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7545496 |
Support with a surface structure for sensitive evanescent-field detection
A support structure, such as an optical disc, is designed having surface structures formed on one or more surfaces of the support to enable formation of evanescent fields in a medium adjacent to...
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7528398 |
Fluorescence imaging method and apparatus utilizing a fixed excitation source
An imaging section is secured to a casing, and an object is supported on an object support section, which is located within the casing. The object support section is moved within the casing in...
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7518727 |
Multicapillary multilaser detection system
A system for detecting electromagnetic radiation from samples comprising: a plurality of sample volumes, each of said sample volumes confined within a portion of a capillary column; a plurality of...
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7513984 |
Capillary array electrophoresis apparatus
When irradiating laser beam from the side face of the capillary array, an optical axis of the laser beam is inclined in vertical direction with respect to a plane face formed by the capillary...
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7486396 |
Electrophoretic system with multi-notch filter and laser excitation source
Apparatus and methods for detecting analytes in a sample are provided. The apparatus can include: one or more channels having a detection zone; one or more irradiation sources disposed for...
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7468793 |
Time-delay integration in electrophoretic detection systems
An apparatus for detecting analytes in a sample is provided. The apparatus includes: one or more channels having a detection zone; one or more irradiation sources disposed for irradiating the...
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7449097 |
Electrophoretic mobility measuring apparatus
The present invention provides an electrophoretic mobility measuring apparatus capable of conducting measurement with high sensitivity with optical attenuation reduced by incidence of light through...
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7428047 |
Time-delay integration in a flow cytometry system
An apparatus for detecting analytes in a sample is provided. The apparatus can include: a flow cytometry system including one or more detection zones; one or more irradiation sources disposed for...
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7384781 |
Sensors for biomolecular detection and cell classification
A sensor device is provided for detecting an analyte in a sample in which an analyte is bound to a detection reagent to form a bound complex. The device comprises (a) a sample ( 5 ) comprising an...
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7365847 |
Method and apparatus for automated excision of samples from two-dimensional electrophoresis gels
A system for automated excision of one or more samples from a sample media, including by using a device for electronically capturing one or more traits of samples in the media, using a...
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7329333 |
Uniform laser excitation and detection in capillary array electrophoresis system and method
A capillary electrophoresis system comprises capillaries positioned in parallel to each other forming a plane. The capillaries are configured to allow samples to migrate. A light source is...
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7295311 |
Methods and apparatus for electrophoretic mobility determination using phase light scattering analysis
An apparatus and method are disclosed for determining electrophoretic mobility using scattering light phase analysis comprising emitting a laser light along a path and transmitting a first portion...
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7262857 |
Device for measuring immunochromatography test piece
A measuring device 1 for immunochromatographic test strip 5 a is configured to irradiate measurement light onto the immunochromatographic test strip 5 a and to measure light from the...
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7262847 |
Optical assembly and method for detection of light transmission
An optical assembly comprising a light source, at least one sample vessel and a detector. The detector comprises a plurality of detector locations and the vessel comprises a wall and core of...
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7259849 |
Optical system for micro analyzing system
There is provided an optical system 8 for a micro analyzing system capable of precisely analyzing a sample. In the optical system 8 , after light beams leaving the tip of an optical fiber 14 ...
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7250099 |
Optical detection alignment coupling apparatus
An apparatus for aligning a capillary column with one or more excitation fibers and with one or more optical lens elements for Capillary Electrophoresis. The apparatus includes two identical blocks...
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7250098 |
Multi-capillary array electrophoresis device
An electrophoresis apparatus includes a multi-capillary array having a liquid or solid disposed between the capillaries of the array. The liquid or solid exhibits a refractive index higher than...
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7158227 |
Laser-induced fluorescence analysis device and separation apparatus comprising same
A laser-induced fluorescence analysis device ( 1 ), comprising a tube ( 2 ) including a channel, elements projecting an excitation light ( 13 ), optical collecting member ( 7 ), optical measurement...
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7139074 |
Optical system and method for optically analyzing light from a sample
An optical system for analyzing light from a plurality of samples is provided. The optical system includes a plurality of holders adapted to have samples located therein, a collection lens, a...
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7136161 |
Component analyzing apparatus with microchip
A component analyzing apparatus includes a microchip having a fine separating flow path for separating components when a sample solution labeled with fluorescence passes therethrough. A light...
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7074583 |
Method for identifying phosphoprotein
A method for identifying phosphoprotein, which comprises: subjecting a sample protein to two-dimensional electrophoresis; dephosphorylating the sample protein with phosphatase; once again...
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7054004 |
Capillary array and capillary array photodetector
A multi-focus capillary array that can reduce crosstalk and a capillary array photodetector are provided. On a substrate 20 on which a plurality of capillaries are aligned, a perforation 72 is...
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7029562 |
Capillary array electrophoresis apparatus
The electrophoresis apparatus has plural capillaries for separating fluorephore-labeled samples by electrophoresis, fluorescence detecting parts provided in a part of these capillaries arranged in...
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7019831 |
Separation device substrate including non-fluorescent quencher dye
A device is provided for the analysis of samples. The device includes a plurality of sample-containment features and a non-fluorescent quenching material for minimizing cross-talk between optical...
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6984525 |
Method for automated isolation of fractions in multichannel separation systems
A method to collect a plurality of target zones from a plurality of channels. The method includes introducing a plurality of compound mixtures into a plurality of microchannels on a microfabricated...
