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7158225 Multi-channel, self-calibrating fiber-coupled raman spectrometers including diagnostic and safety features  
A multi-channel, reconfigurable fiber-coupled Raman instrument uses fiber optic switches for laser and calibration light routing to facilitate automated calibration, diagnosis and operational...
7158227 Laser-induced fluorescence analysis device and separation apparatus comprising same  
A laser-induced fluorescence analysis device (1), comprising a tube (2) including a channel, elements projecting an excitation light (13), optical collecting member (7), optical measurement...
7154102 System and methods for detection and identification of chemical substances  
The invention provides a system and method utilizing, among other things, fluorescence spectroscopy in the ultraviolet portion of the electromagnetic spectrum to determine chemical species and...
7153475 Aerosol particle analyzer for measuring the amount of analyte in airborne particles  
Aerosol particle analyzer (APA) for measuring the amount of analyte in airborne particle is described. The APA uses an analysis liquid. In most embodiments, this analysis liquid is chosen so that...
7151633 Scanning microscope  
A detector, arranged in the detection beam path of a scanning microscope, for the detection of detected light proceeding from a sample can be used to detect other than the detected light for...
7141801 System and method of illuminating living cells for imaging  
A system and method of providing illumination for a cell imaging system delivering modulated light for illumination of a sample. Modulation of illumination intensity may be effectuated by pulsing...
7138280 Masking of the background fluorescence and luminescence in the optical analysis of biomedical assays  
In a process for the quantitative optical analysis of biological cells labelled with a fluorescent dye, the sensitivity of analytical detection can be considerably improved if a masking dye, which...
7136161 Component analyzing apparatus with microchip  
A component analyzing apparatus includes a microchip having a fine separating flow path for separating components when a sample solution labeled with fluorescence passes therethrough. A light...
7130043 Laser scanning microscope and indicator discriminating method  
A laser beam is scanned on a sample while a wavelength of the laser beam is varied. Quantity of fluorescence from the sample is detected. Absorption wavelength spectral characteristic data of...
7130042 Dual axis fluorescence microscope with modulated input  
A dual beam confocal microscope is provided. An optical source assembly provides two mutually coherent optical beams differing in frequency by a frequency difference Δf. The two beams are received...
7119898 Method for the detection of fluorescent light  
A method for the detection and evaluation of the light generated in a fluorescing specimen by a short pulse laser, wherein at least a first and a second fluorophore and/or a self-fluorescing...
7115885 Method and device for multi photon excitation of a sample  
In a method for multi photon excitation of a sample a laser beam is split into at least two coherent partial beams each having a beam axis and a same intensity distribution about its beam axis....
7116417 Spectrometer and method for correcting wavelength displacement of spectrometer  
A spectrometer for correcting a displacement of a dispersed light image having a light source for outputting a monochromatic ray of light, an optical system which images a dispersed light image of...
7113277 System and method of aerosolized agent capture and detection  
System and method of aerosolized agent detection. Multi-part collection tape is employed for capturing particles of interest for immediate analysis and optional forensic preservation and recording...
7110111 Controlled wide spectrum compact ultrabrief laser source  
A wide-spectrum compact ultrabrief laser source includes a rare-earth ion primary laser. The source is pumped by a pump light flux centered on a wavelength λD, the flux being emitted by a solid...
7106439 Elementary analysis device by optical emission spectrometry on laser produced plasma  
This device comprises a pulsed laser source (6), means (8, 10, 12) for focusing light from this source onto an object to be analysed (2) to produce plasma on the surface of the object, means (16,...
7098041 Methods to view and analyze the results from diffraction-based diagnostics  
An analyzer useful in determining the presence of an analyte using a diffraction based sensing device and methods and systems using this device. The present invention may be used with a variety of...
7092083 Apparatus for presenting a sample of material for analysis  
An apparatus for presenting a sample of material for analysis by a laser-based analyzer comprises a chamber, a first window for admitting laser radiation to the chamber, sample presentation means...
7092087 Laser-induced breakdown spectroscopy for specimen analysis  
The present invention is directed to an apparatus, a system and a method for detecting the presence or absence of trace elements in a biological sample using Laser-Induced Breakdown Spectroscopy....
7088435 Controlled substance detection and identification system  
A system for detecting controlled substances on an object including at least one laser for illuminating at least part of an object with laser energy and either a second harmonic detector or a...
7084409 Sensing device and method for measuring emission time delay during irradiation of targeted samples utilizing variable phase tracking  
An apparatus for measuring emission time delay during irradiation of targeted samples by utilizing digital signal processing to determine the emission phase shift caused by the sample is...
7079240 Photonic crystal laser sources for chemical detection  
A system, method and apparatus provide the ability to detect a chemical in an analyte. To detect the chemical, the invention utilizes a laser having an open cavity. A photonic crystal lattice...
7070920 Screening arrangment for screening immunoassay tests and agglutination tests  
A screening device for performing an immunoassay test to detect the presence of a compound in a body fluid. The device includes a holder for removably receiving a membrane to which the fluid has...
7068367 Arrangement for the optical detection of a moving target flow for a pulsed energy beam pumped radiation  
The invention is directed to an arrangement for the optical detection of a moving target flow for pulsed energy beam pumped radiation generation based on a plasma. It is the object of the...
7063952 Masking background flourescence and luminescence in optical analysis of biomedical assays  
In a process for the quantitative optical analysis of fluorescently labelled biological cells 5, a cell layer on a transparent support at the bottom 2 of a reaction vessel 1 is in contact with a...
