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6770488 Practical method and apparatus for analyte detection with colloidal particles  
A colloidal system for detection of a variety of analytes involves techniques which permit reconstitution of a desiccated substance such as for surface enhanced Raman spectroscopic analysis and...
6766184 Methods and apparatus for diagnostic multispectral digital imaging  
Methods and apparatus for generating multispectral images of tissue. The multispectral images may be used as a diagnostic tool for conditions such as cervical cancer detection and diagnosis....
6762415 Vacuum chamber with recessed viewing tube and imaging device situated therein  
A vacuum chamber includes chamber walls separating a chamber interior and a chamber exterior, with one or more access ports defined in the chamber walls. A viewing tube extends from the chamber...
6762835 Fiber optic laser-induced breakdown spectroscopy sensor for molten material analysis  
A fiber optic laser-induced breakdown spectroscopy (LIBS) sensor, including a laser light source, a harmonic separator for directing the laser light, a dichroic mirror for reflecting the laser...
6762836 Portable laser plasma spectroscopy apparatus and method for in situ identification of deposits  
A portable Laser Plasma Spectroscopy (LPS) system and process is provided for performing in situ, near-real time, remote elemental analysis and identification of deposits or other foreign material...
6760105 Method and apparatus for inspecting DNA and method for detecting fluorescence  
A DNA sample added with a plurality of fluorescent marks is irradiated with excitation lights having a plurality of wavelengths and when fluorescence intensities are detected separately, the...
6755074 Liquid chromatographic method and system  
To economically perform preparatory chromatography, a plurality of pumps each having a corresponding one of a plurality of pistons and a corresponding one of a plurality of cylinders are driven by...
6753957 Mineral detection and content evaluation method  
A system and method for online, essentially instantaneous analyses of ore compositions on a moving belt use laser-induced break-down spectroscopy (LIBS), wherein intensity ratios of emission lines...
6750963 Imaging systems for signals on a surface  
Apparatus and methods are disclosed for imaging surfaces that comprise a sample. One embodiment of the present invention is an imaging apparatus comprising a holder for a surface, a light source...
6744503 Monitoring of vapor phase polycyclic aromatic hydrocarbons  
An apparatus for monitoring vapor phase polycyclic aromatic hydrocarbons in a high-temperature environment has an excitation source producing electromagnetic radiation, an optical path having an...
6741345 Method and apparatus for in-process liquid analysis by laser induced plasma spectroscopy  
A method and apparatus for spectrochemical analysis of liquids, including molten metals, using laser-induced plasma spectroscopy. The apparatus preferably comprises a high power pulsed laser...
6741347 Apparatus for laser flash photolysis  
An apparatus for flash photolysis has a light source and an optical fiber for directing light from the light source and through a sample. A laser or other such device is provided for initiating a...
6741344 Method and apparatus for detection of fluorescently labeled materials  
Fluorescently marked targets bind to a substrate 230 synthesized with polymer sequences at known locations. The targets are detected by exposing selected regions of the substrate 230 to light from...
6741346 Method for detecting fluorescence phenomena in microscope  
Process for detecting the phenomenon of fluorescence in a microscope, wherein the sample is irradiated by a modulated and/or pulsed laser light source, and the fluorescence is detected at least in...
6734963 Development of a compact Raman spectrometer for detecting product interfaces in a flow path  
The present invention relates to a method and apparatus for detecting transitions between different gas or liquid products in a flow path and, more particularly, it relates to an apparatus and...
6734423 Pulsed laser sampling for mass spectrometer system  
A mass spectrometer system comprising a laser and a mass spectrometer. The mass spectrometer has a vacuum interface that provides entrance of a gaseous sample into an extraction region of the mass...
6734965 Optical patternation method  
To measure property-specific distributions like surface area and mass concentrations, in a particle field that attenuates light passing therethrough, such as a spray or aerosol, a probe beam having...
6723554 Apparatus and method for measuring optical properties by feedback control  
The invention concerns an apparatus and a method for measuring at least one optical characteristic, which can include in particular turbidity (T), absorbance (A) and fluorescence (F), of a medium...
6717662 Arrangement for determining the position of a light source  
An arrangement for determining the position of a light source includes a light-sensitive detector device and an arrangement for casting a shadow onto part of the light of the light source shining...
6717667 Optical food oil quality sensor  
An instrument for measuring reliably and instantaneously the chemical quality of cooking oil, and for distinguishing between color changes due to chemical changes and color changes due to the...
6714297 Light detecting optical device  
A fluorescing molecule is bound to an microscopic slide (24). The microscopic slide (24) is coupled to a first end face of an optical waveguide (1) by means of an immersion oil. The optical...
6713260 Methods of identifying compounds that bind to target species under isothermal denaturing conditions  
The present invention provides a method for identifying a test compound that binds to a target species. The method includes: incubating at least one test mixture under isothermal denaturing...
6713019 Flow cytometer  
A flow cytometer includes a flow cell for flowing a sample liquid in a flowing direction, to form a sample flow the sample liquid containing particles to be analyzed, a laser diode radiating a...
6704104 Multi-wavelength array reader for biological assay  
The present invention relates to an array reader having a light source configured to emit an excitation light, a substrate comprising a plurality of sites spatially configured as a two-dimensional...
6693709 Photometric device  
The present invention relates to a photometric device for measuring optical parameters. The invention functions in the ultraviolet light range through use of a monochromator and splits the test...