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6943031 |
Simultaneous chemical separation and surface-enhanced Raman spectral detection using metal-doped sol-gels
Sol-gel beds and deposits are utilized for SERS analysis of liquid analytes. The use of the same medium to both separate the chemicals and also for SERS greatly reduces the complexity of such...
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6891618 |
Optical instrument and process for measurement of samples
The present invention relates generally to the field of biochemical laboratory. More particularly the invention relates to the improved and more accurate instrumental features of equipment used as...
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6888628 |
Energy beam guide for an electrophoresis system
The energy beam guide comprises a first region having a first refractive index, the first region having an energy beam receiving end and an inclined first boundary opposing the energy beam...
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6885440 |
System and method for detecting and classifying biological particles
A continuous wave laser excites a biological particle. Detection channels are created to detect light scattered by the biological particle, and to detect any auto-fluorescence emitted by the...
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6879399 |
Measuring method for immunochromatographic test strip
A measuring device includes an irradiation optical system and a detection optical system. The irradiation optical system includes a light-emitting element and a mixing rod. The detection optical...
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6870165 |
Multi-color multiplexed analysis in a bio-separation system
A multi-channel and multi-color bio-separation detection method and apparatus in which a single detector is coupled to a plurality of radiation sources, in a one detector/many radiation sources...
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6849461 |
Method and device for the selective withdrawal of components from complex mixtures
The method according to the invention permits a selected withdrawal of one or a few molecularly disperse or cellular components of a system, such as molecules, molecular complexes, vesicles,...
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6833919 |
Multiplexed, absorbance-based capillary electrophoresis system and method
A multiplexed, absorbance-based electrophoresis system for analyzing multiple samples simultaneously without use of a mask or slit comprising a light source, a planar array of capillary tubes and a...
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6828567 |
Optical detection in a multi-channel bio-separation system
A multi-channel bio-separation detection method and apparatus in which a single detector is coupled to a plurality of radiation sources, in a one detector/many radiation sources configuration. Each...
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6809810 |
Detection cell
The detection cell includes a substrate that defines a cavity. The cavity has a substantially planar floor and at least one wall with an opening there through. The detection cell also includes a...
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6798509 |
Methods and instruments for fluorescence detection
The disclosed invention provides methods and instruments for fluorescence detection making it possible to separate and detect analytes of a plurality of species in a migration (separation) channel...
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6790671 |
Optically characterizing polymers
The invention relates to new systems, methods and products for analyzing polymers and in particular new systems, methods and products useful for obtaining sequence information from polymers. The...
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6680208 |
Rapid protein identification using antibody mixtures
A method and device is disclosed for rapidly identifying a large number of proteins by placing a protein mixture in a sample chamber of an electrophoresis gel, and performing electrophoresis to...
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6661510 |
Device for detection of fluorescent species
A device for detection of one or several fluorescent species, said species being contained in a medium, said medium being contained in a conduit, said device comprising a means of exciting the...
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6636535 |
Laser apparatus
A laser apparatus which has a laser resonator 2 for emitting a laser beam 8 , an optical fiber 23 , on which the laser beam 8 transmitted from the laser resonator 2 through a beam...
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6613212 |
Multiple capillary electrophoresis systems
The invention concerns a multiple capillary electrophoresis system including many juxtaposed capillaries, at least one source for transmitting a beam designed to excite the molecules present in its...
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6613209 |
Toner characterization cell
A toner characterization cell used to determine characteristics of insoluble particles in a liquid medium. First and second electrode are spaced apart and an electric field is applied between the...
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6608680 |
TDI imaging system for kinetic studies
Light from an object such as a cell moving through an imaging system is collected, and imaged onto a time delay integration (TDI) detector, producing a pixelated output signal in response to the...
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6592733 |
Capillary electrophoresis devices incorporating optical waveguides
A capillary electrophoresis device having a substrate layer and a cover layer, with a plurality of electrophoresis channels formed in the substrate layer, includes an optical waveguide system that...
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6590653 |
Rapid detection of species bands in a separation conduit
The present invention provides a microfluidic system for fast, accurate and low cost electrophoretic analysis of materials in the fields of chemistry, biochemistry, biotechnology, molecular biology...
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6576108 |
DNA detector and DNA detection method
An electrophoresis apparatus includes an optical cell having an outlet for fluid and filled with a buffer solution, and a plurality of electrophoresis lanes, each including a separation medium,...
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6576106 |
Method for separating and assaying lipoprotein, an assembly for performing such a method, and a system including such an assembly
A method for separating and assaying lipoprotain to determine a degree of modification of a predetermined component in a specimen of lipoprotein, comprising the step of: determining a distance...
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6554986 |
Capillary array electrophoresis scanner
An improved rotary confocal fluorescence scanner capable of detecting analytes separated on over a 1,000 capillaries simultaneously. This system uses a confocal microscope objective and mirror...
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6542691 |
Glass capillary array for fluorescence analysis and manufacturing method thereof
A glass capillary array for fluorescence analysis is provided which is capable of preventing reduction of the transmittance of a laser beam through the glass capillaries during electrophoretic DNA...
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6533912 |
Increased throughput analysis of small compounds using multiple temporally spaced injections
The apparatus and method of the present invention disclose a system in which multiple injections may be made into a capillary array. The injections are spaced in time with each injection followed...
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