7064825 Methods and apparatus for evaluating rotary machinery  
A method for determining a useful life applied to a coating on a surface of a component coupled to a rotatable member of a rotary machine. The method includes directing a laser across a surface of...
7064827 Optical tracking and detection of particles by solid state energy sources  
A particle detector has a chamber defining a pathway that a target particle follows between an entry and an exit point, a solid-state energy source such as an LED, and a re-emission sensor. The...
7064824 High spatial resoulution imaging and modification of structures  
In a method of high spatial resolution imaging or modifying a structure, the structure is marked with a substance which is selected from the group of substances which can be transferred from a...
7059766 Optical device and method for the non-intrusive measuring of the temperature of a flowing liquid  
An optical method, and an optical device based on a laser source for implementing an optical method, for nonintrusively measuring the temperature of a flowing liquid by using the fluorescence...
7062311 Fluorescence observing apparatus  
A fluorescence observing apparatus including a light source for emitting excitation light, an excitation light irradiation section for irradiating the excitation light to a sample, and a...
7057712 Analysis systems detecting particle size and fluorescence  
Particle analyzing systems with fluorescence detection are disclosed, primarily in connection with particle sizing based on scattered light intensity or time-of-flight measurement. In one system,...
7038193 Method and device for separating different emission wavelengths in a scanning microscope  
A method for separating different emission wavelengths in a scanning microscope includes scanning a specimen with an illuminating light beam by passing the illuminating light beam over the...
7038768 Optical measuring method for semiconductor multiple layer structures and apparatus therefor  
In a measuring apparatus for a semiconductor multiple layer structure, a spectrometer disperses light from a sample for measurement of the photoluminescence spectrum or disperses probe light to...
7027150 Apparatus for measuring the concentration of a species at a distance  
Corrosion of refractory silica brick and air quality issues due to particulate emissions are two important glass manufacturing issues that have been tied to sodium vapor and its transport...
7022515 Waveguide immunosensor with coating chemistry and providing enhanced sensitivity  
Methods and apparatus for evanescent light fluoroimmunoassays are disclosed. The apparatus employs a planar waveguide and optionally has multi-well features and improved evanescent field...
7019830 Process and apparatus for qualitative and quantitative analysis of an analyte  
A process for qualitative and quantitative analysis of an analyte in a solution includes irradiating a first chromophore with an electro-magnetic radiation while simultaneously moving an...
7019831 Separation device substrate including non-fluorescent quencher dye  
A device is provided for the analysis of samples. The device includes a plurality of sample-containment features and a non-fluorescent quenching material for minimizing cross-talk between optical...
7016523 Method for observing object by projection, method for detecting microorganisms and projection detecting system  
Fast microbial detection is accomplished by identifying quantities of microorganisms accurately and easily. A cell 5 is placed on a loading portion. A coherent laser beam source 2 emits laser beam...
7016035 Fiber optical apparatus and system for in situ laser plasma spectroscopy  
In in-situ laser plasma spectroscopy (LPS) apparatus includes an enclosure for housing a laser energy source and associated signal coupling optics. A main fiber is attached to the enclosure at a...
7015485 Laser scanning microscope, semiconductor laser light source unit, scanning unit for a laser scanning microscope, and method of connecting semiconductor light source to scanning microscope  
A laser scanning microscope according to the present invention is a laser scanning microscope which scans a laser beam on a sample by a scanning optical system in a scanning optical system main...
7012687 Spectral analysis with evanescent field excitation  
An apparatus includes an optical fiber and a light collection device. The optical fiber has an untapered segment and a down-tapered segment. The light collection device has an optical aperture...
7009699 Method for investigating a sample  
A method for investigating specimens, wherein a spectral splitting of the radiation coming from the specimen is carried out for specimen points or point distributions, for the operation of a laser...
7006216 Device for the chemical analysis of material samples and metallurgical vessel therefor  
A device for the chemical analysis of solid or molten material samples, based on laser-induced emission spectroscopy, including a laser source generating a laser beam, a deflection device...
6998598 Modular optical detector system  
A modular optical detector system. The detector system is designed to detect the presence of molecules or molecular species by inducing fluorescence with exciting radiation and detecting the...
6992762 Method and apparatus for time resolved optical imaging of biological tissues as part of animals  
There is provided a method and system for collecting optical data for use in time resolved optical imaging wherein light is directionally propagated through free-space optics to impinge on a...
6992303 Detecting emitters of electromagnetic radiation, in particular fluorophore labeled substances  
The performance of devices for the detection of fluorophore labelled substances in an electrophoretic separation medium is improved by rescanning lines or pixels which caused saturation of an...
6987564 Automatic correction for continuum background in laser induced breakdown and Raman spectroscopy  
The approximation of a spectral continuum by determining a plurality of minima in the spectral data; splitting the spectral data into a predetermined number of groups N; for each group of spectral...
6987568 Apparatus and method for measuring spatially varying bidirectional reflectance distribution function  
An apparatus and method for measuring spatially varying bidirectional reflectance distribution function and method are provided. The apparatus and method provide means to illuminate different...
6980294 Biomolecule analyzer  
A biomolecule analyzer of the present invention analyzes dynamic behaviors of biomolecules, and comprises image obtaining means for obtaining an image corresponding to at least one observation...
6979830 Optical architectures for microvolume laser-scanning cytometers  
Methods and instrumentation for performing charge coupled device (CCD)-based confocal spectroscopy with a laser spot array are provided. The methods and instruments of the invention are useful in...