6692974 Analytical apparatus  
A surface plasmon resonance apparatus for detecting a soluble analyte (e.g. a protein) or a particulate analyte (e.g. a cell), the apparatus comprising: (a) a sensor block adapted to receive a...
6674058 Apparatus and method for focusing a laser scanning cytometer  
The invention relates to a method and system for focusing a laser scanning cytometer. In the illustrative embodiment, during one cytometric measurement process, a single laser is used for focusing...
6665061 Method and device for detecting variations of optical properties in a sample in and analysis process  
The invention concerns a method which consists in performing for a time interval ranging between 1 ms and 10 ms a first turbidimetric measurement using a first light pulse originating from a first...
6661510 Device for detection of fluorescent species  
A device for detection of one or several fluorescent species, said species being contained in a medium, said medium being contained in a conduit, said device comprising a means of exciting the...
6661511 Method and apparatus for enhanced laser-induced plasma spectroscopy using mixed-wavelength laser pulses  
A sample of heterogeneous material is analyzed by directing a mixed-wavelength laser pulse at the sample to produce a plasma. The mixed wavelength pulse contains both shorter and longer wavelength...
6657720 Spectrometer attachments and phosphorescence decay measurement  
A spectrometry instrument, e.g., for time-resolved spectroscopy, has quick-change exchangeable accessories (48, 50, 52) which are manually attached via rotation of a camming means to engage and...
6657721 Method for quantitative analysis of atomic components of materials by LIBS spectroscopy measurements  
A method based on the LIBS technique is described, which allows to determine, without calibration of the measurement system, the concentration of atomic components in solid, liquid and aerial...
6654119 Scanning spectrophotometer for high throughput fluroescence detection  
A fluorescence spectrophotometer having an excitation double monochromator, a coaxial excitation/emission light transfer module, and an emission double monochromator. Each monochromator includes a...
6653152 Sensor disk having radial grooves and optical assaying method using same  
An optical assaying method and system having a movable sensor is described. In one aspect, the present invention is a sensing system having a rotating sensor disk coated with indicator dyes...
6649361 Surface plasmon resonance enzyme sensor  
A surface plasmon resonance enzyme sensor including a sensing part 6 having an optically transparent base 1, a thin metal film 2 made of gold or silver, and a film 4 provided on the metal thin film...
6650411 System, method, and product for pixel clocking in scanning of biological materials  
Systems and methods are described that may be applied to scanning biological materials in or on probe arrays. For example, a system is described that includes a scanner that has one or more...
6643015 System, method, and product for symmetrical filtering in scanning of biological materials  
An apparatus is described that includes an emission signal detector and an emission signal filter. An excitation beam scans an array of biological materials, and the emission signal detector...
6636304 Laser induced fluorescence capillary interface  
An optical scheme that substantially eliminates spherical aberration and coma, thereby substantially improving fluorescence excitation and collection efficiency. The optical scheme utilizes a laser...
6629464 Laser shock peening quality assurance by acoustic analysis  
A method for quality control monitoring of laser shock peening a surface of a production workpiece during which laser beam pulses form a plurality of corresponding plasmas. An acoustic signal of...
6624887 Methods for determining the physiological state of a plant  
The present invention provides methods for measuring a photosynthetic parameter. The methods of the invention include the steps of: (a) illuminating a plant leaf until steady-state photosynthesis...
6621575 Method and device for analyzing molecular reaction products in biological cells  
A large number of cells can be evaluated in terms of their reaction state with molecular reactants under near-field optical conditions in a measuring and evaluation procedure of the invention....
6614525 Laser scanning microscope with single wavelength excitation  
A laser scanning microscope, preferably a confocal laser scanning microscope, having a laser light source for illuminating a specimen and a detector for detecting the light returning from the...
6603547 Method for determination of the radiation stability of crystals  
The method for determining radiation stability of a crystal to radiation of a working wavelength to be employed in a subsequent application includes taking a first absorption spectrum (A) of a...
6573107 Immunochemical detection of an explosive substance in the gas phase through surface plasmon resonance spectroscopy  
The biosensor involves a specially designed surface which can be optically coupled to a Surface Plasmon Resonance spectrometer. The key components of the biosensor are a bimetallic layer, a self...
6571118 Combined fluorescence and reflectance spectroscopy  
Methods and apparatus for performing fluorescence and spatially resolved reflectance spectroscopy on a sample. A sample is irradiated with a fluorescence excitation fiber and radiation is collected...
6567164 Entangled-photon microscope and confocal microscope  
The invention discloses an entangled-photon microscope (1) having a light source (3) and an objective (31). The entangled-photon microscope (1) has a microstructured optical element (11), in which...
6551451 Method for determining liquid content in chemical pulps using ramen spectrometry  
A rapid method is provided for the on-line spectroscopic determination of lignin content and/or kappa number in wood pulps. Unlike currently available commercial instrumentation, the method enables...
6538735 Method and apparatus for producing and measuring light and for determining the amounts of analytes in microplate wells  
An apparatus for measuring light in samples using a high intensity light source, is presented. The system utilizes bifurcated fiber bundles to transmit light at the excitation and emission...
6532068 Method and apparatus for depth profile analysis by laser induced plasma spectros copy  
In a method of spectrochemical depth-profile analysis of heterogeneous materials, a first burst of ablation laser pulses in a first beam is directed at a sample to form an ablation crater. A second...
6532067 Aerosol fluorescence spectrum analyzer for rapid measurement of single airborne particles  
A method for fluorescence probing of particles flowing in a fluid includes defining a trigger volume in the fluid by intersecting a plurality of substantially orthogonally aimed trigger laser...