic clot signal is generated so that the operation of the instrument can be checked without the need to measure the actual clotting time of a control...
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4455376 |
Photometric methods for counting the particulate components of blood
Photometric apparatus, for counting the particulate components in blood and for determining the degree of particulate agglutination, which comprises a cuvette for holding a blood bearing solution...
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4453266 |
Method and apparatus for measuring mean cell volume of red blood cells
An apparatus and method are provided for producing signals representative of the mean cell volume of red blood cells in a blood specimen. The apparatus includes means for generating signals...
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4452759 |
Immunological agglutination pattern detection device
An immunological agglutination pattern detection device, which can precisely detect an agglutination pattern formed on the base surface of a reaction vessel and which is simple in construction and...
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4428669 |
Method and device for measuring the deformability of living cells, notably of red blood corpusles
In order to produce easily a deformation in a cell population enabling the production of an optical diffraction pattern, a liquid containing a suspension, either homogeneous, or localized, is...
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4412004 |
Method for treating red blood cells to effect sphering and reagent therefor
A method is disclosed of blood serum sample preparation for improved, more accurate and precise, electro-optical method for measuring erythrocyte volumes, individually and as an average.
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4411518 |
Apparatus for use in qualitative determination of immunological reactions
An apparatus is provided for use in qualitative and quantitative determinations of agglutination in immunoreactive systems. The apparatus comprises a carriage assembly having a plurality of spaced,...
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4408877 |
Device for hydrodynamic focussing of a particle-suspension in a liquid flow cytophotometer
Device for liquid flow cytophotometer including a device for hydrodynamic focussing (4,6) of a cell- or particle-suspension towards a measuring area, and an optical excitation-and detection-system...
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4388824 |
Process and an apparatus for testing the coagulation properties of liquids
The coagulometer for measuring the clotting time of liquids such as blood has a turning sample vessel whose axis of turning is at an angle to the vertical. Within the vessel an annular space is...
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4374644 |
Blood cell volume monitoring
By subjecting cells, such as red blood cells, to a hypotonic solution or a solution having a lytic agent, the cells will rapidly attain a change in volume and electrical resistance parameters,...
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4354114 |
Apparatus for investigation of fluorescence characteristics of microscopic objects
A fluorescence microscope with a movable stage has means to stop stage movement when a modified object, such as an abnormal cell, is detected. A beam-splitting plate with an interference coating is...
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4352558 |
Apparatus for measuring particle characteristics
In apparatus for measuring reaction and/or diffusion of particles suspended in a fluid, which apparatus includes a supply tube for supplying a stream of the particle-containing fluid, a tapered...
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4352557 |
Determining a test value corresponding to blood subsidence
A test value corresponding to blood subsidence from a syllectogram is determined as a result of the effect of shearing forces on a blood sample, by ascertaining the slope of the test curve...
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4343782 |
Cytological assay procedure
Disclosed is a method ofbioassay based on the detection of changes in the membrane potential of individual cells. A cell suspension is incubated with a solution of a substance capable of affecting...
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4341757 |
Stable isotopic immunoassay method employing non-radioactive selenium label
There is disclosed a "cold", i.e., non-radioactive (stable) isotope method for the immunoassay of biological compounds. The method uses selenium as the tracer label in compounds which compete in...
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4338024 |
Flow analyzer and system for analysis of fluids with particles
The method and apparatus for analyzing particles and particularly blood cells by conveying the particles along a broad shallow path where the path is magnified and converted into a series of still...
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4332472 |
Automatic cataphoresis apparatus
An apparatus for automatic cataphoresis comprises means for feeding a blood serum bearing film; a cutter for cutting the film to a given length; means for supplying a buffer solution for wetting...
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4332788 |
Method of determining an antigen, antibody for antigen-antibody complex including fixing the aggregates thereof
A method for the quantification of an antigen, antibody, or antigen-antibody complex in a sample solution involving measuring the results of an immunochemical agglutination reaction or an...
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4331132 |
Angioscope
In an angioscope for observing the condition of a blood vessel, a microscope comprises an optical system for forming a blood vessel or vascular image illuminated by a reflecting illumination device...
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4325706 |
Automated detection of platelets and reticulocytes in whole blood
A sample of whole blood is stained with an acridine orange reagent, and is analyzed rapidly, a cell at a time, in a flow cytometry system having a sample stream dimension in the range of expected...
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4318886 |
Automatic HLA typing apparatus
Apparatus for automatically typing HLA (Human Leukocyte Antigen) is disclosed. An optical image of a sample containing lymphocytes is formed by a phase-contrast microscope. The optical image is...
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4313735 |
Automatic chemical analyzing method and apparatus
A train of cuvettes are held on a turntable and serum specimen is sequentially sampled each time the turntable makes a revolution through more than 360°. While the turntable is at rest, blank...
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4312728 |
Method for determining boundary points on electrophoretic densitograms
A method for determining boundary points on electrophoretic densitograms comprising a bounding point judging step for locating boundary points on electrophoretic densitograms, a normal fraction...
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4311394 |
Automatic analytical apparatus
An automatic analytical apparatus for effecting quantitative analysis of a given substance contained in a sample such as blood, urine or the like and comprising a sample holding and carrying means...
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4306877 |
Optical measurement of concentration
The concentration of a substance of interest is measured by exposing a peable-membrane face of an indicator chamber containing an indicator to the substance, monochromator radiation being incident...
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4307376 |
Pattern recognition system for generating hematology profile
A system is disclosed for generating a maturity index for blood cells which may be used in a hematology profile to show the health of a patient. The system includes a scanning system for scanning a...
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4304488 |
Blood oxygen analyzer
A method and system for measuring the oxygen carrying capacity of normal and abnormal hemoglobins and red cells under controlled pH, ionic strength, temperature and gas conditions is described. A...
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4303336 |
Method and apparatus for making a rapid measurement of the hematocrit of blood
The method includes the steps of: placing blood in a transparent tubing; passing intense, coherent light through the tubing and blood; sensing the light passed through the tubing and blood; and,...
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4287087 |
Fixed-dried blood platelets
Screening tests and bioassay of von Willebrand's factor (platelet aggregating factor) in human and animal blood plasma are effected using a reagent of blood platelets and snake venom having a...
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4284412 |
Method and apparatus for automated identification and enumeration of specified blood cell subclasses
Specified subclasses of blood cells, such as of lymphocytes, are automatically identified based on utilization of antigenic determinants on the cell surface, their reactivity with antibodies which...
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4284355 |
Automated method for cell volume determination
Fluorescence volume exclusion signals are utilized to evaluate cell volume. Cells are suspended in a medium which is furnished with a fluorescent dye which neither penetrates nor adheres to the...
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4279616 |
Method for measuring blood coagulation and device therefor
A method and apparatus is disclosed for measuring blood coagulation factor, operating on the principle wherein the clotting time (T) of a sample of blood to which a reagent has been added is...
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4279506 |
Photometric apparatus and methods for counting the particulate components of blood
Photometric apparatus, for counting the particulate components in blood and for determining the degree of particulate agglutination, which comprises a cuvette for holding a blood bearing solution...
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4274453 |
Aseptic fluid transfer
The combination of an automated hematology analyzer (21) with an input device (20) enabling closed transfer of blood to said analyzer to a sealed specimen container having a perforable closure, and...
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4269516 |
Optode
Monochromatic excitation light penetrates an indicator in an indicator sp. The indicator space is closed off at the side to be brought into contact with the substance to be analyzed by means of a...
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4263512 |
Colorimetric method for liquid sampler including disturbing chromogens
Color former is added to blood serum sample color it, and measurements for specific components are determined based on the light absorbance caused by coloring. For one sample, a differential light...
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4259012 |
Blood count reader
An apparatus for determining hematocrit, white cell and differential white cell and platelet counts in a centrifuged sample of blood contained in a transparent tube, preferably of capillary size....
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4255788 |
Phasing detector for continuous flow systems
A phasing system is provided for parallel channel continuous flow systems wherein the individual test channels have different flow times although intersample timing is constant. A phasing sample is...
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4252536 |
Method and system for measuring blood coagulation time
A blood coagulation time measuring method comprising irradiating a mixture of blood plasma and reagent with a beam of specified amount of light, detecting changes in the amount of light scattered...
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4252438 |
Measurement of relative movement between two phases
For measuring the speed of movement of one phase in another, and particularly the rate of sedimentation of corpuscles in blood plasma, a container is filled with a blood sample, a light beam is...
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4251750 |
Fluorescent lamp for use in liquid analysis
A fluorescent lamp contains a blend of phosphors to provide predetermined minimum power levels of radiation at predetermined spectral bands that are used in the analysis of liquid samples placed...
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4247162 |
Rectilinear drive apparatus
Rectilinear drive apparatus for rapidly and accurately moving a driven component to a desired location with settling of vibration to be achieved immediately after reaching said location; including...
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4244803 |
Quantitative protein analysis by immunodiffusion
Methods and apparatus are described by which immunochemical procedures such as immunodiffusion and immunoelectrophoresis can be used to provide quantitative measurement of the concentration of...
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4243318 |
Fluorescence analysis of stained particles
In fluorescence analysis of multiply stained particles, particularly biological cells, in a continuous flowthrough procedure, in which the particles are suspended in a carrier fluid, the carrier...
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4242730 |
Single scan microprocessor-controlled densitometer
A microprocessor-controlled densitometer system for optically scanning a blood sample or the like and generating an electric analog signal which is a function of the optical density of the scanned...
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4242194 |
Apparatus for spectroscopic measurement of the velocity of particles in a fluid
In electrophoretic apparatus measuring the velocity of particles in a fluid, a reference beam and a scattered beam scattered by the particles in the fluid at various scattering angles must be...
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4232970 |
Apparatus for automatic diagnosis of cells
An apparatus for automatic diagnosis of cells comprises a microscope, a scanning stage on the microscope, a sample carrier used to feed a sample to the scanning stage automatically, an automatic...
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